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A daily multivitamin can reduce brain aging and modestly slow down epigenetic aging clocks. In the COSMOS trial, older adults who took a standard Centrum Silver multivitamin daily for about 4 years performed better on cognitive tests and showed the equivalent of ~2 years less brain aging compared with...

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Dr. Rhonda Patrick

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56,738 views • 2 months ago •via X (Twitter)

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For older adults, a daily multivitamin is a high-priority basic, not an optional supplement Across three COSMOS cognitive studies of adults 65+, a standard multivitamin (Centrum Silver) slowed global brain aging by about 2 years The biggest effect showed up in episodic memory (remembering experiences, names, faces, and events), which aged almost 5 years slower A related COSMOS analysis also found modest slowing in biological aging clocks, making this one of the lowest-effort ways to cover micronutrient gaps as the brain ages
4:41

For older adults, a daily multivitamin is a high-priority basic, not an optional supplement Across three COSMOS cognitive studies of adults 65+, a standard multivitamin (Centrum Silver) slowed global brain aging by about 2 years The biggest effect showed up in episodic memory (remembering experiences, names, faces, and events), which aged almost 5 years slower A related COSMOS analysis also found modest slowing in biological aging clocks, making this one of the lowest-effort ways to cover micronutrient gaps as the brain ages

FoundMyFitness Clips

14,221 views • 2 months ago

A run-of-the-mill multivitamin can measurably change how your brain ages In three large randomized controlled trials of older adults (65+), daily Centrum Silver led to about 2 years less brain aging versus placebo Even more striking, episodic memory aging (remembering experiences, people, and events) looked roughly 5 years “younger” in the multivitamin group On top of that, it acts as basic insurance, filling micronutrient gaps that most diets simply don’t cover
2:59

A run-of-the-mill multivitamin can measurably change how your brain ages In three large randomized controlled trials of older adults (65+), daily Centrum Silver led to about 2 years less brain aging versus placebo Even more striking, episodic memory aging (remembering experiences, people, and events) looked roughly 5 years “younger” in the multivitamin group On top of that, it acts as basic insurance, filling micronutrient gaps that most diets simply don’t cover

FoundMyFitness Clips

123,808 views • 5 months ago

For brain health in older adults, a multivitamin is no longer “optional” - it’s a high-priority basic In three large randomized trials of adults 65+, taking a standard multivitamin like Centrum Silver for one year slowed global brain aging by about 2.1 years and episodic memory aging by almost 5 years That means better retention of everyday experiences, names, faces, and events (the things families actually notice when memory starts to fade) Given how common poor diets and micronutrient gaps are, a single daily multivitamin is an easy, low-effort way to protect aging brains
1:30

For brain health in older adults, a multivitamin is no longer “optional” - it’s a high-priority basic In three large randomized trials of adults 65+, taking a standard multivitamin like Centrum Silver for one year slowed global brain aging by about 2.1 years and episodic memory aging by almost 5 years That means better retention of everyday experiences, names, faces, and events (the things families actually notice when memory starts to fade) Given how common poor diets and micronutrient gaps are, a single daily multivitamin is an easy, low-effort way to protect aging brains

FoundMyFitness Clips

94,279 views • 6 months ago

Rhonda Patrick dropped this on Mayim Bialik’s podcast:“As simple as a cheap daily multivitamin… it reversed brain aging by five years.” Three large randomized controlled trials showed that older adults taking a basic affordable multivitamin for a couple of years slowed cognitive aging by about 3 years and reversed episodic memory aging by roughly 5 years. The COSMOS trial and related studies found daily multivitamin use improved memory, executive function, and slowed brain aging in older adults, likely by filling common micronutrient gaps. It’s a reminder that sometimes the simplest things still pack a real punch. In our rush for fancy biohacks and expensive protocols, we often overlook basic, affordable interventions that actually have strong evidence behind them. What about you — do you take a daily multivitamin, or do you rely purely on food?
0:51

Rhonda Patrick dropped this on Mayim Bialik’s podcast:“As simple as a cheap daily multivitamin… it reversed brain aging by five years.” Three large randomized controlled trials showed that older adults taking a basic affordable multivitamin for a couple of years slowed cognitive aging by about 3 years and reversed episodic memory aging by roughly 5 years. The COSMOS trial and related studies found daily multivitamin use improved memory, executive function, and slowed brain aging in older adults, likely by filling common micronutrient gaps. It’s a reminder that sometimes the simplest things still pack a real punch. In our rush for fancy biohacks and expensive protocols, we often overlook basic, affordable interventions that actually have strong evidence behind them. What about you — do you take a daily multivitamin, or do you rely purely on food?

