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Retatrutide is the ultimate gateway peptide. Once you try it, everything changes. Appetite obliterated, fat melting off, energy steady, and it opens the door to the full biohacking stack. I’m down 31 lbs in 11 weeks. This isn’t just another GLP-1 — it’s next level.

Biotides

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23,346 Aufrufe • vor 1 Monat •via X (Twitter)

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This is the COMPLETE Peptide Tier List compilation — Parts 1 through 3 combined into one deep dive. We break down the most talked-about compounds in fitness, longevity, anti-aging, and fat loss: Semaglutide, Tirzepatide, Retatrutide, Mazdutide, Growth Hormone (HGH), HCG, IGF-1 LR3, Tesamorelin, Sermorelin, CJC-1295, Ipamorelin, BPC-157, TB-500, NAD+, Melanotan, Selank, SEMAX, MOTS-C, Kisspeptin, Insulin, and more. If you’ve ever searched: • Best peptides for fat loss • Best peptide for muscle growth • GLP-1 vs growth hormone • Is BPC-157 legit? • Is insulin dangerous for bodybuilding? This thread answers it. We cover: ✔️ Real human data vs hype ✔️ Fat loss vs muscle-building compounds ✔️ GLP-1 agonists (semaglutide, tirzepatide, retatrutide) ✔️ Growth hormone secretagogues ✔️ Longevity + nootropic peptides ✔️ The compounds people massively overestimate Some are revolutionary. Some are promising. Some are pure internet fantasy. This isn’t bro science. It’s mechanism + data + real-world application. If you’re considering peptides for weight loss, muscle gain, performance, anti-aging, or cognition — read this before you inject anything. 👇 Which compound surprised you the most?

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Patience isn’t just waiting it’s strength under control. It’s the ability to trust the process, to stay steady when everything in you wants to rush. Without patience, desire turns into frustration. With it, everything you seek comes at the right time, and nothing can be taken from you.

Patience isn’t just waiting it’s strength under control. It’s the ability to trust the process, to stay steady when everything in you wants to rush. Without patience, desire turns into frustration. With it, everything you seek comes at the right time, and nothing can be taken from you.

𖣂JIK𖣂

159,707 Aufrufe • vor 10 Monaten

There's a question that keeps coming up: is retatrutide better than tirzepatide? In my experience, this is the wrong question. It's like asking whether steak or chicken is better. Steak is arguably more nutrient-dense, but some people do better on chicken, and there's no reason you wouldn't vary your protein sources. It's the same with GLPs. It's not either/or, you have to experiment. > Tirzepatide is a dual agonist. It hits GLP-1 and GIP receptors. > Retatrutide is a triple agonist. It hits GLP-1, GIP, and glucagon receptors. That glucagon piece is the key difference. It changes how your body uses fuel in a way tirzepatide simply doesn't. In clinical trials, retatrutide produced 24% average weight loss in 48 weeks. Tirzepatide produced 21% in 72 weeks. Reta produced better results in almost half the time. The glucagon receptor drives thermogenesis and fat oxidation, which you don't get with a dual agonist. But retatrutide comes with a tradeoff. It raises resting heart rate by 5-10 BPM, driven by the glucagon receptor, and happens at every dose level. Reta peaks around week 24 and reverses when you stop. This doesn't happen with tirzepatide. And that's exactly why you shouldn't be on either of these indefinitely. The problem is that most people are scared to cycle off because they've heard the horror stories about weight rebound. As a result, they stay on way too long. This isn't medical advice, but I believe the right approach is to be 12-16 weeks on, 8-10 weeks off. You cycle, monitor, and adjust. If you don't know how to properly come off a GLP, you have no business being on one. On top of that, if you're running the experiment but not tracking it, you're wasting it. - Get labs done: fasting insulin, blood glucose, A1C, etc. - Wear a tracker: monitor heart rate and HRV These compounds impact metabolic markers that matter way more than bodyweight. If you have weight to lose and you're interested in GLPs, run at least one cycle of each. See how your body responds to retatrutide. Then see how it responds to tirzepatide. Compare the data, and that's how you'll find what works. Because in performance healthcare, data wins, not the math. Comment "FATLOSS" below, and I'll send you my 70-page Peptide Bible. P.S. None of this is medical advice nor a recommendation.

