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Might something different be going on for these people than other people who have high LDL cholesterol? Lean mass hyper-responders (LMHR) are defined as having a lean physique, high LDL, high HDL and low triglycerides while on a #Keto diet. Many LMHRs still choose to follow a ketogenic diet... to treat conditions like diabetes, insulin resistance, IBS, epilepsy, or mental disorders, and see great benefits to their health. PhD and Harvard Medical School student, Nick Norwitz MD PhD, himself a LMHR, sought an answer. In an N=1 experiment, Nick found that he could lower his LDL cholesterol twice as much with Oreo cookies compared to statins! High #LDL has traditionally been considered a risk factor for heart disease, but do we need to change how we think about LDL for a LMHR? If Oreos can beat statins, should that make us wonder if lowering LDL is the right approach for everyone? Watch the full YouTube interview here: Read the published study:show more

Metabolic Mind

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25,200 просмотров • 2 лет назад •via X (Twitter)

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Cardiology Has an LDL Obsession. What to Measure Instead... 🔗New video: 👇1 min clip on LDL vs Insulin Resistance The landscape of atherosclerosis is changing. New drugs are lowering LDL, total cholesterol and ApoB lower and lower, while larger risk factors like insulin resistance, obesity, and diabetes persist. If you want a comparison, lipoprotein insulin resistance score (LP-IR). Because 1.0 is risk neutral, insulin resistance score is a more than 14X more powerful predictor of new coronary heart disease than LDL. But we know who gets all the attention. Answer: [See Clip] That’s not proportional medicine Do you agree? For more nuances see the video linked above. cc Benjamin Bikman Dave Feldman

Cardiology Has an LDL Obsession. What to Measure Instead... 🔗New video: 👇1 min clip on LDL vs Insulin Resistance The landscape of atherosclerosis is changing. New drugs are lowering LDL, total cholesterol and ApoB lower and lower, while larger risk factors like insulin resistance, obesity, and diabetes persist. If you want a comparison, lipoprotein insulin resistance score (LP-IR). Because 1.0 is risk neutral, insulin resistance score is a more than 14X more powerful predictor of new coronary heart disease than LDL. But we know who gets all the attention. Answer: [See Clip] That’s not proportional medicine Do you agree? For more nuances see the video linked above. cc Benjamin Bikman Dave Feldman

Nick Norwitz MD PhD

77,831 просмотров • 6 месяцев назад

2/2) Here is the paper: Video Abstract: 🧠 Unique Population, Unique Data The LMHR group is distinct population with exceptionally high LDL-C, high HDL-C and low triglycerides that emerges as a metabolic response to carbohydrate restriction vis-a-vis the Lipid Energy Model ⚠️ Caveats These are preliminary data, so let’s not overstate the findings. However, dismissing them outright would ignore the unique metabolic response of this population, which differs significantly from other causes of high LDL-C. 📢 Your Role Now it’s time to put YOU to work! Share this paper, tweet, and video abstract widely. These data need to be discussed, even if (especially if) it makes some people uncomfortable. 🤓Further Learning I encourage you to explore more on ApoB, ACM, and different causes of high LDL. You can start on this 30+ video playlist on the topic. 🌍 Stay Open-Minded Avoid becoming a hyper-extremist—whether an “LDL denier” or “LMHR denier.” This research is still evolving, and we’ll make the most progress by staying open to new data and discussing it thoughtfully #LMHR #KetoDiet #LDL

2/2) Here is the paper: Video Abstract: 🧠 Unique Population, Unique Data The LMHR group is distinct population with exceptionally high LDL-C, high HDL-C and low triglycerides that emerges as a metabolic response to carbohydrate restriction vis-a-vis the Lipid Energy Model ⚠️ Caveats These are preliminary data, so let’s not overstate the findings. However, dismissing them outright would ignore the unique metabolic response of this population, which differs significantly from other causes of high LDL-C. 📢 Your Role Now it’s time to put YOU to work! Share this paper, tweet, and video abstract widely. These data need to be discussed, even if (especially if) it makes some people uncomfortable. 🤓Further Learning I encourage you to explore more on ApoB, ACM, and different causes of high LDL. You can start on this 30+ video playlist on the topic. 🌍 Stay Open-Minded Avoid becoming a hyper-extremist—whether an “LDL denier” or “LMHR denier.” This research is still evolving, and we’ll make the most progress by staying open to new data and discussing it thoughtfully #LMHR #KetoDiet #LDL

Nick Norwitz MD PhD

13,165 просмотров • 2 лет назад

"The Standard Of Care In Prescribing Statins Is Killing People." Gary Brecka "Cholesterol Does Not Cause Atherosclerotic Plaque Or Narrowing Of The Arteries." "There's No Correlation Between Elevated LDL & Cardiovascular Disease." "People Living To 100 Have High Cholesterol." Atherosclerosis is an inflammatory disease, not a cholesterol disease & never a statin deficiency. LDL is a transport molecule delivering cholesterol to repair the cell membrane of the arterial wall that has been damaged by lifestyle & environmental factors. LDL is preventive of disease & immune system protective. LDL Low Density Lipoprotein is responsible for these key functions: 🛞 LDL delivers fat-soluble vitamins A, D, E & K for critical functions. 🛞 LDL maintains cell membrane structure & keeps electron flow stable. 🛞 It transports antioxidants like vitamin E to fight oxidative stress. 🛞 It provides the raw material for making all steroid hormones. 🛞 It delivers energy-rich triglycerides to keep metabolism flexible. 🛞 LDL neutralizes bacterial toxins & supports innate immunity. 🛞 It builds lipid rafts that organize cell signaling & redox balance. 🛞 It helps structure water around membranes to maintain charge. 🛞 LDL supplies cholesterol to repair damaged tissues & membranes. The root causes of atherosclerosis, hardening of the arteries, calcification & plaque is not cholesterol...but a combination of these factors: Industrial Seed Oils Processed Sugar Excess Carbohydrates Insulin Resistance Ultra Processed Foods Smoking Obesity Environmental Toxins Poor Sleep Excess Calcium From Supplements Low Vitamin D Levels Magnesium Deficiency K2 Deficiency Lack of Exercise Stress Heavy Metals Most chronic disease happens within us, not to us, almost all atherosclerosis causal factors are modifiable by lifestyle changes. A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils & sugar, provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best biomarkers for heart health. Optimal TG/HDL ratio is 1.5 or less. 👇The Higher Your LDL, The Longer You Live👇 👇LDL Paradox: Higher LDL, Greater Longevity👇 👇LDL Does Not Cause Cardiovascular Disease👇 Speakers: Gary Brecka & Patrick Bet-David Podcast: PBD Podcast