Camus

18,211 views • 3 months ago

Taking a daily multivitamin slowed brain aging by 2 years in older adults. Rhonda Patrick highlighted three large randomized placebo-controlled trials (COSMOS) with ~5,000 participants aged 65+. The group taking a multivitamin (magnesium, B vitamins, folate, vitamin K, etc.) showed clear improvements in cognition and slower brain aging compared to placebo. Simple micronutrients making a measurable difference. What’s your take, would this make you consider adding a high-quality multivitamin to your routine?
0:48

Taking a daily multivitamin slowed brain aging by 2 years in older adults. Rhonda Patrick highlighted three large randomized placebo-controlled trials (COSMOS) with ~5,000 participants aged 65+. The group taking a multivitamin (magnesium, B vitamins, folate, vitamin K, etc.) showed clear improvements in cognition and slower brain aging compared to placebo. Simple micronutrients making a measurable difference. What’s your take, would this make you consider adding a high-quality multivitamin to your routine?

Camus

29,689 views • 1 month ago

Omega-3s may be one of the most powerful dietary tools for resolving inflammation and slowing biological aging In a 3-year randomized trial of healthy older adults, omega-3 alone slowed epigenetic aging, while vitamin D and resistance training alone did not But the biggest effect came when all three were combined: omega-3, vitamin D, and resistance training slowed biological aging by about 3.8 months That may sound small, but it reflects a slower pace of aging that could compound over time The combo was also linked to ~40% lower pre-frailty and 61% lower invasive cancer incidence
2:47

Omega-3s may be one of the most powerful dietary tools for resolving inflammation and slowing biological aging In a 3-year randomized trial of healthy older adults, omega-3 alone slowed epigenetic aging, while vitamin D and resistance training alone did not But the biggest effect came when all three were combined: omega-3, vitamin D, and resistance training slowed biological aging by about 3.8 months That may sound small, but it reflects a slower pace of aging that could compound over time The combo was also linked to ~40% lower pre-frailty and 61% lower invasive cancer incidence

FoundMyFitness Clips

301,576 views • 3 months ago

Supplementing with omega-3 fatty acids slows biological aging. Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging. These were the results of the 3-year-long DO-HEALTH study, which Prof Steve Horvath believes is one of the strongest pieces of evidence that simple interventions (that also likely correct a deficiency) are powerful ways to slow or reverse the aging process. We discuss this study and more in the latest episode of the FoundMyFitness podcast.
5:26

Supplementing with omega-3 fatty acids slows biological aging. Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging. These were the results of the 3-year-long DO-HEALTH study, which Prof Steve Horvath believes is one of the strongest pieces of evidence that simple interventions (that also likely correct a deficiency) are powerful ways to slow or reverse the aging process. We discuss this study and more in the latest episode of the FoundMyFitness podcast.

Dr. Rhonda Patrick

493,715 views • 2 months ago

5 supplements that give you big bang for your buck: • Omega-3 — a high omega-3 index is linked to 5 extra years of life expectancy, 66% lower Alzheimer’s risk, and slower epigenetic aging • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years • Multivitamin — daily use in older adults was linked to 2.1 years less global brain aging, nearly 5 years less episodic memory aging, and modestly slower epigenetic aging • Magnesium — supports 300+ enzymes involved in DNA repair and sleep, and low intake has been linked to higher cancer risk • Creatine monohydrate — one of the most studied supplements for strength and performance, with 10 grams as a baseline for brain benefits
0:40

5 supplements that give you big bang for your buck: • Omega-3 — a high omega-3 index is linked to 5 extra years of life expectancy, 66% lower Alzheimer’s risk, and slower epigenetic aging • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years • Multivitamin — daily use in older adults was linked to 2.1 years less global brain aging, nearly 5 years less episodic memory aging, and modestly slower epigenetic aging • Magnesium — supports 300+ enzymes involved in DNA repair and sleep, and low intake has been linked to higher cancer risk • Creatine monohydrate — one of the most studied supplements for strength and performance, with 10 grams as a baseline for brain benefits

