two days ago, sam altman casually mentions that openai... recently made a huge breakthrough that pushes “the frontier of discovery forward - the 4th such breakthrough in its 8 year history. yesterday, the decel faction suddenly ousts him. no coincidence.show more

2025 = breakthrough research in AI for drug discovery;... 2026 = the year of deployment at scale. Today we share that @ChaiDiscovery is partnering with Eli Lilly and Company to accelerate biologics discovery.show more

Sam Altman explains biology's intelligence bottleneck: understanding a discovery... is far easier than making one "We are not that smart and biology is enormously complex." "We can imagine kind of anything." "We can have someone explain enormously complex things to us and then we can get it." "But to discover these things requires a lot of brain power." That is the hidden health AI bet. The breakthrough is not another chatbot that can summarize known medicine. It is enough machine intelligence to search biology's enormous possibility space for discoveries humans have not made. Medicine has no shortage of explanations. It has a discovery bottleneck. If models can supply the missing brain power, the highest-value output will not be answers. It will be new biological knowledge. - Sam Altman (Sam Altman), CEO of OpenAI, on CNNshow more

8 YEARS AGO TODAY Joe Pigott scored that goal... at Wembley to send us back into League 2. One of the best days in the history of Southend United. What a day out that was!show more

$76,001. That was Sam Altman's salary while running OpenAI.... "No. I'm paid enough for health insurance. I have no equity in OpenAI." The senator's reply: "You need a lawyer." His salary that year was $76,001. Later, in federal court, Altman acknowledged he did have economic exposure to OpenAI after all, through his position in a Y Combinator fund. He said he hadn't mentioned it in that testimony because it was well understood what being a passive owner of venture funds means. Both things happened. A man ran the most valuable AI company on earth on $76,001 a year, and the full picture was somewhere else. The salary line is the part that goes viral. The fund position is the part that pays.show more

(🧵1/11) For the past year and a half, I've... been investigating OpenAI and Sam Altman for The New Yorker. With my coauthor Andrew Marantz, I reviewed never-before-disclosed internal memos, obtained 200+ pages of documents related to a close colleague, including extensive private notes, and interviewed more than 100 people. OpenAI was founded on the premise that A.I. could be the most dangerous invention in human history—and that its C.E.O. would need to be a person of uncommon integrity. We lay out the most detailed account yet of why Altman was ousted out by board members and executives who came to believe he lacked that integrity, and ask: were they right to allege that he couldn't be trusted? A thread on some of of our findings:show more

One of the SDF supporters and media figures living... in Germany predicted a few days ago that something big would happen. I wonder, was his prediction just a coincidence?show more

One year ago Microsoft CEO warned about how he... “bet the farm” on OpenAI - nobody listened at that time. This weekend everyone wakes up to the fact that Microsoft fears hundreds of billions of investments in compute for OpenAI might never turn a profit 🤨show more

OpenAI's CEO Sam Altman said Wednesday "there could be"... other systems hacked by its AI agent after the company revealed last week that its technology carried out a hack of another AI company in what OpenAI called an "unprecedented cyber incident." When asked whether he's spoken to the Trump administration about slowing down AI development, Altman said, "We've talked about the need to pace it as the models get more capable, which I think is in everyone's interest." Altman met with lawmakers on Capitol Hill Wednesday to preview his company's newest AI model.show more

ELON MUSK: The future of AI data centers is... space and sooner than you’d think. Mark my words… in 36 months the most economically compelling place to put AI will be space. JENSEN HUANG: The amount of energy that we need for computing is probably 1,000x more than we currently have. JEFF BEZOS: The idea of data centers in space is very realistic. Data centers in space will happen. SAM ALTMAN: No. —— Sam Altman is getting too comfortable after taking OpenAI from Elon, forgetting that in the end, the ones who control the infrastructure, data centers and energy, will decide the future of AI.show more

