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Andrew Huberman spent years studying intermittent fasting. He just broke down what's quietly wrecking people's fasting results. Here are 10 things he revealed (THREAD): 1. Late night eating ruins your liver's repair window

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David Sinclair has spent decades at Harvard studying how to slow and reverse aging. He revealed 10 things you can start doing today to actually live longer (THREAD): 1) Fasting turns on your longevity genes
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Andrew Huberman's no-BS weight loss advice: "If you're overweight, don't overcomplicate it—just shrink your eating window." His patient needed to drop pounds. Huberman: "Start eating at 2 PM, cut off at 10 PM. Eat whatever you want inside that—ideally meats, veggies, minimal sugar, no alcohol." Result? 60 pounds gone—and kept off for 2 years. "I'm an omnivore—I love meat and butter." No dogma, just results. Intermittent fasting + quality foods = simple, sustainable fat loss. Watch this straightforward clip. Struggled with weight? Tried time-restricted eating? What's your window and results? Share below.

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Intermittent fasting protocol, benefits & myths: - Around 11-12 hours of fasting depletes liver glycogen, forcing the body to shift from burning carbohydrates to burning fat and producing ketone bodies. - Ketones are a cleaner fuel source. They generate less oxidative stress and require less energy to metabolize than glucose. - Ketones activate BDNF, supporting learning, memory, and neuroplasticity, while also increasing GABA to quiet mental noise and sharpen focus. - A 5:2 fasting protocol (500 calories on 2 days per week, normal eating the other 5) produced a 20% improvement in cognitive test scores compared to simple caloric restriction alone. - Early time-restricted eating (stopping food intake by 6-8 p.m.) produced a ~10 mmHg drop in blood pressure, comparable in magnitude to first-line hypertension medications. - Fasting doesn't cause muscle loss if paired with resistance training, prioritizing protein within the eating window is enough to preserve lean mass. Dr. Rhonda Patrick on Andrew D. Huberman, Ph.D.

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Struggling with stubborn belly fat that won't budge? Renowned cardiologist Dr. Pradip Jamnadas, with over 30 years of experience helping patients improve heart health and metabolism, shares his practical step-by-step approach to intermittent fasting in this insightful 58-second clip. He explains how to gradually build fasting habits: - Start gently: A 12-hour fasting window (e.g., stop eating at 8 PM, eat again at 8 AM) with no-calorie drinks only—do this for 2-3 weeks to ease in. - Progress: Move to 18-6 (18 hours fasting, 6-hour eating window) using water, black coffee/tea, or green tea. - For bigger goals (like significant weight loss or supporting metabolic health): Incorporate a 48-hour fast weekly, or every 9-10 days combine OMAD (One Meal A Day) with a 3-day water fast. Dr. Jamnadas emphasizes starting slow and listening to your body—many find it boosts energy over time! Important: This is general educational info. Always consult your healthcare professional before trying fasting, especially if you have conditions like diabetes or are on medications. What's one small change you've made for better health lately?
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You can lose 50+ pounds (22+ kg) without changing what you eat — just by changing when you eat. Intermittent fasting (IF) is blowing up because it works: - 16:8 (eat noon–8pm, fast 16 hrs) - 5:2 (eat normally 5 days, fast or 500 cal the other 2) - Even a simple 12-hour eating window Sumaya Kazi lost 50 pounds (22 kg) doing 36-hour fasts 3 days a week. She says the first 2 weeks were brutal (hungry as hell), but then: mental clarity, steady energy, no more lethargy after meals, and the weight melted off. Experts on the panel: - It improves insulin sensitivity, lowers blood pressure, triggers cellular repair/autophagy - Metabolism actually speeds up (up to 10% in studies) — the “starvation mode” fear is a myth (takes 72+ hours to slow) - Best results when eating window overlaps morning (when digestion enzymes are optimized) The biggest win? You don’t have to obsess over calories or food rules on eat days — just stay consistent with the window. Have you tried intermittent fasting yet? What window worked (or didn’t) for you — 16:8, 18:6, 5:2, or something else? Your results / questions 👇
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You can lose 50+ pounds (22+ kg) without changing what you eat — just by changing when you eat. Intermittent fasting (IF) is blowing up because it works: - 16:8 (eat noon–8pm, fast 16 hrs) - 5:2 (eat normally 5 days, fast or 500 cal the other 2) - Even a simple 12-hour eating window Sumaya Kazi lost 50 pounds (22 kg) doing 36-hour fasts 3 days a week. She says the first 2 weeks were brutal (hungry as hell), but then: mental clarity, steady energy, no more lethargy after meals, and the weight melted off. Experts on the panel: - It improves insulin sensitivity, lowers blood pressure, triggers cellular repair/autophagy - Metabolism actually speeds up (up to 10% in studies) — the “starvation mode” fear is a myth (takes 72+ hours to slow) - Best results when eating window overlaps morning (when digestion enzymes are optimized) The biggest win? You don’t have to obsess over calories or food rules on eat days — just stay consistent with the window. Have you tried intermittent fasting yet? What window worked (or didn’t) for you — 16:8, 18:6, 5:2, or something else? Your results / questions 👇

