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Here’s a podcast about mitochondrial dysfunction. From all my years of using ketogenic diets like the lion diet for health, getting impacted by mold, experiencing SSRI induced withdrawal/damage, it finally appears like the root cause is mitochondrial dysfunction at a cellular level. The research into this is cutting edge...

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Mikhaila Peterson

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234,699 просмотров • 4 месяцев назад •via X (Twitter)

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My entire SSRI series in one video. What doctors never tell you about SSRI withdrawal. Chris Masterjohn, PhD, Founder and Scientific Director of explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment. 29 million Americans and about 5-10% of the world's population are on SSRIs, which have become the first-line treatment of depression. These can cause sexual dysfunction and emotional blunting in up to half of people, an unclear incidence of sleep disruption, and a rare risk of suicidality, self-harm, and new-onset psychosis. On the other hand, 20-50% of people who go off experience SSRI discontinuation syndrome. This can involve irritability, anxiety, mood problems, crying, dread, suicidal ideation, insomnia, nightmares, excessive dreaming, lethargy, fatigue, headache, tremor, sweating, anorexia, flu-like symptoms, nausea, vomiting, diarrhea, pain, numbness, tingling, feeling like something is crawling on the skin, electric shocks running through the brain or body, rushing noises, visual traces (seeing something persist when it is no longer there, or seeing moving objects leaving illusory streaks of light behind them, etc), dizziness, light-headedness, "brain zaps," vertigo, confusion, difficulty concentrating, amnesia, genital hypersensitivity, and premature ejaculation. A closely related problem is post-SSRI sexual dysfunction (PSSD), which can cause total inability to feel the penis for males or for females the genitals and nipples, loss of sexual pleasure, weak orgasms, decreased libido, erectile dysfunction, and premature ejaculation. PSSD is often associated with general anhedonia, apathy, and poor mood. In this video, I maintain that the reason there are no good solutions to these problems is because we have completely misunderstood the role of serotonin and SSRIs. Serotonin's role is to help mitochondria adapt to changing demands for oxygen-based energy production. SSRIs enhance some of the mechanisms, and interfere with others. They enter the cell and stimulate independent mechanisms of mitochondrial stress adaptation, but in doing so they turn a cyclical and rhythmic pathway into a constantly stimulated one, creating mitochondrial dependence and making mitochondria vulnerable to new-onset dysfunction upon withdrawal. Once they make it to the mitochondria itself, the SSRIs act as mitochondrial toxins. Scientific references for everything can be found in the series on my web site. 0:30 SSRI Side Effects 1:00 SSRI Discontinuation Syndrome and PSSD 11:33 The Problem With Primary Care Doctors and Psychiatrists 14:56 The Reason We Don’t Have Good Solutions Is Because We Don’t Understand the Problem 16:22 Prozac Is a Performance-Enhancing Drug 18:40 Depression and Altitude 19:36 The Truth About Serotonin 25:10 How Serotonin Helps Us Breathe 30:05 Hypoxia Explains Why Serotonin Is So Abundant In the Gut 33:55 Serotonin, Melatonin, and the Mitochondria 35:50 Serotonin and Light 39:25 Intermittent Hypobaric Hypoxia Training 42:56 SSRIs Are Whole-Body, Primarily Non-Brain, Non-Neuronal, Mitochondrial Drugs 44:00 SSRIs and Birth Defects 46:37 SSRIs Deplete Serotonin 48:50 SSRIs Distort the Sigma-1 Receptor From a Cyclical to a Constant Activation 51:10 Different SSRIs Promote Different Ratios of Mitophagy and Mitochondrial Biogenesis 54:00 Going Off SSRIs Causes New-Onset Mitochondrial Dysfunction 58:30 Slow and Parabolic Tapers 1:02:10 What to Do About SSRI Withdrawal Mitochondrial Dysfunction Do You Have Hidden Mitochondrial Dysfunction? Mitochondrial dysfunction is one of the earliest signs of aging and chronic disease—and most people don’t know they have it. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find it here at Mitome™
1:29:03