Valerie Anne Smith

447,412 просмотров • 11 месяцев назад

LDL Cholesterol Saves Lives! What a fantastic example of cherry picking! Yes this person is right, in ELDERLY people, all cause mortality is greater amongst those with low LDL cholesterol… but WHY? And why didn’t he bring up all cause mortality with LDL levels amongst those who are not elderly? Oh because he doesn’t like that data. This is a textbook example of reverse causality. LDL Cholesterol is not protecting people from disease, but rather people with wasting diseases like cancer are more likely to be resistant to wasting if LDL is not low, indicating that they are not emaciated. But if we zoom out of the elderly and look at lifelong LDL exposure & the risk of mortality, it tells a very different story. Lifelong LDL cholesterol exposure has a LINEAR association with increased mortality, especially from cardiovascular disease (CVD) (PMIDs: 23083789, 38241044, & 30694319). In fact, reduced LDL exposure early in life throughout adulthood can reduce the chance of mortality from CVD by up to 3 times! Gee I wonder why he didn’t mention that. Additionally, the unremarkable results from many statin trials comes from the fact that often these are prescribed after a CVD event or later in life when someone has already done significant damage to their blood vessels. But even with that being the case we do see a clinically significant benefit in lowering the risk of mortality with statin use (PMIDs: 36233511 & 37368941). That said, statins can have some side effects & are not appropriate for everyone & you should speak to a cardiologist about your options if you have high LDL But this is a textbook example of carnivore zealots trying to do f***ery with science & giving you a 3rd of the info to try to trick you into believing their nonsense

LDL Cholesterol Saves Lives! What a fantastic example of cherry picking! Yes this person is right, in ELDERLY people, all cause mortality is greater amongst those with low LDL cholesterol… but WHY? And why didn’t he bring up all cause mortality with LDL levels amongst those who are not elderly? Oh because he doesn’t like that data. This is a textbook example of reverse causality. LDL Cholesterol is not protecting people from disease, but rather people with wasting diseases like cancer are more likely to be resistant to wasting if LDL is not low, indicating that they are not emaciated. But if we zoom out of the elderly and look at lifelong LDL exposure & the risk of mortality, it tells a very different story. Lifelong LDL cholesterol exposure has a LINEAR association with increased mortality, especially from cardiovascular disease (CVD) (PMIDs: 23083789, 38241044, & 30694319). In fact, reduced LDL exposure early in life throughout adulthood can reduce the chance of mortality from CVD by up to 3 times! Gee I wonder why he didn’t mention that. Additionally, the unremarkable results from many statin trials comes from the fact that often these are prescribed after a CVD event or later in life when someone has already done significant damage to their blood vessels. But even with that being the case we do see a clinically significant benefit in lowering the risk of mortality with statin use (PMIDs: 36233511 & 37368941). That said, statins can have some side effects & are not appropriate for everyone & you should speak to a cardiologist about your options if you have high LDL But this is a textbook example of carnivore zealots trying to do f***ery with science & giving you a 3rd of the info to try to trick you into believing their nonsense

Layne Norton, PhD

89,928 просмотров • 1 год назад

Megyn Kelly’s doctor told her statins should be in the drinking water. Her hormones doctor said absolutely not. So she asked Dr. Paul Saladino for the truth. His take: Cholesterol is essential for brain and hormone health. The real issue isn’t your LDL number in isolation, it’s your overall metabolic health. Even “normal” cholesterol can hide risk if fasting insulin, thyroid, or A1C is off. A 2025 study from The Lundquist Institute (KETO-CTA trial) found that in metabolically healthy people, high LDL cholesterol showed no significant increase in plaque buildup or cardiovascular risk. Metabolic health appears to matter far more than LDL levels alone. What’s your take, are we over-fearing cholesterol and under-focusing on real metabolic health?

Megyn Kelly’s doctor told her statins should be in the drinking water. Her hormones doctor said absolutely not. So she asked Dr. Paul Saladino for the truth. His take: Cholesterol is essential for brain and hormone health. The real issue isn’t your LDL number in isolation, it’s your overall metabolic health. Even “normal” cholesterol can hide risk if fasting insulin, thyroid, or A1C is off. A 2025 study from The Lundquist Institute (KETO-CTA trial) found that in metabolically healthy people, high LDL cholesterol showed no significant increase in plaque buildup or cardiovascular risk. Metabolic health appears to matter far more than LDL levels alone. What’s your take, are we over-fearing cholesterol and under-focusing on real metabolic health?

