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Metabolic dysfunction rarely makes itself known until late in the process. Long before a diagnosis of type 2 diabetes, the body may already be struggling to store and access fuel efficiently. This guide distills the most important insights from science and clinical practice to help you identify, prevent, and... show more

Peter Attia

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42,281 次观看 • 8 个月前 •via X (Twitter)

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Erectile dysfunction precedes cardiovascular disease in many men because both conditions share the same upstream mechanism: endothelial dysfunction and impaired nitric oxide signaling. Penile vasculature is smaller in diameter than coronary vasculature and reflects vascular compromise earlier. This means erectile function is one of the most accurate early indicators of cardiovascular risk available, and most men are never told that. In this episode, Dr. Amy Pearlman covers the vascular and metabolic interface behind erectile dysfunction, how to interpret testosterone labs correctly, why cardiorespiratory fitness rivals pharmacological intervention for erectile function, and what clinical tools exist that most urologists are never trained to prescribe.

Erectile dysfunction precedes cardiovascular disease in many men because both conditions share the same upstream mechanism: endothelial dysfunction and impaired nitric oxide signaling. Penile vasculature is smaller in diameter than coronary vasculature and reflects vascular compromise earlier. This means erectile function is one of the most accurate early indicators of cardiovascular risk available, and most men are never told that. In this episode, Dr. Amy Pearlman covers the vascular and metabolic interface behind erectile dysfunction, how to interpret testosterone labs correctly, why cardiorespiratory fitness rivals pharmacological intervention for erectile function, and what clinical tools exist that most urologists are never trained to prescribe.

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Drinking 2-3 cups of coffee each day can cut your risk of type 2 diabetes by up to 60% Coffee’s caffeine and chlorogenic acids flip on AMPK, the cellular “fuel-use” switch that ramps up fat-burning and glucose uptake while dialing down growth pathways Though coffee may briefly raise blood sugar, its long-term effect dramatically enhances glucose control and metabolic health Regular coffee intake (2–3 cups/day) consistently improves insulin responsiveness, reduces triglyceride levels, and protects against metabolic syndrome

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According to metabolic scientist, Ben Bikman, the earliest treatment for type 1 diabetes before insulin therapy, was an almost carnivore diet because it was the best way to stabilize blood glucose levels. Today most are told to just eat what they want & cover it with insulin.

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56,011 次观看 • 1 年前

How to ACTUALLY reverse Insulin Resistance That frustrating diagnosis of insulin resistance means the old rulebook for your body is obsolete. What once worked to manage your weight no longer applies. The good news? The new playbook for metabolic recovery doesn’t demand superhuman willpower. As Dr. Annette Bosworth (Dr. Boz) clarifies, reversing insulin resistance hinges on three fundamental shifts. First, track insulin, not calories. The primary lever is your insulin response, not energy units. Carbohydrates trigger the most significant insulin spike, protein a moderate one, and fat the most negligible. In a low-insulin state, dietary fat becomes a powerful metabolic fuel. The directive: embrace fat and restrict carbs to under 20 grams daily. Second, don't eat after dark. The timing of your fat-based meals is critical. Consuming food after sunset carries a heavier metabolic penalty for those with insulin resistance. The golden rule: lengthen the interval between your last bite and bedtime to optimize next-day insulin sensitivity. Third, "measure it if you want to change it." Since you can't easily test insulin directly, Dr. Boz recommends tracking its two most controlled molecules: glucose and ketones. Her innovative "Dr. Boz Ratio" (Glucose ÷ Ketones) serves as a powerful proxy. A lower ratio signals lower insulin, and the ideal time for this measurement is first thing upon waking. The path to reversing insulin resistance is not about deprivation, but about strategic, informed choices.

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I’m delighted to share that my friend and colleague Shere Ruano will be delivering an exclusive live webinar for our Metabolic Reset community. The title of the talk is Demystifying Breathwork: The Science of Breath and Metabolic Health. This webinar will explore the intricate workings of our nervous system and how our breath holds the key to managing stress and improving our metabolic health. During the second part of the webinar, Shere will lead us through a practical breathwork exercise that you'll be able to return to in the future as a valuable tool to help you manage daily stress. Shere is a stress reduction expert specialising in neurocardiology, nervous system regulation, and breathwork. She has a Master of Science in Cardiac Intensive Care and was one of the few senior specialist nurses in arrhythmia in the UK. Shere is highly sought after, lending her expertise to world-renowned clinics, NASDAQ company founders, investors, and Fortune 500 entrepreneurs. She speaks at conferences and delivers lectures in the UK and around the globe. To join Metabolic Reset and access this powerful breathwork session, visit the link in my bio. #MetabolicReset #onlineprogramme #ShereRuano #AseemMalhotra #KimPearson

