NootBro
@nootropicguy • 83,717 subscribers
Biohacking, supplements, nootropics, & peptides for peak performance. Followed by @HubermanLab. Tweets are not medical advice.
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What people think Shilajit does: - Contains 84+ minerals What Shilajit actually does based on scientific studies: 1) SUPERCHARGES MITOCHONDRIA - Reduces fatigue (in CFS) - Contains dibenzo-a-pyrones (DAPs) - DAPs = mitochondrial superchargers - Synergizes with & increases CoQ10 - Upregulates mitochondrial enzymes - Protects mitochondrial membrane - Normalizes mitochondrial respiration - Reduces excess nitric oxide - Increases ATP energy levels - Anti-apoptotic (cell death) - Increases glutathione levels 2) HORMONAL & PHYSICAL ENHANCER - Aphrodisiac effects - Boosts testosterone by ~20% - Increases DHEA-S - Increases FSH - Improves sperm count/motility - Testicular antioxidant/inflammatory - Modulates stress (via HPA) - Increases corticosterone in CFS - Increases adrenal weight in CFS - Increases genital blood supply - Improves erectile dysfunction - Preserves muscle strength - Pro-connective tissue (in humans) - Upregulates collagen synthesis 3) ENHANCES COGNITIVE HEALTH - Increases dopamine (blocks 5-HT2C) - Anti-anxiety (via GABA/Glycine) - Anti-epileptic (via GABA) - Reduces alcohol intake - Reduces drug tolerance/withdrawal - Anti-Alzheimer's (tau formation) - Disassembles tau proteins 4) ENHANCES GUT & METABOLIC HEALTH - Reduces leaky gut (via fulvic acid) - Reduces gut inflammation (IL-6) - Anti-ulcer (via fulvic acid) - Anti-glyphosate activity - Mild anti-SIBO (via benzoic acid) - Enhances nutrient absorption - Increases digestive enzymes - Reduces high blood glucose - Reduces total cholesterol - Boosts HDL (humic acid especially) - Chelates heavy metals & toxins 5) ANTI-VIRAL & IMMUNOMODULATORY - Inhibits SARS-CoV-2 - Inhibits HIV (humic acid especially) - Anti-HSV-1 (cold sores) - Anti-allergic - Stabilizes mast cells - Improves eczema (via fulvic acid) - Improves skin health (in humans) - Anti-arthritic (in rats) - Anti-arthritic pain (in dogs) A FEW NOTES - Many claims are w.r.t. fulvic/humic acids - Shilajit minerals = 90% Mg/K/Ca - Overrated mineral source IMO - Shilajit is often 60-80% fulvic acids - Most research is animal studies - Some contain mycotoxins/heavy metals - Consult a doctor prior to using - Ask me for a study for any claim MY PERSONAL EXPERIENCE? - Very noticeable effect - Natural energy (unlike caffeine) - Potent aphrodisiac - I've used Based for ~ 1yr - Third-party tested for purity - My 10% off code = NOOTBRO - 4 tablets, 5 days/wk in spring water - Best to cycle off every few weeks
NootBro763,490 Aufrufe • vor 2 Jahren
What people think Methylene Blue is: - Fish tank cleaner What Methylene Blue actually is based on 100+ years of use in humans & 18,000+ scientific studies: 1. NEUROPROTECTIVE - Ongoing clinical trial for Alzheimer's - Antidepressant (humans: 15mg) - Promising anti-bipolar effects - Mild anti-schizophrenia properties - Anti-Parkinson’s properties - Anti-Huntington’s properties - Anti-anxiety properties - Improves stroke recovery - Improves TBI recovery 2. BRAIN MITOCHONDRIAL ENHANCER Almost all of the neuroprotective benefits listed above are a result of MB's ability to: - Reduce nitric oxide (too much is bad) - Reduce oxidative stress (antioxidant) - Donate electrons in mitochondria - Increase the number of mitochondria - Recycle old/damaged mitochondria As a result of this, Methylene Blue can: - Reduces neuroinflammation - Increase neurogenesis (BDNF) - Restore GDNF in Parkinson’s - Reduce amyloid & tau - Fortify blood-brain barrier - Improve cerebral blood flow Methylene Blue can also inhibit MAO-A enzymes and to a lesser extent MAO-B enzymes This boosts levels of dopamine, norepinephrine, & serotonin 3. COGNITIVE ENHANCER But Methylene Blue isn’t just a neuroprotective agent It’s also an cognitive-enhancer In human studies, MB has been shown to: - Improve attention span - Improve short-term memory - Enhance fear extinction (Anxiety/PTSD) I definitely feel sharper on 5-15mg of MB 4. ANTI-MICROBIAL & IMMUNOMODULATORY MB isn’t just a nootropic It’s actually one of the world’s best anti-microbial agents I personally used 30mg/day 2 weeks ago to annihilate the flu Went from down bad to back on my feet in about 24 hours - Improves COVID-19 treatment - Pulled C19 patients off respirators - Inhibits SARS-CoV-2 