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Anthropologist Michael P. Masters made two false claims on Joe Rogan’s latest episode. First, he incorrectly claimed that “we all start out as females.” This is a widespread misconception. In reality, humans begin development in a sexually undifferentiated state with bipotential gonads. Sexual differentiation occurs around weeks 6–8 of...

404,468 просмотров • 6 месяцев назад •via X (Twitter)

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A biological anthropologist Dr. Michael P. Masters just claimed on Joe Rogan that human sex change is possible because of a disorder where "females turn into males at puberty." He makes 7 false claims. Let's break it down. 1. He first claims, "We all start out as females." No, we all start genetically sexed and physically undifferentiated, with bipotential gonads, the primordial genital ducts for both sexes, and a cloaca (Wolpert et al, 2019). Note these are not female gonads or genitalia. Around the 6th week, genetics differentiate our neutral gonads into testes OR ovaries, and then genetics and hormonal signaling from the gonad eliminates one duct and builds the other one. Thus, sex development begins physically neutral and diverges down EITHER the male OR female path due to genetics (Rey et al. 2020). 2. He claims "A population on a pacific island grow up as female until puberty transforms some of them into males." Certain isolated island communities have high rates of what's called 5-alpha reductase deficiency (5-ARD), a MALE ONLY disorder of sex development that causes a male fetus (with testes) to not produce enough DHT, the hormone required for the development of the male's penis, scrotum, and testicular descent (Kumar et al, 2022). At puberty, the surge of testosterone FROM THEIR TESTES causes masculinization of their external genitalia and body, with some descent of the testes and development of the penis and scrotum. These males were NEVER females. They are born as males WITH TESTES with underdeveloped external genitals. 3. He claims, "The population is insensitive to DHT." No, those with the disorder have an enzyme deficiency, where they cannot PRODUCE enough of the enzyme to convert testosterone into DHT. Their bodies can respond to DHT normally. It's that they cannot produce enough of it to guide the external genital development of the male fetus (Kang et al. 2014). 4. He claims, "Their ovaries descend and become testes at puberty." No, they never had ovaries. Like all other males, males with 5-ARD have the SRY gene. This triggers their bipotential gonads to differentiate into testes (Kashimada & Koopman, 2010). This does not happen during puberty. This happens at 6 weeks gestation. Just because their testes may not descend does not make them ovaries. 5. He claims, it's called "pseudohermaphroditism." No, it's called 5-alpha reductase deficiency. Medicine has abandoned the use of the term pseudohermaphroditism since early 2000s because it obscures the actual reality of these rare conditions, and is "scientifically specious and clinically problematic" (Dreger et al. 2005). 6. He claims, "They turn into the opposite sex." No, they start out in utero as males and remain as males for life. Just because they were not able to fully develop their external genitals does not make them females. They are males with testes who could not fully develop the penis and scrotum due to lack of DHT. Humans cannot change sex. We are gonochoric--a species whose individuals are male or female for life, determined by their genetics (Holub & Shackelford.) 7. He claims, "It doesn't do anything. Natural selection wouldn't select against it. It's just weird." No, the disorder causes many issues with male fertility. First, low DHT can impair the growth and differentiation of sperm cells and the growth of the prostate, causing them to have a prostate that is 1/10th the healthy size. Small prostates mean that semen volumes are low, harming sperm transport and motility. Second, undescended testes can also disrupt the careful balance of temperature for sperm creation (Kang, Imperato-McGinley, Zhu, & Rosenwaks, 2014). Parroting false claims about these rare disorders like 5-ARD hurts the public's understanding of these conditions, makes people believe falsehoods about human biology, and can harm the evidence-based treatment of the individuals who have these disorders. Scientific sources for further reading: Wolpert, L., Tickle, C., & Martinez Arias, A. (2019). Principles of Development (6th ed.). Oxford University Press. Rey, R., Josso, N., Racine, C. (2020). Sexual differentiation. In: Endotext. South Dartmouth, MDText, Inc. Kumar, G., & Barboza-Meca, J. J. (2022). 5-Alpha-Reductase Deficiency. In StatPearls. StatPearls Publishing. Kang, H., Imperato-McGinley, J., Zhu, Y.-S., & Rosenwaks, Z. (2014). The effect of 5a-reductase-2 deficiency on human fertility. Fertility and Sterility, 101(2), 320–326. Kashimada, K., Koopman, P. (2010). Sry, the master switch in mammalian sex determination. Development, 137. Dreger, A. D., Chase, C., Sousa, A., Gruppuso, P. A., & Frader, J. (2005). Changing the nomenclature/taxonomy for intersex: A scientific and clinical rationale. Journal of Pediatric Endocrinology and Metabolism, 18(8), 729–733. Holub, A., Shackelford, T. (2021). Gonochorism. Encyclopedia of Animal Cognition and Behavior. Springer.

