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The most beautiful molecular recorder 😍 GEMINI is a self-assembling protein system that records cellular events as physical layers, readable via imaging. Achieves down to 15 min resolution and works nicely in vivo! From Dingchang Lin's lab in nature

Julia Bauman

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18,437 次观看 • 3 个月前 •via X (Twitter)

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PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution

PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution

Dr. Filippo Cademartiri

11,820 次观看 • 1 年前

A new Nature paper from Johns Hopkins (by Prof. Lin Dingchang Lin ) just solved one of the hardest problems in biology: how do you record what every cell in a tissue experienced over time, not just what it looks like right now? The answer: GEMINI — Granularly Expanding Memory for Intracellular Narrative Integration. It works exactly like tree rings. Cells are genetically engineered to express a computationally designed protein assembly. As the assembly grows inside the cell, it captures cellular activity as fluorescent ring patterns — each ring a timestamp, each ring's properties encoding signal intensity. Look at a cross-section under a microscope and you can read the cell's history backward, with ~15-minute resolution. The key: cells build the recorder themselves. GEMINI doesn't interfere with normal function — it just quietly writes. What they demonstrated: In a full tumor xenograft, GEMINI captured every cancer cell's activity history across the entire tumor while it continued to grow normally. For the first time, researchers can look back and see how different regions of the same tumor responded differently to therapy over time — not snapshots, but film. In a mouse brain, GEMINI recorded neural activity dynamics without disrupting behavior, coordination, or memory. It could temporally resolve the history of a brain seizure. Why this matters: Every tool we have in biology gives you state — what the cell looks like now. Sequencing, imaging, proteomics — all snapshots. GEMINI gives you trajectory. It's the difference between a photograph and a video, applied to every cell in an organ simultaneously. The team is explicit that AI-based decoding tools will be central to reading GEMINI's output at whole-brain scale. This is the data layer that makes temporal single-cell atlases possible. Paper: Congratulations Dingchang Lin

A new Nature paper from Johns Hopkins (by Prof. Lin Dingchang Lin ) just solved one of the hardest problems in biology: how do you record what every cell in a tissue experienced over time, not just what it looks like right now? The answer: GEMINI — Granularly Expanding Memory for Intracellular Narrative Integration. It works exactly like tree rings. Cells are genetically engineered to express a computationally designed protein assembly. As the assembly grows inside the cell, it captures cellular activity as fluorescent ring patterns — each ring a timestamp, each ring's properties encoding signal intensity. Look at a cross-section under a microscope and you can read the cell's history backward, with ~15-minute resolution. The key: cells build the recorder themselves. GEMINI doesn't interfere with normal function — it just quietly writes. What they demonstrated: In a full tumor xenograft, GEMINI captured every cancer cell's activity history across the entire tumor while it continued to grow normally. For the first time, researchers can look back and see how different regions of the same tumor responded differently to therapy over time — not snapshots, but film. In a mouse brain, GEMINI recorded neural activity dynamics without disrupting behavior, coordination, or memory. It could temporally resolve the history of a brain seizure. Why this matters: Every tool we have in biology gives you state — what the cell looks like now. Sequencing, imaging, proteomics — all snapshots. GEMINI gives you trajectory. It's the difference between a photograph and a video, applied to every cell in an organ simultaneously. The team is explicit that AI-based decoding tools will be central to reading GEMINI's output at whole-brain scale. This is the data layer that makes temporal single-cell atlases possible. Paper: Congratulations Dingchang Lin

Bo Wang

85,095 次观看 • 4 个月前

The people of Mwihoko in Kiambu County made away with the black box of the AMREF plane that crashed yesterday. For starters, the black box is the most survivable part of the aircraft, which investigators use to reconstruct the events that lead up to a plane crash. The black box is made up of the cockpit voice recorder and the flight data recorder. The cockpit voice recorder collects radio transmissions and sounds such as the pilot’s voices and engine noises, as well as listens to conversations between the pilots and crew and communications with air traffic control. While the flight data recorder monitors a plane’s altitude, airspeed and heading

