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Linear CEO Karri Saarinen says some companies are using "friction forms" to help engineers break through bureaucracy and get new AI tools approved faster: "There are a lot of companies where employees ask, 'Can I use agents?' and they say, 'No, you can’t.' And they don’t really have a...

15,799 просмотров • 4 месяцев назад •via X (Twitter)

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Marc Andreessen on the 3 things he looks for when investing in a startup The first thing Marc Andreesen looks for is a big market: “Is there a big existing market that you think you can go after and displace incumbents? Or do you believe there will be a new market that will be big?” The second thing he looks for is a 10x better product: “Is there a fundamental technology or economic change that justifies a new company? And the way I always think about that is: Is there a 10x change happening in the technology landscape? Is something 10x faster, 10x cheaper, or 10x better? If it’s not 10x, we as both VCs and entrepreneurs have to ask ourselves if it’s really worth doing because it’s really hard to start new companies . . . Existing companies are usually pretty good at what they do. So for a new company to exist, it has to bring a product to market that’s so much better than what exists that it punches through the status quo.” The third is the team: “Is the team outstanding? . . . You want to have a founding team of complementary skillsets. You want to have at least one super strong technologist — quite possibly more than one. Some of the best startups are actually more than one founding technologist. And then it often helps to have someone who is a marketing or salesperson who has a really good understanding of business.” Marc believes that you need all three of these, but if you’re going to compromise on one of those as an investor, it should be the product: “A great market is a lot easier to make up for with iterative product execution. The problem with a poor or small market is that even if you do a good job on the product, there just aren’t that many customers so it’s hard to ever get big and people get demoralized . . . And then we evaluate the team of a startup by its ability to get into a big market with a good product.”

Startup Archive

17,333 просмотров • 6 месяцев назад

Marc Andreessen explains the 3 Necessities for Start-up Success: "The general criteria for a successful high-tech startup, in my view, you see different sort of rules of thumb from different people. But the three big things you always come back to are, is there a big market? And by the way, that comes in two parts. Is there a big existing market that you think you can go after and sort of displace incumbents or do you believe there will be a new market that will be big? So big market. Is there a fundamental technology or economic change that causes you to basically justify having a new company? And that's really important. And the way I always think about that is, is there a 10X change happening in the technology landscape? Is something 10X faster or 10X cheaper or 10X better? And if it's not 10X, we as both VCs and entrepreneurs, we really have to ask ourselves like, is it really worth doing? Because it's really hard. I mean, it's really hard to start new companies. new companies generally shouldn't exist. Existing companies are usually pretty good at what they do. And so for a new company to exist, it not only has to like come in and go into business and bring a product to market, but it has to bring a product to market that's so much better than what already exists that it punches through the sort of status quo. And most customers in most markets are pretty happy buying from the current suppliers and so there has to be a real kind of edge on the thing and we look for that in either a technology change, usually a technology change or an economic change. which are often the same thing. And then the third is team. Is the team outstanding? And if you think about this as an entrepreneur, it becomes a question of the founding team. Some companies are solo founders and they can work, but generally most of us, like myself, we're human beings, we're mortal. You want to have a founding team of complementary skill sets. And so you want to have at least one super strong technologist, quite possibly more than one. Some of the best startups are actually more than one founding technologist and then it often helps to have somebody who's like a product or who's a market or sales person or has a sort of really good understanding of business on the team, certainly helps a lot. And so we sort of look at market, product, and team. And the reality is you need all three. I would say, interestingly, if you're going to compromise as an investor, if we're going to compromise on one of those, it would actually be the product. And the reason I say that is because a great market is a lot easier to make up for with iterative product execution than a poor market. Because the problem with a poor market, a small market, is even if you do a great job on the product, there just aren't that many customers. It's hard to ever get big."