FoundMyFitness Clips

513,930 views • 4 months ago

Consistent endurance exercise may be one of the most powerful ways to slow down biological aging. Six months of cycling (about 4.5 hours/week) reduced GrimAge by 7 months relative to the expected trajectory of normal aging. GrimAge is an epigenetic clock tied to mortality risk. Participants also increased VO₂ max by ~20%, and the reduction in GrimAge tracked with those gains in cardiorespiratory fitness, but not with changes in body composition. The anti-aging signal seemed to come more from becoming fitter, not just leaner. To Prof Steve Horvath, this suggests biological aging is, at least to some extent, modifiable. We discuss how exercise may slow biological aging in the latest episode of the podcast. Out now.
1:01

Consistent endurance exercise may be one of the most powerful ways to slow down biological aging. Six months of cycling (about 4.5 hours/week) reduced GrimAge by 7 months relative to the expected trajectory of normal aging. GrimAge is an epigenetic clock tied to mortality risk. Participants also increased VO₂ max by ~20%, and the reduction in GrimAge tracked with those gains in cardiorespiratory fitness, but not with changes in body composition. The anti-aging signal seemed to come more from becoming fitter, not just leaner. To Prof Steve Horvath, this suggests biological aging is, at least to some extent, modifiable. We discuss how exercise may slow biological aging in the latest episode of the podcast. Out now.

Dr. Rhonda Patrick

81,809 views • 2 months ago

A daily multivitamin could significantly reverse cognitive aging by up to 5 years Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory (the ability to recall experiences and events) Far from being "expensive urine," a multivitamin can actually make your brain functionally younger—restoring memory to levels seen five years earlier
2:11

A daily multivitamin could significantly reverse cognitive aging by up to 5 years Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory (the ability to recall experiences and events) Far from being "expensive urine," a multivitamin can actually make your brain functionally younger—restoring memory to levels seen five years earlier

FoundMyFitness Clips

29,155 views • 11 months ago

Everyone should take a multivitamin. It's a simple, effective way to support long-term cognitive health, especially for middle-aged and older adults. About a decade ago, multivitamins were deemed useless or harmful. Recent large, randomized controlled studies provide irrefutable evidence to the contrary. Adults taking a standard multivitamin for 2 years improved cognition and episodic memory, equivalent to a 2-year reduction in cognitive aging. Multivitamins provide micronutrients missing from our diets—those important for metabolism, neurotransmission, and most importantly, reducing DNA damage and oxidative stress that contribute to aging. Think of it as nutritional insurance for your body and brain. And don't let anyone tell you it's just making "expensive urine."
0:38

Everyone should take a multivitamin. It's a simple, effective way to support long-term cognitive health, especially for middle-aged and older adults. About a decade ago, multivitamins were deemed useless or harmful. Recent large, randomized controlled studies provide irrefutable evidence to the contrary. Adults taking a standard multivitamin for 2 years improved cognition and episodic memory, equivalent to a 2-year reduction in cognitive aging. Multivitamins provide micronutrients missing from our diets—those important for metabolism, neurotransmission, and most importantly, reducing DNA damage and oxidative stress that contribute to aging. Think of it as nutritional insurance for your body and brain. And don't let anyone tell you it's just making "expensive urine."

Dr. Rhonda Patrick

257,107 views • 1 year ago

5 high-impact supplements worth taking daily: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index is linked to 5 extra years of life expectancy, slower epigenetic aging, and may lower Alzheimer’s risk • Multivitamin — daily use in older adults has been linked to ~2 years less global brain aging, nearly 5 years less episodic memory aging • Vitamin D — regulates over 5% of your genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity • Magnesium — a cofactor for 300+ biological processes, including DNA repair, energy production, and sleep regulation • Creatine monohydrate — one of the most studied supplements for strength and performance; 10 g/day is a baseline for brain benefits, with higher-dose research showing benefits under sleep deprivation
1:25

