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Neuralink just solved a very serious brain-interface problem. Through-dura electrode implantation. The dura is basically the brain’s armor. Tough enough that surgeons normally cut through it with a scalpel. Neuralink inserted electrode threads straight through the dura and into the cortex while keeping the dura intact. Tiny threads. Very...

74,318 次观看 • 11 天前 •via X (Twitter)

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Elon Musk just made every skill you’ve ever earned sound like a waste of time. Musk: “Down the road with a Neuralink, you can just upload any subject instantly. You wanna fly a helicopter? No problem. Any given skill, you just upload it instantly.” Not faster learning. Not better education. Instant upload. The surgeon who spent 12 years learning to cut. The pilot who logged 5,000 hours learning to fly. The attorney who gave a decade to case law. Their entire advantage erased in a software update. We built civilization on one assumption. That knowledge is earned through suffering. That the distance between who you are and who you want to be is measured in discipline and years. Neuralink doesn’t close that distance. It deletes it. And what that kills isn’t employment. It’s identity. We don’t just use skills. We become them. Ask a surgeon who they are. They don’t say “I work in medicine.” They say surgeon. Ask a pilot. They say pilot. The identity was never the skill itself. It was the cost of acquiring it. If everyone can upload surgery in seconds, no one is a surgeon anymore. The skill still exists. The meaning behind it doesn’t. For centuries we told ourselves that mastery is what builds character. That the hardest thing you ever earned is the closest thing to purpose you’ll ever find. Neuralink doesn’t threaten your career. It threatens the story you tell yourself about why your life matters. The question nobody wants to sit with isn’t whether Musk can build this. It’s who you are when the thing that took you 20 years to become can be downloaded in 20 seconds.

Dustin

39,062 次观看 • 2 个月前

Neuralink Integration with ANKTIVA for Revolutionary Immunotherapy Elon Musk, a visionary collaboration opportunity by Dr. Sarabi and Grok. Dear Mr Musk: Good morning sir! I would like to bring to your attention the remarkable work of Dr. Patrick Soon-Shiong, who has developed a groundbreaking therapy, Anktiva, capable of supercharging key immune molecules to combat cancer and COVID-19. In a recent discussion with Tucker Carlson, Dr. Soon-Shiong described this advance as akin to the “E=mc²” of medicine—the discovery of “God’s equation,” a biological key that has eluded us for half a century until now. Just as Tesla has revolutionized the automotive and environmental industries, and SpaceX has advanced the expansion of humanity into a multi-planetary species to ensure our long-term survival, Anktiva represents a comparable paradigm shift in medicine, safeguarding human health and endurance. Given your shared commitment to advancing humanity, I respectfully inquire whether you might consider extending your support to Dr. Soon-Shiong in this critical pursuit. Moreover, I propose exploring the integration of Neuralink, employing the stepwise protocol outlined below, in collaboration with Dr. Soon-Shiong. Such a partnership could propel an unprecedented advancement in medicine and the future of humankind. Grok has developed a preliminary conceptual integration of Neuralink to enhance and supercharge IL-15 production 1/7: Identify Target Neural Circuits • Map the hypothalamic paraventricular nucleus (PVN) and dorsal motor nucleus of the vagus • Trace efferent projections from the PVN to the intermediolateral cell column (IML) in the spinal cord. • Identify sympathetic nerve fibers innervating the spleen and lymph nodes. • Map vagus nerve branches terminating in gut-associated lymphoid tissue and the hepatic portal system. 2/7: Implant Neuralink and Integrate with Neural Pathways • Place Neuralink electrodes in the PVN and dorsal motor nucleus of the vagus, using extended threads for subcortical/brainstem access. • Configure for recording/stimulation to modulate autonomic outflow to the IML at thoracic spinal levels. • Establish central control over peripheral pathways (e.g., splenic/vagus nerves) via targeted brain stimulation. 3/7: Develop Stimulation Protocols • Program Neuralink for high-frequency stimulation to the PVN for sympathetic activation. • Apply low-frequency patterned stimulation to the dorsal motor nucleus to engage feedback loops. • Modulate splenic/vagal pathways with phase-locked cycles through central interfaces. 4/7: Initiate Immune Cell Activation • Stimulate pathways to induce IFN-γ and TNF-α release in spleen/lymph nodes. • Trigger IL-15 transcription/translation in dendritic cells, monocytes, and epithelial cells. • Monitor for increased membrane-bound IL-15/IL-15Rα complex formation. 5/7: Enhance Local IL-15 Presentation • Concentrate stimulation at tumor/inflammation sites. • Promote immune cell clustering via chemokine/adhesion molecule induction. • Sustain localized IL-15/IL-15Rα trans-presentation to NK and CD8+ T cells. 6/7: Implement Real-Time Monitoring and Feedback • Record neural/immune biomarkers continuously via Neuralink telemetry. • Adjust stimulation based on IL-15 levels and NK/T cell activity. • Set safety thresholds to avoid excessive immune activation. 7/7: Synchronize with Immunotherapy • Time stimulation with IL-15 superagonists or adoptive therapies. • Evaluate synergies using immune monitoring/imaging. • Optimize based on patient responses. Thank you! #Neuralink #ANKTIVA #Grok #trendingvideo #cancer #medicalnews #health #trendingnow