My entire SSRI series in one video. What doctors never tell you about SSRI withdrawal. Chris Masterjohn, PhD, Founder and Scientific Director of explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment. 29 million Americans and about 5-10% of the world's population are on SSRIs, which have become the first-line treatment of depression. These can cause sexual dysfunction and emotional blunting in up to half of people, an unclear incidence of sleep disruption, and a rare risk of suicidality, self-harm, and new-onset psychosis. On the other hand, 20-50% of people who go off experience SSRI discontinuation syndrome. This can involve irritability, anxiety, mood problems, crying, dread, suicidal ideation, insomnia, nightmares, excessive dreaming, lethargy, fatigue, headache, tremor, sweating, anorexia, flu-like symptoms, nausea, vomiting, diarrhea, pain, numbness, tingling, feeling like something is crawling on the skin, electric shocks running through the brain or body, rushing noises, visual traces (seeing something persist when it is no longer there, or seeing moving objects leaving illusory streaks of light behind them, etc), dizziness, light-headedness, "brain zaps," vertigo, confusion, difficulty concentrating, amnesia, genital hypersensitivity, and premature ejaculation. A closely related problem is post-SSRI sexual dysfunction (PSSD), which can cause total inability to feel the penis for males or for females the genitals and nipples, loss of sexual pleasure, weak orgasms, decreased libido, erectile dysfunction, and premature ejaculation. PSSD is often associated with general anhedonia, apathy, and poor mood. In this video, I maintain that the reason there are no good solutions to these problems is because we have completely misunderstood the role of serotonin and SSRIs. Serotonin's role is to help mitochondria adapt to changing demands for oxygen-based energy production. SSRIs enhance some of the mechanisms, and interfere with others. They enter the cell and stimulate independent mechanisms of mitochondrial stress adaptation, but in doing so they turn a cyclical and rhythmic pathway into a constantly stimulated one, creating mitochondrial dependence and making mitochondria vulnerable to new-onset dysfunction upon withdrawal. Once they make it to the mitochondria itself, the SSRIs act as mitochondrial toxins. Scientific references for everything can be found in the series on my web site. 0:30 SSRI Side Effects 1:00 SSRI Discontinuation Syndrome and PSSD 11:33 The Problem With Primary Care Doctors and Psychiatrists 14:56 The Reason We Don’t Have Good Solutions Is Because We Don’t Understand the Problem 16:22 Prozac Is a Performance-Enhancing Drug 18:40 Depression and Altitude 19:36 The Truth About Serotonin 25:10 How Serotonin Helps Us Breathe 30:05 Hypoxia Explains Why Serotonin Is So Abundant In the Gut 33:55 Serotonin, Melatonin, and the Mitochondria 35:50 Serotonin and Light 39:25 Intermittent Hypobaric Hypoxia Training 42:56 SSRIs Are Whole-Body, Primarily Non-Brain, Non-Neuronal, Mitochondrial Drugs 44:00 SSRIs and Birth Defects 46:37 SSRIs Deplete Serotonin 48:50 SSRIs Distort the Sigma-1 Receptor From a Cyclical to a Constant Activation 51:10 Different SSRIs Promote Different Ratios of Mitophagy and Mitochondrial Biogenesis 54:00 Going Off SSRIs Causes New-Onset Mitochondrial Dysfunction 58:30 Slow and Parabolic Tapers 1:02:10 What to Do About SSRI Withdrawal Mitochondrial Dysfunction Do You Have Hidden Mitochondrial Dysfunction? Mitochondrial dysfunction is one of the earliest signs of aging and chronic disease—and most people don’t know they have it. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find it here at Mitome™

Chris Masterjohn

16,587 просмотров • 9 месяцев назад

I had Tom Benson, CEO of Mitrix on to discuss mitochondrial transplantation. We covered what mitochondria are, the discovery that your body is constantly delivering fresh mitochondria through your bloodstream (people didn’t know that mitochondria were transferred outside the cell until recently!), why we age, what kills mitochondria (stress, smoking, radiation, chemotherapy and certain antibiotics like fluoroquinolones, psych meds), why COVID destroys mitochondria and what that means for long COVID, the Alzheimer's and Parkinson's brain tissue regeneration research their company has already done in mice, what mitochondrial transplantation actually is and how it has already been used in pediatric heart surgery, what a bioreactor growing mitochondria for personal use might look like, and more.
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I had Tom Benson, CEO of Mitrix on to discuss mitochondrial transplantation. We covered what mitochondria are, the discovery that your body is constantly delivering fresh mitochondria through your bloodstream (people didn’t know that mitochondria were transferred outside the cell until recently!), why we age, what kills mitochondria (stress, smoking, radiation, chemotherapy and certain antibiotics like fluoroquinolones, psych meds), why COVID destroys mitochondria and what that means for long COVID, the Alzheimer's and Parkinson's brain tissue regeneration research their company has already done in mice, what mitochondrial transplantation actually is and how it has already been used in pediatric heart surgery, what a bioreactor growing mitochondria for personal use might look like, and more.

Mikhaila Peterson

22,561 просмотров • 3 месяцев назад

🎙️Health Sovereignty: Mitochondria, Light & Nature Ep. 114 with Dr. Alexis Jazmyn My guest today is Dr. Alexis Cowan, PhD,, a Princeton-trained molecular biologist specializing in metabolism, mitochondrial function, and circadian biology. We talk about why modern science has drifted into scientism, how mitochondrial dysfunction sits at the root of nearly every chronic disease, and why reclaiming sovereignty over your health is both radical and necessary. We dive deep into light biology, circadian rhythms, sun exposure, quantum biology, and the incentives that shape (and distort) modern medicine. We also explore Alexis’ personal health journey, her break from academia, her work with Jack Kruse’s ideas, and how Bitcoin, self-custody, and proof-of-work thinking mirror biological truth. → Please like, comment, share & follow — to help me beat the suppressing big tech algorithms & gov. censorship. Thank you!
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🎙️Health Sovereignty: Mitochondria, Light & Nature Ep. 114 with Dr. Alexis Jazmyn My guest today is Dr. Alexis Cowan, PhD,, a Princeton-trained molecular biologist specializing in metabolism, mitochondrial function, and circadian biology. We talk about why modern science has drifted into scientism, how mitochondrial dysfunction sits at the root of nearly every chronic disease, and why reclaiming sovereignty over your health is both radical and necessary. We dive deep into light biology, circadian rhythms, sun exposure, quantum biology, and the incentives that shape (and distort) modern medicine. We also explore Alexis’ personal health journey, her break from academia, her work with Jack Kruse’s ideas, and how Bitcoin, self-custody, and proof-of-work thinking mirror biological truth. → Please like, comment, share & follow — to help me beat the suppressing big tech algorithms & gov. censorship. Thank you!