5 high-impact supplements worth taking daily: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index is linked to 5 extra years of life expectancy, slower epigenetic aging, and may lower Alzheimer’s risk • Multivitamin — daily use in older adults has been linked to ~2 years less global brain aging, nearly 5 years less episodic memory aging • Vitamin D — regulates over 5% of your genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity • Magnesium — a cofactor for 300+ biological processes, including DNA repair, energy production, and sleep regulation • Creatine monohydrate — one of the most studied supplements for strength and performance; 10 g/day is a baseline for brain benefits, with higher-dose research showing benefits under sleep deprivation

FoundMyFitness Clips

30,877 views • 1 month ago

Taking a daily multivitamin can reverse cognitive aging by several years Multiple randomized controlled trials found that older adults who took a basic multivitamin (like Centrum Silver) experienced clear improvements in overall cognitive function This included faster processing speed and dramatically enhanced episodic memory (the memory used to recall personal experiences and events) Far from useless, a simple multivitamin could be one of your strongest allies against cognitive decline
2:36

Taking a daily multivitamin can reverse cognitive aging by several years Multiple randomized controlled trials found that older adults who took a basic multivitamin (like Centrum Silver) experienced clear improvements in overall cognitive function This included faster processing speed and dramatically enhanced episodic memory (the memory used to recall personal experiences and events) Far from useless, a simple multivitamin could be one of your strongest allies against cognitive decline

FoundMyFitness Clips

387,068 views • 10 months ago

A daily multivitamin may be one of the lowest-effort ways to make an older brain functionally younger In large randomized trials of older adults (65+), those taking a basic multivitamin (Centrum Silver) showed better overall cognition, about a 2-year reduction in global brain aging, and ~4.8 years' improvement in episodic memory (the ability to remember events and experiences) Given that ~60% of Americans are low in vitamin E, ~45–50% in magnesium, ~35% in vitamin C, and 80–90% in omega-3s (with additional gaps in vitamin K and calcium), it’s clear many brains are running on suboptimal micronutrient status For many, a basic multivitamin is a practical way to close these gaps and protect cognitive function with age
2:44

A daily multivitamin may be one of the lowest-effort ways to make an older brain functionally younger In large randomized trials of older adults (65+), those taking a basic multivitamin (Centrum Silver) showed better overall cognition, about a 2-year reduction in global brain aging, and ~4.8 years' improvement in episodic memory (the ability to remember events and experiences) Given that ~60% of Americans are low in vitamin E, ~45–50% in magnesium, ~35% in vitamin C, and 80–90% in omega-3s (with additional gaps in vitamin K and calcium), it’s clear many brains are running on suboptimal micronutrient status For many, a basic multivitamin is a practical way to close these gaps and protect cognitive function with age

FoundMyFitness Clips

186,671 views • 7 months ago

These are the supplements I give my aging parents: • A daily multivitamin • Vitamin D • High-DHA omega-3s • Ubiquinol (the reduced form of CoQ10) • Sulforaphane Why these? Large RCTs show improved cognition in older adults taking a standard multivitamin, with benefits equivalent to a brain that's 2-5 years younger. For vitamin D, more than 70% of older U.S. adults are insufficient, and aging skin produces far less vitamin D from sunlight (a 70-year-old makes roughly 4x less than their 20-year-old self). DHA is a key structural fat in the brain and supports cognitive function, especially important with aging and neurodegenerative risk, while CoQ10 supports mitochondrial energy production as levels drop with age. Finally, sulforaphane is a powerful activator of Nrf2, the body's master stress-response pathway, up-regulating glutathione and phase II detox enzymes.
12:23

These are the supplements I give my aging parents: • A daily multivitamin • Vitamin D • High-DHA omega-3s • Ubiquinol (the reduced form of CoQ10) • Sulforaphane Why these? Large RCTs show improved cognition in older adults taking a standard multivitamin, with benefits equivalent to a brain that's 2-5 years younger. For vitamin D, more than 70% of older U.S. adults are insufficient, and aging skin produces far less vitamin D from sunlight (a 70-year-old makes roughly 4x less than their 20-year-old self). DHA is a key structural fat in the brain and supports cognitive function, especially important with aging and neurodegenerative risk, while CoQ10 supports mitochondrial energy production as levels drop with age. Finally, sulforaphane is a powerful activator of Nrf2, the body's master stress-response pathway, up-regulating glutathione and phase II detox enzymes.