The people of Mwihoko in Kiambu County made away with the black box of the AMREF plane that crashed yesterday. For starters, the black box is the most survivable part of the aircraft, which investigators use to reconstruct the events that lead up to a plane crash. The black box is made up of the cockpit voice recorder and the flight data recorder. The cockpit voice recorder collects radio transmissions and sounds such as the pilot’s voices and engine noises, as well as listens to conversations between the pilots and crew and communications with air traffic control. While the flight data recorder monitors a plane’s altitude, airspeed and heading

Bianca™

87,135 次观看 • 11 个月前

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

Alex Rives

655,646 次观看 • 1 个月前

Dr. Robert Redfield, the former CDC Director, talks about three suspicious events that took place at the Wuhan lab in September 2019: "In Sept. 2019, three things happened in that lab. One is they deleted the sequences. Highly irregular, researchers don't like to do that. The second thing is they changed the command and control from civilian to military. Highly unusual. The third, which is very telling, is they let a contractor redo the ventilation system in that laboratory. Clearly, there was strong evidence that a significant event happened in that laboratory in September."

Dr. Robert Redfield, the former CDC Director, talks about three suspicious events that took place at the Wuhan lab in September 2019: "In Sept. 2019, three things happened in that lab. One is they deleted the sequences. Highly irregular, researchers don't like to do that. The second thing is they changed the command and control from civilian to military. Highly unusual. The third, which is very telling, is they let a contractor redo the ventilation system in that laboratory. Clearly, there was strong evidence that a significant event happened in that laboratory in September."

KanekoaTheGreat

4,109,136 次观看 • 3 年前

If you're serious about detoxing at the cellular level, hydrogen water should be in your daily routine. Hydrogen is the smallest, most abundant element in the universe, and it works as a selective antioxidant, neutralizing the dangerous oxidative stress that accelerates aging and disease without disrupting your body’s natural healing processes. I use H2Tab daily. Less than $1 a day for a biohack that goes straight to work where it matters most, your mitochondria and cellular health. Get yours here:

If you're serious about detoxing at the cellular level, hydrogen water should be in your daily routine. Hydrogen is the smallest, most abundant element in the universe, and it works as a selective antioxidant, neutralizing the dangerous oxidative stress that accelerates aging and disease without disrupting your body’s natural healing processes. I use H2Tab daily. Less than $1 a day for a biohack that goes straight to work where it matters most, your mitochondria and cellular health. Get yours here:

Gary Brecka

49,455 次观看 • 1 年前

Demis Hassabis confirmed every frontier AI lab is working on recursive self-improvement and in the same sentence said the safety risk of removing humans from the loop entirely keeps him up at night. That combination should stop you. The CEO of Google DeepMind just confirmed that the thing most people treat as a theoretical future risk is already the active focus of every serious lab on earth right now. He explained why it works in coding and math. The feedback loop is fast. You can verify whether an answer is correct almost instantly. You can generate synthetic training data from it. The loop closes quickly and cleanly. Then he said where it breaks down. In biology, chemistry and physics. Any domain where verifying a hypothesis requires a physical experiment in the real world. The loop does not close in seconds. It closes in weeks or months. Geoffrey Hinton said in his Nobel lecture that recursive self-improvement is the development he fears most and that once started it may not be possible to stop. Hassabis is not pushing back on that. He is describing the guardrails labs are building around a process they are already running. Every lab has to think carefully about the safety of a process where no human is in the loop. He said that as a constraint they are navigating right now. The question they are sitting with is how much of it to let run without a human watching. (Watch the full interview on YouTube at Two Minute Papers channel)

Demis Hassabis confirmed every frontier AI lab is working on recursive self-improvement and in the same sentence said the safety risk of removing humans from the loop entirely keeps him up at night. That combination should stop you. The CEO of Google DeepMind just confirmed that the thing most people treat as a theoretical future risk is already the active focus of every serious lab on earth right now. He explained why it works in coding and math. The feedback loop is fast. You can verify whether an answer is correct almost instantly. You can generate synthetic training data from it. The loop closes quickly and cleanly. Then he said where it breaks down. In biology, chemistry and physics. Any domain where verifying a hypothesis requires a physical experiment in the real world. The loop does not close in seconds. It closes in weeks or months. Geoffrey Hinton said in his Nobel lecture that recursive self-improvement is the development he fears most and that once started it may not be possible to stop. Hassabis is not pushing back on that. He is describing the guardrails labs are building around a process they are already running. Every lab has to think carefully about the safety of a process where no human is in the loop. He said that as a constraint they are navigating right now. The question they are sitting with is how much of it to let run without a human watching. (Watch the full interview on YouTube at Two Minute Papers channel)