There's a question that keeps coming up: is retatrutide better than tirzepatide? In my experience, this is the wrong question. It's like asking whether steak or chicken is better. Steak is arguably more nutrient-dense, but some people do better on chicken, and there's no reason you wouldn't vary your protein sources. It's the same with GLPs. It's not either/or, you have to experiment. > Tirzepatide is a dual agonist. It hits GLP-1 and GIP receptors. > Retatrutide is a triple agonist. It hits GLP-1, GIP, and glucagon receptors. That glucagon piece is the key difference. It changes how your body uses fuel in a way tirzepatide simply doesn't. In clinical trials, retatrutide produced 24% average weight loss in 48 weeks. Tirzepatide produced 21% in 72 weeks. Reta produced better results in almost half the time. The glucagon receptor drives thermogenesis and fat oxidation, which you don't get with a dual agonist. But retatrutide comes with a tradeoff. It raises resting heart rate by 5-10 BPM, driven by the glucagon receptor, and happens at every dose level. Reta peaks around week 24 and reverses when you stop. This doesn't happen with tirzepatide. And that's exactly why you shouldn't be on either of these indefinitely. The problem is that most people are scared to cycle off because they've heard the horror stories about weight rebound. As a result, they stay on way too long. This isn't medical advice, but I believe the right approach is to be 12-16 weeks on, 8-10 weeks off. You cycle, monitor, and adjust. If you don't know how to properly come off a GLP, you have no business being on one. On top of that, if you're running the experiment but not tracking it, you're wasting it. - Get labs done: fasting insulin, blood glucose, A1C, etc. - Wear a tracker: monitor heart rate and HRV These compounds impact metabolic markers that matter way more than bodyweight. If you have weight to lose and you're interested in GLPs, run at least one cycle of each. See how your body responds to retatrutide. Then see how it responds to tirzepatide. Compare the data, and that's how you'll find what works. Because in performance healthcare, data wins, not the math. Comment "FATLOSS" below, and I'll send you my 70-page Peptide Bible. P.S. None of this is medical advice nor a recommendation.

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Clavicular EXPLAINS Ozempic side effects and REVEALS his Retatrutide protocol for the BEST results 😳👀 "The thing about Ozempic is it's like... it's only a single agonist and it hits the GLP-1 super hard, so all you get is nausea, uh, indigestion, and GI issues." "Whereas Reta is a lot more selective, right? It's going to hit those three receptors... you don't actually feel physically nauseous. You just have no appetite..." "I'm on Reta. Like I'm on 10 mg every five days... It blunts my appetite entirely, uh, and I'm—I'm completely used to it at this point."

Clavicular EXPLAINS Ozempic side effects and REVEALS his Retatrutide protocol for the BEST results 😳👀 "The thing about Ozempic is it's like... it's only a single agonist and it hits the GLP-1 super hard, so all you get is nausea, uh, indigestion, and GI issues." "Whereas Reta is a lot more selective, right? It's going to hit those three receptors... you don't actually feel physically nauseous. You just have no appetite..." "I'm on Reta. Like I'm on 10 mg every five days... It blunts my appetite entirely, uh, and I'm—I'm completely used to it at this point."

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Everything in Asia is so ridiculously convenient In this case Singapore You tap your keycard, the door automatically opens, and then it also automatically calls the elevator for you Just absolute High IQ thinking to make everyone's daily life easier

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@levelsio

3,129,410 Aufrufe • vor 1 Jahr

RETATRUTIDE is NOT JUST for WEIGHT LOSS… …and the fact that that’s what everyone is obsessing over tells me we’re still missing the point. 🙃 Because what I’m looking at? It’s not just the scale. It’s what’s happening underneath it. We’re talking 24% body weight reduction in trials… sure. BUT ALSO: 47% drop in inflammatory markers in 12 weeks. 2.1% drop in HbA1c. 42% reduction in visceral fat (the dangerous kind hugging your organs). 🫁 And then it gets uncomfortable… 31% lower cardiovascular mortality. 28% fewer heart attacks. 22% fewer strokes. Like… pause there. Because if this was just about weight loss… those numbers wouldn’t exist. This is metabolism. This is inflammation. This is mitochondrial signaling. 🧬 And THIS is where I start side-eyeing the narrative. Because you’ve been told this is about “calories” and “willpower.” Meanwhile your body is sitting there like— “Hey… I’m inflamed. I’m insulin resistant. I’m storing for a reason.” 👀 And instead of asking why… We’ve been handed drugs and told to shrink. But here’s the part nobody’s talking about… What happens when you stop? With semaglutide (Ozempic)… about 72% of people regain the weight. Tirzepatide? Around 60%. Retatrutide? ONLY 5–10%. That’s not a small difference. That’s a completely different conversation. Because now we’re NOT just talking about weight suppression… We’re talking about whether the terrain (esp hormones and body talk) actually changed. And if you’ve ever felt like you’re doing everything right… but your body keeps pulling you back… this matters more than you think. Because your body isn’t trying to sabotage you. It’s responding to something deeper. If you want me to break down what this actually means… and how peptides are shifting the entire conversation— Comment PEPTIDES and I’ll send you the full breakdown. 💡 #peptides #biohacking #womenshealth #hormones #healthandwellbeing