I’m delighted to share that my friend and colleague Shere Ruano will be delivering an exclusive live webinar for our Metabolic Reset community. The title of the talk is Demystifying Breathwork: The Science of Breath and Metabolic Health. This webinar will explore the intricate workings of our nervous system and how our breath holds the key to managing stress and improving our metabolic health. During the second part of the webinar, Shere will lead us through a practical breathwork exercise that you'll be able to return to in the future as a valuable tool to help you manage daily stress. Shere is a stress reduction expert specialising in neurocardiology, nervous system regulation, and breathwork. She has a Master of Science in Cardiac Intensive Care and was one of the few senior specialist nurses in arrhythmia in the UK. Shere is highly sought after, lending her expertise to world-renowned clinics, NASDAQ company founders, investors, and Fortune 500 entrepreneurs. She speaks at conferences and delivers lectures in the UK and around the globe. To join Metabolic Reset and access this powerful breathwork session, visit the link in my bio. #MetabolicReset #onlineprogramme #ShereRuano #AseemMalhotra #KimPearson

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In this experiment, when a rat is exposed to a diet high in fats and sugars, similar to a typical North American diet, over time, its brain loses the ability to function clearly and is unable to navigate. These rats, once normal, now show signs of cognitive damage, unable to recall learned tasks even a day later. Could this be a clue to understanding Alzheimer's disease? Some researchers suggest that Alzheimer's might actually be a form of "diabetes of the brain," where metabolic dysfunction, similar to insulin resistance in the body, disrupts brain function and leads to cognitive decline.

The White Rabbit

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Dr. Benjamin Bikman drops a bombshell on high blood pressure, infertility, and erectile dysfunction that flips conventional medicine on its head: “High blood pressure is almost a guarantee of insulin resistance — the overwhelmingly most common cause.” He goes further: - Erectile dysfunction in men is often the earliest visible sign of insulin resistance — blood vessels can no longer dilate properly, making erections impossible. -PCOS (the leading cause of infertility in women) is at its core a metabolic disorder driven by insulin resistance — even in lean women who “look healthy” and don’t meet standard insulin resistance criteria. - Scratch beneath the surface, and insulin resistance is already present at the fat cell level — the true origin point. Science nugget: Insulin resistance begins in adipose (fat) tissue long before it shows up in blood tests. Chronically elevated insulin impairs nitric oxide production (needed for vasodilation), drives ovarian androgen excess in PCOS, and promotes vascular stiffness leading to hypertension and ED. Bottom line: Many “unexplained” conditions aren’t mysterious — they’re downstream effects of insulin resistance hiding in plain sight. What “healthy-looking” symptom or diagnosis in your life (or someone close) might actually be insulin resistance in disguise?

Dr. Benjamin Bikman drops a bombshell on high blood pressure, infertility, and erectile dysfunction that flips conventional medicine on its head: “High blood pressure is almost a guarantee of insulin resistance — the overwhelmingly most common cause.” He goes further: - Erectile dysfunction in men is often the earliest visible sign of insulin resistance — blood vessels can no longer dilate properly, making erections impossible. -PCOS (the leading cause of infertility in women) is at its core a metabolic disorder driven by insulin resistance — even in lean women who “look healthy” and don’t meet standard insulin resistance criteria. - Scratch beneath the surface, and insulin resistance is already present at the fat cell level — the true origin point. Science nugget: Insulin resistance begins in adipose (fat) tissue long before it shows up in blood tests. Chronically elevated insulin impairs nitric oxide production (needed for vasodilation), drives ovarian androgen excess in PCOS, and promotes vascular stiffness leading to hypertension and ED. Bottom line: Many “unexplained” conditions aren’t mysterious — they’re downstream effects of insulin resistance hiding in plain sight. What “healthy-looking” symptom or diagnosis in your life (or someone close) might actually be insulin resistance in disguise?

