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Omega-3s Some things you should know: (00:53) Low EPA/DHA intake may drive as many deaths per year as trans fat intake (07:27) Smokers with a high omega-3 index (8%) had the same life expectancy as non-smokers with a low omega-3 index. In other words, smoking was like being deficient... show more

FoundMyFitness Clips

74,218 subscribers

240,850 views • 2 years ago •via X (Twitter)

Anya Rossi• Live Now

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10 Comments

Joe Turco2 years ago

Rhonda is a national treasure. She has saved many, many lives with her rational analysis and presentation. She is one of my faves.

Evlondo Cooper III2 years ago

Stopped taking after hearing most of the oils are rancid.

ThirdEyeOnTheStreet2 years ago

Wow. Worth investing in some cold pressed cod liver oil then

Draja442 years ago

But yet goes and gets the jab..

Bucket_Hat_G2 years ago

Anyone have a link to a recommended omega 3 supplement?

Louis Dallara Photography2 years ago

Carlson's wild Norwegian Cod Liver Oil is the best. 1,100 mg Omega 3s,

Grateful Warrior:2 years ago

OmegaGenics EPA-DHA 2400

John2 years ago

Eat seafood from the sea… supplementation of omega 3’s is hot garbage.

Henry Hood2 years ago

Holy! The smoking comparison is wild! Thanks for sharing this! Any advice on brands or what to look for in a supplement? I currently use Carlson's from Norway.

Marius Schober2 years ago

@yeeseak

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Optimizing your omega-3 intake might be one of the easiest ways to extend your lifespan Research shows having low omega-3 levels (omega-3 index below 4%) poses a mortality risk comparable to smoking Yet nearly 90% of Americans fall short of daily EPA & DHA requirements For most people, taking about 2g per day (EPA + DHA) increases omega-3 index from 4% to 8%—which is associated with a 5-year increase in life expectancy

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Supplementing omega-3 might be one of the simplest ways to extend your lifespan Research from the Framingham study shows a low omega-3 index (under 4%) carries a mortality risk comparable to smoking On top of that, studies show that boosting your omega-3 index from low to optimal (~8%) can increase life expectancy by about five years Yet, nearly 90% of Americans don't meet daily EPA & DHA requirements (~250 mg/day)—easily corrected by eating fish or supplementing with fish oil

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Higher omega-3 status is associated with dramatically lower Alzheimer’s risk. People with a high omega-3 index (~10%) have about a 50% lower risk of Alzheimer’s disease compared with those at the low end (~4%). Other studies have reported a dose-dependent relationship - for every 100 mg/day increase in omega-3 intake, Alzheimer’s disease and cognitive decline risk falls by about 10%. This is still largely correlative data. But when you combine a large risk reduction with a dose-dependent trend, it becomes hard to ignore. Practically, it may take roughly 2 g/day of omega-3s to move from a low omega-3 index toward that higher, more protective range.

Higher omega-3 status is associated with dramatically lower Alzheimer’s risk. People with a high omega-3 index (~10%) have about a 50% lower risk of Alzheimer’s disease compared with those at the low end (~4%). Other studies have reported a dose-dependent relationship - for every 100 mg/day increase in omega-3 intake, Alzheimer’s disease and cognitive decline risk falls by about 10%. This is still largely correlative data. But when you combine a large risk reduction with a dose-dependent trend, it becomes hard to ignore. Practically, it may take roughly 2 g/day of omega-3s to move from a low omega-3 index toward that higher, more protective range.

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125,668 views • 5 months ago

Taking ~2 grams/day of fish oil is enough to move most people from a low omega-3 index (~4%) to the optimal range (~8%), with major benefits: • ~90% lower risk of sudden cardiac death • ~5-year increase in life expectancy (at higher omega-3 index levels) • Lower risk of dementia and other neurodegenerative disease • ~30% reduced heart attack risk (VITAL study) • ~25% fewer adverse cardiac events (REDUCE-IT trial) Concerns about “oxidized fish oil” are often overstated Quality definitely matters, but the bigger risk is not getting enough omega-3s at all

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What form of omega-3 you take matters. And I'm not just talking walnuts (ALA) and salmon (EPA/DHA) here. Lyso-DHA is a special form that gets privileged access to the brain. In controlled dosing experiments, Lyso-DHA boost brain DHA and (BDNF) far more than conventional DHA, whereas conventional DHA tends more towards fat tissue. For a deeper dive, see the letter linked at the end of the quoted thread.

What form of omega-3 you take matters. And I'm not just talking walnuts (ALA) and salmon (EPA/DHA) here. Lyso-DHA is a special form that gets privileged access to the brain. In controlled dosing experiments, Lyso-DHA boost brain DHA and (BDNF) far more than conventional DHA, whereas conventional DHA tends more towards fat tissue. For a deeper dive, see the letter linked at the end of the quoted thread.