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Fasting is Not Healthy But you’ve heard it cures everything right? Well there are many reasons why fasting might not be the best move for you trying to restore your health Telling the old grandma who cannot make it up the stairs to “just fast for the autophagy and repair” is asinine Well how do you repair? With nutrients, from eating. The issue here is that most people are eating trash and if they are eating animal foods they’re cooking or pasteurizing it - negating a lot of the nutrients inside. If your body can’t get what it needs to fulfil the constant repair and healing process, it’ll begin to break itself down. A constant flow diet of raw animal foods is the best thing you can do for healing, especially when done from a place of depletion. As always, there are exceptions like spiritual reasons or to challenge oneself - but in general in our society of poor health I think the focus should be on eating more better foods, not eating nothing.
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Fasting is Not Healthy But you’ve heard it cures everything right? Well there are many reasons why fasting might not be the best move for you trying to restore your health Telling the old grandma who cannot make it up the stairs to “just fast for the autophagy and repair” is asinine Well how do you repair? With nutrients, from eating. The issue here is that most people are eating trash and if they are eating animal foods they’re cooking or pasteurizing it - negating a lot of the nutrients inside. If your body can’t get what it needs to fulfil the constant repair and healing process, it’ll begin to break itself down. A constant flow diet of raw animal foods is the best thing you can do for healing, especially when done from a place of depletion. As always, there are exceptions like spiritual reasons or to challenge oneself - but in general in our society of poor health I think the focus should be on eating more better foods, not eating nothing.

⚡️🌞 Sol Brah 🌞🐬

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David Sinclair’s #1 anti-aging hack: Skip a meal or two every day. He’s on one-meal-a-day and says he got his 20-year-old body back, feels sharper, sleeps better, and has steady energy. Fasting flips on the same longevity genes (like sirtuins) our ancestors used to survive hard times. His tip: Don’t go cold turkey. Give it at least two weeks, your body adapts and the hunger fades. Multiple studies (including human trials) show time-restricted eating and intermittent fasting improve metabolic health, insulin sensitivity, reduce inflammation, and activate cellular repair (autophagy). Animal studies link it to longer lifespan, while human data supports better markers of biological age. What’s your take, could skipping one meal a day be one of the highest-leverage things you can do for longevity?
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David Sinclair’s #1 anti-aging hack: Skip a meal or two every day. He’s on one-meal-a-day and says he got his 20-year-old body back, feels sharper, sleeps better, and has steady energy. Fasting flips on the same longevity genes (like sirtuins) our ancestors used to survive hard times. His tip: Don’t go cold turkey. Give it at least two weeks, your body adapts and the hunger fades. Multiple studies (including human trials) show time-restricted eating and intermittent fasting improve metabolic health, insulin sensitivity, reduce inflammation, and activate cellular repair (autophagy). Animal studies link it to longer lifespan, while human data supports better markers of biological age. What’s your take, could skipping one meal a day be one of the highest-leverage things you can do for longevity?