Camus

316,726 просмотров • 2 месяцев назад

"As A Cardiologist, I Don't Take Statin Drugs & Here's Why..." Dr Jack Wolfson, MD "I like My Testosterone & Libido...Statins Harm Hormone Production. I Like My Brain & Want To Be Able To Use It...Statins Lead To Dementia. I Like NOT Having Diabetes...Statins Cause Diabetes." Cholesterol Is A Nutrient, Not An Enemy... There are no benefits to taking a Statin, yes they lower your cholesterol, but they do not lower Cardiovascular Risk or Disease. Synthetically lowering cholesterol levels is very harmful to every bodily system. 🔴Statins cause CoQ10 deficiency, resulting in muscle pain & Mitochondrial Dysfunction. 🔴Statins cause liver & pancreas damage, leading to insulin resistance & type 2 diabetes. 🔴Every Statin crosses the blood brain barrier & shuts off the enzyme of cholesterol production which then leads to Alzheimer's. 🔴Statins inhibit Heme A, a vital component of the electron transport chain for energy. 🔴Statins stop Dolichol, a crucial molecule in protein glycosylation in the brain, deficiency leads to Parkinson's & other brain disorders. LDL Is Not The Enemy Either... LDL is a transport molecule delivering cholesterol to repair the cell membrane of the arterial wall that has been damaged by lifestyle & environmental factors. LDL is preventive of disease & immune system protective. 🛞 It helps structure water around membranes to maintain charge. 🛞 LDL maintains cell membrane structure & keeps electron flow stable. 🛞 LDL delivers fat-soluble vitamins A, D, E & K for critical functions. 🛞 It transports antioxidants like vitamin E to fight oxidative stress. 🛞 It provides the raw material for making all steroid hormones. 🛞 LDL neutralizes bacterial toxins & supports innate immunity. 🛞 It delivers energy-rich triglycerides to keep metabolism flexible. 🛞 It builds lipid rafts that organize cell signaling & redox balance. 🛞 LDL supplies cholesterol to repair damaged tissues & membranes. Cholesterol Lowering Medications Will Cause These Chronic Health Dysfunctions: Dementia & Alzheimer's Disease Cancer Pancreatitis Liver Inflammation & Damage Diabetes Chronic Depression Parkinson's Disease ALS (Lou Gehrig's Disease) Hormonal Deficiency Brain Damage Multiple Sclerosis Muscle Pain & Tearing Fatigue & Weakness Neuropathy Heart Failure Vertigo Cognitive Impairment A diet prioritizing whole foods & nutrient dense animal foods provides the best healthy cholesterol profile which provides all the building blocks for proper function of the human body for life. Heart health is achieved thru eliminating harmful seed oils, excess sugar, processed foods, excess grains & starchy carbs. Eliminating these will keep Triglycerides low & HDL high, which is one of the best biomarkers for heart health. For optimal TG/HDL ratio, the number to aim for is less than 1.5 when dividing triglyceride level by HDL level. 👇LDL Paradox: Higher LDL, Greater Longevity👇 👇LDL Does Not Cause Cardiovascular Disease👇 👇The Higher Your LDL, The Longer You Live👇 Speaker: Dr Jack Wolfson, MD Cardiologist

Valerie Anne Smith

341,943 просмотров • 9 месяцев назад

Joe Rogan’s guest Gary Brecka dismantled one of the most profitable narratives in modern medicine — the “good vs bad cholesterol” myth. For decades, pharma-backed health campaigns have pushed the idea that LDL is the bad cholesterol and HDL the good, persuading millions to take statins to lower LDL at all costs. But according to Brecka and cardiologists like Dr. Aseem Malhotra, this simplistic model ignores the real biology. What actually matters, Brecka explains, is particle size. When triglycerides rise — often due to high-sugar, high-glycaemic diets and insulin resistance — LDL particles shrink. Smaller particles (the “BBs”) can penetrate arterial walls, become oxidized, and trigger inflammation. Large, buoyant LDL particles (the “basketballs”) do not. Two people can have the same total cholesterol, but vastly different cardiovascular outcomes — depending on triglyceride levels, insulin sensitivity, and inflammation markers like C-reactive protein. Brecka emphasizes that cholesterol isn’t the villain; it’s the firefighter showing up to the fire — a response to inflammation, not the cause of it. Cardiovascular health, he argues, should focus on the metabolic picture: – Fasting insulin – Blood glucose and A1C – Triglyceride-to-HDL ratio – C-reactive protein Not simply on driving LDL numbers down with lifelong statin use. Brecka even noted that in his work processing death claims for centenarians, he never came across one who didn’t have elevated LDL levels — raising serious questions about whether low cholesterol truly equals longevity. This challenges decades of medical orthodoxy and billions in drug sales. But the evidence is catching up: metabolic dysfunction, not LDL itself, is the real culprit behind atherosclerosis.

Joe Rogan’s guest Gary Brecka dismantled one of the most profitable narratives in modern medicine — the “good vs bad cholesterol” myth. For decades, pharma-backed health campaigns have pushed the idea that LDL is the bad cholesterol and HDL the good, persuading millions to take statins to lower LDL at all costs. But according to Brecka and cardiologists like Dr. Aseem Malhotra, this simplistic model ignores the real biology. What actually matters, Brecka explains, is particle size. When triglycerides rise — often due to high-sugar, high-glycaemic diets and insulin resistance — LDL particles shrink. Smaller particles (the “BBs”) can penetrate arterial walls, become oxidized, and trigger inflammation. Large, buoyant LDL particles (the “basketballs”) do not. Two people can have the same total cholesterol, but vastly different cardiovascular outcomes — depending on triglyceride levels, insulin sensitivity, and inflammation markers like C-reactive protein. Brecka emphasizes that cholesterol isn’t the villain; it’s the firefighter showing up to the fire — a response to inflammation, not the cause of it. Cardiovascular health, he argues, should focus on the metabolic picture: – Fasting insulin – Blood glucose and A1C – Triglyceride-to-HDL ratio – C-reactive protein Not simply on driving LDL numbers down with lifelong statin use. Brecka even noted that in his work processing death claims for centenarians, he never came across one who didn’t have elevated LDL levels — raising serious questions about whether low cholesterol truly equals longevity. This challenges decades of medical orthodoxy and billions in drug sales. But the evidence is catching up: metabolic dysfunction, not LDL itself, is the real culprit behind atherosclerosis.