Zachary Elliott

229,327 просмотров • 6 месяцев назад

Recently, on Chris Williamson's podcast, said it's "not true" that "there are only two sexes" in humans. He also claimed that "there are people with male brains in female bodies, and conversely." I'd like to address both claims directly to help clear up some confusion. THE SEX BINARY First, Eric used the terms “sex” and “gender” interchangeably, and when prompted to clarify he explicitly claimed sex (as well as gender) was not binary. He brought up people with intersex conditions as the reason why he believes this. But the existence of people with rare intersex conditions does not in any way negate the reality of the sex binary. That’s because the sex binary simply means “there are only two sexes,” and this is true because there are only two types of gametes. Males and females are universally defined by the gametes they have the function to produce, with males producing small gametes (sperm) and females producing large ones (ova). The sex binary does not mean “everyone is either male or female.” This may seem overly pedantic, bit it’s an important distinction. It may be possible that a person can be so sexually ambiguous as to defy categorization as either male or female, but sex ambiguity is not a third sex. The existence and prevalence of complex DSDs or so-called “intersex” conditions is irrelevant to the question of how many sexes there are. So, on this point, Eric is simply confused about what sexes are at a fundamental level. There are only two sexes because there are only two types of gametes—sperm and ova. I agree with Eric that we need to be compassionate and accommodating of people who might be sexually ambiguous. But claiming it’s “no true” that “there are only two sexes’ is definitely not the way to go about this. Apart from being incorrect, it carries a tremendous amount of baggage that I believe Eric and I would both agree must be avoided. BRAIN SEX Lastly, Eric said he believed it’s true that "there are people with male brains in female bodies, and conversely." Again, I believe this is rooted in a fundamental misunderstanding about what sexes are. Simply put, brains do not and cannot have their own sex that differs from the body. Whole organisms have a sex, individual organs do not. However, it is true that various body parts and organs can differ in the degree of how masculinized or feminized they are or appear. Hands are a great example of this, as their morphology is sensitive to in utero testosterone levels. As a result, some females have very masculine looking hands, and some males have very feminine looking hands. But no matter how masculine a female’s hands may be, it would never be correct to say that she has “male hands on a female body.” The same goes for brains and any other organ or appendage. While the brains of males and females can vary in the degree to which they are masculinized or feminized, it is never the case that a person can possess the brain of the opposite sex, even if they deeply feel that way. Eric, I’m a fan of yours and believe you possess tremendous insight on many topics, but I think you need to give this specific topic some more thought. I would be more than happy to chat with you about this if you’re ever interested. I think it's extremely important. Watch the whole podcast at the link below. 🔗

Colin Wright

1,059,715 просмотров • 2 лет назад

STOP USING PEOPLE WITH DSD AS PROPS FOR GENDER IDEOLOGY This is Nick, better known as That XXY Guy. Nick has a Difference of Sex Development, a medical condition. He is also a man. A male. And he is furious that activists keep dragging people like him into arguments about transgender identity as though their medical conditions prove that human sex is imaginary, fluid, or somehow no longer male and female. His message is blunt because it needs to be: people with DSD are not a mythical “third sex”. They are not political exhibits. They are not a convenient shield to be held up every time someone points out that sex is real. Nick is male. His XXY condition does not make him less male. It does not make him “both sexes”. And it certainly does not exist to prop up an ideology he does not consent to represent. More importantly, this is not Nick standing alone. The UK charity dsdfamilies, which supports children, young people and families living with Differences of Sex Development, has repeatedly warned against conflating DSD with transgender identity. DSD concerns complex physical differences in sex development. Transgender identity is a separate issue entirely. After the Supreme Court ruling, dsdfamilies warned against the “oversimplification, misrepresentation and weaponisation of DSD/Intersex by third parties”, stating that such misuse increases stigma and may discourage people from accessing support. Read that again. The people activists keep using as their biological trump card are telling them to stop. This is what ideological capture looks like: people with real medical conditions are spoken over, misrepresented and reduced to poster children for a political argument they never asked to carry. So listen to Nick. Stop claiming people with DSD abolish the reality of male and female. Stop pretending their conditions are interchangeable with transgender identity. Stop using other people’s bodies, medical needs and lived experience as ammunition for an ideology that does not even respect what they are saying. People with DSD need proper medical support, dignity, understanding and a voice of their own. They do not need activists appropriating their conditions to deny biological reality. #sexisbinary

The Heartlands Tribune

21,959 просмотров • 1 месяц назад

My name is Chris Elston, and I’m here to speak for children being irreversibly harmed by health professionals practicing what is falsely referred to as gender-affirming care. It is not caring to stop the development of children with puberty blockers. These are repurposed chemical castration and cancer drugs. It is not caring to alter their development with opposite-sex hormones. Every systematic review of the scientific literature shows that children are being harmed, and that scientific rigour is non-existent. Activist organizations pushing ideology have hijacked the medical community, and what is being done is nothing more than a live, unregulated experiment on kids. It is one of the great deceptions of our time to teach children that they might have been born in the wrong bodies! Affirming care would be to tell them that they are beautiful just as they are. No drugs or scalpels needed! Instead, children are being sterilized, and are having healthy body parts cut off. Overwhelmingly, these kids are autistic, have other mental health comorbidities, and many have suffered trauma or abuse. Girls as young as 12 are having their breasts removed, and 16-year-old boys are being castrated. State encroachment on parental rights is worsening outcomes. Here in Geneva, a child was taken from her parents because they refuse to transition her. Children have the human right to grow up with their bodies intact. It is time the Member States of the United Nations use the resolutions, procedures, and other tools at their disposal to stop this child abuse!

