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Omega-3 supplementation alone slowed epigenetic aging. Combined with vitamin D and resistance training, it reduced invasive cancer risk by 66%. — Andrew D. Huberman, Ph.D. & Dr. Rhonda Patrick

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180,443 views • 4 months ago •via X (Twitter)

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Dr. Rhonda Patrick takes 2g/day of omega-3. Alone it slows biological aging on epigenetic clocks. Combined with Vitamin D and resistance training together, a Switzerland study showed it also leads to a 66% reduction in invasive cancer risk.

Dr. Rhonda Patrick takes 2g/day of omega-3. Alone it slows biological aging on epigenetic clocks. Combined with Vitamin D and resistance training together, a Switzerland study showed it also leads to a 66% reduction in invasive cancer risk.

Goku

107,617 views • 4 months ago

Omega-3s may be one of the most powerful dietary tools for resolving inflammation and slowing biological aging In a 3-year randomized trial of healthy older adults, omega-3 alone slowed epigenetic aging, while vitamin D and resistance training alone did not But the biggest effect came when all three were combined: omega-3, vitamin D, and resistance training slowed biological aging by about 3.8 months That may sound small, but it reflects a slower pace of aging that could compound over time The combo was also linked to ~40% lower pre-frailty and 61% lower invasive cancer incidence

Omega-3s may be one of the most powerful dietary tools for resolving inflammation and slowing biological aging In a 3-year randomized trial of healthy older adults, omega-3 alone slowed epigenetic aging, while vitamin D and resistance training alone did not But the biggest effect came when all three were combined: omega-3, vitamin D, and resistance training slowed biological aging by about 3.8 months That may sound small, but it reflects a slower pace of aging that could compound over time The combo was also linked to ~40% lower pre-frailty and 61% lower invasive cancer incidence

FoundMyFitness Clips

301,663 views • 3 months ago

Dr. Rhonda Patrick says omega-3 is the single most powerful compound for reducing inflammation in the human body. She broke down why on the Huberman Lab podcast. In a clinical trial out of Switzerland, omega-3 was the only intervention that slowed epigenetic aging clocks. And when combined with Vitamin D and resistance training, the results compounded: • 66% reduction in invasive cancer risk • 90% reduction in sudden cardiac death • 5-year increase in life expectancy at high omega-3 index Patrick says omega-3s work by forming molecules called resolvins and protectins that actively resolve inflammation rather than just suppressing it. They also improve cell membrane fluidity, which directly affects how dopamine and serotonin receptors function in the brain. She recommends 2 grams per day to move from a low omega-3 index to a high one. Patrick says if she could only recommend one supplement to everyone she cares about, it would be omega-3. — Dr. Rhonda Patrick (Dr. Rhonda Patrick) on Andrew Huberman's (Andrew D. Huberman, Ph.D.) podcast PS: If you found this insightful, follow me as I continue sharing unconventional health content just like this.

Dr. Rhonda Patrick says omega-3 is the single most powerful compound for reducing inflammation in the human body. She broke down why on the Huberman Lab podcast. In a clinical trial out of Switzerland, omega-3 was the only intervention that slowed epigenetic aging clocks. And when combined with Vitamin D and resistance training, the results compounded: • 66% reduction in invasive cancer risk • 90% reduction in sudden cardiac death • 5-year increase in life expectancy at high omega-3 index Patrick says omega-3s work by forming molecules called resolvins and protectins that actively resolve inflammation rather than just suppressing it. They also improve cell membrane fluidity, which directly affects how dopamine and serotonin receptors function in the brain. She recommends 2 grams per day to move from a low omega-3 index to a high one. Patrick says if she could only recommend one supplement to everyone she cares about, it would be omega-3. — Dr. Rhonda Patrick (Dr. Rhonda Patrick) on Andrew Huberman's (Andrew D. Huberman, Ph.D.) podcast PS: If you found this insightful, follow me as I continue sharing unconventional health content just like this.

