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Andrew Huberman drops a nuanced truth bomb on nicotine in this 34-second clip: “Nicotine is neuroprotective… increases acetylcholine and dopamine and epinephrine, leads to heightened focus, improved memory, and can offset neurodegeneration in Parkinson’s and Alzheimer’s.” But he immediately shuts down any misinterpretation: “Smoking cigarettes is bad because it’s... show more
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![REPORT: Theo Von asked Dr. McCullough if anyone was “immune” to COVID, and his answer caught almost everyone off guard. THEO VON: “Was there anybody who was immune to COVID-19?” DR. MCCULLOUGH: “There’s one adult group. You’re going to laugh.” [Theo Von listens closely for the reveal] DR. MCCULLOUGH: “Smokers… They got very mild cases. And they don’t get long COVID.” THEO VON: “Why?” MCCULLOUGH: “Because smokers maintain a level of nicotine in the bloodstream… Smoking blocks the spike protein. It’s amazing. I thought smokers were going to go down.” THEO VON: “Do you think that’s a good idea [to use nicotine patches] on a regular basis?” DR. MCCULLOUGH: “I think [it’s a good idea] if they have long COVID... Nicotine, don’t forget, is a nootropic. A nootropic is a drug that makes the brain function more effectively... It’s addictive, but it’s not harmful to the human body... Nicotine patches are perfectly safe.” The clip quickly went viral, racking up more than 4 million views on X alone. To be clear, Dr. McCullough is not encouraging anyone to start smoking. His point is that nicotine itself is not the primary source of tobacco’s health risks. Rather, he argues that tar and other toxic substances in tobacco smoke are responsible for much of the damage. “Nicotine patches are perfectly safe,” he says. Epidemiologist Nicolas Hulscher, MPH quote-tweeted the post with additional context that backs up Dr. McCullough’s claims. He wrote: “A recent study found nicotine patches fully RESOLVED long COVID symptoms in some patients within DAYS. Spike protein hijacks nicotinic acetylcholine receptors. Nicotine blocks spike from binding to them, restoring normal signaling. This likely also applies to long VACCINE.”](https://image.24vids.com/tw-2062324794524086328/amplify_video_thumb/2062323902731218944/img/f5WHFQxSH2J6GSoL.jpg)
![THEO VON: “Was there anybody who was immune to COVID-19?” DR. MCCULLOUGH: “There’s one adult group. You’re going to laugh.” [Theo Von listens closely for the reveal] DR. MCCULLOUGH: “Smokers… They got very mild cases. And they don’t get long COVID.” THEO VON: “Why?” MCCULLOUGH: “Because smokers maintain a level of nicotine in the bloodstream… Smoking blocks the spike protein. It’s amazing. I thought smokers were going to go down.” THEO VON: “Do you think that’s a good idea [to use nicotine patches] on a regular basis?” DR. MCCULLOUGH: “I think [it’s a good idea] if they have long COVID... Nicotine, don’t forget, is a nootropic. A nootropic is a drug that makes the brain function more effectively... It’s addictive, but it’s not harmful to the human body... Nicotine patches are perfectly safe.”](https://image.24vids.com/tw-2061815682786808185/amplify_video_thumb/2061815437197815808/img/o2QD0Vpur8wATNzR.jpg)
![If common social media features like recommendation algorithms and "Like" buttons are truly addictive, as a LA court found last week, it's impossible to make sense of OpenAI shuttering Sora. "Sora was basically the same as TikTok, Instagram Reels, YouTube Shorts, and Snap in terms of UI and UX design." "It had infinite scroll, algorithmic recommendations, notifications, a 'Like' button. It didn't have IG beauty features, but like, the whole thing was a filter. I could go in there and say, 'Make me look like a bodybuilder,' and it did a good job, and I looked great in the videos. It really checks all of the same boxes." "There's a bunch of comparisons to the cigarette industry...It's the nicotine [that's addictive], and that's why you have like 50 different cigarette brands, and 1,000 different e-cigarette brands. And nicotine gum, nicotine patches, and nicotine pouches are addictive — because they all contain the nicotine." "If the court is asking us to believe that the 'Like' button, the algorithmic feed, that [those are] addictive, then we should see addiction-like results from any app that implements that." "That is the case for all nicotine-containing products — they all addict people."](https://image.24vids.com/tw-2038715986669674734/amplify_video_thumb/2038715545567326208/img/fr6AQi9B3eJcG34G.jpg)
![I think about this twice a day. Every morning when I sit down to read & then when I sit down to write, I say to myself, "Accept the initial agitation." When you try to focus, Andrew Huberman explains, "the brain circuits that turn on first are of the stress system." Meaning: "The agitation and stress that you feel at the beginning of something—when you're trying to lean into it and you can't focus—is just a recognized gate. You have to pass through that gate to get to the focus component." There's a common misconception, Huberman continues, "The misunderstanding around how certain brain circuits work has led to this idea that there's some secret entry point—maybe marked 'flow' on the door—and there's a trampoline up to that door, and you just open that door, and you're immediately in [a deep state of focus]. And nothing could be further from the truth." The truth is: "There is a gate of entry. You have to wade through some sewage before you can swim in clear water. That's the way I always think about it." I once told Andrew that I say to myself, "accept the initial agitation," every time I sit down to read or write, and he said, "the agitation is indeed the doorway to the whole process." - - - The clip below is from Andrew's 2020 interview on Rich Roll's podcast (](https://image.24vids.com/tw-1734688163552260192/amplify_video_thumb/1734687902729195520/img/Ijq6WIeyPvuDQa7t.jpg)
