MICROSCOPY. Making the invisible visible since 1590. (Yes, those little white balls are actually immune cells flowing through the tinniest blood vessels! Imaged painlessly, non-invasively through the skin)

@CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH While I have your attention, a fun science tidbit for the day is that blood cells always flow from your arterioles to your venules. So if you watch the direction of the blood cells circulating you will see the moment of venous return at the tip of the capillary!!!

@CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Did you know that in the incredible Invisible Illness TOPx @HHSGov Tech Sprint, our team is the only one with a core microscopy component? Please register to vote! or learn more at:

@CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH @HHSGov What Is at Stake: The highest-voted project in this track wins a $5K People's Choice Prize, and the Federal Judging Panel evaluates both public votes and on-page comments when awarding up to $2.6 in Phase 2 MVP prizes (including the $1,000,000 Grand Prize and $500,000 Runner-Up)!

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Macrophage are going to be a huge part of healing in the future. If we can tune them using bioelectricity, we can get them to regenerate instead of cause fibrosis at an injury site(like a salamander). I can’t wait for them to figure this out. The implications would be incredible!

Amazing! I am trying to work out how to use my microscope for iphone. Somehow I cannot see the capillaries on nailfold. Although I can see with my eyes that there is redness right next to the moons. Is there a trick? I am using just any immersion oil that I ordered. Should it be a certain type?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH See our quick guide here: One key thing is that you need to apply a clear oil at the nailfold to smooth the surface of the skin so that you can look through it with the microscope

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Still working on it, but I can see them!

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH People with Long Covid have messed up capillaries I have messed up ones on my fingers. What stimulates repair of those?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH We're loaded with such fragile intricacies.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Cool! What tissue is this?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Very cool.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Just amazing.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH This is so great! I remember reading the paper "Vascular Pathogenesis in Acute and Long COVID: Current Insights and Therapeutic Outlook" which suggested Nailfold Video Capillaroscopy for LC. And here it is!

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Cool, now count them!

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH We want to do more than count them! That's easy peasy.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Absolutely insane footage. Thanks for the share.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Through the findings in MAESTRO and others, have you managed to find any treatments for the root cause of these?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Working on it! MAESTRO was about measuring, now the next step is how do we then target treatments

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Is it looking any promising?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Very! But you have to tie it to phenotype. For example, if you have microhemorrhages you don't want to be taking Viagra or vasodilators but rather coat the glycocalyx if you have coagulation you do want anti-coagulants, if there's evidence of giant capillaries-then autoimmune

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH If there were more people like you, this and many other diseases wouldn’t be a burden anymore. Thank you Dr. Tal.

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Fascinating that we still can’t view a cell after centuries of manifestation in movements. We know so little

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH Incredible work. Are you planning to analyse immune cell flow behaviour as well using computer vision?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH watching them squeeze through single file is oddly moving. do they slow down at the bends or is that just the camera?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH very cool

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH how... how do you make these visible? dye?

@amyrochlin @CODA_research @tylerdmyers @PaigeSHansen @MIT_TRG @mhornig @technopolymath @TomerTalVH 🧐