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Evo: a foundation model for genomics! Using a well suited architecture, Evo learns from billions of bp of genomic sequence and performs well on several zero-shot prediction tasks on RNA, DNA and protein. Beautiful paper from Brian Hie & Patrick Hsu at Arc Institute

52,365 просмотров • 2 лет назад •via X (Twitter)

Комментарии: 14

Фото профиля Julia Bauman
Julia Bauman2 лет назад

Preprint link here:

Фото профиля ksminnovation
ksminnovation1 год назад

Dr. Tal Patalon explores how AI mega initiatives like the $500B Stargate project & AI-powered genomic analysis by Illumina & NVIDIA are transforming healthcare. @TalPatalon @forbes @edengallery_ #AIinHealthcare #PrecisionMedicine #Multiomics #HealthTech

Фото профиля Matt Durrant
Matt Durrant2 лет назад

@BrianHie @pdhsu @arcinstitute Thank you for highlighting our work!

Фото профиля Dmitry Penzar
Dmitry Penzar2 лет назад

@BrianHie @pdhsu @arcinstitute What are you about the fact their model do activity prediction worse than gc-content?

Фото профиля Misha
Misha2 лет назад

@BrianHie @pdhsu @arcinstitute very good presentation

Фото профиля Ashton C Trotman-Grant
Ashton C Trotman-Grant2 лет назад

@BrianHie @pdhsu @arcinstitute Yes! Awesome summary Julia. This paper is so cool

Фото профиля Nishant Jha
Nishant Jha2 лет назад

@BrianHie @pdhsu @arcinstitute Been noodling on a playground for evo here:

Фото профиля ريان
ريان2 лет назад

@BrianHie @pdhsu @arcinstitute Julia — what do you think about the fact that they claim to generate functional CRISPR-Cas systems without experimental validation?

Фото профиля Julia Bauman
Julia Bauman2 лет назад

@BrianHie @pdhsu @arcinstitute I think that they’re going to do the experimental validation :)

Фото профиля Dr Rob Leigh
Dr Rob Leigh2 лет назад

@BrianHie @pdhsu @arcinstitute Paging Dr @Cian_Smyth

Фото профиля Neuropunk
Neuropunk2 лет назад

@BrianHie @pdhsu @arcinstitute Its about time we move to fully synthetic biology. This is where all the cures, improvements and the most deadly weapons of humanity lie

Фото профиля Ryan Metz
Ryan Metz2 лет назад

@BrianHie @pdhsu @arcinstitute Great work

Фото профиля Sean Jackewicz, MD 🧬🛠️
Sean Jackewicz, MD 🧬🛠️2 лет назад

@BrianHie @pdhsu @arcinstitute Oooooo this could be so cool

Фото профиля Bin Shao
Bin Shao2 лет назад

Very nice video! I do hope some day people can create a similar one for our language model…

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114,621 просмотров • 1 год назад

🚨David Friedberg: AI is starting to identify and solve problems on its own “I'll give you a science corner example: there's this Evo 2 model that they publish at the Arc Institute, which Patrick Collison, you know, is the main funder and chairman.” “So that Evo 2 model, they just ingested all the DNA data they could find in the world.” “Trillions and trillions of base paired data that they ingested and then they looked at patterns in DNA. And that's it.” “They had no context for what the DNA represented, they had no context for the concept of genes, none of the structured understanding of what that DNA does, what it is, and you know what it did?” “They fed in the BRCA gene variant and the thing output a warning saying, ‘I think that this is a pathogenic variant to DNA,’ without having any context.” “This is the breast cancer allele.” “And it didn't have any knowledge and it wasn't trained on that at all.” “It had no knowledge that there are pathogenic variants for cancer, and it identified that this was a genetic variant that can cause some sort of pathogenic outcome in the organism.” “That's a great example where there's a lack of understanding at the human level on what really drives some of the patterns in nature, the patterns in society, the patterns in behavior that are kind of emergent phenomena perhaps, that these AI models are starting to identify.”

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