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Christopher Hemsworth went from “no way I can fast” to full ketosis superpower on day 4. In this clip, he shares how he committed to a 4-day water fast for a project (after initial talks of just intermittent fasting or a day or two turned into “nah, we’re doing four”). Expectation: Maybe ketosis by day 2–3, mental sharpness, alertness. Reality: Days 1–3 felt flat. Then on day 4, during spearfishing, “it kicked in and things started to percolate.” Science nugget: By day 3–4 of water fasting, most people enter deep ketosis—liver glycogen depletes, fat breakdown ramps up, ketones become the brain’s primary fuel (up to 70% of energy), often leading to improved focus, reduced inflammation, and that classic “fasting clarity” many describe as a mental edge. Clip from this 45-second gem—Hemsworth proving the real magic usually hits when you think you’ve hit the wall. Ever pushed through a multi-day fast and felt that switch flip? Or does day 4 still sound like pure torture? Your fasting stories — drop them below 👇
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Christopher Hemsworth went from “no way I can fast” to full ketosis superpower on day 4. In this clip, he shares how he committed to a 4-day water fast for a project (after initial talks of just intermittent fasting or a day or two turned into “nah, we’re doing four”). Expectation: Maybe ketosis by day 2–3, mental sharpness, alertness. Reality: Days 1–3 felt flat. Then on day 4, during spearfishing, “it kicked in and things started to percolate.” Science nugget: By day 3–4 of water fasting, most people enter deep ketosis—liver glycogen depletes, fat breakdown ramps up, ketones become the brain’s primary fuel (up to 70% of energy), often leading to improved focus, reduced inflammation, and that classic “fasting clarity” many describe as a mental edge. Clip from this 45-second gem—Hemsworth proving the real magic usually hits when you think you’ve hit the wall. Ever pushed through a multi-day fast and felt that switch flip? Or does day 4 still sound like pure torture? Your fasting stories — drop them below 👇

Camus

306,641 views • 5 months ago

A Harvard professor who's studied aging for 30 years says one of the most powerful longevity tools on Earth is free. Fasting. David Sinclair explained what happens at the cellular level when you stop eating food for long periods of time: Your body has proteins called sirtuins. They're the conductors of your cellular orchestra - telling each gene when to turn on and off, keeping every cell's identity intact. But sirtuins need fuel called NAD to function. By age 50, your NAD levels drop by HALF. Your conductors are running on empty. Your cells start losing their identity. Fasting raises NAD back up. It reactivates the sirtuins and preserves the epigenome. Sinclair mentions it's only useful if you're already meeting nutrient and micronutrient intake as well. He himself skips breakfast daily and tries to go until late afternoon before eating. Once a month, he fasts for 3 full days because deep cellular recycling - called chaperone-mediated autophagy - only kicks in after about 2 and a half to 3 days. He called three meals a day "craziness" and said the idea that breakfast is the most important meal of the day was "marketing from the early 20th century" by cereal companies. Fasting is just one of the strategies he uses for optimal health. — David Sinclair
1:36

A Harvard professor who's studied aging for 30 years says one of the most powerful longevity tools on Earth is free. Fasting. David Sinclair explained what happens at the cellular level when you stop eating food for long periods of time: Your body has proteins called sirtuins. They're the conductors of your cellular orchestra - telling each gene when to turn on and off, keeping every cell's identity intact. But sirtuins need fuel called NAD to function. By age 50, your NAD levels drop by HALF. Your conductors are running on empty. Your cells start losing their identity. Fasting raises NAD back up. It reactivates the sirtuins and preserves the epigenome. Sinclair mentions it's only useful if you're already meeting nutrient and micronutrient intake as well. He himself skips breakfast daily and tries to go until late afternoon before eating. Once a month, he fasts for 3 full days because deep cellular recycling - called chaperone-mediated autophagy - only kicks in after about 2 and a half to 3 days. He called three meals a day "craziness" and said the idea that breakfast is the most important meal of the day was "marketing from the early 20th century" by cereal companies. Fasting is just one of the strategies he uses for optimal health. — David Sinclair