Efrat Fenigson

16,560 просмотров • 8 месяцев назад

High blood pressure truth (the real cause & solution) Here’s the entire playbook ⬇️ 1970…160/95 1985…140/90 2017…120/80 Now…2026…110/70 And anything higher is dysfunction? That’s catastrophic I’ll prove it 2018 Lancet 1 million adults found NO increased mortality at 150/100 Zero But at 110/70…let’s look 2020 American Journal of Hypertension showed increased in all cause mortality Here’s what really increases blood pressure systemic inflammation insulin resistance and mitochondrial dysfunction let’s rock and roll… And ANYONE can solve it all I’ll show you It’s all in the research packet And it’s FREE! If biology has normal endothelial function, mitochondrial function and insulin sensitivity… meaning they’ve been measured then elevated blood pressure… isn’t pathological it’s compensatory But how many doctors are measuring mitochondrial ATP capacity endothelial function testing vascular reactivity using flow mediated dilation tests or running a continuous glucose monitor? None…they’re treating numbers Your move Never Miss Dr Trevor Bachmeyer The Spartan
2:56

High blood pressure truth (the real cause & solution) Here’s the entire playbook ⬇️ 1970…160/95 1985…140/90 2017…120/80 Now…2026…110/70 And anything higher is dysfunction? That’s catastrophic I’ll prove it 2018 Lancet 1 million adults found NO increased mortality at 150/100 Zero But at 110/70…let’s look 2020 American Journal of Hypertension showed increased in all cause mortality Here’s what really increases blood pressure systemic inflammation insulin resistance and mitochondrial dysfunction let’s rock and roll… And ANYONE can solve it all I’ll show you It’s all in the research packet And it’s FREE! If biology has normal endothelial function, mitochondrial function and insulin sensitivity… meaning they’ve been measured then elevated blood pressure… isn’t pathological it’s compensatory But how many doctors are measuring mitochondrial ATP capacity endothelial function testing vascular reactivity using flow mediated dilation tests or running a continuous glucose monitor? None…they’re treating numbers Your move Never Miss Dr Trevor Bachmeyer The Spartan

Dr Trevor Bachmeyer

27,624 просмотров • 1 месяц назад

Eye-opening interview with Dr. Sarah Myhill exposing the cholesterol myth! "Statins are not rooted in research or science. They are rooted in propaganda." Cholesterol is ESSENTIAL—your body needs it for hormones, vitamin D, cell membranes, brain function, and more. It's not the villain we've been sold. Statins? They block vital pathways (like CoQ10 production), leading to muscle pain, fatigue, accelerated aging, and mitochondrial damage—while the 'benefits' are overhyped and not commensurate with cholesterol reduction alone. The trillion-dollar statin empire thrives on fear, not facts. Time to rethink heart health: focus on real causes like inflammation, poor diet, and mitochondrial dysfunction—not aggressively lowering a natural, life-sustaining substance. Share this vital information with family & friends who are taking harmful statin drugs. Bookmark for future sharing!
1:07

Eye-opening interview with Dr. Sarah Myhill exposing the cholesterol myth! "Statins are not rooted in research or science. They are rooted in propaganda." Cholesterol is ESSENTIAL—your body needs it for hormones, vitamin D, cell membranes, brain function, and more. It's not the villain we've been sold. Statins? They block vital pathways (like CoQ10 production), leading to muscle pain, fatigue, accelerated aging, and mitochondrial damage—while the 'benefits' are overhyped and not commensurate with cholesterol reduction alone. The trillion-dollar statin empire thrives on fear, not facts. Time to rethink heart health: focus on real causes like inflammation, poor diet, and mitochondrial dysfunction—not aggressively lowering a natural, life-sustaining substance. Share this vital information with family & friends who are taking harmful statin drugs. Bookmark for future sharing!