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23,532 views • 9 months ago

Boosting your omega-3 levels could cut your Alzheimer's risk in half An omega-3 index (a long-term marker of omega-3 intake) of 8% or higher is linked to a staggering 50% lower chance of developing Alzheimer's disease compared to lower levels (4% or less) Even more remarkably, reaching this threshold adds roughly 5 extra years without cognitive impairment As an added bonus, high omega-3 intake is also linked to greater hippocampal brain volume, a critical region for learning and memory that typically shrinks as Alzheimer's disease progresses

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3 low-effort supplements that have an outsized impact on long-term health: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index (8%+) is associated with longer life expectancy, lower cardiovascular risk, and slower epigenetic aging • Vitamin D — regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity; correcting deficiency may also slow epigenetic aging • Magnesium — roughly half of Americans don’t get enough; it’s a cofactor for 300+ biological processes, including DNA repair and energy production

3 low-effort supplements that have an outsized impact on long-term health: • Omega-3s — 2 g/day is a strong starting point; a high omega-3 index (8%+) is associated with longer life expectancy, lower cardiovascular risk, and slower epigenetic aging • Vitamin D — regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity; correcting deficiency may also slow epigenetic aging • Magnesium — roughly half of Americans don’t get enough; it’s a cofactor for 300+ biological processes, including DNA repair and energy production

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30,928 views • 2 months ago

Taking omega-3s with a meal helps blunt the inflammatory spike that happens every time you eat Even a healthy meal triggers a postprandial inflammatory response and a surge of LPS from the gut, and omega-3 has been shown to dampen that effect At the same time, EPA and DHA are fat-soluble, so taking them with a higher-fat meal improves absorption versus taking them on an empty stomach

Taking omega-3s with a meal helps blunt the inflammatory spike that happens every time you eat Even a healthy meal triggers a postprandial inflammatory response and a surge of LPS from the gut, and omega-3 has been shown to dampen that effect At the same time, EPA and DHA are fat-soluble, so taking them with a higher-fat meal improves absorption versus taking them on an empty stomach

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45,402 views • 7 months ago

Dr. Rhonda Patrick says omega-3 is the single most powerful compound for reducing inflammation in the human body. She broke down why on the Huberman Lab podcast. In a clinical trial out of Switzerland, omega-3 was the only intervention that slowed epigenetic aging clocks. And when combined with Vitamin D and resistance training, the results compounded: • 66% reduction in invasive cancer risk • 90% reduction in sudden cardiac death • 5-year increase in life expectancy at high omega-3 index Patrick says omega-3s work by forming molecules called resolvins and protectins that actively resolve inflammation rather than just suppressing it. They also improve cell membrane fluidity, which directly affects how dopamine and serotonin receptors function in the brain. She recommends 2 grams per day to move from a low omega-3 index to a high one. Patrick says if she could only recommend one supplement to everyone she cares about, it would be omega-3. — Dr. Rhonda Patrick (Dr. Rhonda Patrick) on Andrew Huberman's (Andrew D. Huberman, Ph.D.) podcast PS: If you found this insightful, follow me as I continue sharing unconventional health content just like this.

Dr. Rhonda Patrick says omega-3 is the single most powerful compound for reducing inflammation in the human body. She broke down why on the Huberman Lab podcast. In a clinical trial out of Switzerland, omega-3 was the only intervention that slowed epigenetic aging clocks. And when combined with Vitamin D and resistance training, the results compounded: • 66% reduction in invasive cancer risk • 90% reduction in sudden cardiac death • 5-year increase in life expectancy at high omega-3 index Patrick says omega-3s work by forming molecules called resolvins and protectins that actively resolve inflammation rather than just suppressing it. They also improve cell membrane fluidity, which directly affects how dopamine and serotonin receptors function in the brain. She recommends 2 grams per day to move from a low omega-3 index to a high one. Patrick says if she could only recommend one supplement to everyone she cares about, it would be omega-3. — Dr. Rhonda Patrick (Dr. Rhonda Patrick) on Andrew Huberman's (Andrew D. Huberman, Ph.D.) podcast PS: If you found this insightful, follow me as I continue sharing unconventional health content just like this.

Goku

59,076 views • 5 months ago

Resolving inflammation and preserving membrane fluidity are two powerful ways omega-3s support cardiovascular health. Chronic inflammation is one of the main drivers of atherosclerosis, which is likely why a higher omega-3 index has been associated with up to a 40% lower risk of cardiovascular events in observational studies. This clip comes from my presentation at Expo West earlier this year, where I discussed the many ways omega-3 fatty acids support cardiovascular health.

Resolving inflammation and preserving membrane fluidity are two powerful ways omega-3s support cardiovascular health. Chronic inflammation is one of the main drivers of atherosclerosis, which is likely why a higher omega-3 index has been associated with up to a 40% lower risk of cardiovascular events in observational studies. This clip comes from my presentation at Expo West earlier this year, where I discussed the many ways omega-3 fatty acids support cardiovascular health.

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60,212 views • 7 days ago