RETATRUTIDE is NOT JUST for WEIGHT LOSS… …and the fact that that’s what everyone is obsessing over tells me we’re still missing the point. 🙃 Because what I’m looking at? It’s not just the scale. It’s what’s happening underneath it. We’re talking 24% body weight reduction in trials… sure. BUT ALSO: 47% drop in inflammatory markers in 12 weeks. 2.1% drop in HbA1c. 42% reduction in visceral fat (the dangerous kind hugging your organs). 🫁 And then it gets uncomfortable… 31% lower cardiovascular mortality. 28% fewer heart attacks. 22% fewer strokes. Like… pause there. Because if this was just about weight loss… those numbers wouldn’t exist. This is metabolism. This is inflammation. This is mitochondrial signaling. 🧬 And THIS is where I start side-eyeing the narrative. Because you’ve been told this is about “calories” and “willpower.” Meanwhile your body is sitting there like— “Hey… I’m inflamed. I’m insulin resistant. I’m storing for a reason.” 👀 And instead of asking why… We’ve been handed drugs and told to shrink. But here’s the part nobody’s talking about… What happens when you stop? With semaglutide (Ozempic)… about 72% of people regain the weight. Tirzepatide? Around 60%. Retatrutide? ONLY 5–10%. That’s not a small difference. That’s a completely different conversation. Because now we’re NOT just talking about weight suppression… We’re talking about whether the terrain (esp hormones and body talk) actually changed. And if you’ve ever felt like you’re doing everything right… but your body keeps pulling you back… this matters more than you think. Because your body isn’t trying to sabotage you. It’s responding to something deeper. If you want me to break down what this actually means… and how peptides are shifting the entire conversation— Comment PEPTIDES and I’ll send you the full breakdown. 💡 #peptides #biohacking #womenshealth #hormones #healthandwellbeing

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Andrew Huberman just broke down the next wave of weight-loss drugs on Gwyneth Paltrow’s goop podcast. He says the new triple agonist Retatrutide (currently in trials) is a big step up from Ozempic and Mounjaro. It hits three pathways (GLP-1 + glucagon + GIP) more gently, leading to significant weight loss with potentially less muscle loss and fewer side effects. People are already hunting for gray/black market versions. Early trial data on Retatrutide showed participants losing up to 24% of their body weight over 48 weeks, with notably better muscle preservation compared to earlier GLP-1 drugs when combined with resistance training. These next-generation drugs are becoming more targeted, but access, safety, and proper use remain key issues. This conversation made the rapid evolution of these drugs feel very real. It’s wild how fast this space is moving. What’s your take on the new generation of GLP drugs like Retatrutide?

Andrew Huberman just broke down the next wave of weight-loss drugs on Gwyneth Paltrow’s goop podcast. He says the new triple agonist Retatrutide (currently in trials) is a big step up from Ozempic and Mounjaro. It hits three pathways (GLP-1 + glucagon + GIP) more gently, leading to significant weight loss with potentially less muscle loss and fewer side effects. People are already hunting for gray/black market versions. Early trial data on Retatrutide showed participants losing up to 24% of their body weight over 48 weeks, with notably better muscle preservation compared to earlier GLP-1 drugs when combined with resistance training. These next-generation drugs are becoming more targeted, but access, safety, and proper use remain key issues. This conversation made the rapid evolution of these drugs feel very real. It’s wild how fast this space is moving. What’s your take on the new generation of GLP drugs like Retatrutide?

Camus

358,545 Aufrufe • vor 2 Monaten

You can say anything in the NBA…until it’s biblical. Then the temperature changes, and Jaden Ivey just proved it. This isn’t about basketball. It’s about control. Read this: 👇🏾👇🏾👇🏾

You can say anything in the NBA…until it’s biblical. Then the temperature changes, and Jaden Ivey just proved it. This isn’t about basketball. It’s about control. Read this: 👇🏾👇🏾👇🏾

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Retatrutide isn't supposed to be everywhere. Touted as the next generation in the GLP-1 craze, it's an experimental weight-loss drug that is not authorized outside of clinical trials. The Food and Drug Administration hasn't reviewed whether it is safe and effective, which is the legal path for prescription drugs to come to market. And yet retatrutide is for sale all over the internet, a phenomenon with no modern precedent. Adam Yamaguchi

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CBS News

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I’m dancing on the same soil you Khamenei.ir tried to stain. This isn’t just “New York energy.” It’s Iranian women defiance. 💃🏻💃🏻🌻🌻 Yes you ordered the IRGC to kill me, for comparing forced hijab to the Berlin Wall and now The Wall is falling in the streets of Iran because Iranian women are tearing it down with their hair, their courage, and their dance. Next up: your regime.

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The secret is out. I’m proud to be a part of GameScript. ❤️ This gives me the platform to give you so much more across Soccer, NFL, NBA & UFC. Try it out for just $1. Join here 👉🏼 Time to go to the next level.

The secret is out. I’m proud to be a part of GameScript. ❤️ This gives me the platform to give you so much more across Soccer, NFL, NBA & UFC. Try it out for just $1. Join here 👉🏼 Time to go to the next level.

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Tyronn Lue, to janis carr on his frustration level: “The last five years, I’ve been able to figure it out. But this year it’s been tough. … I’m just really pissed off more than frustrated because it happens every year and it’s just tough to try to continue getting through it.”

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Is it my eyes or everything is looking alive and fresh in this soup🧐🧐 Apparently this is a Ghanaian delicacy. I'll recommend you try it out when next you travel to Ghana. Will you be eating it or doubling it and passing to the next person?

NaijaFarmer

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