Valerie Anne Smith

57,588 просмотров • 7 месяцев назад

Red light therapy is one of the tools we use at a Paradise For Parents to help improve memory and cognition in our residents. It works by fixing what’s broken at the cellular level. Let me explain. Your mitochondria are like tiny batteries in your cells. When the battery runs well, it produces ATP (energy). Energy powers everything your brain cells do—storing memories, processing thoughts, and communicating with each other. When the battery runs poorly, it leaks “acid” or reactive oxygen species (ROS). ROS triggers inflammation, causing brain cells to stop communicating, malfunction, and die—resulting in dementia over time. Red light (660-900nm wavelengths) acts like a switch that turns on mitochondrial efficiency so it produces more energy and allow your cells to get the energy it needs. When placed around the head, the light goes straight through bone into the brain's cortex, energizing the mitochondria where they're needed most. It helps them: • Produce more ATP • Reduce inflammation • Lower reactive oxygen species • Improve cellular energy We use red light helmets and panels. Residents sit with their faces close to the panels for a few minutes in the morning—that's it. Combined with other health modalities like carnivore/keto diet, regular sunlight and exercise, the results are astounding.
0:36

Red light therapy is one of the tools we use at a Paradise For Parents to help improve memory and cognition in our residents. It works by fixing what’s broken at the cellular level. Let me explain. Your mitochondria are like tiny batteries in your cells. When the battery runs well, it produces ATP (energy). Energy powers everything your brain cells do—storing memories, processing thoughts, and communicating with each other. When the battery runs poorly, it leaks “acid” or reactive oxygen species (ROS). ROS triggers inflammation, causing brain cells to stop communicating, malfunction, and die—resulting in dementia over time. Red light (660-900nm wavelengths) acts like a switch that turns on mitochondrial efficiency so it produces more energy and allow your cells to get the energy it needs. When placed around the head, the light goes straight through bone into the brain's cortex, energizing the mitochondria where they're needed most. It helps them: • Produce more ATP • Reduce inflammation • Lower reactive oxygen species • Improve cellular energy We use red light helmets and panels. Residents sit with their faces close to the panels for a few minutes in the morning—that's it. Combined with other health modalities like carnivore/keto diet, regular sunlight and exercise, the results are astounding.

A Paradise for Parents

46,738 просмотров • 7 месяцев назад

The Hidden Secret to Never Getting Cancer: Protect Your Mitochondria Cancer doesn’t just appear out of nowhere—it starts when a normal cell’s mitochondria break down and become dysfunctional. According to Dr. Eric Berg, the key to cancer prevention lies in safeguarding these cellular powerhouses. Here’s how: 1. Optimize Vitamin D Levels Maintain blood levels of 70–80 ng/mL. Vitamin D is a mitochondrial supercharger, bolstering your immune system and keeping cells functioning optimally. 2. Harness the Power of Fasting Regular intermittent fasting, combined with periodic prolonged fasts (like a 2-day water fast monthly), triggers autophagy—your body’s natural cleanup process—removing damaged cells and rejuvenating mitochondria. 3. Cut Refined Carbs & Starches High-carb diets are mitochondrial kryptonite. Switch to a low-carb approach to reduce oxidative stress and protect cellular energy production. 4. Load Up on Mitochondria-Boosting Foods Garlic, onions, and cruciferous veggies (broccoli, kale, Brussels sprouts) are packed with sulfur compounds that detoxify and fortify mitochondria. 5. Avoid Excess Iron Iron overload—from supplements, fortified foods, or cast-iron cookware—accelerates mitochondrial damage. Monitor your intake to keep iron in check. 6. Exercise Consistently Movement isn’t just for fitness; it’s a mitochondrial elixir. Regular exercise enhances their efficiency, reduces inflammation, and lowers cancer risk. The science is clear: Cancer thrives in a body with weak mitochondria. Strengthen them, and you build an impenetrable defense. Your health is in your hands.
0:57

The Hidden Secret to Never Getting Cancer: Protect Your Mitochondria Cancer doesn’t just appear out of nowhere—it starts when a normal cell’s mitochondria break down and become dysfunctional. According to Dr. Eric Berg, the key to cancer prevention lies in safeguarding these cellular powerhouses. Here’s how: 1. Optimize Vitamin D Levels Maintain blood levels of 70–80 ng/mL. Vitamin D is a mitochondrial supercharger, bolstering your immune system and keeping cells functioning optimally. 2. Harness the Power of Fasting Regular intermittent fasting, combined with periodic prolonged fasts (like a 2-day water fast monthly), triggers autophagy—your body’s natural cleanup process—removing damaged cells and rejuvenating mitochondria. 3. Cut Refined Carbs & Starches High-carb diets are mitochondrial kryptonite. Switch to a low-carb approach to reduce oxidative stress and protect cellular energy production. 4. Load Up on Mitochondria-Boosting Foods Garlic, onions, and cruciferous veggies (broccoli, kale, Brussels sprouts) are packed with sulfur compounds that detoxify and fortify mitochondria. 5. Avoid Excess Iron Iron overload—from supplements, fortified foods, or cast-iron cookware—accelerates mitochondrial damage. Monitor your intake to keep iron in check. 6. Exercise Consistently Movement isn’t just for fitness; it’s a mitochondrial elixir. Regular exercise enhances their efficiency, reduces inflammation, and lowers cancer risk. The science is clear: Cancer thrives in a body with weak mitochondria. Strengthen them, and you build an impenetrable defense. Your health is in your hands.

