A few years ago, designing an antibody on the... computer was extremely difficult. Today, there are several open-source tools which allow anyone to design antibodies from home. Out today: A step-by-step guide to antibody design. By Brian Naughton.show more

We're going back to basics today. 🤓 Designing your... first button is a rite of passage and a great way to get hands-on practice when starting your design journey. Here's a step-by-step guide to get you started.show more

Confirming the Princess’ coat today was by Chris Kerr,... from cloth woven by Johnstons of Elgin especially for HRH. The Princess worked with Johnstons of Elgin on the design of the fabric, a sign of her determination to celebrate British textiles and design.show more

Today we’re thrilled to announce JAM-2 — the first... AI model capable of generating drug-quality antibodies straight from the computer, with industry-leading success rates. > Drug-like affinities: Picomolar to single-digit nanomolar antibody binders for half of 26 targets while testing Unlocking hard targets: Up to 11% success rate for direct on-cell GPCR binders; top antibody hits in the single-digit nanomolar range. > Unprecedented epitope breadth: JAM-2 routinely designed antibodies that hit 30–70% of user-defined epitopes, now enabling intentional design of biology — not chance discovery. > Drug-like developability: Over 50% of antibody designs passed core industry developability criteria with zero optimization. > Massive leverage: A four-person team prosecuted 16 targets in parallel in < 1 month. JAM-2 is the first de novo antibody design capability ready for front-line use in drug discovery, matching or surpassing traditional discovery approaches. We’re already deploying JAM-2 with multiple large pharma partners and seeing excellent results. If you’re interested in partnering on molecule development or accessing JAM-2, contact [email protected]. Read more in our whitepaper (link below)show more

Today we're excited to announce the open sourcing of... an early version of Gastronomy, our UPLC debugger, a Fund 12 project! This allows a Cardano developer to take a UPLC program, and walk through its evaluation, step by step, forwards and backwards!show more

Here's an example of a creation by GLM 5.2... on Design Arena, made from only one prompt. Just six months ago, there was a big enough difference between open and closed weight models that we considered having two separate evaluations. Open weights have come a long way. Congrats to the Z.ai team for this achievement!show more

Many drugs work by binding to a specific target... in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work. We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets. We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.show more

The new Cofounder site is literally a step-by-step guide... on how to start a company. When i started my first company there was all sorts of stuff i had to learn and all of the guides were SEO maxxed slop. Now there's a real one written by experts and u can download it.show more

The #NHLBruins are extremely saddened by the tragic passing... of BP-Southeastern goalie Dylan Quinn, who was a volunteer at several of our Learn to Play clinics over the years. Our hearts are with his family, friends, and teammates during this difficult time.show more

From product image to video with just one tool... - Dzine As you may have noticed, this is one of my favorite tools. It is also very underrated, as probably 50% of my tutorials include some workflow. I was testing the new image-to-video option today, and I love it. Step - by step guide in comments 🔽 I can do 95% of a workflow without switching between apps. Image generation, Image to image with style reference, background removal, background generation, and 2 frames image to video. The only other app I have been using for this video is CapCut so that I can stitch it together. Step by step 🔽show more

Want to learn how to make a game like... this using AI? &gt; Backgrounds &gt; Sprites &gt; Animations &gt; Music &gt; Code Full step-by-step tutorial landing TODAY. Check out gameplay video below 👇 🔈 Sound ON for maximum vibesshow more

We are proud to announce our first contribution to... open source Computer Vision research! 🚀 Today, we’re publishing on Hugging Face a 1,000 3D Maps Dataset under CC-BY-NC license, designed to accelerate progress in 3D perception and spatial AI. Our way to give back to the global AI community and show how DePIN can make an impact. 🧵 👉show more

how to take care of your jin-hyung so he... knows you love him: a guide by jeon jungkook step 1: remove his shoes [your jin-hyung won't fight back] step 2: make them a vase step 3: push your jin-hyung on the couch if he tries to stand to prevent him from getting his shoes backshow more

This snow leopard was filmed a few years ago... in the Himalayas by Prasenjeet Yadav. The internsity of the expression on his face and his eyes are a unique documentation of observation in the wild. [source, read more:show more

Comment ‘BOOM’ and I will give you the step-by-step... guide to do the same On tour my driver clubhead speed was barely above 110mph. Last year, I reached a new PB of 131.2mph and reached a ball speed of 191mph with the help of fellow coach This came purely fromshow more