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A potentially high-efficiency alternative to making large genome edits: making large RNA edits via splicing! Very cool proof-of-concept from Jacob Borrajo Kamyab Javanmardi, Ph.D. ⚛️ Basem Al-Shayeb, Ph.D. 🧬 & Blainey Lab in bioRxiv

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Julia Bauman

10,421 subscribers

15,348 Aufrufe • vor 2 Jahren •via X (Twitter)

Wissenschaft & Technologie
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Profilbild von Julia Bauman
Julia Baumanvor 2 Jahren

Find the preprint here:

Profilbild von Ahmed Mahfouz
Ahmed Mahfouzvor 2 Jahren

@jacobborrajo @Kamyab_J @themicrobeguy @BlaineyLab @biorxivpreprint This looks intersting @oligogirl @PSpitali

Profilbild von Danny Diaz
Danny Diazvor 2 Jahren

@jacobborrajo @Kamyab_J @themicrobeguy @BlaineyLab @biorxivpreprint @DrJimmyDale check out Kamyab latest work. #grinding

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"Transcription factors allow a very small number of base pair edits at the substrate of the genome to lead to very large phenotypic differences. If you think about how attention works - queries, keys, values - transcription factors are the queries, the genome sequences they bind to are the keys, and genes are the values." Full episode w Jacob Kimmel out tomorrow.

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