Camus

213,745 просмотров • 10 месяцев назад

SUPPLEMENTING YOUR WORK ENVIRONMENT WITH AN INCANDESCENT LIGHT BULB IMPROVES MITOCHONDRIAL FUNCTION! - A brand new (Jan 23th, 2026) paper published by Glen Jeffery and Edward Barrett demonstrates how adding a 60 W incandescent lamp to participants work desk dramatically improves color contrast, or a proxy for color vision. The intervention here is simply placing an incandescent lightbulb on the desk without direct irradiation on participants. And this is huge: “we have obtained significant balanced improvements in both the protan and tritan range. Previously, exposure to restricted experimental 670 nm resulted in improvements biased strongly in favour of only tritan function. Hence, exposure to full spectrum lighting results in a balanced pattern of improvement in visual performance.” The mechanism seems to be mitochondrial in nature. Short wavelength light, which is dominated in standard LED lighting, reduces mitochondrial function. There’s a reduction in mitochondria ATP production, and therefore a reduced demand for glucose. This intern can increase body weight and serum cytokinin levels. Also, with short wavelength blue light, there is an increase probability of cell aging and death. “It is suggested that this is partly due to 420–450 nm light, dominant in LEDs, being absorbed by porphyrin and the subsequent production of oxygen singlets driving inflammation.” “Conversely, exposure to longer wavelengths is associated with increased mitochondrial membrane potential and increased concentration of mitochondrial complex proteins that have declined with ageing and disease. This in turn is associated with elevated ATP, reduced inflammation and extended average lifespan.“ So, for the love of mitochondria, get long-wavelength light! This can be done in many ways: -sunlight/daylight exposure (does not need to be direct sunlight) -fire light -incandescent light bulbs -LEDs that emit long-wavelength light (yes, LEDs CAN emit red and near-infrared, but most don’t)
2:56

SUPPLEMENTING YOUR WORK ENVIRONMENT WITH AN INCANDESCENT LIGHT BULB IMPROVES MITOCHONDRIAL FUNCTION! - A brand new (Jan 23th, 2026) paper published by Glen Jeffery and Edward Barrett demonstrates how adding a 60 W incandescent lamp to participants work desk dramatically improves color contrast, or a proxy for color vision. The intervention here is simply placing an incandescent lightbulb on the desk without direct irradiation on participants. And this is huge: “we have obtained significant balanced improvements in both the protan and tritan range. Previously, exposure to restricted experimental 670 nm resulted in improvements biased strongly in favour of only tritan function. Hence, exposure to full spectrum lighting results in a balanced pattern of improvement in visual performance.” The mechanism seems to be mitochondrial in nature. Short wavelength light, which is dominated in standard LED lighting, reduces mitochondrial function. There’s a reduction in mitochondria ATP production, and therefore a reduced demand for glucose. This intern can increase body weight and serum cytokinin levels. Also, with short wavelength blue light, there is an increase probability of cell aging and death. “It is suggested that this is partly due to 420–450 nm light, dominant in LEDs, being absorbed by porphyrin and the subsequent production of oxygen singlets driving inflammation.” “Conversely, exposure to longer wavelengths is associated with increased mitochondrial membrane potential and increased concentration of mitochondrial complex proteins that have declined with ageing and disease. This in turn is associated with elevated ATP, reduced inflammation and extended average lifespan.“ So, for the love of mitochondria, get long-wavelength light! This can be done in many ways: -sunlight/daylight exposure (does not need to be direct sunlight) -fire light -incandescent light bulbs -LEDs that emit long-wavelength light (yes, LEDs CAN emit red and near-infrared, but most don’t)

Jonathan Jarecki

65,208 просмотров • 6 месяцев назад

Collins: What you would say to maybe a single mom of two kids who's reading this report about how harmful these these cheap but very accessible foods are for her family and saying, well, you know, sometimes that's the best we can do. RFK JR: It's an illusion to think that processed food is cheap, because you end up paying for it with diabetes. You end up paying for it with auto immune dysregulation, with mitochondrial dysfunction, with inflammation, and you end up paying much higher costs in the long run.
2:23

Collins: What you would say to maybe a single mom of two kids who's reading this report about how harmful these these cheap but very accessible foods are for her family and saying, well, you know, sometimes that's the best we can do. RFK JR: It's an illusion to think that processed food is cheap, because you end up paying for it with diabetes. You end up paying for it with auto immune dysregulation, with mitochondrial dysfunction, with inflammation, and you end up paying much higher costs in the long run.