Founder Mode

39,005 просмотров • 6 месяцев назад

$ABCL CEO Carl Hansen explains the net negative overall value creation in biotech and how AbCellera plans to beat it: “I really think it can be beat because there’s a lot of mistakes that get made in where you allocate capital.” “If you’re a biotech and you start a company on a drug, and you go public and have a drug, and now the data is looking not that great, you just keep running that drug. … Because if you quit that drug, the company is done.” “So, because you’re so concentrated on one thing, you end up having blinders. It’s like a cult of a molecule. And even a real, practical, capital access problem that makes you continue to move things forward” ______________________________________ “Another problem is that many of the drugs that get started, get started by people who don’t understand the competitive or commercial landscape and have no intent of ever actually manufacturing it. … Because they know someone else is going to buy it. So then their framework is not ‘Am I making a drug that’s going to make a difference for people?’ The framework is ‘Can I make something that I think someone will take off my hands?’ And that happens a lot.” “There are many acquisitions where a big pharma company spends $10B, $20B, and it’s a complete bust. So really no value is generated for patients but someone was able to get a good exit on that because they anticipated what someone would want. And a lot of decision making gets done like that”. _______________________________________ “I’m not saying that we have this all solved. But what we’re trying to do is create a framework where we are able to take many bets so that we don’t fall in love with anything, or we don’t have to fall in love with anything. … And then always hold up very explicitly what we know and what we don’t know along the dimensions that matter. The dimensions that matter are - Will it work? That’s a science. - When it gets where will people care? - Is it differentiated? - Does it solve a big problem? In order to get it there, is there a path with our resources and expertise that would allow us to see it through?” “When you start to hold things up like that, you start to see where the mistakes are, where the uncertainties are, and you can be more rational in deciding ‘We’re going to run it to here because we get to flip the card and if the card goes the wrong way we’re going to kill it because we’ve got something else behind it.’” “I do think that if done right, and if you can pick the right opportunities, the success rate can be well higher than an order of magnitude better. … And there are examples of this… companies I’ve mentioned, you know, Regeneron, their success rate is at least 10x the industry in bringing programs forward and getting them approved. … So it’s… you can do it better that way”

Jack Prescott

27,317 просмотров • 15 дней назад

Steve Jobs on what separates the successful founders from unsuccessful ones Steve is asked what the factors of success and common pitfalls are for young entrepreneurs. He responds: “I get asked this a lot, and I have a pretty standard answer. A lot of people come to me and say, ‘I want to be an entrepreneur.’ And I go, ‘Oh, that’s great, what’s your idea?’ And they say they don’t have one yet. And I say I think you should go get a job as a busboy or something until you find something you’re really passionate about, because it’s a lot of work.” Steve continues: “I’m convinced that about half of what separates the successful entrepreneurs from the non-successful ones is pure perseverance. It is so hard. You pour so much of your life into this thing, and there are such rough moments in time that most people give up. I don’t blame them. It’s really tough, and it consumes your life. I mean, if you’ve got a family and you’re in the early days of a company, I can’t imagine how one could do it. I’m sure it’s been done, but it’s rough because it’s pretty much an 18-hour-a-day job, 7 days a week for a while. So unless you have a lot of passion about this, you’re not going to survive. You’re going to give it up.” He concludes: “You’ve got to have an idea or a problem or a wrong that you want to right that you’re passionate about. Otherwise, you’re not going to have the perseverance to stick it through. And I think that’s half the battle right there.”

Startup Archive

80,791 просмотров • 9 месяцев назад

Nick Saban was asked a question after practice once. His response was 70 seconds of gold on what it takes to be successful in life. Here’s Saban on the Illusion of Choice: “These guys, they all think they have this illusion of choice. Like I can do whatever I want to do. “You have a younger generation now that doesn’t always get told no. They don’t get told this is exactly how you need to do it. So they have this illusion that they have all these choices. “But the fact of the matter is, if you want to be good you don’t really have a lot of choices. It takes what it takes. You have to do what you have to do to be successful. “You have to make the choices and decisions to have the discipline and the focus to the process of what you need to do to accomplish your goals. “All these guys that think they have a lot of choices are sadly mistaken. As we all have done with our own children, they learn these lessons of life as they get older. “Sometimes the best way to learn is from the mistakes you make, even though we all hate to see them have to make them, and we don’t condone it when they do.” – I’ve studied Saban for 12+ years, and the Illusion of Choice is one of the most powerful concepts I’ve come across. Some key takeaways: 1. Excellence has a price. We can complain about that, but it’s a fact of life. 2. Most people don’t want to pay that price. They just haven’t admitted it to themselves. 3. Saying you want to be excellent is easy. Becoming excellent is hard. 4. There may not be one way to become great, but there are very few. And they all have discipline and consistency in common. 5. Every action we take is a choice. We’re choosing to make progress, or we’re not. 6. The formula for becoming successful: Your Daily Choices x Time. It’s simple, but we make it complicated. 7. Sometimes we learn more by making the wrong choices. Reflect on them, pull out the lessons and move on. 8. You have to choose what you do every day. Don’t follow your feelings. Choose to do what will make you better. 9. There are no long-term hacks. It takes what it takes. ||| Hope this is helpful. Follow me Teddy Mitrosilis for more writing. I also write a weekly newsletter on the process of improvement →

