Literally shows normal snipes are allowed but I got... perma banned???? This game is a normal snipe not a stream snipe since hypno ended stream hours ago. This ban is unfair and wrong. Only banned because super creator lied to the devs. Player tag #8022RY8YU Emilia Donald Smith Jr.show more

This is bad. Content Creator ItsHapa was correct COD... cheaters still have access to CRASH YOUR GAME, and perm ban your account. Yesterday my friend 8Blurr was trash talking hackers they said “enjoy ur perma ban” he’s now Perm banned and forced to buy a new PC Those cheaters bragged about it the next game in ranked play when they played blurr’s friendshow more

Some microbes carry a protein, called SNIPE, that "chops... up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.show more

I would rather not continue this conversation, but I... felt this needed to be highlighted. Why are we Supporting sniping in videos/on stream, Especially as a big streamer? Stream sniping is already happening a lot, and talking about how fun it is on stream just makes it worse.show more

bro goes on a tangent on stream, talking about... not just me but multiple others in this manner WHILE STREAMING IN THE FFXIV CATEGORY, and between doing PF content and then is surprised he was banned for being "hateful" while playing the game LOLLL the jokes write themselvesshow more

I cannot emphasize enough how much the vibes have... changed & everyone's priors on what is normal are wrong. This was posted by a religious page - not political one - & got almost 1 mil views in 24 hours. And no fighting in the comments or anything. It's not even controversial.show more

Is Jane Hume even aware that Australia has banned... tobacco advertising for decades and we have the lowest smoking rate in the world? We are the biggest gamblers per capita but she reckons a blanket ban on gambling “is not the Australian way”. The Libs are just pathetic on this.show more

🚨 MARTHA STEWART SAYS SHE BITES HER PUPPIES ON... THE MOUTH HARD “UNTIL THEY SQUEAL” — AND THE INTERNET IS LOSING IT Martha Stewart is on camera holding a puppy… smiling… and then casually says: “I bite the animal right here on its mouth hard… and it squeals.” She says that’s how it knows she’s the mother. This isn’t off-camera. This isn’t taken out of context. She says it like it’s completely normal. And the reaction? The internet is split and it’s getting heated. “This is weird as hell” “She shouldn’t be allowed to own a pet” “She learned this in prison” “WTF did I just watch?” But then others are pushing back: “Dogs do this to each other… y’all are overreacting.” “This is literally how animals establish dominance.” Half the internet thinks this is completely normal. The other half thinks it’s insane she said it out loud. Is this normal behavior… or is this crossing a line?show more

I wonder if FPS HUB knows the streamer they... are reportedly discussing a sponsorship with has repeatedly been banned and is accused of actively cheating? DarkAlpha_xDi appears to have switched to DMA cheats after his other accounts kept getting banned. Below is the clip of him discussing the sponsorship, along with screenshots documenting the banned accounts. FPS HUB is this someone you want representing your company? How can you watch this guy's gameplay and NOT see he is blatantly hacking on CoD?show more

I don’t normally post this stuff, because I get... weird and strange DMs every day, but I want everyone to see how abnormal people like CTS1 are on here. This is not normal behavior, and it deserves to get called out. I have no problems when others do the same.show more

For anybody wondering what is going on with $CANCER... live stream... my life was saved for whole 24 hours untill someone tuned in my stream and got me to download verified game on Steam After this I was drained for over 32,000$ USD of my creator fees earned on @pumpdotfun and everything quickly changed. I can't breathe, I can't think, im completely lost on what is going to happen next, can't shake the feeling that it is my fault that I might end up on street again or not have anything to eat in few days... my heart wants to jump out of my mouth and it hurts. I won't rewatch this myself but I have added a clip from the stream after I noticed what has happened. also I have succesfully (CTOed) my creator rewards and they have been redirected to safe device. alonshow more

This game is tied at 2-2 in the eighth.... Aaron Ashby got a bouncer that should have ended the inning, but Jake Cronenworth beat him to first base and Fernando Tatis Jr. never stopped running. Dustin May pitched well enough to win today, but will not.show more

I went outside to do my grounding and soak... in the sunlight this morning. I couldn't help notice this. This isn't normal. These are not condensation trails. They aren't disappearing. I never saw this as a kid growing up. What are these, why and who is doing it?show more

I do not know where this loser David Allen... Snyder Jr rolled in from but no way this clown is from South Florida. Literally attacking a car because it has a US flag?? Spitting on the people and taking a shot at their car?? Shocked he is still alive tbhshow more

So British Airways this is a joke .. we... land into Heathrow and there are no slots to park the plane . We then find a slot but its not attached to a gate so we to wait for a bus as there are no buses. Three buses finally show up and because there is now a shower someone has decided that any arrival which has steps and a bus, passengers are not allowed off the plane … this is ridiculous , the weather forecast says its going to rain for the next three hours .show more

i hate to say it but this is how... you know he's not one of the girlies bc this is something i'd talk ab over a normal dinner? like the convos i've had w my friends and roommates... HE'D NEVER GET ITshow more

Comparing the two different times we saw the skirt... camera and it's very obvious the flames are more apparent later on. I didn't want to jump to conclusions because entrained fuel burning is normal on many rockets, but this clearly got worse showing that the failure progressed.show more

This issue is suddenly back... Periodic stutters that are... hard to notice in a video but you feel them and they make the game unplayable Happens when PC is on for a while, not the game itself. Only reliable fix is to restart PC To clarify, this wasn't issue in the pastshow more

I'm not saying this needs to be "fixed", it's... a part of basketball. But what I would suggest is adding the "Challenge Call" feature to 5v5 game modes, because this is not a foul, and would be reversed 9/10 times in MyCareer.show more