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Those eating plant-based diets average about twice the estimated daily protein requirement. The myth that proteins from plants are incomplete, necessitating protein combining, was debunked decades ago by the scientific community.

22,879 просмотров • 4 месяцев назад •via X (Twitter)

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Proof that Life is Intelligently Designed: Proteins. They do everything in your cells that keeps you alive. These microscopic molecules must have been created. Here is why: Proteins are the building blocks of all the little nano-machines that make up your cells. They do all the major work in your body - from creating energy to recycling waste. Proteins are made from amino acids connected into a specific sequence and then folded into a functional shape. You can think of a protein like a paragraph, and amino acids as the individual letters that spell out the words. Here is where it gets interesting... There are just 20 amino acids used in all of Life. Just 20 amino acids. Responsible for ~200 million unique proteins making up tens of thousands of cell types across Life. And scientists are constantly finding new ones. Scientists categorize proteins into Families. Protein Families are groups of proteins that share amino acid sequence similarities. There are ~22,000 Protein Families. Here's the part that screams they are designed... Protein Families have no evolutionary history. Even evolutionist scientists agree - they are absolutely unique. It's been said that proteins are like stars in a galaxy, and families are like galaxies, with vast empty space between them. Evolution is supposed to build by tweaking things that already exist. But no evolutionary history connects fundamentally distinct protein families. Experiments have been done to intentionally evolve one protein family into another. They fail every time. One protein family cannot be evolved into another. They cannot arise through evolution. But the math really makes it impossible... The odds of evolution finding even a single functional protein family is 1 chance in 10^77 possible amino acid sequences. That's a 1 with 77 zeroes. The odds of evolution finding 22,000 distinct protein families? Roughly 1 chance in 10^1,694,000. You don't need to be a mathematician to understand that this is impossible. Evolution works by random mutations tweaking what's already there. But protein families can't evolve from one another. And the math makes it absolutely absurd to believe. Monkeys banging on keyboards will never type out Shakespeare. And random mutations in sequences of amino acids could never create a single functional protein family. There is only one thing we know of that creates functionally specified sequences: Intelligence. Now here is the final cherry on top: Proteins are built by other proteins, assembled into a complex machine to do a job in cells. The assembly instructions for those proteins and the machines are found in DNA. But DNA requires protein machines for replication & repair. So DNA is required to make Proteins... ...but Proteins are required to make DNA *and* more Proteins. You can't have one without the other. They rely on each other. Which means one couldn't have evolved and then waited for the other. They couldn't do anything without each other. They had to be created at the same time to function together. Life was Divinely Designed. Proteins prove it.

Divinely Designed

18,886 просмотров • 2 месяцев назад

Plant Protein is as Good as Animal Protein for Building Muscle? New Study Breakdown! A new study just dropped demonstrating that a plent blend was as good as whey protein at building muscle over 12 weeks in untrained men undergoing a resistance training program. The headline may surprise some of you, but when I read the full study, I was not surprised at all… why? Because the plant blend was matched to whey in leucine and total EAAs. When you equalize the actual anabolic signals, the gap closes — which is exactly what my PhD thesis showed nearly 20 years ago. Study details (PMID: 41059835) • Randomized, controlled trial in untrained men • Whey vs. plant blend (pea + soy + added leucine) • 12-week supervised resistance-training program • Outcomes: quadriceps cross-sectional area (ultrasound), DEXA, lower-body strength • Result: Both groups improved significantly, with no between-group differences in hypertrophy or strength. This is in line with my PhD research which demonstrated that wheat (a poor protein for stimulating muscle protein synthesis) was as good as whey at stimulating MPS when leucine was added to wheat protein to match the leucine content of whey (PMID: 22818257) Important nuance: The plant blend used in this study is not commercially available, and appears that it was formulated + fortified to match whey’s leucine/EAA profile. That’s why it performed similarly, not because all plant proteins are inherently equivalent to whey for anabolism If your plant protein is low in leucine or EAAs… the results won’t look like this. That said, a plant protein sources can still be as anabolic as animal protein sources if their leucine/EAA content is high enough or if you consume enough protein overall

Layne Norton, PhD

27,356 просмотров • 8 месяцев назад

I do not know who the guy is on the podcast with Raj Shamani, but he is absolutely wrong. There seems to be a section of "health influencers" who fearmonger the public on "dangers of whey protein or protein supplementation." Ammonia production is not a side effect of whey protein metabolism, but is a normal metabolic product of any protein metabolism. Ammonia is natural, generated as a by-product of protein ingestion through the breakdown of amino acids. Of the amino acids, glutamate is the one that has maximal free ammonia generation. In normal healthy persons, excessive ammonia generation is handled by the body and it does not affect brain function. This is done via the "urea cycle" in the liver: In patients with liver disease such as acute liver failure or chronic liver failure, the excess ammonia cannot be cleared out by the weak/failing liver or utilized in the muscles (because of muscle loss in liver patients) and affects brain functioning, leading to a condition called hepatic encephalopathy. This does not happen if you are healthy and taking additional protein. In fact, animal meats are more ammonia generating than plant-based or dairy-based protein and in those chronic liver failure patients with recurrent or persistent ammonia related brain dysfunction, the dietary advise is to limit animal meats and include more or switch to dairy+plant-based protein to keep ammonia generation low. Whey protein and scoops of additional whey protein to target protein requirement is perfectly safe and does not affect brain function or make the person slow like what is discussed in this video. Even advanced cirrhosis patients are supplemented with whey based protein formulations to target additional protein requirements and improve quality of life and immune functions Eg: and I hope we develop a law to deport brain dead misinformation peddling sub-standard "health influencers," like this guy in suit.