Billboard Chris 🌎

45,930 просмотров • 4 месяцев назад

On this Transgender Day of Remembrance, we remember my speech at the United Nations Human Rights Council. My name is Chris Elston, and I am to here to speak for children being irreversibly harmed by health professionals practicing what is falsely referred to as gender-affirming care. It is not caring to stop the development of children with puberty blockers. These are repurposed chemical castration and cancer drugs. It is not caring to alter their development with opposite-sex hormones. Every systematic review of the scientific literature shows that children are being harmed, and that scientific rigour is non-existent. Activist organizations pushing ideology have hijacked the medical community, and what is being done is nothing more than a live, unregulated experiment on kids. It is one of the great deceptions of our time to teach children that they might have been born in the wrong bodies! Affirming care would be to tell them that they are beautiful just as they are. No drugs or scalpels needed! Instead, children are being sterilized, and are having healthy body parts cut off. Overwhelmingly, these kids are autistic, have other mental health comorbidities, and many have suffered trauma or abuse. Girls as young as 12 are having their breasts removed, and 16-year-old boys are being castrated. State encroachment on parental rights is worsening outcomes. Here in Geneva, a child was taken from her parents because they refuse to transition her. Children have the human right to grow up with their bodies intact. It is time the Member States of the United Nations use the resolutions, procedures, and other tools at their disposal to stop this child abuse!

Billboard Chris 🌎

46,511 просмотров • 7 месяцев назад

“Baby killers” are shouting at us, wherever we are. Have an honest look at these babies…and at these palestinian killers. In which other society the children are forced to protect a terrorist who KNOWS that IDF won’t drop a bomb on him while he is surrounded by kids ?! Would u put your own children in the harms way to protect yourself, as a Man, as a Dad ?! Would u have a moral shock seeing this and thinking how many time you fall for this tragic palestinian propaganda ? Would you call this abomination and total disregard for the children’s lives… “rezistance” ?! Every day, since Oct7th, the children of Gaza were forced to shield terrorists. And every time when these truly innocent kids died, like they do anywhere else in a just war, specially when NOBODY is protecting them, every time they used their death to incriminate Israel. And when they haven’t got any new videos with their own children dead, they fake it. They used dolls, they forced their kids to play dead, they used video or pictures of kids dead from other Wars, years ago. They knew that this is their biggest weapon of “resistance” - convincing a large portion of the gullible West (media first) that they are the victims of the “baby killers”. Inversion of REALITY and islamic propaganda at its highest level of insanity. All to make Israel look bad and the terrorists to be seen as …victims. We are not the same. And we will never be. As parents, as Mothers and Fathers, as societies, we are no match with Islam. Let Israel save these kids from their own parents, from their terrorists abusers. This is how we care about the children in Gaza. Not by supporting the terrorists who wants them dead for PR reasons… 🎥 via An Israeli mother .
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“Baby killers” are shouting at us, wherever we are. Have an honest look at these babies…and at these palestinian killers. In which other society the children are forced to protect a terrorist who KNOWS that IDF won’t drop a bomb on him while he is surrounded by kids ?! Would u put your own children in the harms way to protect yourself, as a Man, as a Dad ?! Would u have a moral shock seeing this and thinking how many time you fall for this tragic palestinian propaganda ? Would you call this abomination and total disregard for the children’s lives… “rezistance” ?! Every day, since Oct7th, the children of Gaza were forced to shield terrorists. And every time when these truly innocent kids died, like they do anywhere else in a just war, specially when NOBODY is protecting them, every time they used their death to incriminate Israel. And when they haven’t got any new videos with their own children dead, they fake it. They used dolls, they forced their kids to play dead, they used video or pictures of kids dead from other Wars, years ago. They knew that this is their biggest weapon of “resistance” - convincing a large portion of the gullible West (media first) that they are the victims of the “baby killers”. Inversion of REALITY and islamic propaganda at its highest level of insanity. All to make Israel look bad and the terrorists to be seen as …victims. We are not the same. And we will never be. As parents, as Mothers and Fathers, as societies, we are no match with Islam. Let Israel save these kids from their own parents, from their terrorists abusers. This is how we care about the children in Gaza. Not by supporting the terrorists who wants them dead for PR reasons… 🎥 via An Israeli mother .

miha schwartzenberg

10,351 просмотров • 1 год назад