Goku

58,954 views • 4 months ago

.Dr. Rhonda Patrick' top 5 supplements to take: • Omega-3 • Vitamin D • Sulforaphane • Magnesium • Multivitamin

.Dr. Rhonda Patrick' top 5 supplements to take: • Omega-3 • Vitamin D • Sulforaphane • Magnesium • Multivitamin

FoundMyFitness Clips

48,422 views • 1 year ago

5 supplements that give you big bang for your buck: • Omega-3 — a high omega-3 index is linked to 5 extra years of life expectancy, 66% lower Alzheimer’s risk, and slower epigenetic aging • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years • Multivitamin — daily use in older adults was linked to 2.1 years less global brain aging, nearly 5 years less episodic memory aging, and modestly slower epigenetic aging • Magnesium — supports 300+ enzymes involved in DNA repair and sleep, and low intake has been linked to higher cancer risk • Creatine monohydrate — one of the most studied supplements for strength and performance, with 10 grams as a baseline for brain benefits

5 supplements that give you big bang for your buck: • Omega-3 — a high omega-3 index is linked to 5 extra years of life expectancy, 66% lower Alzheimer’s risk, and slower epigenetic aging • Vitamin D — regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity; correcting deficiency can reverse epigenetic age by ~2 years • Multivitamin — daily use in older adults was linked to 2.1 years less global brain aging, nearly 5 years less episodic memory aging, and modestly slower epigenetic aging • Magnesium — supports 300+ enzymes involved in DNA repair and sleep, and low intake has been linked to higher cancer risk • Creatine monohydrate — one of the most studied supplements for strength and performance, with 10 grams as a baseline for brain benefits

FoundMyFitness Clips

514,545 views • 4 months ago

Rhonda Patrick just dropped a bombshell at Natural Products Expo 2026. Just 1 gram of omega-3 a day slows biological aging at the DNA level and reduces invasive cancer risk by 61%. This could be the biggest longevity finding of the decade. Here's everything you need to know:

Rhonda Patrick just dropped a bombshell at Natural Products Expo 2026. Just 1 gram of omega-3 a day slows biological aging at the DNA level and reduces invasive cancer risk by 61%. This could be the biggest longevity finding of the decade. Here's everything you need to know:

Impakt CEO (Winston) - Get paid while getting fit.

156,876 views • 3 months ago

Did you know that living farther from the equator—where sunlight is weaker—has long been linked to higher risks of certain cancers and other conditions? Renowned physician Dr. Paul Marik calls Vitamin D "astonishing," describing it as acting more like a hormone with wide-ranging health benefits. According to Dr. Marik, research indicates Vitamin D plays a role in supporting the body against COVID, depression, Alzheimer's, diabetes, and particularly cancer. He highlights extensive studies showing that lower Vitamin D levels are associated with increased cancer risk, with patterns observed in populations farther from the equator due to reduced UVB exposure—raising risks for cancers like colon, breast, and prostate, as well as Alzheimer's. Encouragingly, Dr. Marik points to evidence suggesting that maintaining adequate Vitamin D through supplementation may help lower cancer development risk. For those diagnosed with cancer, he notes studies where higher-dose Vitamin D supplementation has been associated with improved outcomes, including better chances of remission. This accessible, over-the-counter nutrient continues to be a focus of ongoing research. Always discuss with your healthcare provider before starting supplements or making changes. What are your thoughts on sunlight, Vitamin D, and wellness? Drop a comment!

Did you know that living farther from the equator—where sunlight is weaker—has long been linked to higher risks of certain cancers and other conditions? Renowned physician Dr. Paul Marik calls Vitamin D "astonishing," describing it as acting more like a hormone with wide-ranging health benefits. According to Dr. Marik, research indicates Vitamin D plays a role in supporting the body against COVID, depression, Alzheimer's, diabetes, and particularly cancer. He highlights extensive studies showing that lower Vitamin D levels are associated with increased cancer risk, with patterns observed in populations farther from the equator due to reduced UVB exposure—raising risks for cancers like colon, breast, and prostate, as well as Alzheimer's. Encouragingly, Dr. Marik points to evidence suggesting that maintaining adequate Vitamin D through supplementation may help lower cancer development risk. For those diagnosed with cancer, he notes studies where higher-dose Vitamin D supplementation has been associated with improved outcomes, including better chances of remission. This accessible, over-the-counter nutrient continues to be a focus of ongoing research. Always discuss with your healthcare provider before starting supplements or making changes. What are your thoughts on sunlight, Vitamin D, and wellness? Drop a comment!