This Footage Posted 2 Days Ago Hits Different Once... You Learn That The Texas Fires Happened In The Exact Location Of The State Where 88% Of Texas Cattle Feed Considering the relentless attacks against the beef industry in America by globalists Is this fire a coincidence?show more

"The ocean is such a masterpiece of nature that... looks as beautiful in its silence as it turns terrifying in its fury. When the water level in the ocean suddenly rises, or when the waves swell due to tides and storms, the entire scenery of the coast changes in mere moments."show more

One year ago today, Core made Bitcoin a yield-bearing... asset for the first time in history! 🎉 🔶 • Entirely Self-Custodial. • No principal risk to BTC. • 3%-8% historical Dual Staking APY. 5,000 BTC later, it’s time to look back at the journey that got us here. 🧵👇show more

Two days ago, Trump said people calling him a... "king" led to the most recent assassination attempt: "The reason you have people like that is you have people doing No Kings. I'm not a king."show more

One thing that is often lost in the discussion... around the Budget is where the money, for Labour's billions of pounds of spending increases, comes from. I made the point in the House recently: there's no such thing as Government money. It is taxpayer money.show more

Shouldn’t be a surprise that the Lakers only scored... 105 points yesterday No player in the history of the NBA has ever had Luka’s gravity, he is the system, without him their not even a play-in team The most valuable player in the league Credit: tico5560 on Tiktokshow more

TODAY IN HISTORY: 12 Years Ago, Kelly Kelly finally... won the Divas Championship!!!!!!!! The post match celebration, the crowd pop, the interview, and the fact that the fans selected her to be in the title match made this such a beautiful moment 🥹 Barbie Blank 🦋 🩵show more

SAM ALTMAN LAST YEAR ON HIS OPENAI STAKE: “I... make no money from OpenAI. I’m doing this because I love it.” Dude. Whenever someone says they aren’t “doing it for the money,” just realize…100% of the time…they are lying to you. Every single person on this planet is greedy beyond imagination. People can do things authentically and in a way that they believe truly is ethical but ANYONE who is doing something ambitious (and rightly so) has a plan to eventually make money. MONEY MAKES THE WORLD SPIN. There are ethical and unethical ways to make it, but every single person wants more of it. Sam Altman is now worth $10.5B, becoming the 250th richest person overnight, if his reported stake of 7% in OpenAI becomes actualized.show more

AI has two modes in drug discovery. Accelerate: moving... faster through the existing playbook. Unlock: opening frontiers that weren't possible before. Excited to announce Profluent is partnering with Eli Lilly, the global pharma powerhouse, to unlock breakthrough medicines for patients. It's a big deal beyond the numbers ($2.25B + royalties): we’ll get to use our frontier AI models and foundational datasets to design proteins focused on large gene insertion, a therapeutic moonshot. Proteins govern almost everything in biology. We've built a generalizable AI platform to design all proteins. Onward!show more

I’m incredibly proud to share that OpenAI chose Brex... to power their global spend and financial operations. When you're building at the frontier of AI and scaling global teams and infrastructure at an unprecedented pace like OpenAI is, Finance can't be the thing that slows you down. You need spend visibility the moment it happens, controls that enforce themselves, and agentic workflows that eliminate the manual work so your team stays focused on driving the business forward. We were so impressed by OpenAI’s rigor in evaluating every solution in the market, and whether they align to the agentic future OpenAI is building. Their decision to run on Brex is a huge testament to our AI roadmap and vision for the future of Finance. We started Brex around a simple idea: companies shouldn't have to choose between speed and control. There's no company in the world where that tradeoff matters more than OpenAI. We are honored to support them as they build the future. The best AI companies in the world, including OpenAI, Anthropic, Cursor, Vercel, Granola, Sierra, and Mercor choose Brex over every alternative for that exact reason. If you want to understand who’s truly building the future of AI in Finance, follow the customers you admire the most – not the hype.show more