Camus

210,451 просмотров • 9 месяцев назад

🚨It’s back… The Oreo vs Statin Experiment… 1/4) To catch you up, while a student at Harvard Medical School I conducted an experiment where I my LDL cholesterol TWICE as much with Oreo cookies as compared to high-dose statins, a viral experiment that was published in peer-review. The “Oreo protocol” dropped my LDL > 70%, completely crushing the statin. It was dramatic by design — a metabolic stunt (albeit legitimate science) meant to grab headlines. And it did! Now, for the first time I am revisiting that experiment. Not just what it proved… What we’ve learned… And what’s next. This wasn’t just a cholesterol hack — it was a social experiment. And you’re the data points. Drop your questions, comments, and what you want to see next. ht/ Dave Feldman Adrian Soto-Mota

🚨It’s back… The Oreo vs Statin Experiment… 1/4) To catch you up, while a student at Harvard Medical School I conducted an experiment where I my LDL cholesterol TWICE as much with Oreo cookies as compared to high-dose statins, a viral experiment that was published in peer-review. The “Oreo protocol” dropped my LDL > 70%, completely crushing the statin. It was dramatic by design — a metabolic stunt (albeit legitimate science) meant to grab headlines. And it did! Now, for the first time I am revisiting that experiment. Not just what it proved… What we’ve learned… And what’s next. This wasn’t just a cholesterol hack — it was a social experiment. And you’re the data points. Drop your questions, comments, and what you want to see next. ht/ Dave Feldman Adrian Soto-Mota

Nick Norwitz MD PhD

54,291 просмотров • 8 месяцев назад

You know I like to ask provocative questions 🧐… Could a NEW 💊 DRUG for Fatty Liver impact LDL cholesterol in lean metabolically healthy people on a #keto diet? If so… HOW and what could we learn!? 👉 New exciting data in NEJM on a phase III trial for a thyroid receptor beta liver-targeting drug shows impressive results for reversing fatty liver In association, there are decreases in LDL-C, along with ApoB, ApoCIII, and even Lp(a) But what happens were we to put this same drug in a VERY different metabolic context? 🔨Would said drug hammer LDL-C in #LMHR into the floor simply because their LDL levels have so far to drop? OR could the opposite happen? ⚡️Could ramping up liver metabolism increase, rather than decrease, LDL-C in LMHR. I don’t know! But point being: CONTEXT, CONTEXT, CONTEXT. Just like OREO Cookie lowered LDL-C in #LMHR, when you change the metabolic context, sometimes you get surprising results And, it’s fair game to speculate (EMPHASIS: I AM SPECULATING) and pose bold ideas, provided we are CLEAR we can’t truly know the answers until we test. For more, see video: I, for one, think the NEJM data are promising for the indicated use case, and humbly share where my scientific mind ‘wanders’ when presented with these data, framed by my own field and interests NEJM paper: P.S. I know people are going to go "off" suggesting I'm recommending X, Y or Z or saying something about "dangers" of high LDL in #LMHR. I'm not. I'm just open-mindedly and transparently providing a provocative thought puzzle... if your emotions are stimulated, I did my job I suppose... if you let them get the better of you... that's on you 😜 cc Dave Feldman Adrian Soto-Mota (my #LEM bros!) William Cromwell, MD LipoFan Simon Hill MSc, BSc Matthew A. Nehs Dominic D'Agostino STEM-Talk

You know I like to ask provocative questions 🧐… Could a NEW 💊 DRUG for Fatty Liver impact LDL cholesterol in lean metabolically healthy people on a #keto diet? If so… HOW and what could we learn!? 👉 New exciting data in NEJM on a phase III trial for a thyroid receptor beta liver-targeting drug shows impressive results for reversing fatty liver In association, there are decreases in LDL-C, along with ApoB, ApoCIII, and even Lp(a) But what happens were we to put this same drug in a VERY different metabolic context? 🔨Would said drug hammer LDL-C in #LMHR into the floor simply because their LDL levels have so far to drop? OR could the opposite happen? ⚡️Could ramping up liver metabolism increase, rather than decrease, LDL-C in LMHR. I don’t know! But point being: CONTEXT, CONTEXT, CONTEXT. Just like OREO Cookie lowered LDL-C in #LMHR, when you change the metabolic context, sometimes you get surprising results And, it’s fair game to speculate (EMPHASIS: I AM SPECULATING) and pose bold ideas, provided we are CLEAR we can’t truly know the answers until we test. For more, see video: I, for one, think the NEJM data are promising for the indicated use case, and humbly share where my scientific mind ‘wanders’ when presented with these data, framed by my own field and interests NEJM paper: P.S. I know people are going to go "off" suggesting I'm recommending X, Y or Z or saying something about "dangers" of high LDL in #LMHR. I'm not. I'm just open-mindedly and transparently providing a provocative thought puzzle... if your emotions are stimulated, I did my job I suppose... if you let them get the better of you... that's on you 😜 cc Dave Feldman Adrian Soto-Mota (my #LEM bros!) William Cromwell, MD LipoFan Simon Hill MSc, BSc Matthew A. Nehs Dominic D'Agostino STEM-Talk