Acyn

453,296 просмотров • 1 год назад

Why Inflammation May Drive Alzheimer’s Disease | Dominic D’Agostino, Ph.D. (Metabolic Health Summit) This clip is from episode # 375 of The Drive which was released on 12/8/25. In the full episode, we cover: -Protein on ketogenic diets: Dom’s rationale for higher intake and muscle preservation -How ketosis may boost NAD, and why NAD supplements have fallen short so far -Emerging evidence for using a ketogenic diet to treat anorexia and other psychiatric disorders -Potential cognitive and performance benefits of ketone supplementation, and why pushing ketones too high can be dangerous Watch or listen (Ep. # 375) to the full episode on my website ( or your favorite podcast player.
1:39

Why Inflammation May Drive Alzheimer’s Disease | Dominic D’Agostino, Ph.D. (Metabolic Health Summit) This clip is from episode # 375 of The Drive which was released on 12/8/25. In the full episode, we cover: -Protein on ketogenic diets: Dom’s rationale for higher intake and muscle preservation -How ketosis may boost NAD, and why NAD supplements have fallen short so far -Emerging evidence for using a ketogenic diet to treat anorexia and other psychiatric disorders -Potential cognitive and performance benefits of ketone supplementation, and why pushing ketones too high can be dangerous Watch or listen (Ep. # 375) to the full episode on my website ( or your favorite podcast player.

Peter Attia

35,756 просмотров • 8 месяцев назад

I had Dr. Jaban Moore on my podcast! In my opinion one of the top integrative doctors out there. He works with people around the world on complex chronic illness: Lyme disease, mold toxicity, heavy metals, MCAS, long COVID and everything in between. We get into a ton. Why blood tests for heavy metals are almost completely useless, how your body adapts to toxins so well that your labs can look fine while you are actually very sick, why psych meds can still be sitting in your cells years after you stopped taking them, what it actually means when you react badly to magnesium or B vitamins, the energy budget framework and why high achievers can burn themselves out. Why living in a bubble and feeling okay is not the same as being healed (duh), how trauma and mold toxicity create the same internal loop that keeps your body stuck in fight or flight, what the neurotoxic loop is and why leaving a moldy house does not automatically stop the immune response. He’s an integrative doc I’d trust to treat patients properly and worth a listen.
1:18:02

I had Dr. Jaban Moore on my podcast! In my opinion one of the top integrative doctors out there. He works with people around the world on complex chronic illness: Lyme disease, mold toxicity, heavy metals, MCAS, long COVID and everything in between. We get into a ton. Why blood tests for heavy metals are almost completely useless, how your body adapts to toxins so well that your labs can look fine while you are actually very sick, why psych meds can still be sitting in your cells years after you stopped taking them, what it actually means when you react badly to magnesium or B vitamins, the energy budget framework and why high achievers can burn themselves out. Why living in a bubble and feeling okay is not the same as being healed (duh), how trauma and mold toxicity create the same internal loop that keeps your body stuck in fight or flight, what the neurotoxic loop is and why leaving a moldy house does not automatically stop the immune response. He’s an integrative doc I’d trust to treat patients properly and worth a listen.

Mikhaila Peterson

20,728 просмотров • 3 месяцев назад

Retatrutide forever, watch this (Spoiler alert science agrees) Here’s everything you need (it’s free!) Think of it like this… Biology is a building… Drugs are trying to fix one room Retatrutide handles everything… At the same time Most doctors and Instaexperts talk about it without actually understanding biology or what they're doing… 2023 Cell Metabolism proved retatrutide wasn’t just about weight loss… it rewires how cells process energy at the mitochondrial level 2021 Aging Cell showed glucagon signaling cranks up autophagy specifically in neurons and hepatocytes… brain cells and liver cells The cells that matter most for longevity 2023 Nature Metabolism proved weekly pulsatile signaling activates more downstream pathways than multiple weekly signaling Why? Because cells have memory Receptor sensitivity actually increases if you give the signal, then let it recover then signal again So weekly 0.1 mg? Actually more effective than microdosing 2-3x a week And here's the best part… At 0.1 mg weekly… no weight loss unless you have significant metabolic dysfunction but cells will upgrade mitochondria increase autophagy and reduce systemic inflammation Biology is aging more slowly FYI 2024 Nature Communications… they applied retatrutide to cancer cells and the cancer cells died Why? Because cancer cells are metabolically distinct from normal cells They rely on a different energy pathway the Warburg effect and bypass normal mitochondrial ATP production It’s a cancer predator, period The 2025 follow-up study showed existing tumors exposed to retatrutide had 67 % tumor shrinkage You're making biology hostile to cancer at the cellular level Do what you want to do… I’m here to help you Because I actually care Never Miss Dr Trevor Bachmeyer The Spartan
2:48

Retatrutide forever, watch this (Spoiler alert science agrees) Here’s everything you need (it’s free!) Think of it like this… Biology is a building… Drugs are trying to fix one room Retatrutide handles everything… At the same time Most doctors and Instaexperts talk about it without actually understanding biology or what they're doing… 2023 Cell Metabolism proved retatrutide wasn’t just about weight loss… it rewires how cells process energy at the mitochondrial level 2021 Aging Cell showed glucagon signaling cranks up autophagy specifically in neurons and hepatocytes… brain cells and liver cells The cells that matter most for longevity 2023 Nature Metabolism proved weekly pulsatile signaling activates more downstream pathways than multiple weekly signaling Why? Because cells have memory Receptor sensitivity actually increases if you give the signal, then let it recover then signal again So weekly 0.1 mg? Actually more effective than microdosing 2-3x a week And here's the best part… At 0.1 mg weekly… no weight loss unless you have significant metabolic dysfunction but cells will upgrade mitochondria increase autophagy and reduce systemic inflammation Biology is aging more slowly FYI 2024 Nature Communications… they applied retatrutide to cancer cells and the cancer cells died Why? Because cancer cells are metabolically distinct from normal cells They rely on a different energy pathway the Warburg effect and bypass normal mitochondrial ATP production It’s a cancer predator, period The 2025 follow-up study showed existing tumors exposed to retatrutide had 67 % tumor shrinkage You're making biology hostile to cancer at the cellular level Do what you want to do… I’m here to help you Because I actually care Never Miss Dr Trevor Bachmeyer The Spartan