Teddy Mitrosilis

4,059,076 просмотров • 2 лет назад

I'm up late with the rest of you building AI agents with the new AI browser from Genspark. We can see where this is all going: a new kind of operating system -- one that is very different than the Microsoft centric way that I've been working for 20 years. There are several things that these new agentic browsers bring to you: 1. They let you change how you browse. With an old browser like Google Chrome, you go to your email, Facebook, or X. 2. With these new browsers, you tell it where to go and what to do for you. 3. It can even build software for you. At the end of this video, I have it building me a little YouTube uploading utility, which is very helpful. 4. They have a ton of "applications" built in. Think of it as a new kind of office suite. Docs. Spreadsheets. Slide decks. And much more. All built with AI, not bolted on the side like with Microsoft's Office. 5. They have AI models built "underneath" so you can work privately and cheaply. There’s a lot of new choices you have to make with browsers like this. I’ve been playing with a bunch of them. Some have better user interfaces than others. Some have different versions, slide components, or applications. The reason I like Genspark is because they ship so fast. I’ve been watching this company since its very beginnings, and every week they ship new things. Just yesterday, they shipped a new photo editing feature for my iPhone. I upload a photo and then I can just talk to it and edit it with my voice. It's really cool. I try to reward companies that ship at such a fast rate and that are shipping innovation that improves our lives. It's not that I'm going to stop using Google Chrome. My whole life has been there for, I don't know, almost 20 years now. This is a different way of working and it gives me a space to run my AI tasks that's different than Google Chrome. I run them side by side. One doing old stuff, one doing new stuff. I can keep using Google Chrome for my old stuff, like my email and my calendar. And I use GenSpark or one of the new AI browsers to do new AI-centric things. All sorts of new things that these new agentic browsers open up! Have you tried it, or one of the other new ones yet? How has it changed your work? It takes a little time to get used to AI-centric ways of doing things. Pretend your browser is a team of interns. Give them a task, in this case I said "help me upload my videos to YouTube." You might be shocked at what Genspark does to improve your life. I am everytime I use it. Give it a try and let me know what you think! Oh, and I used another little tool to "write" this post. Typeless -- I push a button and talk and it writes. With fewer typos than I usually type in, to boot. It works great with Genspark's new browser too. Download it here:

Robert Scoble

70,991 просмотров • 10 месяцев назад

Nawiwi: "Whether to renew the contract or not, we already had an official discussion about a month ago with both the parents coming to talk to me and the team. We talked and seemed to understand each other, and the artist and parents said they would give a response in 2-3 days, but more than a month has passed now. No matter how many times I ask, there is no answer, and it’s not clear. This is what we got, so we don’t know either. I have had staff follow up with the artist many times asking what the response is. What the plan is, what was agreed on. They were supposed to give a summary back because we already gave the solution and they wanted to propose something. We wanted to listen but they just disappeared. From three days to more than a month now, no matter how many times I ask, no response. Probably not coming, probably busy lately. I see them just playing fitness and liking all the fans’ posts first. So, fan clubs when you say you want that person to have work, you have to see if they actually want to do it, like it, or just have to endure it. You have to see who they really are, uh... yeah. You have to see the reality too... We are ready to support and open opportunities in every case. Even if you say how many million per year you want, write it down and we will arrange it for you. If you don’t trust us, go trust someone else, and it will turn out like this. But we are not saying it’s not everyone’s personal right. We have done our job perfectly, called the parents to a meeting, made a contract agreement to give feedback to each other, but there was no feedback, so it’s over. Bye." 🤣🤣🤣Bruh all of this over someone you said is talentless, disrespectful, controversial, that nobody wants, that's disrespectful to fans and employers? All of this over them?

Mr Jiggle Mc-butt

295,799 просмотров • 3 месяцев назад

Elon Musk: Radical deregulation is necessary in Europe. If that means leaving the EU, it means leaving the EU. “Europe is overregulated. There are too many rules and regulations that make it very difficult to create a company and do too much to protect large companies at the expense of small to medium-sized companies. So, the net result is you have a bunch of very small companies in Europe and then it's small number of very large companies, but then not much in the middle. So, there needs to be a way to go from being a small company if you're making great products and services to be able to scale to ultimately become a big company. But you have effectively regulatory capture by the large corporations in Europe. They don't really want to reduce the regulatory burden and they like the fact that the regulations effectively protect their duopolies or monopolies in some cases. So really, I think it's up to the government to say no, we have to foster small companies and allow them to compete and reduce regulations because the regulatory situation in Europe is stifling and Brussels is amplifying that greatly. So you have both the local regulations, the country regulations and then you have the EU regulations. There's so many regulations in Europe, it makes it extremely difficult to start a company and be successful. So, I think radical deregulation is necessary in Europe. And if that means leaving the EU, it means leaving the EU.” From: Interview with Matteo Salvini, April 5, 2025