Nick Norwitz MD PhD

29,261 просмотров • 2 лет назад

There’s been a lot of buzz—and confusion—about the new Keto-CTA study, examining plaque progression in Lean Mass Hyper-Responders (LMHRs). Much of the social media debate has centered on whether high LDL on keto is safe or dangerous, driven largely by how to interpret the supplemental table comparing this study to others on LDL and plaque progression. In this episode of the Metabolic Mind Podcast, we sit down with Dr. Matthew Budoff, a world-renowned cardiologist, cardiac CT researcher, and the study's lead investigator, to discuss the the supplemental table, what the plaque markers mean, and how this fits into the discussion of high- vs -low-risk plaque progression. In this episode, we cover: ✅ What PAV (Percent Atheroma Volume) is, what it actually measures, and why it matters ✅ Why a 50% increase in plaque may sound scary, but can be deceiving ✅ The difference between “treatment-naive” and “treated” participants ✅ What the Miami Heart Study comparison reveals about keto, LDL, and plaque ✅ Why LDL alone may not tell the whole story about heart disease risk ✅ How some high-risk individuals may still benefit from statins and other therapies This study doesn’t answer whether keto causes heart disease or not. Instead, it shows that high LDL on a ketogenic diet is not a reliable predictor of plaque progression across all individuals. What is predictive? The presence of existing plaque. 💡 Key takeaway: Relying on surrogate markers of heart disease, like LDL and ApoB, is not the best way to assess heart disease risk in all populations. If you're concerned about how elevated LDL may be affecting your heart health, the best next step is to speak with your doctor about cardiac imaging to directly assess plaque and gain a clearer picture of your individual risk. Expert Featured: - Dr. Matthew Budoff - X: - Resources Mentioned: Plaque Begets Plaque, ApoB Does Not CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope Brain Energy: The Metabolic Theory of Mental Illness Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at

There’s been a lot of buzz—and confusion—about the new Keto-CTA study, examining plaque progression in Lean Mass Hyper-Responders (LMHRs). Much of the social media debate has centered on whether high LDL on keto is safe or dangerous, driven largely by how to interpret the supplemental table comparing this study to others on LDL and plaque progression. In this episode of the Metabolic Mind Podcast, we sit down with Dr. Matthew Budoff, a world-renowned cardiologist, cardiac CT researcher, and the study's lead investigator, to discuss the the supplemental table, what the plaque markers mean, and how this fits into the discussion of high- vs -low-risk plaque progression. In this episode, we cover: ✅ What PAV (Percent Atheroma Volume) is, what it actually measures, and why it matters ✅ Why a 50% increase in plaque may sound scary, but can be deceiving ✅ The difference between “treatment-naive” and “treated” participants ✅ What the Miami Heart Study comparison reveals about keto, LDL, and plaque ✅ Why LDL alone may not tell the whole story about heart disease risk ✅ How some high-risk individuals may still benefit from statins and other therapies This study doesn’t answer whether keto causes heart disease or not. Instead, it shows that high LDL on a ketogenic diet is not a reliable predictor of plaque progression across all individuals. What is predictive? The presence of existing plaque. 💡 Key takeaway: Relying on surrogate markers of heart disease, like LDL and ApoB, is not the best way to assess heart disease risk in all populations. If you're concerned about how elevated LDL may be affecting your heart health, the best next step is to speak with your doctor about cardiac imaging to directly assess plaque and gain a clearer picture of your individual risk. Expert Featured: - Dr. Matthew Budoff - X: - Resources Mentioned: Plaque Begets Plaque, ApoB Does Not CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope Brain Energy: The Metabolic Theory of Mental Illness Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at

Metabolic Mind

98,147 просмотров • 1 год назад

"If Your Cholesterol Is Below 200, You Have A Problem..." Dr Kevin Reese, PhD Lowering Cholesterol Is Harmful & Dangerous-- Resulting In Chronic Disease, Dementia, Stroke, Cancer & Early Death. 8 Reasons Why You Should NEVER Take A Cholesterol Lowering Statin. 1: Statins cause Brain Damage. Neuroinflammation & Mitochondrial dysfunction resulting in rapid cognitive decline & early onset Alzheimer's. 2: Statins stop Dolichol, a crucial molecule in protein glycosylation in the brain, deficiency leads to Alzheimer's, Lewy Body Dementia, Parkinson's & other brain disorders. 3: Statins cause CoQ10 deficiency, resulting in muscle pain & Mitochondrial Dysfunction, leading to heart attack & stroke. 4: Statins induce Type 2 Diabetes at the rate of 71%. By lowering cholesterol in the blood, Statins interfere with the body's ability to use insulin, thereby causing insulin resistance & high blood sugar levels. 5: Statins inhibit Heme A, a vital component of the electron transport chain for energy. Crucial for oxygen storage & respiratory function. 6: Statins cause Muscle Damage. Breakdown of muscle tissue & profuse tearing resulting in Rhabdomyolysis. 7: Statins cause Liver Damage. Drug Induced Liver Injury (DILI) with jaundice, acute & chronic liver failure & abdominal pain. 8: Statins increase the risk of brain bleeds. Hemorrhagic Stroke risk increases 3X when cholesterol lowering statins cause LDL to go below 70 mg/dL. Chronic Conditions Caused By Cholesterol Lowering Statins: Muscle Pain Muscle Tearing Weakness Neuropathy Heart Failure Dizziness/Vertigo Cognitive Impairment Dementia Alzheimer's Disease Cancer Pancreatitis Liver Damage Diabetes Depression Parkinson's Disease ALS (Lou Gehrig's Disease) Testosterone Deficiency Erectile Dysfunction Estrogen Deficiency Vaginal Atrophy Brain Damage Multiple Sclerosis There Is No Cardiovascular Benefit From Taking A Cholesterol Lowering Statin Because Cholesterol Does Not Cause Atherosclerosis Plaque, Arterial Stiffness, Heart Attack Or Stroke. Inflammation & Damage To The Arterial Wall Is The Cause Of Cardiovascular Disease, Not Cholesterol. Cholesterol Is There To Heal The Damage Done By Other Lifestyle Factors Such As High Carb/High Sugar/High Seed Oil Diet, Ultra Processed Foods, Smoking, Stress, Etc. The Research Is Clear. The Higher Your LDL, The Longer You Live. A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils, sugar & processed foods provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best Biomarkers for Cardiac health. TG/HDL ratio optimally should be less than 2.0 & even better at 1.5 or less. 👇The Higher Your LDL, The Longer You Live👇 👇Low Cholesterol Causes Heart Disease & Cancer👇 👇Low LDL Causes Hemorrhagic Stroke👇 Speaker: Dr Kevin Reese, PhD