Ihtesham Ali

67,788 次观看 • 23 天前

This is a Kinesin Molecule. These little molecular machines are commonly referred to as the "workhorse" of the cell, hauling important cargo like organelles, proteins and other cellular structures to their proper location within the cell. Kinesins are very clear & undeniable evidence of the intelligent design in Life. Kinesins are complex molecular machines, made up of 4 total proteins, each between 500-1,300 amino acids in length. If these aa sequences are not perfectly aligned from the beginning, Kinesin never forms, and cellular life would be unable to survive. Here is how they work: When a new protein, organelle, or other cellular structure is created in the Cytosol of the cell, they are constructed with built-in "binding tags," which are like shipping labels that bind to other protein molecules called Adaptor or Scaffold Proteins. These Adaptor/Scaffold Proteins then attach to the Kinesin's tail, which activates them, and then the Kinesin is guided along the microtubule track to its to its final destination. Kinesin walk on self-assembling tracks of other proteins, called microtubules, moving cargo from the inner area of the cell where they are constructed to the outer edges where they function. This is a complex & sophisticated interdependent network of molecular machines, all relying on one another to function properly for the health of the cell. This Intracellular Transportation system MUST be fully functional from the beginning - with all these working parts, or all of it fails, and the cell dies. Without this entire functioning system, Life could not exist. And the Kinesin is the centerpiece to all of it. Experiments have shown that disrupting Kinesin activity has catastrophic consequences. This type of nano-precision is an obvious example of designed engineering. Blind, unguided evolutionary processes cannot plan ahead and create complex informational highways for precision transportation. The proposed evolutionary explanation is simply "co-option." A nebulous term which basically amounts to, "We don't know how it evolved, but it must have evolved from some other thing that was similar in the past." No observational data supports evolutionary co-option. It's absurd to believe any part of this was built by blind chance. Everything in the cell points to Intelligent Design.

This is a Kinesin Molecule. These little molecular machines are commonly referred to as the "workhorse" of the cell, hauling important cargo like organelles, proteins and other cellular structures to their proper location within the cell. Kinesins are very clear & undeniable evidence of the intelligent design in Life. Kinesins are complex molecular machines, made up of 4 total proteins, each between 500-1,300 amino acids in length. If these aa sequences are not perfectly aligned from the beginning, Kinesin never forms, and cellular life would be unable to survive. Here is how they work: When a new protein, organelle, or other cellular structure is created in the Cytosol of the cell, they are constructed with built-in "binding tags," which are like shipping labels that bind to other protein molecules called Adaptor or Scaffold Proteins. These Adaptor/Scaffold Proteins then attach to the Kinesin's tail, which activates them, and then the Kinesin is guided along the microtubule track to its to its final destination. Kinesin walk on self-assembling tracks of other proteins, called microtubules, moving cargo from the inner area of the cell where they are constructed to the outer edges where they function. This is a complex & sophisticated interdependent network of molecular machines, all relying on one another to function properly for the health of the cell. This Intracellular Transportation system MUST be fully functional from the beginning - with all these working parts, or all of it fails, and the cell dies. Without this entire functioning system, Life could not exist. And the Kinesin is the centerpiece to all of it. Experiments have shown that disrupting Kinesin activity has catastrophic consequences. This type of nano-precision is an obvious example of designed engineering. Blind, unguided evolutionary processes cannot plan ahead and create complex informational highways for precision transportation. The proposed evolutionary explanation is simply "co-option." A nebulous term which basically amounts to, "We don't know how it evolved, but it must have evolved from some other thing that was similar in the past." No observational data supports evolutionary co-option. It's absurd to believe any part of this was built by blind chance. Everything in the cell points to Intelligent Design.