Camus

26,327 views • 8 months ago

Dr. Andrew Huberman (Andrew D. Huberman, Ph.D.) explains Andy Galpin, PhD's "3×5" protocol and why cycling low-repetition strength work can improve overall fitness. Here's how it works: - 3-5 exercises per workout - 3-5 working sets for each exercise - 3-5 reps - 3-5 min rest between sets - 3-5x week

Dr. Andrew Huberman (Andrew D. Huberman, Ph.D.) explains Andy Galpin, PhD's "3×5" protocol and why cycling low-repetition strength work can improve overall fitness. Here's how it works: - 3-5 exercises per workout - 3-5 working sets for each exercise - 3-5 reps - 3-5 min rest between sets - 3-5x week

Huberman Lab Clips

98,153 views • 1 year ago

Train your neck It's a form of life insurance This is worth listening to Andrew D. Huberman, Ph.D. details his neck training routine Keep it light Higher reps ~3 sets And try these 2 exercises

Train your neck It's a form of life insurance This is worth listening to Andrew D. Huberman, Ph.D. details his neck training routine Keep it light Higher reps ~3 sets And try these 2 exercises

Huberman Protocols (not Andrew Huberman)

585,457 views • 2 years ago

3 low-effort supplements that have an outsized impact on long-term health: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index (8%+) is associated with longer life expectancy, lower cardiovascular risk, and slower epigenetic aging • Vitamin D — regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity; correcting deficiency may also slow epigenetic aging • Magnesium — roughly half of Americans don’t get enough; it’s a cofactor for 300+ biological processes, including DNA repair and energy production

3 low-effort supplements that have an outsized impact on long-term health: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index (8%+) is associated with longer life expectancy, lower cardiovascular risk, and slower epigenetic aging • Vitamin D — regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity; correcting deficiency may also slow epigenetic aging • Magnesium — roughly half of Americans don’t get enough; it’s a cofactor for 300+ biological processes, including DNA repair and energy production

FoundMyFitness Clips

30,928 views • 28 days ago

We know the medical establishment lied to us about COVID. And according to esteemed physician Dr. Paul Marik, they are also lying to you about the sun. Here's a few things about Vitamin D that Big Pharma doesn't want you to know: #1 - "If you’re vitamin D deficient, it increases your risk of getting cancer.” “There’s a linear relationship between vitamin D deficiency and cancer. And the further you go away from the equator, the less UVB you get, the greater your risk of cancer. This has been well established!” drpaulmarik stressed. #2 - "Vitamin D is highly effective for the treatment of depression.” It’s also “very important for the immune system,” Dr. Marik added. “People don’t like vitamin D. They just don’t like it because if people took vitamin D, [they] would reduce the risk of cancer — would reduce the risk of many diseases." #3 - “If you avoid the sun, it increases your risk of dying [prematurely] by about 25%.” Dr. Marik recommended going into the sun for about 30 minutes a day. He advised not to use sunscreens because “it defeats the purpose.” “In fact, there’s some data that sunscreens increase your risk of melanoma — paradoxically.”

We know the medical establishment lied to us about COVID. And according to esteemed physician Dr. Paul Marik, they are also lying to you about the sun. Here's a few things about Vitamin D that Big Pharma doesn't want you to know: #1 - "If you’re vitamin D deficient, it increases your risk of getting cancer.” “There’s a linear relationship between vitamin D deficiency and cancer. And the further you go away from the equator, the less UVB you get, the greater your risk of cancer. This has been well established!” drpaulmarik stressed. #2 - "Vitamin D is highly effective for the treatment of depression.” It’s also “very important for the immune system,” Dr. Marik added. “People don’t like vitamin D. They just don’t like it because if people took vitamin D, [they] would reduce the risk of cancer — would reduce the risk of many diseases." #3 - “If you avoid the sun, it increases your risk of dying [prematurely] by about 25%.” Dr. Marik recommended going into the sun for about 30 minutes a day. He advised not to use sunscreens because “it defeats the purpose.” “In fact, there’s some data that sunscreens increase your risk of melanoma — paradoxically.”