Dr Trevor Bachmeyer

24,053 просмотров • 29 дней назад

5 core principles behind every successful diet | Peter Attia, M.D. This trailer is from “Ask Me Anything” episode # 75 (Ep. # 364) of The Drive which was released on 9/15/25. In the full episode, I cover: -Why diet debates are so polarizing and confusing—and a clear framework to cut through the noise -The real strengths and hidden pitfalls of ketogenic, carnivore, vegan, and Mediterranean diets -How to know if your diet is actually working with lab tests, body scans, and glucose monitoring -Why flexibility and adherence matter more than chasing the “perfect” diet -More This AMA episode (Ep. # 364) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.
1:23

5 core principles behind every successful diet | Peter Attia, M.D. This trailer is from “Ask Me Anything” episode # 75 (Ep. # 364) of The Drive which was released on 9/15/25. In the full episode, I cover: -Why diet debates are so polarizing and confusing—and a clear framework to cut through the noise -The real strengths and hidden pitfalls of ketogenic, carnivore, vegan, and Mediterranean diets -How to know if your diet is actually working with lab tests, body scans, and glucose monitoring -Why flexibility and adherence matter more than chasing the “perfect” diet -More This AMA episode (Ep. # 364) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

Peter Attia

41,349 просмотров • 11 месяцев назад

🧬 Why does ☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 say “Food doesn’t matter”? Imagine a solar-powered battery: Sunlight charges the battery. Water holds the charge. Magnetism organizes the charge. The battery powers the engine. The engine burns the fuel. Food is a fuel. If the battery is empty or the wiring is broken, the engine cannot burn the fuel correctly. Changing the fuel will not fix the battery. Fix the battery first, then any fuel can be used. 🤔 Understanding 🔥 1. The ENGINE comes before the FUEL If the mitochondrial engine is not working, the fuel doesn’t matter. Why? Because in our modern world, we are trying to fix a physics problem with food ideology. It will never work. Mitochondria are the engine that burns the fuel. If the engine is damaged, all fuels become incomplete, misinterpreted, or even toxic. 👎🏻Most people today have engines damaged by: blue light EMFs indoor living poor redox lack of DHA no morning sunlight circadian mismatch ❌When the engine is broken, these things happen: electrons cannot move efficiently ATP production slows inflammation rises ROS becomes uncontrolled hormones lose coherence fasting becomes stressful diets fail again and again Food does not fix any of this. ☀️ 2. LIGHT controls metabolism more deeply than any diet ever could Jack’s central point for 15 years: “Food is seasonal information. Light is the master instruction.” Morning sunlight programs: dopamine cortisol melatonin leptin mitochondrial timing thyroid signaling This means two people on the same diet can have completely different results depending on their light environment. Example: Someone living indoors under LEDs with low redox tries carnivore. They struggle. Someone living by the ocean with daily sunrise exposure builds strong redox. Carnivore works for them Keto works Carbs work seasonally Fasting works The diet didn’t change. The redox did. Diet is just light in disguise. 🌊 3. Mitochondria run on ELECTRONS, not on food quantity Jack always says: “You don’t need more supplements. You need more electrons.” Food is only an electron donor. But electrons only work when the biology is prepared to receive them in the same environment nature designed. The key factors that prepare the system are: DHA in cell membranes structured water created by sunlight a magnetic field that aligns proton flow circadian signals that control timing cold exposure that increases electron efficiency minimal blue light at night When these conditions are damaged: Electrons get stuck. Energy drops. Inflammation rises. Hormones lose rhythm. Detoxification breaks. Again: diet never fixes the foundation. 🧠 4. Why diet “gurus” are always fighting, and always missing the point. Carnivore gurus… Low-carb communities… Metabolic bros… Vegan influencers… Mediterranean… All of them fight about the fuel while ignoring the engine. It’s like watching the mechanics scream about gasoline quality while the engine has: no oil no spark plugs a dead battery Jack’s message is brutally simple: “Fix the mitochondrial environment first, and most diets will begin to work.” Without fixing the environment, no diet can save you. 🐟 5. Why DHA is the diet Kruse actually cares about. DHA is the molecule that lets sunlight become a direct electrical current inside your cell membranes. DHA is the antenna. If the antenna is broken, the light signal becomes distorted. Every metabolic pathway fails. This is why: “A vegan in Norway is committing mitochondrial suicide.” “Food is a distraction. Sunlight is the real nutrient.” DHA + sunlight is the diet nature designed for humans. DHA is an antenna. And an antenna is useless without the signal. 🔥 Remember Your mitochondrial redox decides your fate; not your diet. Your light environment writes the rules for your metabolism. Your DHA status determines how well you can read the rules. This is why all food fights are meaningless 🤭 The mitochondria decide everything long before the fork ever reaches your mouth.
