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In 2025 AI coded full bacteriophage genomes that work better than anything found in nature. And crushed top virologists in a test of lab troubleshooting – beating human specialists in their area of expertise 45% to 22%. What could go wrong? But destroying the 'tacit knowledge' barrier to bioweapons... show more
10,505 görüntüleme • 3 ay önce •via X (Twitter)
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Convention wisdom is that bioweapons are humanity's greatest weakness – 100x cheaper to make than to defend against. Andrew Snyder-Beattie thinks conventional wisdom is likely wrong. He has a plan cheap enough to do without government. Useful even in worst case scenarios like mirror bacteria. Effective enough to save most people. In one of my all-time fav interviews he lays out a low-tech 4-step approach developed by his research team at Open Philanthropy, to fix a problem most have thought unsolvable. ASB is hiring for many roles in this project from logistics to biotech to manufacturing, and has $100s millions to deploy. Enjoy, links below! 2:10 How bad it could get 9:19 The worst-case scenario: mirror bacteria 18:14 Why low-tech 25:30 Prevention 31:21 The “4 pillars” plan 33:09 ASB is hiring now to make this happen 35:11 Everyone was wrong: biorisks are defence dominant 40:23 Pillar 1: Lungs 55:53 Pillar 2: Biohardening 1:15:19 Pillar 3: Detection 1:28:40 Pillar 4: The wrench hypothesis 1:40:12 The plan's biggest weaknesses 1:44:44 Would chaos make this impossible to pull off? 1:51:50 Would rogue AI make bioweapons? 1:57:57 We can feed the world even if all the plants die 2:07:03 Could a bioweapon make the Earth uninhabitable? 2:09:35 What ASB is hiring for 2:30:27 How to protect yourself and your family (On the 80,000 Hours Podcast, available anywhere you get podcasts.)
Rob Wiblin
168,670 görüntüleme • 9 ay önce