Vigilant Fox 🦊

169,533 views • 1 year ago

Researchers in Zurich tracked 2,000+ adults over 70 for 3 years to see if aging can be slowed. And it worked better than anyone expected. The protocol helped cut invasive cancer 61% & frailty 40% and slowed aging in their actual DNA. Here's what they did (thread): 🧵

Researchers in Zurich tracked 2,000+ adults over 70 for 3 years to see if aging can be slowed. And it worked better than anyone expected. The protocol helped cut invasive cancer 61% & frailty 40% and slowed aging in their actual DNA. Here's what they did (thread): 🧵

Jake Gilman

65,229 views • 27 days ago

Massive new vitamin D study just dropped — and it’s getting zero mainstream attention A 4-year trial with 25,000 adults across the US (led by 140 researchers) found: Vitamin D3 supplementation significantly preserved telomere length (only 1 year of aging in 4 years). This follows a 10-year Canadian study (12,000 people) showing ~40% reduced dementia risk with vitamin D. The message is clear: Start early, preserve what you have — telomeres don’t reverse once shortened. 2:04 clip inside — game-changing science you need to hear.

Massive new vitamin D study just dropped — and it’s getting zero mainstream attention A 4-year trial with 25,000 adults across the US (led by 140 researchers) found: Vitamin D3 supplementation significantly preserved telomere length (only 1 year of aging in 4 years). This follows a 10-year Canadian study (12,000 people) showing ~40% reduced dementia risk with vitamin D. The message is clear: Start early, preserve what you have — telomeres don’t reverse once shortened. 2:04 clip inside — game-changing science you need to hear.

Camus

1,974,459 views • 7 months ago

We know the medical establishment lied to us about COVID. And according to esteemed physician Dr. Paul Marik, they are also lying to you about the sun. Here's a few things about Vitamin D that Big Pharma doesn't want you to know: #1 - "If you’re vitamin D deficient, it increases your risk of getting cancer.” “There’s a linear relationship between vitamin D deficiency and cancer. And the further you go away from the equator, the less UVB you get, the greater your risk of cancer. This has been well established!” drpaulmarik stressed. #2 - "Vitamin D is highly effective for the treatment of depression.” It’s also “very important for the immune system,” Dr. Marik added. “People don’t like vitamin D. They just don’t like it because if people took vitamin D, [they] would reduce the risk of cancer — would reduce the risk of many diseases." #3 - “If you avoid the sun, it increases your risk of dying [prematurely] by about 25%.” Dr. Marik recommended going into the sun for about 30 minutes a day. He advised not to use sunscreens because “it defeats the purpose.” “In fact, there’s some data that sunscreens increase your risk of melanoma — paradoxically.” The full article featuring Dr. Paul Marik is available to read in the comment below:

We know the medical establishment lied to us about COVID. And according to esteemed physician Dr. Paul Marik, they are also lying to you about the sun. Here's a few things about Vitamin D that Big Pharma doesn't want you to know: #1 - "If you’re vitamin D deficient, it increases your risk of getting cancer.” “There’s a linear relationship between vitamin D deficiency and cancer. And the further you go away from the equator, the less UVB you get, the greater your risk of cancer. This has been well established!” drpaulmarik stressed. #2 - "Vitamin D is highly effective for the treatment of depression.” It’s also “very important for the immune system,” Dr. Marik added. “People don’t like vitamin D. They just don’t like it because if people took vitamin D, [they] would reduce the risk of cancer — would reduce the risk of many diseases." #3 - “If you avoid the sun, it increases your risk of dying [prematurely] by about 25%.” Dr. Marik recommended going into the sun for about 30 minutes a day. He advised not to use sunscreens because “it defeats the purpose.” “In fact, there’s some data that sunscreens increase your risk of melanoma — paradoxically.” The full article featuring Dr. Paul Marik is available to read in the comment below:

The Vigilant Fox 🦊

1,360,679 views • 2 years ago

Vitamin D supplementation was associated with a 40% lower risk of dementia over a decade. After five years, 84% of supplement users were dementia-free compared to just 68% of non-users in a study of over 12,000 people. Vitamin D reduced dementia risk by 33% in adults with mild cognitive impairment or APOE e4, a key genetic risk factor for neurodegenerative diseases. Vitamin D isn’t just a vitamin—it's a steroid hormone regulating over 2,000 genes critical for brain development, neuroplasticity, and inflammation control. Its roles include clearing amyloid beta plaques and tau buildup, boosting neuron survival via neurotrophic factors like BDNF, and enhancing brain connectivity, particularly when paired with exercise. It’s no surprise, then, that higher vitamin D levels are associated with better cognition, larger hippocampal volume, and lower Alzheimer’s risk. Multiple lines of evidence support this. More than 30 large studies have consistently linked low vitamin D levels to a 50–150% increased dementia risk. People genetically prone to low vitamin D—those with genetic variations affecting vitamin D production or metabolism—have a 54% higher dementia risk. Furthermore, supplementing with 800 IU/day of vitamin D improves memory and cognitive function in people with mild cognitive impairment and more serious forms of dementia. To learn more about optimizing vitamin D levels for cognitive health, including underlying brain-protective mechanisms and practical supplementation protocols, see the latest FoundMyFitness video. Link in comments.

Vitamin D supplementation was associated with a 40% lower risk of dementia over a decade. After five years, 84% of supplement users were dementia-free compared to just 68% of non-users in a study of over 12,000 people. Vitamin D reduced dementia risk by 33% in adults with mild cognitive impairment or APOE e4, a key genetic risk factor for neurodegenerative diseases. Vitamin D isn’t just a vitamin—it's a steroid hormone regulating over 2,000 genes critical for brain development, neuroplasticity, and inflammation control. Its roles include clearing amyloid beta plaques and tau buildup, boosting neuron survival via neurotrophic factors like BDNF, and enhancing brain connectivity, particularly when paired with exercise. It’s no surprise, then, that higher vitamin D levels are associated with better cognition, larger hippocampal volume, and lower Alzheimer’s risk. Multiple lines of evidence support this. More than 30 large studies have consistently linked low vitamin D levels to a 50–150% increased dementia risk. People genetically prone to low vitamin D—those with genetic variations affecting vitamin D production or metabolism—have a 54% higher dementia risk. Furthermore, supplementing with 800 IU/day of vitamin D improves memory and cognitive function in people with mild cognitive impairment and more serious forms of dementia. To learn more about optimizing vitamin D levels for cognitive health, including underlying brain-protective mechanisms and practical supplementation protocols, see the latest FoundMyFitness video. Link in comments.

Dr. Rhonda Patrick

245,490 views • 1 year ago

New presentation! At the recent A4M LongevityFest conference (American Academy of Anti-Aging Medicine (A4M)) I discussed how omega-3, vitamin D, and magnesium deficiencies accelerate aging, the life expectancy benefits from improving VO2 max, and the anti-cancer effects of vigorous exercise. Available on YouTube, Spotify, X, and everywhere else. Links in comment. Timestamps: 0:00 - Vitamin D, the gene regulator 5:58 - Vitamin D deficiency & mortality risk 9:24 - Optimal vitamin D levels & supplementation 11:10 - Magnesium deficiency & DNA damage 14:50 - Dangers of inadequate omega-3 intake 17:07 - Why you want your omega-3 index in the 8% range 23:17 - Vigorous exercise is the best longevity drug 24:50 - VO2 max & life expectancy 29:36 - VO2 max protocols 32:27 - Measuring VO2 max 33:34 - Reversing 20 years of heart aging 36:31 - Blood pressure benefits of vigorous exercise 37:48 - BDNF benefits of vigorous exercise 40:58 - Vigorous exercise improves focus & attention 42:11 - Exercise protocols for maximizing BDNF 43:13 - Anti-cancer effects of vigorous exercise 45:30 - How to use exercise snacks to break up sedentary time