John Cumbers

231,777 views • 5 months ago

Fasting's the most underrated longevity hack on Earth. Doctors said skipping meals destroys your metabolism... Yet fasting is proven to boost your hormones, burn toxic fat, and repair DNA damage naturally. Here are 7 insane fasting benefits (bookmark this):👇️️️️️️ 1. Activates Autophagy Autophagy kicks in after 12–16 hours of fasting. It's your built-in cleanup system, recycling toxic and old cells into new, fresh ones. It also removes toxic debris linked to Alzheimer's, cancer, & accelerated aging. 2. Burns excess fat Fasting flips your body's fuel switch. When glycogen runs low, it start breaking down stored fat into ketones for energy. And the fact that no more calories are coming in your body... Means you're now forced to burn your own fat. 3. Boosts your hormones Fasting increases human growth hormone (HGH) by up to 5x baseline levels. Higher HGH means: - Faster fat loss - Enhanced recovery - Preserved lean muscle It also improves testosterone in men by reducing insulin resistance. 4. Repairs DNA damage With no food to process, your cells focus on SURVIVAL: - Repairing DNA strands - Cleaning out broken parts - Recycling damaged proteins Fasting's one of the few medicines that helps you rebuild from the inside out naturally. 5. Enhances Insulin Sensitivity Fasting gives your pancreas a break from constant insulin production. Over time, your cells become more responsive to insulin → better glucose control & lower diabetes risk. One study found 16:8 fasting improved insulin sensitivity by ~30% in just 8 weeks. I've found a supplement that increases fasting's benefits by 5X. It keeps insulin low, stabilizes energy, even lets you stay lean year-round. It allows me to stay at 10–12% body fat all year effortlessly, without energy crashes. Here's the one I use (AMAZON PRODUCT LINK): 6. Lowers Inflammation Fasting suppresses inflammatory cytokines like IL-6 and TNF-alpha — the molecular triggers behind: - Brain fog - Chronic pain - Slow recovery By quieting that response, your body heals faster and ages slower. I use fasting daily for the past year and here's exactly why: It gives me: - More energy - Leaner body - Better focus And I feel more alive than EVER. I've made a guide with my fasting protocol. Comment "Fasting" and I'll send it over. (Must Follow so I can DM) 🤝 *Every body works differently, this is not medical advice, just what worked on me." *Always consult a health expert before following any protocols." *Affiliate links included.*
0:30

