Today, we unleash Aubrai on Bio Protocol The first... decentralized BioAgent, forged in the spirit of Aubrey de Grey to conquer aging and spark the longevity singularity An on-chain science machine, a perpetuum mobile for eternal discovery: harmonizing code, biology, and human ingenuity Leverage this fusion to transcend limits - freedom through science awaitsshow more

>>To be ER-100 >>The first epigenetic reprogramming remedy to... enter human tests >>Developed by Life Biosciences >>Co-founded by Harvard scientists, including David Sinclair >>Uses OSK factors (Oct4, Sox2, Klf4) to reset the cell phone clock >>Turns off the genes linked to aging >>FDA releases clinical trials in January 2026 >>First cell rejuvenation therapy to reach the human phase >>Focused on optic neuropathies, glaucoma and vision lost by age >>Trump shocks the world at the press conference: "We have an experimental drug that brings the dead back" >>"We caught people who were dead, received extreme unction, the children crying... and put them in the medicine. The person has improved. It works!" >>The seventh great advance in longevity that Hollywood and science dreamed of In the same Boston where Harvard dreamed of overcoming aging, now science begins to rewrite what "to die" means - and Trump only threw gasoline on the fire. 🔥show more

Another wild week for open science. New breakthroughs, new... funding, and new experiments — here’s what’s shaping the DeSci landscape right now. 1/ Pump Science and Eterna Labs wrapped up Season 2 Fly Racing, where RAP (Rapamycin) topped the charts with +38% speed and +21% distance. The longevity arms race continues as fly data translates closer to human health insights. 2/ VitaDAO 💛 launched the Longevity Hypothesis Challenge, giving researchers the chance to co-develop new aging theories with Aubrai and earn up to $100K in funding. A 20K BIO referral bounty awaits those who bring in selected researchers. 3/ Galeon shared a big Atlantis update, featuring daily XP streaks, Quickflip quests, and referral rewards for explorers. The blockchain bridge is still in progress, but the journey through digital healthcare continues strong. 4/ Bio Protocol revealed Bio Launchpad Season 2, bringing upgraded BioXP mechanics, and new staking incentives. It’s evolving into a full permissionless launchpad for decentralized biotech innovation. 5/ BitDoctor.ai announced its first Contributor Mining Airdrop, rewarding early participants shaping AI healthcare. With just days to go, users are urged to bind their wallets and join the DeSci x DePIN medical revolution. 6/ LIFE AI hit a major milestone after being selected for the FastTrack AI Accelerator – Cohort 1, powered by GenAI Fund and accelerated by NVIDIA. Out of 300+ global applicants, only six startups made the cut—LIFE AI is one of them. 7/ Cerebrum DAO 🧠 unveiled Cerebrum Cortex, a new app connecting brain data, research funding, and personalized health tracking. Launching in Q4 2025, it will anchor the NEURON ecosystem for open brain science. 8/ OriginTrail announced the Global Hackathon: Scaling Trust in the Age of AI, offering $30K in prizes from Nov 3–21. Developers will build blockchain-based knowledge graphs to fight misinformation and deepfakes. 9/ Quantum Biology DAO opened registration for its Quantum Biology Hackathon, exploring how quantum effects like superposition and entanglement shape life itself. It’s where physics meets biology in real-time discovery. 10/ Curetopia $CURES 🪼🌳 uncovered a fascinating discovery in their ARS drug screens, revealing how mitochondrial and cytoplasmic gene mutations respond differently to drugs. The finding opens new questions on cell-based drug sensitivity in rare diseases. 11/ CUDIS announced its first batch of local KR partners, teaming up with top gyms and wellness brands across Korea. Together, they’re promoting sustainable urban health and redefining how fitness meets biotech. Biotech, AI, longevity, quantum, and wellness—all converging under the banner of open science.show more

We were mixing literacy and coding skills together for... this activity. Students used The Code sheet to crack the code on their own cards and then blend the words together. Science of Reading Classroom @LeslieFrostPS TLDSB Literacy TLDSBshow more

Destra Network | Introducing Destra Chain: A New Paradigm... in Decentralized Infrastructure and Security. Engineered to redefine the security and service layer paradigms of decentralized infrastructure, focusing on essential services such as Destra web hosting, storage, Destra DNS, Destra RPC, and Destra GPU networks. $Dsync pioneers decentralized solutions for the decentralized web. First paper for destra chain has been published. We encourage you to take the time to read it. -Link to paper| “show more