Camus

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Dr. Benjamin Bikman dropped a bombshell on the carnivore diet: “The metabolic improvements in people who go carnivore are absolutely mind-blowing… shocking how quickly they cut medications, feel better, look better, and move better. I’ve never seen anything comparable.” He admits the evidence is still emerging (mostly anecdotal and observational for now), but the real-world transformations he’s witnessed personally are “profound” and rapid—especially in people with serious metabolic issues. Science nugget: Carnivore eliminates virtually all dietary carbohydrates, forcing the body into deep ketosis and fat-adaptation. This often leads to dramatic drops in insulin, triglycerides, and inflammation markers within weeks, plus improved energy and reduced medication needs in insulin-resistant individuals (consistent with emerging low-carb/carnivore case series and metabolic health studies). Bikman’s take: The microbiome shifts dramatically (less diversity, fewer fiber-fermenters), but the metabolic dividends appear to outweigh that—for some people, at least. Carnivore skeptics vs. converts: Which camp are you in after hearing this?

Dr. Benjamin Bikman dropped a bombshell on the carnivore diet: “The metabolic improvements in people who go carnivore are absolutely mind-blowing… shocking how quickly they cut medications, feel better, look better, and move better. I’ve never seen anything comparable.” He admits the evidence is still emerging (mostly anecdotal and observational for now), but the real-world transformations he’s witnessed personally are “profound” and rapid—especially in people with serious metabolic issues. Science nugget: Carnivore eliminates virtually all dietary carbohydrates, forcing the body into deep ketosis and fat-adaptation. This often leads to dramatic drops in insulin, triglycerides, and inflammation markers within weeks, plus improved energy and reduced medication needs in insulin-resistant individuals (consistent with emerging low-carb/carnivore case series and metabolic health studies). Bikman’s take: The microbiome shifts dramatically (less diversity, fewer fiber-fermenters), but the metabolic dividends appear to outweigh that—for some people, at least. Carnivore skeptics vs. converts: Which camp are you in after hearing this?

Camus

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Dr. Pradip Jamnadas breaks it down simply for beginners: Glucose (sugar) in the bloodstream is toxic—it glycates everything (vessels, enzymes, hormones), aging you prematurely. Body's fix? Pancreas pumps insulin to shove glucose into cells (liver, muscle, everywhere). Eat carbs/starch every 2–3 hours? Insulin spikes repeatedly, never fully drops—leading to chronic high insulin (hyperinsulinemia). Result over years: - Insulin resistance (body needs more insulin for same effect) - Fatty liver & dangerous visceral belly fat (glucose → new fat around organs) - Silent metabolic destruction long before diabetes shows up (A1C normal, but damage underway) By diagnosis of diabetes? Often 10+ years of hidden high insulin + early coronary disease. This 6:05 clip is the clearest "insulin-glucose 101" I've seen—why constant grazing wrecks metabolism. Do you eat every few hours (snacks/meals)? Noticed belly fat creep despite "normal" weight? Tried reducing frequency (e.g., 2–3 meals/day) to lower insulin—any energy/weight shifts? What's one carb habit you're rethinking after this? Real experiences only—let's unpack how this shows up in life.

Dr. Pradip Jamnadas breaks it down simply for beginners: Glucose (sugar) in the bloodstream is toxic—it glycates everything (vessels, enzymes, hormones), aging you prematurely. Body's fix? Pancreas pumps insulin to shove glucose into cells (liver, muscle, everywhere). Eat carbs/starch every 2–3 hours? Insulin spikes repeatedly, never fully drops—leading to chronic high insulin (hyperinsulinemia). Result over years: - Insulin resistance (body needs more insulin for same effect) - Fatty liver & dangerous visceral belly fat (glucose → new fat around organs) - Silent metabolic destruction long before diabetes shows up (A1C normal, but damage underway) By diagnosis of diabetes? Often 10+ years of hidden high insulin + early coronary disease. This 6:05 clip is the clearest "insulin-glucose 101" I've seen—why constant grazing wrecks metabolism. Do you eat every few hours (snacks/meals)? Noticed belly fat creep despite "normal" weight? Tried reducing frequency (e.g., 2–3 meals/day) to lower insulin—any energy/weight shifts? What's one carb habit you're rethinking after this? Real experiences only—let's unpack how this shows up in life.

Camus

135,488 次观看 • 5 个月前

This is one of the most important movies you can watch at this very moment. Take the hour and learn about the Edward Bernays world you and I live in. From a VHS tape for you to see today. Be ready to understand how you and I have been played.

This is one of the most important movies you can watch at this very moment. Take the hour and learn about the Edward Bernays world you and I live in. From a VHS tape for you to see today. Be ready to understand how you and I have been played.