Valerie Anne Smith

234,391 просмотров • 1 год назад

Chemically Lowering Cholesterol With A Statin Does Not Add Years To Your Life...It Takes Years From Your Life. 22% Increase In Heart Disease Deaths. 3X Increase In Hemorrhagic Stroke Brain Bleeds. 36% Increase In New Onset Type 2 Diabetes. Causes Dementia, ALS & Parkinson's. Research has confirmed over & over that the higher your LDL the longer you live. LDL is a transport molecule for cholesterol & a vital immune system regulator. Lowering LDL thru statin drugs has deadly & deleterious effects. It has been documented that when LDL drops below 70 mg/dL, hemorrhagic strokes (brain bleeds) increase almost 3 fold. When total cholesterol is chemically lowered below 180 mg/dL the rate of cancer & dementia increases drastically. And when total cholesterol stays below 150, chronic recurring cancer & autoimmune diseases strike. 36% of those on statin therapy will be diagnosed with new onset type 2 diabetes. Saturated Fats & Cholesterol Have No Effect on CVD Outcomes, Including Heart Attacks, Strokes, CVD Mortality & Total Mortality. There are no benefits to taking a Statin, yes they lower your cholesterol, but they do not lower Cardiovascular Risk or Disease. Statins are dangerous because low cholesterol causes deadly side effects: 💊Statins cause CoQ10 & Heme A deficiency, resulting in muscle pain & Mitochondrial Dysfunction. 💊Statins stop Dolichol, a crucial molecule in protein glycosylation in the brain, deficiency leads to Parkinson's & other brain disorders. 💊Statins cause liver & pancreas damage, leading to insulin resistance & type 2 diabetes. 💊Every Statin crosses the blood brain barrier & shuts off the enzyme of cholesterol production leading to Dementia & Alzheimer's. 💊Cholesterol should not be lowered, it's critical for Vitamin D & all hormones, digestion, every cell should be saturated with healthy cholesterol. Chronic Conditions Caused By Cholesterol Lowering Statins: Muscle Pain & Tearing Weakness Neuropathy Heart Failure Dizziness/Vertigo Cognitive Impairment Dementia Alzheimer's Disease Cancer Pancreatitis Liver Damage Diabetes Depression Parkinson's Disease ALS (Lou Gehrig's Disease) Hormonal Deficiency Brain Damage Multiple Sclerosis A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils, sugar & processed foods provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best Biomarkers for Cardiac health. TG/HDL ratio optimally should be less 1.5 or less. 👇22% Increase In Heart Disease Deaths👇 👇Low LDL Causes 3X Hemorrhagic Strokes👇 👇The Higher Your LDL, The Longer You Live👇 👇36% Increase New Onset Type 2 Diabetes👇 Video: @extremehealthradio2

Valerie Anne Smith

33,741 просмотров • 1 год назад

"The Higher Your LDL, The Longer You're Going To Live." Dr Aseem Malhotra, Cardiologist "The Greater The Financial Interest In A Given Field, The Less Likely The Research Findings Are to be True." "The Most Lucrative Drug In The History Of Medicine Are Statins." $19 Billion Dollar Profit Industry Totalling 818 Million Prescriptions Annually. "The Benefit Of Statins For Both Low Risk & High Risk Primary Prevention Is ONLY 1%...1 In 100." "There Is No Correlation Between Elevated LDL Level & Events Of Cardiovascular Disease. In Fact, It's The Inverse. There Is A Correlation Between Higher LDL Level & Longevity." "The Higher The LDL, The Longer You're Going To Live, Because It Has A Vital Role In Your Immune System." "Just Because Cholesterol Is At The Scene Of the Crime, Doesn't Mean It's The Perpetrator." LDL serves an important & vital purpose for vibrant health. LDL contains the antioxidants Vitamin E, CoQ10 & Carotenoids that kill off free radicals. This reduces inflammation & oxidative damage, which are the true causes of cardiovascular disease. LDL is a transport molecule delivering cholesterol to repair the cell membrane of the arterial wall. LDL is preventive of disease & immune system protective. Cholesterol is trying to clear the inflammation & put out the fire caused by other lifestyle issues in order to get the body to return to Homeostasis. Atherosclerosis Is An Inflammatory Disease, Not A Cholesterol Disease or A Statin Deficiency. A Fireman shows up to put out a fire. He's not the cause of the fire. Cholesterol shows up to put out the fire of Inflammation in the Arterial Wall. Cholesterol is not the cause of the Inflammation that turns to Plaque. Eliminate The Root of The Inflammation Which Causes The Damage & Atherosclerosis: Industrial Seed Oils Processed Sugar Carbohydrates Insulin Resistance Ultra Processed Foods Smoking Obesity Environmental Toxins Poor Sleep Low Vitamin D Levels Magnesium Deficiency K2 Deficiency Lack of Exercise Stress These Are All Modifiable Risk Factors. Most Chronic Disease Happens Within Us, It Does Not Happen To Us. A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils & sugar, provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best biomarkers for heart health. TG/HDL ratio optimally should be less than 2.0 & even better at 1.5 or less. 👇The Higher Your LDL, The Longer You Live👇 👇LDL Paradox: Higher LDL, Greater Longevity👇 👇LDL Does Not Cause Cardiovascular Disease👇 Speakers: Dr Aseem Malhotra & Gary Brecka Video: The Ultimate Human Podcast