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🧬 Why does ☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 say “Food doesn’t matter”? Imagine a solar-powered battery: Sunlight charges the battery. Water holds the charge. Magnetism organizes the charge. The battery powers the engine. The engine burns the fuel. Food is a fuel. If the battery is empty or the wiring is broken, the engine cannot burn the fuel correctly. Changing the fuel will not fix the battery. Fix the battery first, then any fuel can be used. 🤔 Understanding 🔥 1. The ENGINE comes before the FUEL If the mitochondrial engine is not working, the fuel doesn’t matter. Why? Because in our modern world, we are trying to fix a physics problem with food ideology. It will never work. Mitochondria are the engine that burns the fuel. If the engine is damaged, all fuels become incomplete, misinterpreted, or even toxic. 👎🏻Most people today have engines damaged by: blue light EMFs indoor living poor redox lack of DHA no morning sunlight circadian mismatch ❌When the engine is broken, these things happen: electrons cannot move efficiently ATP production slows inflammation rises ROS becomes uncontrolled hormones lose coherence fasting becomes stressful diets fail again and again Food does not fix any of this. ☀️ 2. LIGHT controls metabolism more deeply than any diet ever could Jack’s central point for 15 years: “Food is seasonal information. Light is the master instruction.” Morning sunlight programs: dopamine cortisol melatonin leptin mitochondrial timing thyroid signaling This means two people on the same diet can have completely different results depending on their light environment. Example: Someone living indoors under LEDs with low redox tries carnivore. They struggle. Someone living by the ocean with daily sunrise exposure builds strong redox. Carnivore works for them Keto works Carbs work seasonally Fasting works The diet didn’t change. The redox did. Diet is just light in disguise. 🌊 3. Mitochondria run on ELECTRONS, not on food quantity Jack always says: “You don’t need more supplements. You need more electrons.” Food is only an electron donor. But electrons only work when the biology is prepared to receive them in the same environment nature designed. The key factors that prepare the system are: DHA in cell membranes structured water created by sunlight a magnetic field that aligns proton flow circadian signals that control timing cold exposure that increases electron efficiency minimal blue light at night When these conditions are damaged: Electrons get stuck. Energy drops. Inflammation rises. Hormones lose rhythm. Detoxification breaks. Again: diet never fixes the foundation. 🧠 4. Why diet “gurus” are always fighting, and always missing the point. Carnivore gurus… Low-carb communities… Metabolic bros… Vegan influencers… Mediterranean… All of them fight about the fuel while ignoring the engine. It’s like watching the mechanics scream about gasoline quality while the engine has: no oil no spark plugs a dead battery Jack’s message is brutally simple: “Fix the mitochondrial environment first, and most diets will begin to work.” Without fixing the environment, no diet can save you. 🐟 5. Why DHA is the diet Kruse actually cares about. DHA is the molecule that lets sunlight become a direct electrical current inside your cell membranes. DHA is the antenna. If the antenna is broken, the light signal becomes distorted. Every metabolic pathway fails. This is why: “A vegan in Norway is committing mitochondrial suicide.” “Food is a distraction. Sunlight is the real nutrient.” DHA + sunlight is the diet nature designed for humans. DHA is an antenna. And an antenna is useless without the signal. 🔥 Remember Your mitochondrial redox decides your fate; not your diet. Your light environment writes the rules for your metabolism. Your DHA status determines how well you can read the rules. This is why all food fights are meaningless 🤭 The mitochondria decide everything long before the fork ever reaches your mouth.

Light Me Away ☀️

42,199 просмотров • 8 месяцев назад

How much control do we actually have over how we age?? David Sinclair has spent decades studying the biology of ageing, and what actually drives it at a cellular level. David is a professor of genetics at Harvard Medical School and one of the leading researchers in the field of ageing. His work focuses on why our bodies decline over time and what influences that process. He’s not talking about extreme interventions or unrealistic outcomes, but he’s focused on what the science actually says, and what we can influence today. A lot of what we believe about ageing feels fixed. That it’s just time passing and that decline is inevitable. But David challenges that by explaining what’s happening underneath it all.
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How much control do we actually have over how we age?? David Sinclair has spent decades studying the biology of ageing, and what actually drives it at a cellular level. David is a professor of genetics at Harvard Medical School and one of the leading researchers in the field of ageing. His work focuses on why our bodies decline over time and what influences that process. He’s not talking about extreme interventions or unrealistic outcomes, but he’s focused on what the science actually says, and what we can influence today. A lot of what we believe about ageing feels fixed. That it’s just time passing and that decline is inevitable. But David challenges that by explaining what’s happening underneath it all.

Steven Bartlett

67,272 просмотров • 5 месяцев назад