Divinely Designed

15,877 次观看 • 6 个月前

This simulated Earth matrix is layers upon infinite layers of microcsoms and macrocosms in the physical 3D plane. The Golden Ratio and Fibonacci sequence is seen all throughout nature in small scales like seashells, pinecones, the human ear and even as ultra small as human DNA itself and extending to much larger scales like The Earth/moon ratio seen in this video. Yes, this place was created by something but it does not prove the existence of the christian God from the Bible. It simply proves we are a part of a much larger, highly advanced well-oiled machine.

This simulated Earth matrix is layers upon infinite layers of microcsoms and macrocosms in the physical 3D plane. The Golden Ratio and Fibonacci sequence is seen all throughout nature in small scales like seashells, pinecones, the human ear and even as ultra small as human DNA itself and extending to much larger scales like The Earth/moon ratio seen in this video. Yes, this place was created by something but it does not prove the existence of the christian God from the Bible. It simply proves we are a part of a much larger, highly advanced well-oiled machine.

𝒦𝑒𝓁𝓁𝓎࿎☽

35,663 次观看 • 2 个月前

Leavitt on MRI: As part of president trump's comprehensive executive physical, advanced imaging was performed because men in his age group benefit from a thorough evaluation of cardiovascular and abdominal health. The purpose of this imaging is preventive. To identify any issues early, confirm overall health, and ensure the president maintains long-term vitality and function. President trump's cardiovascular imaging was perfectly normal. No evidence of arterial narrowing impairing blood flow or abnormalities in the heart or major vessels. The heart chambers are normal in size, the vessel walls appear smooth and healthy. And there are no signs of inflammation or clotting. Overall, his cardiovascular system shows excellent health. His abdominal imaging is also perfectly normal.

Leavitt on MRI: As part of president trump's comprehensive executive physical, advanced imaging was performed because men in his age group benefit from a thorough evaluation of cardiovascular and abdominal health. The purpose of this imaging is preventive. To identify any issues early, confirm overall health, and ensure the president maintains long-term vitality and function. President trump's cardiovascular imaging was perfectly normal. No evidence of arterial narrowing impairing blood flow or abnormalities in the heart or major vessels. The heart chambers are normal in size, the vessel walls appear smooth and healthy. And there are no signs of inflammation or clotting. Overall, his cardiovascular system shows excellent health. His abdominal imaging is also perfectly normal.

Acyn

509,285 次观看 • 7 个月前

💥Interesting video about blood types. All for a purpose. Akashic Records The Akashic Records are a concept found in various spiritual and esoteric traditions, often described as a universal library or archive of all events, thoughts, and emotions that have ever occurred. It's believed to be a non-physical realm where information about every soul's journey and experiences is stored. Think of it as a cosmic record book of everything that has ever happened, is happening, and will happen. @CaptKylePatriots

💥Interesting video about blood types. All for a purpose. Akashic Records The Akashic Records are a concept found in various spiritual and esoteric traditions, often described as a universal library or archive of all events, thoughts, and emotions that have ever occurred. It's believed to be a non-physical realm where information about every soul's journey and experiences is stored. Think of it as a cosmic record book of everything that has ever happened, is happening, and will happen. @CaptKylePatriots

Capt Kyle

26,425 次观看 • 1 年前

Internationally renowned molecular geneticist Dr Michael Nehls, author of the ‘Indoctrinated Brain’ shocked the world with his claims that the spike protein is being used to shut down the mental immune system of the brain. Now a major South Korean observational study has confirmed a marked increase in psychiatric adverse events amongst the vaccinated. In the 2 million study population they saw an increase in neurosis related disorders such as depression, anxiety, sleep and sexual disorders. But a decrease in psychosis disorders such as bipolar. ‘ Our findings suggested that the relationship between Covid-19 vaccination and mental illness may be underestimated along with the complexity of its impact on mental health.’ But as Dr Nehls points out the powers that be have known this for years and created ‘an efficient bioweapon to target the brain’.