Valerie Anne Smith

238,554 просмотров • 1 год назад

Why do some people with crazy high LDL-C and ApoB develop no plaque in their arteries, while others – including those with far lower LDL and lower ApoB – do develop plaque? 🫀- featuring Thomas Dayspring So, let’s tackle one possible explanation centered around the following term: “Transcytosis.” ✋Quick Definition & Analogy Transcytosis is the process whereby a cell – in this case, the endothelial cells lining your arteries – sucks up something from outside (here, an LDL particle containing cholesterol), passes that something through its interior, and then out the other side. By way of analogy, think of your artery wall like an exclusive nightclub. Some particles get waved in VIP-style. Others get stuck outside. But what if LDL wasn’t just passively slipping through a hole in the wall, but was actually being escorted through by a bouncer? That is - more or less - transcytosis. #LDL #ApoB #heartdisease #cholesterol #LEM #LMHR #HDL #hearthealth #insulinresistance #metabolichealth #cholesterolcode #staycurious Dave Feldman Adrian Soto-Mota LipoFan Austin Dudzinski, PharmD, BCACP

Why do some people with crazy high LDL-C and ApoB develop no plaque in their arteries, while others – including those with far lower LDL and lower ApoB – do develop plaque? 🫀- featuring Thomas Dayspring So, let’s tackle one possible explanation centered around the following term: “Transcytosis.” ✋Quick Definition & Analogy Transcytosis is the process whereby a cell – in this case, the endothelial cells lining your arteries – sucks up something from outside (here, an LDL particle containing cholesterol), passes that something through its interior, and then out the other side. By way of analogy, think of your artery wall like an exclusive nightclub. Some particles get waved in VIP-style. Others get stuck outside. But what if LDL wasn’t just passively slipping through a hole in the wall, but was actually being escorted through by a bouncer? That is - more or less - transcytosis. #LDL #ApoB #heartdisease #cholesterol #LEM #LMHR #HDL #hearthealth #insulinresistance #metabolichealth #cholesterolcode #staycurious Dave Feldman Adrian Soto-Mota LipoFan Austin Dudzinski, PharmD, BCACP

Nick Norwitz MD PhD

17,699 просмотров • 1 год назад

Nick Norwitz Reveals Why High Cholesterol Doesn't Cause Heart Disease In this episode of Stay Off My Operating Table, Nick Norwitz MD PhD breaks down why the medical world has been treating cholesterol as the disease itself and why that's dead wrong. One extraordinary case of a patient with sky-high LDL and zero arterial plaque is challenging the entire conventional model of heart disease. If you think managing your cholesterol numbers means you're managing your heart health, this conversation will change the way you think. Watch the full episode here 👉 #CholesterolMyths #HeartHealth #LDLCholesterol #CardiovascularHealth #FunctionalMedicine

Nick Norwitz Reveals Why High Cholesterol Doesn't Cause Heart Disease In this episode of Stay Off My Operating Table, Nick Norwitz MD PhD breaks down why the medical world has been treating cholesterol as the disease itself and why that's dead wrong. One extraordinary case of a patient with sky-high LDL and zero arterial plaque is challenging the entire conventional model of heart disease. If you think managing your cholesterol numbers means you're managing your heart health, this conversation will change the way you think. Watch the full episode here 👉 #CholesterolMyths #HeartHealth #LDLCholesterol #CardiovascularHealth #FunctionalMedicine

Heart Surgeon Dr. Philip Ovadia

79,954 просмотров • 3 месяцев назад

"The Longest Lived People Had High Cholesterol Levels...And Yet We Live In A World That Hates Cholesterol!" Dr Ben Bikman, PhD "Cholesterol Is A Molecule Of Life & Mitochondria. We Need LDL, It Actually Helps The Body Fight Infections." "LDL Is Also An Unsung Hero Of Immunity." "We Have Chosen Markers In Modern Medicine That We Have Well Designed Drugs, So It's A Really Really Good Way To Sell A Lot Of Drugs." Research has confirmed over & over that the higher your LDL the longer you live. LDL is a transport molecule for cholesterol & a vital immune system regulator. Lowering LDL thru statin drugs has deadly & deleterious effects. For example, It has been documented that when LDL drops below 70 mg/dL, hemorrhagic strokes (brain bleeds) increase almost 3 fold. When total cholesterol is chemically lowered below 180 mg/dL the rate of cancer & dementia increases drastically. And when total cholesterol stays below 150, chronic illnesses like cancer & autoimmune diseases occur & cannot be healed nor put into remission. Without Abundant Cholesterol Our Bodies Cannot Make: Testosterone Aldosterone Cortisol DHT Dihydrotestosterone DHEA Dehydroepiandrosterone Estradiol Estriol Estrone Progesterone Vitamin D LDL, HDL & Cholesterol Are Essential For Life: Protects against chemicals, toxins & heavy metals. Prevents dementia & cognitive decline. Protects against all cause mortality. Production of all steroid hormones. Bone density & Osteoporosis prevention. Protective against stroke & heart disease. Important for lungs & airways. Building block of all cells & mitochondria. Absorption of Vitamins A, D, E & K. Critical for digestion & bile acids. Immune system protection against infections. Protection against bacteria, pathogens & viruses. Lowers risk of cancer & death. Lowers risk of depression & suicide. Lowers stress, cortisol & anxiety. For Vibrant Metabolic & Mitochondrial Health: A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils, sugar & processed foods provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best Biomarkers for Cardiovascular health. TG/HDL ratio optimally should be 1.5 or less. 👇The Higher Your LDL, The Longer You Live👇 👇Low Cholesterol Causes Heart Disease & Cancer👇 👇Low LDL Causes 3X Hemorrhagic Strokes👇 Speaker: Benjamin Bikman Podcast: DiaryOfaCEO Video: CarnivoreJT