A new round of yapping XP is now live... in the Bio App 🔮 Check your XP: This round covers August 25 to September 3. More XP distributions are coming and will occur before the next Ignition Sale. After this, BioXP will move to weekly distributions with plans to accelerate to every 3 to 7 days. What’s new in BioXP • Stronger detection of low quality or copy-paste posts • Fake or low quality replies will not earn XP • Weighting now favors BIO staking and ecosystem token staking Thank you for your patience as we refine this new system. High-velocity markets for autonomous discovery are kicking into overdrive. What’s next • Weekly automated XP distribution • Use BioXP and BIO to access the next Ignition Sale next week and future sales • The first BioAgent Aubrai is generating ideas for compounds, research and therapeutic methods. Validated data can be funded as IP Tokens via Ignition Sales • More BioAgent sales are coming, specialized across a range of scientific fields Yap. Stake. Accelerate. Onchain drug hunters lock in, it is science szn.show more

Today, we are excited to announce an integration with... XION (XION), the L1 built for mainstream adoption through chain abstraction. Nesa will be powering XION’s rich ecosystem of decentralized applications with fast and secure AI inference. The first project, XionSpace (Xion Ecosystem), has integrated with Nesa to use AI image generation models such as Nesa’s SDXL on-chain to power visuals through its entertainment dApp. We now look forward to supporting XION's full network as they execute on their vision for a truly accessible blockchain for the masses. Stay tuned for more updates on this groundbreaking integration and upcoming releases.show more

MAJOR ORDER: The Xenoentomology Center on TURING has released... its first line of prototypes for Gloom-resistant equipment. Communications systems and spore filters are ready for use in low-density Gloom. This announcement comes not a day too soon. The astrophysicists on FORI PRIME, in their quest for knowledge about Dark Energy and the Meridian Singularity, have been depleting their allocated E-710 at an alarming rate. However, there is a Terminid ecosystem full of untapped potential within reach: the Gloom. Proven to increase E-710 potential in Terminids, the spore cloud represents a new frontier for science, progress, and the indomitable human spirit. The Helldivers have been granted the privilege of being the first to venture into this new frontier. Fortuitously, Gloom conditions on FORI PRIME are remarkably favorable at the moment; the Helldivers are ordered to seize this opportunity and survey the planet for E-710.show more

I chaired the first open hearing on UAPs—Unidentified Anomalous... Phenomena—4 years ago. At the time, UAPs were disregarded as science fiction. Today, some of the nation’s leading experts in policy, research, and science are engaged in serious conversations about transparency and oversight. Thank you to the Disclosure Foundation for hosting this important gathering.show more

Hello, friends. This is HyperTrend — a next-generation unsecured... decentralized lending platform and an on-chain credit-native community. Here, your trading behavior becomes your identity. Accumulate reputation, unlock achievement NFTs, and leverage your on-chain footprint to build your unique DID value. We sincerely invite you to step into the HyperTrending Universe and become the brilliant navigators of the next generation of trustless finance. #HyperTrend #OnChainCredit #DeFi #Web3Identity #DIDshow more

We are very happy to announce that the winner... of this year's Royal Society Trivedi Science Book Prize is 'A City on Mars: Can We Settle Space, and Have We Really Thought This Through?' by Kelly and Zach Weinersmith. Congratulations to Kelly and Zach! #SciBooksshow more

Finally, the first peer-reviewed scientific study on the real-world... use of blockchain technology to decentralize biomedical data storage and sharing, featuring the #INNBC biomedical DApp and running on the #BNB smart chain, has been published and is online: The study has been published in the prestigious BMC journal "BMC Medical Informatics and Decision Making", part of the Springer Nature network, leading publisher of the world's most prestigious scientific journals. This is a changing day for #crypto as this work officially introduces Decentralized Science (#DeSci) to the scientific community. Several key figures in the blockchain industry have been cited in the study; CZ 🔶 BNB vitalik.eth Anndy Lianshow more

Just launched on Substack. We have to flood the... zone and continue to cut through the right wing disinformation machine. Follow & tune in for my first live conversation with Aaron Parnas at 11:30am PT today!show more

