The axonal cytoskeleton and other components. The structural support... is provided by spectrin and actin near the cell membrane. Microtubules, form tracks and motor proteins utilize them. A real axon is far more complex, housing essential structures like mitochondria.show more

#FluorescenceFriday #cellbiology #bioart The actin cytoskeleton at 60 nm... resolution and 3 frames/min, and its association with early endosomes (Rab5a, green), as seen in a COS-7 cell by photoactivated nonlinear structured illumination microscopyshow more

Our atmosphere is powerful, complex, and sometimes just straight... up.... freaky. Open and closed cell stratocumulus oscillate as ships cut through them forming tracks in the clouds.show more

Nice example of actin retrograde flow in a gigantic... lamellipodium. #cytoskeleton, #actin, #microscopy, #cell-motility, #scienceshow more

Actin isn’t just structural, it’s dynamic. In this video,... the cell deliberately dismantles its intricate, maze-like ridges to divide, then rapidly rebuilds the same complex pattern afterward. No blueprint, no pause just molecules sensing context and snapping back into order.show more

This time-lapse captures 17h of axonal growth from a... chick dorsal root ganglion explant, seen through the actin cytoskeleton using live imaging. I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours!😉 #neuroscienceshow more

Inside every cell, there is a transport system that... determines how materials move, signals propagate, and structure is maintained. This video captures that system in motion. The glowing streaks mark the growing ends of microtubules (protein polymers that constantly assemble and disassemble through a process called dynamic instability). Rather than forming permanent tracks, microtubules are rebuilt continuously, allowing cells to reorganize their internal layout in real time. This behavior is essential for life. Cells rely on microtubule dynamics to divide accurately, migrate during development and repair, and maintain long-distance transport in neurons that may span over a meter in length. When this system is altered, the consequences are significant. Certain cancer therapies work by locking microtubules in place, preventing cell division. In contrast, failures in microtubule transport are linked to neurodegenerative conditions (like Alzheimer's) where intracellular delivery breaks down. What appears as abstract motion under a microscope is actually one of the core systems that keeps cells functional, adaptable, and alive. Video Credit: Andy Mooreshow more

Let’s take a closer look at this protein structure... determined using AlphaFold2. This protein structure is part of a huge molecular structure in the human body. More than a thousand proteins form a pore through the membrane surrounding the cell nucleus. Animation: ©Terezia Kovalova/The Royal Swedish Academy of Sciences #NobelPrizeshow more

Scientists may have just found the real key to... intelligence inside our mitochondria. And no, it’s not microtubules. It’s something eerily similar: Dynamin.show more

This is a bacterial flagellar motor … one of... nature’s most sophisticated molecular machines - a rotary motor embedded in the cell membrane consisting of ~25-30 protein types totaling 20,000-50,000 atoms in a multi-part structure of rotor, stator, drive shaft, and propeller. Operating at 100-300 Hz (6,000-18,000 RPM) with some species reaching 1,700 Hz (~100,000 RPM) at nearly 100% efficiency, this nanoscale engine features rotor proteins FliG/FliM/FliN forming the C-ring, MotA/MotB stator complexes, FlgG rod protein drive shaft, FliC flagellin propeller filament, and FlgE hook proteins acting as a universal joint, all powered by proton or sodium flow across the membrane generating torque through conformational changes in the stator complexes.show more

This mesmerizing timelapse captures the nonstop motion inside an... animal cell. Moving red/orange streaks are the growing ends of microtubules, tiny “highways” that move proteins & other molecules within the cell. 📸: Andy Moore, HHMI’s Janelia Research Campusshow more

A cell videoed through a microscope. DNA in the... nucleus (green) and the powerhouses/overlords of the cell, mitochondria (purple), are shown. #CellBiologyshow more

Senegal is facing a deep and structural financial crisis... in its higher education sector, reflecting the fragility of the country's economic and social structures under the influence of neoliberal policies.show more

Biggie is actin real entitled and I don’t like... that- #BaddiesCaribbeanshow more

✨In China, a construction site is covered by a... giant air-inflated membrane (like a big “balloon” outside) – it’s the foundation pit air membrane technique. It seals the area to control dust and resist weather, letting excavators and cranes work smoothly. Innovative engineering!show more

A cell videoed through a microscope. DNA in the... nucleus (green) and mitochondria (purple) are shown. #CellBiologyshow more

The most detailed 3D reconstruction of a cell ever... created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.show more

#FluorescenceFriday #cellbiology #immunology #Actin dynamics at the immunological synapse... (IS) between a Jurkat T cell and an antigen-presenting coverslip, as seen by total internal reflection structured illumination microscopy (TIRF-SIM). John Hammer's group #NIH used our TIRF-SIM to show that formins rearrange inward flowing actin filaments from the outer lamellipodial band of the IS into circumferential arcs that establish the peripheral supramolecular activation cluster, which in turn concentrates T cell receptor microclusters at the center of the IS.show more

Russian Telegram channels report a drone attack on Stavropol,... Russia. Signal plant was hit. Signal plant is a part of Russia's defense infrastructure, producing radio navigation equipment and other components for the Russian military complex. Signal is under EU, US, Ukraine and Japan's sanctions.show more

🔋 Mitochondria run their core power system using bacterial-style... DNA. 🧬 But they need your nuclear DNA for support, repair, and growth. Think of it like a battery with its own mini-engine — it sparks on its own, but the car (your cell) builds and maintains it. Bottom line: Mitochondria are semi-independent — powered by ancient bacterial genes, guided by your human ones.show more