Dr. Rhonda Patrick

217,153 views • 8 months ago

Major weight loss clearly and strongly slows biological aging In an analysis of a 32-week GLP-1 agonist (semaglutide) trial in adults with excess visceral fat, multiple epigenetic aging clocks picked up the improvement The likely mechanism: less visceral fat means less adipose-driven inflammatory and metabolic signaling that can accelerate aging biology That fits a hard truth about obesity: it actively pushes aging biology in the wrong direction, raising risk for cardiovascular disease, type 2 diabetes, cancer, and shorter life expectancy
2:11

Major weight loss clearly and strongly slows biological aging In an analysis of a 32-week GLP-1 agonist (semaglutide) trial in adults with excess visceral fat, multiple epigenetic aging clocks picked up the improvement The likely mechanism: less visceral fat means less adipose-driven inflammatory and metabolic signaling that can accelerate aging biology That fits a hard truth about obesity: it actively pushes aging biology in the wrong direction, raising risk for cardiovascular disease, type 2 diabetes, cancer, and shorter life expectancy

FoundMyFitness Clips

111,440 views • 2 months ago

4 supplements that give you the biggest bang for your buck: • Multivitamin — 3 large RCTs show it reduces brain aging by ~2 years and reverses episodic memory aging by ~5 years in older adults • Omega-3s — a high omega-3 index (8%+) is linked to 5 years of increased life expectancy and 90% lower risk of sudden cardiac death • Magnesium — a cofactor for 300+ biological processes including DNA repair and energy production; 60%+ of the US population is deficient • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years
1:08

4 supplements that give you the biggest bang for your buck: • Multivitamin — 3 large RCTs show it reduces brain aging by ~2 years and reverses episodic memory aging by ~5 years in older adults • Omega-3s — a high omega-3 index (8%+) is linked to 5 years of increased life expectancy and 90% lower risk of sudden cardiac death • Magnesium — a cofactor for 300+ biological processes including DNA repair and energy production; 60%+ of the US population is deficient • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years

FoundMyFitness Clips

145,571 views • 5 months ago

Coffee may be the most overlooked anti-aging tool hiding in plain sight Emerging research reveals that coffee can actively slow biological aging—each daily cup consumed correlates with a 0.7–1 year reduction in epigenetic age Drinking 3+ cups daily reduces the risk of accelerated aging by 34–41% and lowers death risk from all causes (compared to non-coffee drinkers) by 27%, translating to nearly two extra years of life Even decaf delivers similar powerful benefits The takeaway is clear: Regular coffee drinkers consistently live longer
1:19

Coffee may be the most overlooked anti-aging tool hiding in plain sight Emerging research reveals that coffee can actively slow biological aging—each daily cup consumed correlates with a 0.7–1 year reduction in epigenetic age Drinking 3+ cups daily reduces the risk of accelerated aging by 34–41% and lowers death risk from all causes (compared to non-coffee drinkers) by 27%, translating to nearly two extra years of life Even decaf delivers similar powerful benefits The takeaway is clear: Regular coffee drinkers consistently live longer