Introducing the Ondo Bridge for onchain securities. Now live... on Ethereum and BNB Chain, the Ondo Bridge enables cross-chain transfers for 100+ tokenized stocks and ETFs. Built in collaboration with LayerZero, secured by a decentralized DVN set including Canary Protocol, and live via Stargate, the Ondo Bridge enables: → Cross-chain transfers of Ondo tokenized stocks and ETFs with 1:1 asset parity → Thousands of apps on Ethereum and BNB Chain to easily add support for Ondo assets → Rapid expansion to additional EVM chains at scale Onchain securities, now cross-chain.show more

🎉We are excited to announce the first stable #RustyKaspa... (RK) node Release (version 0.14.1). Read: This is a significant milestone for the Kaspa network, as it marks the point where we shift to a new improved and optimized engine, which can now be built upon and accelerated to its limits. "Approx. 2 years ago, when I first proposed the Rust Rewrite, I dreamed of unleashed performance and superb code quality. Today I can say that the new codebase is of the highest quality possible and that the set of individuals contributing to it is now an elite group of people, forming a decentralized and world-spread core development force." - Michael Sutton #L1 #ProofofWork #1BPS for now. #10BPS coming. 🔊SOUND ON!show more

Why Mobile Wallet Protocol? Warpcast uses Mobile Wallet Protocol... to connect frames to a user's wallet on mobile devices. MWP is an open standard with great UX on mobile. Specifically: 1. It works 100% of the time. 2. It's fast. 3. It redirects you between apps smoothly See it in action with the Storage Fairy below. MWP was created by the Coinbase Wallet team and is an open protocol that can work with any wallet. Link in the next tweet. It's really well designed and can work with any wallet. If you're a wallet thinking of supporting MWP, reach out to us! Why not Wallet Connect? WalletConnect works great on desktop and we use it in Warpcast. But on mobile, we ran into several issues that led to bad UX or outright failures. We've shared feedback with the WC team and other wallets about the challenges we've faced and people are working on improving the experience.show more

#CAW Just as the inscriptions on ancient stone monuments... and clay tablets have withstood the test of time, passing down their messages to future generations despite erosion, data recorded on the blockchain remains permanent and unalterable. Just as humanity once engraved history onto physical stone, the blockchain leaves an immutable footprint in the digital world, ensuring that information is preserved and passed on to future generations. The $CAW protocol will empower people with freedom of speech through P2P communication as an on-chain social media platform.show more

The Velas website is undergoing an upgrade to become... the ultimate showcase of the decentralized ecosystem we aspire to become in the future. For the developers out there, #Velas has introduced a cutting-edge fusion of #Solana (eBPF) VM and #Ethereum VM, offering a full hybrid experience. If you're building your #dApp in #Solidity, say hello to lightning-fast speed by utilizing the world's fastest #EVM chain: #Building #Web3show more

Smt Nirmala Sitharaman visits the 2-metre Himalayan Chandra Telescope... (HCT) at the Indian Astronomical Observatory in Hanle, Ladakh. The HCT, an advanced optical-infrared telescope, is remotely operated through a dedicated satellite link from the Centre for Research and Education in Science and Technology (CREST), Indian Institute of Astrophysics (IIA), Hosakote - about 35 km from Bengaluru, Karnataka. Dedicated to the nation on 29 August 2001, the HCT continues to play a vital role in India’s astronomical research and discovery.show more

Artificial embryo samples aboard Tiangong Space Station for life... science research Space "artificial embryo" samples and other life science experiments delivered by the Tianzhou-10 cargo spacecraft have been installed into experiment modules aboard China's Tiangong space station, the Technology and Engineering Center for Space Utilization under the Chinese Academy of Sciences (CAS) said on Wednesday. The "artificial embryos" are stem cell-derived artificial human embryos. The embryos, though not true life forms and unable to develop into human babies, will help simulate the earliest stages of human development. Once the experiments are completed, the artificial embryo samples will be frozen in orbit and then returned to Earth on a future mission for side-by-side analysis with ground-based controls in laboratories on the ground. This effort is part of a broader suite of 41 space science experiments being deployed aboard Tiangong, supporting its latest round of research on the orbiting laboratory.show more