Fasting's the most underrated longevity hack on Earth. Doctors said skipping meals destroys your metabolism... Yet fasting is proven to boost your hormones, burn toxic fat, and repair DNA damage naturally. Here are 7 insane fasting benefits (bookmark this):👇️️️️️️ 1. Activates Autophagy Autophagy kicks in after 12–16 hours of fasting. It's your built-in cleanup system, recycling toxic and old cells into new, fresh ones. It also removes toxic debris linked to Alzheimer's, cancer, & accelerated aging. 2. Burns excess fat Fasting flips your body's fuel switch. When glycogen runs low, it start breaking down stored fat into ketones for energy. And the fact that no more calories are coming in your body... Means you're now forced to burn your own fat. 3. Boosts your hormones Fasting increases human growth hormone (HGH) by up to 5x baseline levels. Higher HGH means: - Faster fat loss - Enhanced recovery - Preserved lean muscle It also improves testosterone in men by reducing insulin resistance. 4. Repairs DNA damage With no food to process, your cells focus on SURVIVAL: - Repairing DNA strands - Cleaning out broken parts - Recycling damaged proteins Fasting's one of the few medicines that helps you rebuild from the inside out naturally. 5. Enhances Insulin Sensitivity Fasting gives your pancreas a break from constant insulin production. Over time, your cells become more responsive to insulin → better glucose control & lower diabetes risk. One study found 16:8 fasting improved insulin sensitivity by ~30% in just 8 weeks. I've found a supplement that increases fasting's benefits by 5X. It keeps insulin low, stabilizes energy, even lets you stay lean year-round. It allows me to stay at 10–12% body fat all year effortlessly, without energy crashes. Here's the one I use (AMAZON PRODUCT LINK): 6. Lowers Inflammation Fasting suppresses inflammatory cytokines like IL-6 and TNF-alpha — the molecular triggers behind: - Brain fog - Chronic pain - Slow recovery By quieting that response, your body heals faster and ages slower. I use fasting daily for the past year and here's exactly why: It gives me: - More energy - Leaner body - Better focus And I feel more alive than EVER. I've made a guide with my fasting protocol. Comment "Fasting" and I'll send it over. (Must Follow so I can DM) 🤝 *Every body works differently, this is not medical advice, just what worked on me." *Always consult a health expert before following any protocols." *Affiliate links included.*

Achilleas

66,492 views • 10 months ago

Important tips to reduce Diabetes Risk: SLEEP-RELATED FACTORS: 1. Sleep for 7-9 hours at nights 2. Avoid sleeping lesser than 5 hours 3. Avoid oversleeping (more than 10 hours) 4. Avoid daytime napping of more than one hour 5. Avoid exposure to bright lights during night time (sleep) 6. Morning chronotype (sleeping early and getting up early) is healthier. DIET-RELATED FACTORS: 1. Restrict carbohydrate consumption 2. Avoid sugary drinks such as soft drinks and packaged fruit juices 3. Do not skip breakfast (if you are not practicing intermittent fasting), 4. Intermittent fasting with eating window of less than 10 hours (under medical supervision) 5. Avoid snacking in between meals 6. Prefer whole fruits over fresh fruit juices, 7. Minimize consumption of fruits with higher glycemic index 8. Reduce consumption of starchy vegetables such as potatoes PHYSICAL ACTIVITY RELATED FACTORS: 1. Regular aerobic exercises, 2. Strength training, 3. Short walk after meals 4. Short walking break every 45 minutes during periods of prolonged sitting 5. Reduce total sitting (sedentary time) #diabetes #DiabetesAwarenesss
8:51

Important tips to reduce Diabetes Risk: SLEEP-RELATED FACTORS: 1. Sleep for 7-9 hours at nights 2. Avoid sleeping lesser than 5 hours 3. Avoid oversleeping (more than 10 hours) 4. Avoid daytime napping of more than one hour 5. Avoid exposure to bright lights during night time (sleep) 6. Morning chronotype (sleeping early and getting up early) is healthier. DIET-RELATED FACTORS: 1. Restrict carbohydrate consumption 2. Avoid sugary drinks such as soft drinks and packaged fruit juices 3. Do not skip breakfast (if you are not practicing intermittent fasting), 4. Intermittent fasting with eating window of less than 10 hours (under medical supervision) 5. Avoid snacking in between meals 6. Prefer whole fruits over fresh fruit juices, 7. Minimize consumption of fruits with higher glycemic index 8. Reduce consumption of starchy vegetables such as potatoes PHYSICAL ACTIVITY RELATED FACTORS: 1. Regular aerobic exercises, 2. Strength training, 3. Short walk after meals 4. Short walking break every 45 minutes during periods of prolonged sitting 5. Reduce total sitting (sedentary time) #diabetes #DiabetesAwarenesss

Dr Sudhir Kumar MD DM

65,988 views • 1 year ago