Internationally renowned molecular geneticist Dr Michael Nehls, author of the ‘Indoctrinated Brain’ shocked the world with his claims that the spike protein is being used to shut down the mental immune system of the brain. Now a major South Korean observational study has confirmed a marked increase in psychiatric adverse events amongst the vaccinated. In the 2 million study population they saw an increase in neurosis related disorders such as depression, anxiety, sleep and sexual disorders. But a decrease in psychosis disorders such as bipolar. ‘ Our findings suggested that the relationship between Covid-19 vaccination and mental illness may be underestimated along with the complexity of its impact on mental health.’ But as Dr Nehls points out the powers that be have known this for years and created ‘an efficient bioweapon to target the brain’.

Kat A 🌸

423,615 次观看 • 2 年前

🚨 Ebro and Eddie say Drake’s No. 1 records and Michael Jackson’s No. 1 records shouldn’t be compared without context They say, Drake absolutely deserves credit for breaking the record… but charting in the streaming era is very different from charting in the physical sales era They point out that more than 50% of Drake’s No. 1 records involved collaborations or featured artists, adding another layer to the comparison Ebro says people celebrate the record without discussing how different the eras and the paths to No. 1 actually were “There’s a physical media era and a streaming era.” via Rap Life Review

🚨 Ebro and Eddie say Drake’s No. 1 records and Michael Jackson’s No. 1 records shouldn’t be compared without context They say, Drake absolutely deserves credit for breaking the record… but charting in the streaming era is very different from charting in the physical sales era They point out that more than 50% of Drake’s No. 1 records involved collaborations or featured artists, adding another layer to the comparison Ebro says people celebrate the record without discussing how different the eras and the paths to No. 1 actually were “There’s a physical media era and a streaming era.” via Rap Life Review

CY Chels

267,665 次观看 • 1 个月前

Castor oil in your belly button can soothe your nervous system and support most organs from just rubbing it in your belly button. The naval is a central hub to the whole body as it was your original food source in the womb. Just a small amount works ABC —> Always Be Cleansing

Castor oil in your belly button can soothe your nervous system and support most organs from just rubbing it in your belly button. The naval is a central hub to the whole body as it was your original food source in the womb. Just a small amount works ABC —> Always Be Cleansing

Cleanse Parasites .com 🧹🪱 Herbal Cleanse Co.

176,854 次观看 • 11 个月前

🚨#BREAKING: Officials are urgently searching for 40 Rhesus monkeys that escaped from bio-research lab 📌#Yemassee | #SouthCarolina Currently an urgent search is underway as authorities report that 40 to 43 rhesus monkeys escaped from a research bio-lab facility in the Yemassee area of South Carolina on Wednesday evening. Officials from the Yemassee Police Department confirmed that the monkeys escaped from the Alpha Genesis Primate bio lab Research Center. Traps have been set up in the area, and police are using thermal imaging cameras to help locate the animals. Authorities are advising residents to keep doors and windows closed, avoid approaching the monkeys, and call 911 immediately if they see any of the escaped animals, as this could pose a public health concern.

🚨#BREAKING: Officials are urgently searching for 40 Rhesus monkeys that escaped from bio-research lab 📌#Yemassee | #SouthCarolina Currently an urgent search is underway as authorities report that 40 to 43 rhesus monkeys escaped from a research bio-lab facility in the Yemassee area of South Carolina on Wednesday evening. Officials from the Yemassee Police Department confirmed that the monkeys escaped from the Alpha Genesis Primate bio lab Research Center. Traps have been set up in the area, and police are using thermal imaging cameras to help locate the animals. Authorities are advising residents to keep doors and windows closed, avoid approaching the monkeys, and call 911 immediately if they see any of the escaped animals, as this could pose a public health concern.

R A W S A L E R T S

6,841,052 次观看 • 1 年前

REPORT: New evidence reveals Fauci KNEW all along that COVID came from the Wuhan lab, but he decided to keep that information hidden from President Trump and the public. Emily Kopp at Daily Caller reveals U.S. intelligence knew back in 2019 about a possible Wuhan lab accident — but Fauci’s allies buried that intel and told the public it came from nature instead. Former CDC Director Robert Redfield said Fauci sat through 16 White House meetings in early 2020 and NEVER ONCE brought up the Wuhan lab — even as evidence piled up. As Redfield put it: “My sense is that Fauci had to know all along that the most likely source of the outbreak was the Wuhan laboratory. I was called a conspiracy person. The real conspiracy was the decision to suppress that information from the American public.”