ELON CLIPS

29,270 просмотров • 1 год назад

Is Traditional Software Engineering Dead? “Does this mean that traditional software engineering is dead? Absolutely not. Software engineers—even the ones who are not necessarily tuning or training AI models—these are now among the most leveraged people on earth. Sure, the guys who are training and tuning models are even more leveraged because they’re building the tool set that software engineers are using. But software engineers still have two massive advantages on you. First, they think in code, so they actually know what’s going on underneath. And all abstractions are leaky. So when you have a computer programming for you—when you have Claude Code or equivalent programming for you—it’s going to make mistakes. It’s going to have bugs. It’s going to have suboptimal architecture. So it’s not going to be quite right. And someone who understands what’s going on underneath will be able to plug the leaks as they occur. So if you want to build a well-architected application, if you want to be able to even specify a well-architected application, if you want to be able to make it run at high performance, if you want it to do its best, if you want to catch the bugs early, then you’re going to want to have a software engineering background. The traditional software engineer is going to be able to use these tools much better. And there are still many kinds of problems in software engineering that are out of scope for these AI programs today. The easiest way to think about those is problems that are outside of their data distribution. For example, if they need to do a binary sort or reverse a linked list, they’ve seen countless examples of that, so they’re extremely good at it. But when you start getting out of their domain—where you have to write very high-performance code, when you’re running on architectures that are novel or brand new, when you’re actually creating new things or solving new problems, then you still need to get in there and hand code it. At least until either there are so many of those examples that new models can be trained on them, or until these models can sufficiently reason at even higher levels of abstraction and crack it on their own… And remember: there is no demand for average. The average app—nobody wants it, at least as long as it’s not filling some niche that is filled by a superior app. The app that is better will win essentially a hundred percent of the market. Maybe there’s some small percentage that will bleed off to the second-best app because it does some little niche feature better than the main app, or it’s cheaper, or something of the sort. But generally speaking, people only want the best of anything. So the bad news is there’s no point in being number two or number three—like in the famous Glengarry Glen Ross scene where Alec Baldwin says, “First place gets a Cadillac Eldorado, second place gets a set of steak knives, and third place you’re fired.” That’s absolutely true in these winner-take-all markets. That’s the bad news: You have to be the best at something if you want to win. However, the set of things you can be best at is infinite. You can always find some niche that is perfect for you, and you can be the best at that thing. This goes back to an old tweet of mine where I said, “Become the best in the world at what you do. Keep redefining what you do until this is true.” And I think that still applies in this age of AI.”

Naval

853,816 просмотров • 5 месяцев назад

Whitney Webb "It sucks to find out that the mob runs the world... [so] do you want to say, screw you guys, we're going to... get off your... slave plantation?... [because] we can't really keep losing money and rights without being so deep in a hole that we can't... climb out" This clip of Webb (Whitney Webb), a contributing editor of Unlimited Hangout and author of One Nation Under Blackmail, is taken from an interview with Peter McCormack (The Peter McCormack Show) posted to YouTube on September 4, 2025. -----------------Partial transcription of clip-------------- "It's not just about burning it down, it's about putting something better in its place. Of course. And so I think the solutions there, you know, some people are like, oh, Whitney, your work is so demoralizing. Well, I'm like, yeah, it sucks to find out that the mob runs the world, you know, but the question is, or do you just want to let them keep running it because it bums you out, or do you want to say, screw you guys, we're going to build something else and get off your, you know, slave plantation? "And I am in the group of, I would like to build something else. I have three kids. I do not want them living in a world run by the mob. So what are you going to do about it? I mean, it starts locally, it starts with your community, because that's where we can actually affect change. Voting for left or right, blue or red. I mean, it's just this ping pong thing where nothing fundamental is changing. "And so to affect that change, we have to do it ourselves. And you think this would be a core American value? Individualism, individual responsibility. But a lot of people just don't care. And so, you know, that sucks. But I think those of us that do care need, to take steps to be as independent from the system as possible. Because every so often, this predator class, they do wealth transfers or they orchestrate and manufacture events and they make a big grab, not just for our money, but for our rights. And we're at the point where we can't really keep losing money and rights without being so deep in a hole that we can't climb ourself out. Can't climb out. "So what, what should we do before that happens? There is an important window of time to do something about it in our local community and for our families and our friends and our neighbors. And we have to do something because if we don't and that thing happens. Oh, well, I watched all these podcasts and learned about how corrupt everything is. But, you know, and I think they spend a lot of time trying to keep us distracted on all sorts of things and sucked into things that don't matter. So that we just don't give them the finger, basically. And that's what we really need to do."

Sense Receptor

46,951 просмотров • 11 месяцев назад