Dr. Kash Sarabi

16,057 次观看 • 11 个月前

I love your observation and it will make me discuss the remarkable adaptations that prevents giraffes from passing out and suffering brain damage when bending to drink water and when standing up. ADAPTATION 1 Did you know that the distance from the giraffe's heart to its brain is about 2 meters or more? That's more than the average humans height! Pumping blood up to that great distance and working against gravity is not a joke! That's where the giraffe's heart comes in. A giraffe's heart is unique in several ways. First, it is quite large, weighing up to 11kg and measuring about 2 feet long, which is necessary to pump blood up the long neck to the brain. Second, it has thick walls to generate enough pressure to overcome gravity and push the blood up to the head. ADAPTATION 2 Now, let's move to the neck. Before discussing the incredible roles the valves in the jugular veins perform, let's look at what can happen without them, and then the solution. Problem I: When the giraffe bends down to drink, blood rushes downward to the head. Gravity pulls a huge volume of blood toward the brain, which could cause dangerously high pressure in the head and potentially burst vessels or cause other damage. Solution: They have one-way valves in the jugular veins (the large veins in the neck). These prevent blood from rushing backward uncontrollably into the head when lowered. These valves help regulate and slow the downward flow, avoiding a massive pressure surge to the brain. Also, the neck veins can act as temporary blood storage unit, storing over 1 litre of blood. This prevents blood from flooding the brain and also reduces the amount of blood returning to the heart. As a result, the heart pumps with lower pressure while the head is lowered. This buffers the high head pressure that gravity would otherwise cause. Problem II: When they raise their head up immediately after drinking, blood pressure drops sharply to the brain. A sudden drop could starve the brain of oxygen, causing fainting. This is similar to but much more extreme than the dizziness some people feel when standing up quickly. Solution: When the giraffe raises its head, that stored blood rushes back to the heart quickly. The heart responds with a strong, high-pressure beat that immediately pushes blood back up to the brain, preventing a dangerous drop in cerebral pressure. Impressive right?!

Arojinle

33,422 次观看 • 4 个月前

Some microbes carry a protein, called SNIPE, that "chops up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.

Niko McCarty.

20,321 次观看 • 4 个月前

There's something about design that truly makes me happy. Before I was diagnosed with a complete SCI, I loved building thing with my hands and trying to make them unique and beautiful. The accident didn't just take my mobility, it robbed me of my creative drive. I didn't I would ever get that back that was up until Neuralink came into the picture. I was very serious about applying but just couldn't bring myself to do it. Then Noland Arbaugh comes into the picture and I see his video and I saw how passionate he was toward the whole ide and that was like a switch. I want to thank Noland because if I hadn't seen that video I wouldn't be typing this message with my thoughts. So the day I gained control of the device I had the guys install Autodesk Fusion and the first night I had my first part designed by BCI. I have been designing things non-stop since. Now lets talk tools and the first one is the ArcDroid it is a CNC robot that holds a plasma torch and can cut profiles in sheet metal. I have made numerous signs, letters and parts with this and i love it. I have also had the chance to help the local high school install and setup their CNC plasma table. I love being able to share my knowledge with others and show new technology to kids that want to learn. The next one everybody is more familiar with is the Bambu Lab X1C. It is my first 3D printer and I had no idea how dang handy these things were! I can go from thought, Neuralink, Fusion, X1C and poof! You have your part all in a matter of like a hour. I make everything from parts for my wheelchair or RC ✈ to toys for my nephew. These devices have completely changed my life. I now have my creative outlet back and I'm not done looking for new things to try. I'm thinking a laser next!!!😎 Thank you Elon Musk for the opportunity to showcase my skills, I'm extremely grateful🙏

Alex Conley

43,135 次观看 • 7 个月前