FoundMyFitness Clips

766,886 views • 1 year ago

New episode with Dr. Steve Horvath (Prof Steve Horvath), a pioneer in the field of epigenetic aging clocks. Steve developed the original Horvath clock, one of the first tools to show that DNA methylation carries a remarkably reliable signal of aging across human tissues. In this episode, he explains what biological clocks actually measure, why different clocks can disagree, and how to interpret a biological-age result without treating it like a literal lifespan forecast. We talk about chronological age vs. biological age, and we also get into the intervention evidence on exercise and VO2 max, calorie restriction, omega-3s, vitamin D, multivitamins, and weight loss/GLP-1 therapy, among other topics! The big theme is that biological clocks can be useful dashboards, but they are not diagnoses, fortune-telling tools, or proof that one supplement has reversed aging. This was Steve's second appearance on the podcast and he did not disappoint. You won't want to miss this episode. Links to the episode on all platforms in the comments below. Timestamps: 0:00 - Introduction 1:59 - Biological vs. chronological age 7:33 - Why one clock isn't enough 13:16 - PhenoAge vs. GrimAge 15:21 - GrimAge & mortality risk 19:04 - Epigenome as stress memory 23:02 - Can stress be inherited? 25:06 - Why clocks fail in sperm 26:30 - Can lifestyle reverse GrimAge? 28:18 - DunedinPACE as an odometer 32:20 - Judging longevity interventions 34:41 - Clocks as mortality surrogates 38:28 - Most validated interventions 41:25 - 5 years younger in 7 months? 45:43 - Can GrimAge predict death? 47:30 - Translating GrimAge to lifespan 52:16 - Blind spots of aging clocks 58:20 - More than inflammation 1:00:56 - Young blood, transient effects 1:04:46 - Calorie restriction 1:08:54 - GLP-1 drugs & weight loss 1:12:24 - Can a multivitamin slow aging? 1:21:05 - Omega-3, vitamin D, & exercise 1:28:55 - Removing an aging accelerator 1:31:24 - Vegetables vs. exercise 1:36:58 - Does red meat age you? 1:38:38 - Hard training moves the clock 1:45:59 - Heat as an exercise mimetic 1:47:23 - When cold slows the clock 1:49:48 - Does poor sleep speed aging? 1:51:19 - Can friendship slow aging? 1:57:49 - Are consumer tests worth it? 2:02:46 - Choosing a reliable test 2:07:33 - Different clocks, different lenses 2:12:21 - Can AI build better clocks? 2:13:53 - Partial reprogramming 2:17:47 - What reprogramming can't fix 2:22:37 - Do DNA mutations drive aging? 2:24:53 - The silver bullet problem 2:29:23 - Limits of polygenic risk 2:33:32 - Steve's longevity routine 2:38:05 - How stress affects aging
2:39:14

New episode with Dr. Steve Horvath (Prof Steve Horvath), a pioneer in the field of epigenetic aging clocks. Steve developed the original Horvath clock, one of the first tools to show that DNA methylation carries a remarkably reliable signal of aging across human tissues. In this episode, he explains what biological clocks actually measure, why different clocks can disagree, and how to interpret a biological-age result without treating it like a literal lifespan forecast. We talk about chronological age vs. biological age, and we also get into the intervention evidence on exercise and VO2 max, calorie restriction, omega-3s, vitamin D, multivitamins, and weight loss/GLP-1 therapy, among other topics! The big theme is that biological clocks can be useful dashboards, but they are not diagnoses, fortune-telling tools, or proof that one supplement has reversed aging. This was Steve's second appearance on the podcast and he did not disappoint. You won't want to miss this episode. Links to the episode on all platforms in the comments below. Timestamps: 0:00 - Introduction 1:59 - Biological vs. chronological age 7:33 - Why one clock isn't enough 13:16 - PhenoAge vs. GrimAge 15:21 - GrimAge & mortality risk 19:04 - Epigenome as stress memory 23:02 - Can stress be inherited? 25:06 - Why clocks fail in sperm 26:30 - Can lifestyle reverse GrimAge? 28:18 - DunedinPACE as an odometer 32:20 - Judging longevity interventions 34:41 - Clocks as mortality surrogates 38:28 - Most validated interventions 41:25 - 5 years younger in 7 months? 45:43 - Can GrimAge predict death? 47:30 - Translating GrimAge to lifespan 52:16 - Blind spots of aging clocks 58:20 - More than inflammation 1:00:56 - Young blood, transient effects 1:04:46 - Calorie restriction 1:08:54 - GLP-1 drugs & weight loss 1:12:24 - Can a multivitamin slow aging? 1:21:05 - Omega-3, vitamin D, & exercise 1:28:55 - Removing an aging accelerator 1:31:24 - Vegetables vs. exercise 1:36:58 - Does red meat age you? 1:38:38 - Hard training moves the clock 1:45:59 - Heat as an exercise mimetic 1:47:23 - When cold slows the clock 1:49:48 - Does poor sleep speed aging? 1:51:19 - Can friendship slow aging? 1:57:49 - Are consumer tests worth it? 2:02:46 - Choosing a reliable test 2:07:33 - Different clocks, different lenses 2:12:21 - Can AI build better clocks? 2:13:53 - Partial reprogramming 2:17:47 - What reprogramming can't fix 2:22:37 - Do DNA mutations drive aging? 2:24:53 - The silver bullet problem 2:29:23 - Limits of polygenic risk 2:33:32 - Steve's longevity routine 2:38:05 - How stress affects aging

Dr. Rhonda Patrick

86,945 views • 2 months ago