#cryoem

Anya Rossi

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Want to know what happens when mitochondria get stressed? Check our latest pre-print with Simone Mattei lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast! #teamtomo #cryoEM #ribosomes #mitochondria

Want to know what happens when mitochondria get stressed? Check our latest pre-print with Simone Mattei lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast! #teamtomo #cryoEM #ribosomes #mitochondria

135,051 görüntüleme • 3 yıl önce

Our new paper about the structural mechanism by which RAD51 assembles at double-stranded DNA break sites on chromatin has been published in Nature! #CryoEM #Nucleosome #RAD51 #DNArepair

Our new paper about the structural mechanism by which RAD51 assembles at double-stranded DNA break sites on chromatin has been published in Nature! #CryoEM #Nucleosome #RAD51 #DNArepair

72,862 görüntüleme • 2 yıl önce

Excited to share an amazing video on the NLRP3 inflammasome pathway generated by talented Ann from the Iwasa lab Janet Iwasa Ann (Hui Liu). It shows the real cryo-EM structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. #cryoem Le Xiao Enjoy

Excited to share an amazing video on the NLRP3 inflammasome pathway generated by talented Ann from the Iwasa lab Janet Iwasa Ann (Hui Liu). It shows the real cryo-EM structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. #cryoem Le Xiao Enjoy

19,336 görüntüleme • 7 ay önce

I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of Johan Neyts 💊 Published today in Nature: A huge congrats to everyone involved! 🎉

I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of Johan Neyts 💊 Published today in Nature: A huge congrats to everyone involved! 🎉

21,379 görüntüleme • 1 yıl önce

Our new cryo-EM structure explains how the MRN complex can act both as DNA double-strand break sensor & DNA tethering device, read the paper here: Huge thanks to all collaboration partners W.Roos, B.Steigenberger and C. Junge! #cryoEM, #DNArepair, #MRN

Our new cryo-EM structure explains how the MRN complex can act both as DNA double-strand break sensor & DNA tethering device, read the paper here: Huge thanks to all collaboration partners W.Roos, B.Steigenberger and C. Junge! #cryoEM, #DNArepair, #MRN

38,216 görüntüleme • 3 yıl önce

Structural insights into actin isoforms #CryoEM

Structural insights into actin isoforms #CryoEM

eLife - the journal

30,434 görüntüleme • 3 yıl önce

This week, we released a groundbreaking 160 entries from time-resolved #CryoEM capturing G protein activation by a #GPCR. It’s the largest data set from a single publication and describes the order of events driving G protein activation upon GTP binding!

This week, we released a groundbreaking 160 entries from time-resolved #CryoEM capturing G protein activation by a #GPCR. It’s the largest data set from a single publication and describes the order of events driving G protein activation upon GTP binding!

EMDB - EMPIAR @EBI

22,394 görüntüleme • 2 yıl önce

Our #RNA multimer paper out now in nature! #cryoEM of 2 distinct nanocages GOLLD and ROOL and membrane-associated OLE. Multimers at ultra-low concentrations, special covariance for cross-molecule kissing loops, and speculation on function 1/2

Our #RNA multimer paper out now in nature! #cryoEM of 2 distinct nanocages GOLLD and ROOL and membrane-associated OLE. Multimers at ultra-low concentrations, special covariance for cross-molecule kissing loops, and speculation on function 1/2

14,074 görüntüleme • 1 yıl önce

Fresh out of the oven, our collaboration with the Kopito Lab - UFL1(E3) modifies, binds to, and dissociates the 60S subunit from the Sec61 translocon! #ribosome #cryoEM

Fresh out of the oven, our collaboration with the Kopito Lab - UFL1(E3) modifies, binds to, and dissociates the 60S subunit from the Sec61 translocon! #ribosome #cryoEM

18,849 görüntüleme • 2 yıl önce

(2/3) Very decent resolution locally up to 2.5 A from inside of human cells (we hit Nyquist). Aquilos FIB-milling. Fully tomographic workflow. Subtomogram averaging. #CryoEM #teamtomo Max Planck Institute of Biophysics

(2/3) Very decent resolution locally up to 2.5 A from inside of human cells (we hit Nyquist). Aquilos FIB-milling. Fully tomographic workflow. Subtomogram averaging. #CryoEM #teamtomo Max Planck Institute of Biophysics

Beck Laboratory

19,440 görüntüleme • 3 yıl önce

Excited to share our new preprint on co-transcriptional splicing! U1 snRNP is recruited to RNA polymerase II through multiple interaction sites, with elongation factor SPT6 binding directly to the U1 snRNP protein. #cryoEM #transcription #splicing

Excited to share our new preprint on co-transcriptional splicing! U1 snRNP is recruited to RNA polymerase II through multiple interaction sites, with elongation factor SPT6 binding directly to the U1 snRNP protein. #cryoEM #transcription #splicing

10,458 görüntüleme • 1 yıl önce

Guillermo Montoya's group at UCPH Healthscience expands the understanding of the #CRISPR-associated #transposon systems (CAST) RNA-guided integration Molecular Cell👇 The study shows variants enhancing the integration activity of V-K CASTs #genomeediting #CryoEM

Guillermo Montoya's group at UCPH Healthscience expands the understanding of the #CRISPR-associated #transposon systems (CAST) RNA-guided integration Molecular Cell👇 The study shows variants enhancing the integration activity of V-K CASTs #genomeediting #CryoEM

12,303 görüntüleme • 2 yıl önce