Brian Roemmele

287,653 次观看 • 1 年前

🚨BIG NEWS: $50M Investment to End America's Health Crisis!🚨 🔬I'm Andrew Koutnik, PhD in Nutrition, Metabolism & Diabetes—and a patient living with an irreversible chronic metabolic disease. Thrilled to advise the NEW Coalition for Metabolic Health, LAUNCHED to REVERSE our chronic disease epidemic! Our 4 BOLD objectives: 1⃣Push policy shifts for science-based nutrition guidelines, research, screenings & insurance. 2⃣Fund unbiased research to empower docs & public with real metabolic insights. 3⃣Educate providers, policymakers & YOU on metabolism's power to prevent/reverse disease. 4⃣Incorporate therapeutic nutrition in everyday care via key partnerships. 👉Join the revolution: #MetabolicHealth #ReverseChronicDisease Metabolic Mind Jan Ellison Baszucki Bret Scher, MD Dr. David Ludwig Dominic D'Agostino Benjamin Bikman DoctorTro

🚨BIG NEWS: $50M Investment to End America's Health Crisis!🚨 🔬I'm Andrew Koutnik, PhD in Nutrition, Metabolism & Diabetes—and a patient living with an irreversible chronic metabolic disease. Thrilled to advise the NEW Coalition for Metabolic Health, LAUNCHED to REVERSE our chronic disease epidemic! Our 4 BOLD objectives: 1⃣Push policy shifts for science-based nutrition guidelines, research, screenings & insurance. 2⃣Fund unbiased research to empower docs & public with real metabolic insights. 3⃣Educate providers, policymakers & YOU on metabolism's power to prevent/reverse disease. 4⃣Incorporate therapeutic nutrition in everyday care via key partnerships. 👉Join the revolution: #MetabolicHealth #ReverseChronicDisease Metabolic Mind Jan Ellison Baszucki Bret Scher, MD Dr. David Ludwig Dominic D'Agostino Benjamin Bikman DoctorTro

Andrew Koutnik, Ph.D.

29,638 次观看 • 10 个月前

BAN HQ Medical Committee presents Diabetic Awareness - World Diabetes Day 2024. World Diabetes Day is observed every year on November 14th, marking an important opportunity to raise awareness about diabetes and advocate for better prevention, diagnosis, and management of the disease. The day became an official United Nations (UN) day in 2006. This year’s theme, "Access to Diabetes Education," underscores the need for better information and resources to help prevent and manage diabetes effectively. The Medical Team of Brothers across Nigeria (BAN) worldwide is proud to recognize World Diabetes Day by supporting the established framework for diabetes education, which includes: 1. Learning and Knowledge Sharing. 2. Prevention. 3. Identification and Treatment. UNDERSTANDING DIABETES Diabetes is a disease that results from excess sugar in the blood, causing serious health problems over time. The Types of Diabetes: 1. Type 2 Diabetes: The most common form, accounting for about 90% of cases. It occurs when the body doesn’t use insulin effectively or doesn’t produce enough. 2. Type 1 Diabetes: An autoimmune condition, usually diagnosed in childhood, where the body cannot produce insulin. 3. Gestational Diabetes: Occurs during pregnancy and usually goes away after childbirth, but it increases the risk of developing type 2 diabetes later in life. 4. Prediabetes: A condition where blood sugar levels are higher than normal but not high enough to be considered type 2 diabetes. 1 in 3 adults has prediabetes, highlighting the need for early intervention and lifestyle changes. SYMPTOMS OF DIABETES The symptoms of diabetes vary, and some people (especially those with prediabetes, gestational diabetes, or type 2 diabetes) may not experience symptoms at all. In type 1 diabetes, symptoms usually appear quickly and are more severe. Common symptoms include: I. Increased thirst or urination II.Fatigue III. Blurry vision IV. Slow-healing sores or infections RISK FACTORS A variety of factors contribute to the risk of developing type 2 diabetes, including: Age and genetics, Lifestyle factors:, poor diet, lack of physical activity, and smoking increase the likelihood of developing diabetes. Social factors: Access to healthy food, healthcare, and safe spaces for exercise also play a significant role in managing and preventing diabetes. Race and Ethnicity: People from certain racial or ethnic backgrounds, including Black, Hispanic, American Indian, and Asian American populations, are at higher risk for type 2 diabetes. Discrimination and stigma: These factors can exacerbate the challenges faced by marginalized communities in managing diabetes. COMPLICATIONS When diabetes is not properly controlled, it can cause serious and even life-threatening complications, including Heart disease and strokes, Nerve damage (neuropathy), Kidney damage, Eye problems, Foot issues, Skin and mouth infections, Hearing loss, Memory issues, Depression and Anxiety. PREVENTION Preventing or delaying type 2 diabetes is possible through early lifestyle changes. The following strategies can help reduce the risk of developing diabetes: 1. Eat a Healthy Diet 2. Get Active 3. Maintain a Healthy Weight 4. Quit Smoking 5. Limit Alcohol Intake 6. Get Regular Checkups 7. Manage Stress 8. Sleep Well CONCLUSION World Diabetes Day is an important reminder of the growing global impact of diabetes and the urgent need for education, awareness, and action. This year’s theme highlights the critical need for better information and resources to prevent and manage the disease. By focusing on education, early detection, and lifestyle changes, we can work together to reduce the burden of diabetes and create a healthier future for all. #BANWorldwide, #BrothersAcrossNigeria #WorldDiabetesDay, #WDD2024, #DiabetesAwareness, #KnowYourNumbers, #DiabetesPrevention, #14November, #AccesstoDiabetesCare