replication - Inhibits H1N1 replication - Cures malaria in ~48 hours - Kills parasites & fungal infections - May have anti-cancer properties - Reduces chemotherapy side effects Plus when it’s combined with light, MB: - Inactivates herpes virus - Inactivates zika virus - Reduces Hepatitis A & C levels - Reduces ebola infectivity - Reduces HIV-1 to undetectable levels 5. SKIN ENHANCEMENT - Very underrated skincare tool - Superior to Vit C + Retinol - Use MB tallow balm for skin - Will link my full guide below 6. MY PERSONAL EXPERIENCE - I’ve been taking MB for ~6 months - Best results combining with light - Feels very nourishing in a sense - Noticeable acute energy boost - Brain fog dissipates immediately - Heightened senses (vivid colors) - I use Meraki Blue Tongues - 10% off code = NOOTROPICGUY - USP-grade & heavy metal free - 5 mg orally per day 5x per week - 2-4 week break every 8 weeks 7. SAFETY Methylene Blue is extremely safe when used correctly In fact, it’s been used safely in humans for 100+ years: - First synthetic medicinal drug - Dozens of human clinical trials - Attractive safety profile - FDA-approved (methemoglobinemia) - Reverses cyanide poisoning - Reverses carbon monoxide poisoning With that said, there 3 key caveats: - Microdose to avoid pro-oxidant effect - Never combine with SSRI/SNRI drugs - Don’t use with G6PD deficiency - G6PD deficiency = hemolytic anemia 8. DISCLAIMER - This is not medical advice - Consult a physician prior to using - Methylene Blue will stain if spilled - Will temporarily stain tongue & pee blue - Only use USP-grade w/o heavy metals
NootBro542,766 Aufrufe • vor 2 Jahren
The Androgenic Dream Team Cheatsheet 1. The Top 10 Testosterone Boosters 1) Tongkat Ali (LH, enzymes, anti-SHBG) 2) Fadogia (boosts LH via pituitary) 3) Cistanche (LH + steroid enzymes) 4) Akarkara (boosts LH via pituitary) 5) Shilajit (mitochondrial enhancer) 6) Sunlight (skin-brain-gonad axis) 7) Forskolin (cAMP steroidogenesis) 8) Bulbine Natalensis (toxicity risk) 9) Suma (anabolic + androgenic) 10) Panax Ginseng (mild test/DHT boost) 2. Key Androgenic Minerals - Boron (frees up test from SHBG) - Zinc (ARs & anti-E2/prolactin) - Magnesium (Mg-ATP + enzymes) 3. Important Androgenic Vitamins - Vit D (androgen receptor signaling) - All influence steroidogenesis - Full post coming soon on this 4. Testicular Antioxidant Supplements - NAC - Taurine - Selenium - Astragalus - Vitamin C (organic) - Vitamin E (mixed tocopherols) By reducing testicular oxidative stress, these tools help prevent testicular dysfunction & support Leydig (testosterone) & Sertoli (spermatogenesis) cell function 5. Culinary Test Boosters - Ginger (testicular antioxidant) - Onions (boosts steroid enzymes) - Honey (testicular antioxidant + LH) - Cocoa (steroidogenic flavonoids) - Oysters (zinc + taurine) - Dates (boron) - Garlic (LH via diallyldisulfide) - Pastured eggs, meat, etc 6. Overrated Testosterone Boosters - Ashwagandha (anhedonia) - Maca (libido only) - Horny Goat Weed (erections only) - Fenugreek (reduces DHT) - Pygeum (reduces DHT) - Saw Palmetto (reduces DHT) - Cordyceps (weak effect in humans) - Spilanthes Acmella (weak effect) - Kisspeptin (low ROI) - Gonadorelin (low ROI) - Selenium (weak effect if any) 7. Other Androgenic Herbs & Nutrients - L-Carnitine (upregulates ARs) - Tribulus (boosts DHT via protodioscin) - Butea Superba (increases DHT) - Date Palm Pollen (increases test) - Mondia Whitei (androgenic aphrodisiac) - Kali/Safed Musli (fertility + boosts test) 8. Lifestyle Factors - Sleep & Circadian Rhythm - Micro/macronutrients - Testicular EMF Exposure - Testicular temperature - Weight training - No cooming (prolactin + reduces ARs) - Avoid stress (breaks down ARs) - Sunlight Exposure 9. Enhanced Tools - Full thread coming soon - Anabolic steroid series soon too
NootBro444,144 Aufrufe • vor 2 Jahren
What I’m taking to get shredded before New Year’s Day: - 500mg L-Baiba (exercise in a pill) - 200mg DHB (Berberine on steroids) - 300mg Black Ginger (elite fat burn) - 180mg GOP (#1 anti-obesity herb) - Agmatine + C3G (nutrient partition) - Testncrease + Tribugen (DHT) Semi-natty: - 50mg MOTS-c (exercise in a vial) - Inj. L-Carnitine (fat oxidation + ARs) - Ipa/CJC no dac (growth hormone) Not so natty: - HCG (androgen signaling) - Anavar (anabolic of choice) Don’t fall for the Yerba Mate psyop anon
NootBro41,597 Aufrufe • vor 1 Jahr
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