New presentation! At the recent A4M LongevityFest conference (American Academy of Anti-Aging Medicine (A4M)) I discussed how omega-3, vitamin D, and magnesium deficiencies accelerate aging, the life expectancy benefits from improving VO2 max, and the anti-cancer effects of vigorous exercise. Available on YouTube, Spotify, X, and everywhere else. Links in comment. Timestamps: 0:00 - Vitamin D, the gene regulator 5:58 - Vitamin D deficiency & mortality risk 9:24 - Optimal vitamin D levels & supplementation 11:10 - Magnesium deficiency & DNA damage 14:50 - Dangers of inadequate omega-3 intake 17:07 - Why you want your omega-3 index in the 8% range 23:17 - Vigorous exercise is the best longevity drug 24:50 - VO2 max & life expectancy 29:36 - VO2 max protocols 32:27 - Measuring VO2 max 33:34 - Reversing 20 years of heart aging 36:31 - Blood pressure benefits of vigorous exercise 37:48 - BDNF benefits of vigorous exercise 40:58 - Vigorous exercise improves focus & attention 42:11 - Exercise protocols for maximizing BDNF 43:13 - Anti-cancer effects of vigorous exercise 45:30 - How to use exercise snacks to break up sedentary time

Dr. Rhonda Patrick

106,103 views • 2 years ago

Dr. Andrew Huberman (Andrew D. Huberman, Ph.D.) shares science-backed habits used by top-performing students to optimize learning and memory: 1. Schedule consistent daily study sessions (3-4 hrs/day, split sessions). 2. Eliminate distractions (phone off, study alone). 3. Teach material to others ("Watch one, do one, teach one"). 4. Regularly quiz yourself. "Testing is one of the best ways to build our knowledge, retain our knowledge and offset forgetting."

Dr. Andrew Huberman (Andrew D. Huberman, Ph.D.) shares science-backed habits used by top-performing students to optimize learning and memory: 1. Schedule consistent daily study sessions (3-4 hrs/day, split sessions). 2. Eliminate distractions (phone off, study alone). 3. Teach material to others ("Watch one, do one, teach one"). 4. Regularly quiz yourself. "Testing is one of the best ways to build our knowledge, retain our knowledge and offset forgetting."

Huberman Lab Clips

313,342 views • 1 year ago

SPEAKING WITH ANDREW HUBERMAN AT EUDEMONIA SUMMIT, PART 2. Last year I had the opportunity to ask Andrew D. Huberman, Ph.D. a question regarding the conversation he had with ☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 on the Tetragrammaton podcast. This year at Eudēmonia I was able to ask Andrew a second question. Since last year, Andrew has had Roger Seheult, MD on the podcast and most recently Dr. Glen Jeffery, a physician and researcher whose work I have been following and sharing. The Andrew D. Huberman, Ph.D. podcast episode with Dr. Glen Jeffery has already been recorded so stay tuned for that. In the meantime, Huberman highlights some important studies Dr. Jeffery has done and the impacts his research has in the video below.

SPEAKING WITH ANDREW HUBERMAN AT EUDEMONIA SUMMIT, PART 2. Last year I had the opportunity to ask Andrew D. Huberman, Ph.D. a question regarding the conversation he had with ☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆 on the Tetragrammaton podcast. This year at Eudēmonia I was able to ask Andrew a second question. Since last year, Andrew has had Roger Seheult, MD on the podcast and most recently Dr. Glen Jeffery, a physician and researcher whose work I have been following and sharing. The Andrew D. Huberman, Ph.D. podcast episode with Dr. Glen Jeffery has already been recorded so stay tuned for that. In the meantime, Huberman highlights some important studies Dr. Jeffery has done and the impacts his research has in the video below.

Jonathan Jarecki

44,813 views • 9 months ago