BAN HQ Medical Committee presents Diabetic Awareness - World Diabetes Day 2024. World Diabetes Day is observed every year on November 14th, marking an important opportunity to raise awareness about diabetes and advocate for better prevention, diagnosis, and management of the disease. The day became an official United Nations (UN) day in 2006. This year’s theme, "Access to Diabetes Education," underscores the need for better information and resources to help prevent and manage diabetes effectively. The Medical Team of Brothers across Nigeria (BAN) worldwide is proud to recognize World Diabetes Day by supporting the established framework for diabetes education, which includes: 1. Learning and Knowledge Sharing. 2. Prevention. 3. Identification and Treatment. UNDERSTANDING DIABETES Diabetes is a disease that results from excess sugar in the blood, causing serious health problems over time. The Types of Diabetes: 1. Type 2 Diabetes: The most common form, accounting for about 90% of cases. It occurs when the body doesn’t use insulin effectively or doesn’t produce enough. 2. Type 1 Diabetes: An autoimmune condition, usually diagnosed in childhood, where the body cannot produce insulin. 3. Gestational Diabetes: Occurs during pregnancy and usually goes away after childbirth, but it increases the risk of developing type 2 diabetes later in life. 4. Prediabetes: A condition where blood sugar levels are higher than normal but not high enough to be considered type 2 diabetes. 1 in 3 adults has prediabetes, highlighting the need for early intervention and lifestyle changes. SYMPTOMS OF DIABETES The symptoms of diabetes vary, and some people (especially those with prediabetes, gestational diabetes, or type 2 diabetes) may not experience symptoms at all. In type 1 diabetes, symptoms usually appear quickly and are more severe. Common symptoms include: I. Increased thirst or urination II.Fatigue III. Blurry vision IV. Slow-healing sores or infections RISK FACTORS A variety of factors contribute to the risk of developing type 2 diabetes, including: Age and genetics, Lifestyle factors:, poor diet, lack of physical activity, and smoking increase the likelihood of developing diabetes. Social factors: Access to healthy food, healthcare, and safe spaces for exercise also play a significant role in managing and preventing diabetes. Race and Ethnicity: People from certain racial or ethnic backgrounds, including Black, Hispanic, American Indian, and Asian American populations, are at higher risk for type 2 diabetes. Discrimination and stigma: These factors can exacerbate the challenges faced by marginalized communities in managing diabetes. COMPLICATIONS When diabetes is not properly controlled, it can cause serious and even life-threatening complications, including Heart disease and strokes, Nerve damage (neuropathy), Kidney damage, Eye problems, Foot issues, Skin and mouth infections, Hearing loss, Memory issues, Depression and Anxiety. PREVENTION Preventing or delaying type 2 diabetes is possible through early lifestyle changes. The following strategies can help reduce the risk of developing diabetes: 1. Eat a Healthy Diet 2. Get Active 3. Maintain a Healthy Weight 4. Quit Smoking 5. Limit Alcohol Intake 6. Get Regular Checkups 7. Manage Stress 8. Sleep Well CONCLUSION World Diabetes Day is an important reminder of the growing global impact of diabetes and the urgent need for education, awareness, and action. This year’s theme highlights the critical need for better information and resources to prevent and manage the disease. By focusing on education, early detection, and lifestyle changes, we can work together to reduce the burden of diabetes and create a healthier future for all. #BANWorldwide, #BrothersAcrossNigeria #WorldDiabetesDay, #WDD2024, #DiabetesAwareness, #KnowYourNumbers, #DiabetesPrevention, #14November, #AccesstoDiabetesCare

Brothers Across Nigeria International

13,735 次观看 • 1 年前