Valerie Anne Smith

239,365 просмотров • 1 год назад

"The Higher Your Cholesterol The Longer You Live" "If you have Low Cholesterol, be very afraid." Cardiologist Dr. Jack Wolfson / Natural Heart Doctor shares the latest research on the critical importance of Cholesterol for vibrant health. "The Higher the LDL Cholesterol, The Lower Your Risk of Dying." "The LDL Paradox: Higher LDL-Cholesterol is Associated with Greater Longevity" Lead Authors: Uffe Ravnskov & Dr Aseem Malhotra 👇👇👇Link to Study👇👇👇 "The worry over Total Cholesterol & Heart Attack risk is a fallacy from the 60s & 70s" "Cholesterol is critically important, that's why all animals have it, that why breast milk has it, that's why eggs contain it because that's how a chicken comes to life." "Do not fear total Cholesterol, in fact for people older than 60, the higher the total Cholesterol, the longer they live." "LDL has many important roles in the body. Cholesterol itself, Triglycerides, fat soluble Vitamins, CoQ10 heart protection & optimal immune function."

"The Higher Your Cholesterol The Longer You Live" "If you have Low Cholesterol, be very afraid." Cardiologist Dr. Jack Wolfson / Natural Heart Doctor shares the latest research on the critical importance of Cholesterol for vibrant health. "The Higher the LDL Cholesterol, The Lower Your Risk of Dying." "The LDL Paradox: Higher LDL-Cholesterol is Associated with Greater Longevity" Lead Authors: Uffe Ravnskov & Dr Aseem Malhotra 👇👇👇Link to Study👇👇👇 "The worry over Total Cholesterol & Heart Attack risk is a fallacy from the 60s & 70s" "Cholesterol is critically important, that's why all animals have it, that why breast milk has it, that's why eggs contain it because that's how a chicken comes to life." "Do not fear total Cholesterol, in fact for people older than 60, the higher the total Cholesterol, the longer they live." "LDL has many important roles in the body. Cholesterol itself, Triglycerides, fat soluble Vitamins, CoQ10 heart protection & optimal immune function."

Valerie Anne Smith

1,083,505 просмотров • 1 год назад

Normal Total Cholesterol level used to be 300. Then Normal Was Changed 190. Now They Want It Closer To 150. Big Pharma Keeps Moving The Goalpost... Barbara O'Neill If Someone's On A Fat Free Diet & A Cholesterol Lowering Medication...That's A Recipe For Brain Destruction. 8 Reasons Why You Should NEVER Take A Cholesterol Lowering Statin: 1: Statins cause Brain Damage. Neuroinflammation & Mitochondrial dysfunction resulting in rapid cognitive decline & early onset Alzheimer's. 2: Statins stop Dolichol, a crucial molecule in protein glycosylation in the brain, deficiency leads to Alzheimer's, Lewy Body Dementia, Parkinson's & other brain disorders. 3: Statins cause CoQ10 deficiency, resulting in muscle pain & Mitochondrial Dysfunction, leading to heart attack & stroke. 4: Statins induce Type 2 Diabetes at the rate of 71%. By lowering cholesterol in the blood, Statins interfere with the body's ability to use insulin, thereby causing insulin resistance & high blood sugar levels. 5: Statins inhibit Heme A, a vital component of the electron transport chain for energy. Crucial for oxygen storage & respiratory function. 6: Statins cause Muscle Damage. Breakdown of muscle tissue & profuse tearing resulting in Rhabdomyolysis. 7: Statins cause Liver Damage. Drug Induced Liver Injury (DILI) with jaundice, acute & chronic liver failure & abdominal pain. 8: Statins increase the risk of brain bleeds. Hemorrhagic Stroke risk increases 3X when cholesterol lowering statins cause LDL to go below 70 mg/dL. Chronic Conditions Caused By Cholesterol Lowering Statins: Muscle Pain Muscle Tearing Weakness Neuropathy Heart Failure Dizziness/Vertigo Cognitive Impairment Dementia Alzheimer's Disease Cancer Pancreatitis Liver Damage Diabetes Depression Parkinson's Disease ALS (Lou Gehrig's Disease) Testosterone Deficiency Erectile Dysfunction Estrogen Deficiency Vaginal Atrophy Brain Damage Multiple Sclerosis There Is No Cardiovascular Benefit From Taking A Cholesterol Lowering Statin Because Cholesterol Does Not Cause Atherosclerosis Plaque, Arterial Stiffness, Heart Attack Or Stroke. Inflammation & Damage To The Arterial Wall Is The Cause Of Cardiovascular Disease, Not Cholesterol. Cholesterol Is There To Heal The Damage Done By Other Lifestyle Factors Such As High Carb/High Sugar/High Seed Oil Diet, Ultra Processed Foods, Smoking, Stress, Etc. The Research Is Clear. The Higher Your LDL, The Longer You Live. A low carbohydrate diet prioritizing nutrient dense animal foods, eliminating harmful seed oils, sugar & processed foods provides the best healthy cholesterol profile. This approach keeps Triglycerides low & HDL high, which is one of the best Biomarkers for Cardiac health. TG/HDL ratio optimally should be 1.5 or less. 👇The Higher Your LDL, The Longer You Live👇 👇Low Cholesterol Is Deadly👇 👇High Cholesterol Prevents Atherosclerosis👇 Speaker: Barbara O'Neill Video: @health1solutions

Valerie Anne Smith

714,558 просмотров • 1 год назад