REPORT: New evidence reveals Fauci KNEW all along that COVID came from the Wuhan lab, but he decided to keep that information hidden from President Trump and the public. Emily Kopp at Daily Caller reveals U.S. intelligence knew back in 2019 about a possible Wuhan lab accident — but Fauci’s allies buried that intel and told the public it came from nature instead. Former CDC Director Robert Redfield said Fauci sat through 16 White House meetings in early 2020 and NEVER ONCE brought up the Wuhan lab — even as evidence piled up. As Redfield put it: “My sense is that Fauci had to know all along that the most likely source of the outbreak was the Wuhan laboratory. I was called a conspiracy person. The real conspiracy was the decision to suppress that information from the American public.”

The Vigilant Fox 🦊

46,059 次观看 • 10 个月前

BREAKING: In a Colorado Courtroom, lawyers for the brave Clerk & Recorder of Mesa County revealed to the judge that Dominion voting systems and the Secretary of State plotted & deleted records from the machines after the 2020 election, disguising it as a system update This is exactly what technology experts like Elon Musk and others have been warning election officials about We drove for what felt like an eternity through the Rocky Mountains in a Cybertruck to investigate this case, which is one of the most important in the country. They are trying to make an example out of Tina Peters, and we CAN'T let that happen We talked to Tina Peters🇺🇸 Whistleblower of fallen Navy SEAL and discovered even more SHOCKING facts. Stay tuned!

BREAKING: In a Colorado Courtroom, lawyers for the brave Clerk & Recorder of Mesa County revealed to the judge that Dominion voting systems and the Secretary of State plotted & deleted records from the machines after the 2020 election, disguising it as a system update This is exactly what technology experts like Elon Musk and others have been warning election officials about We drove for what felt like an eternity through the Rocky Mountains in a Cybertruck to investigate this case, which is one of the most important in the country. They are trying to make an example out of Tina Peters, and we CAN'T let that happen We talked to Tina Peters🇺🇸 Whistleblower of fallen Navy SEAL and discovered even more SHOCKING facts. Stay tuned!

George

1,253,227 次观看 • 1 年前

During the B787 startup, the stick shakers in the flight deck kick in as part of the normal stall warning self test. It just checks that the actuators under the control columns are working properly so the system is ready to give pilots that strong physical warning if needed. Basically, the shaker vibrates the yoke to feel like the real aerodynamic buffet you'd get when the plane is approaching a stall... high angle of attack. It’s a clear hands on alert so the crew knows to do something before things get dangerous. One of the important layers in Boeing’s stall protection setup.

During the B787 startup, the stick shakers in the flight deck kick in as part of the normal stall warning self test. It just checks that the actuators under the control columns are working properly so the system is ready to give pilots that strong physical warning if needed. Basically, the shaker vibrates the yoke to feel like the real aerodynamic buffet you'd get when the plane is approaching a stall... high angle of attack. It’s a clear hands on alert so the crew knows to do something before things get dangerous. One of the important layers in Boeing’s stall protection setup.

Fahad Naim

109,811 次观看 • 7 天前

One of the most remarkable speeches by Pope Benedict XVI, delivered at the German Bundestag. “Yet I would like to underline a point that seems to me to be neglected, today as in the past: there is also an ecology of man. Man too has a nature that he must respect and that he cannot manipulate at will. Man is not merely self-creating freedom. Man does not create himself. He is intellect and will, but he is also nature, and his will is rightly ordered if he respects his nature, listens to it and accepts himself for who he is, as one who did not create himself. In this way, and in no other, is true human freedom fulfilled.”—Pope Benedict XVI

One of the most remarkable speeches by Pope Benedict XVI, delivered at the German Bundestag. “Yet I would like to underline a point that seems to me to be neglected, today as in the past: there is also an ecology of man. Man too has a nature that he must respect and that he cannot manipulate at will. Man is not merely self-creating freedom. Man does not create himself. He is intellect and will, but he is also nature, and his will is rightly ordered if he respects his nature, listens to it and accepts himself for who he is, as one who did not create himself. In this way, and in no other, is true human freedom fulfilled.”—Pope Benedict XVI

Coworkeroftruth

79,490 次观看 • 6 个月前