TheLiverDoc™

241,731 просмотров • 2 лет назад

What seemed like an intractable problem is now possible: To design proteins with a specified nonlinear mechanical response, capturing complex folding and unfolding mechanisms in singe and few-shot computations. We present ForceGen, an end-to-end algorithm for de novo protein generation based on nonlinear mechanical unfolding responses. Rooted in the physics of protein mechanics, this generative strategy provides a powerful way to design new proteins rapidly, including exquisite and rapid predictions about their dynamical behavior. Proteins, like any other mechanical object, respond to forces in peculiar ways. Think of the different response you'd get from pulling on a steel cable versus pulling on a rubber band, or the difference between honey and glass. Now, we can design proteins with a set of desirable mechanical characteristics, with applications from health to sustainable plastics. The key to solving this problem was to integrate a protein language model with denoising diffusion methods, and using accurate atomistic-level physical simulation data to endow the model a first-principles understanding. ForceGen can solve both forward and inverse tasks: In the forward task, we can predict how stable a protein is, how it will unfold and what the forces involved are, all given just the sequence of amino acids. In the inverse task, we can design new proteins that meet complex nonlinear mechanical signature targets. Read the paper, led by LAMM@MIT postdoc Bo Ni, published in Science Advances: Why do we care about the mechanics of proteins? The mechanics of proteins are critical elements of many living systems - as evidenced in many studies of mechanobiology. Through evolution, nature has presented a set of remarkable protein materials with unique mechanical functions like elastins, silks, keratins or collagens that play crucial roles in biology. However, going beyond natural designs to discover proteins that meet specified mechanical properties remains challenging. So far, the only way to do this was to use existing evolutionary concepts or to manually alter proteins. With our new generative model we can directly design proteins to meet complex nonlinear mechanical property-design objectives. ForceGen leverages deep knowledge on protein sequences from a pretrained protein language model and maps mechanical unfolding responses to create proteins. Via full-atom molecular simulations for direct validation from physical and chemical principles, we demonstrate that the designed proteins are de novo, and fulfill the targeted mechanical properties, including unfolding energy and mechanical strength, and a detailed unfolding force-separation curves. ForceGen offers rapid pathways to explore the enormous mechanobiological protein sequence space unconstrained by biological synthesis, to enable the discovery of new protein materials with superior mechanical properties. B. Ni, D.L. Kaplan, M.J. Buehler, ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a language diffusion model. Sci. Adv. 10, eadl4000 (2024). DOI: 10.1126/sciadv.adl4000 Codes and model weights available Hugging Face: David Kaplan

Markus J. Buehler

47,269 просмотров • 2 лет назад

New Research Reveals, 74% Of Protein Powders Are Contaminated With Heavy Metals & Toxins...Mercury, Arsenic, Lead, Cadmium & BPA. Certified Organic Protein Powders Tested Worse Than Non-Organic Powders. Plant Based Protein Powders Tested Worse Than Whey, Egg & Beef Powders. 👎74% of the 160 protein powders tested, which represented 83% of the market, showed detectable & alarming levels of heavy metals & toxins like BPA. 👎 47% of the protein powders tested exceeded Prop 65 heavy metal limits (organic brand varieties averaged 2x the heavy metals amounts)! 👎 Many plant-based proteins were even WORSE (some plant-based protein powders tested contained up to 3x more toxic heavy metals than whey-based protein powders)! 👎 33% of all protein powders tested exceeded limits for hormone disruptors like BPA (and BPA can be linked to fertility issues, cognitive issues, and more)! (As) Arsenic, (Cd) Cadmium, (Hg) Mercury, (Pb) Lead: As, Cd, Hg, and Pb toxicity cause adverse human health effects, including carcinogenesis, neurotoxicity, nephrotoxicity & reproductive issues. For example, chronic exposure to Cadmium causes renal disease, thyroid disruption & weakened bones. Chronic exposure to Arsenic causes dermal lesions & carcinogenic effects. High doses of ingested Lead compete with calcium in the body, affecting neurotransmitter release & heme iron synthesis, which results in nervous, hematological, reproductive & renal effects. Mercury exposure causes neurological, motor, renal, cardiovascular, immune & reproductive dysfunction. This is why it is imperative to get all or most of our daily protein from single ingredient whole food animal based sources. Eggs, Beef, Pork, Poultry, Lamb, Goat, Venison, Bison & Seafood provide abundant nutrition without heavy metals, toxins or contaminants. With so many protein powder brands compromised, is there even a safe alternative for emergency or occasional use? For now, all you can do is: ✔️ Always request third-party testing results from any brand you wish to use (if they fail to respond, that’s not a good sign). ✔️ Consider whey or egg-based proteins—they were the cleanest in the study. ✔️ Try to maximize protein intake goals/needs by eating clean and organic WHOLE FOODS like 100% grass-fed, grass-finished regenerative farmed beef, 100% wild-caught salmon and other fish, 100% free-range and cage-free chicken, and other clean sources of protein. If you are searching for a 3rd party tested 100% grass fed beef protein powder, let me know in the comments. I have contacted a well respected company & vetted their 3rd party testing in order to recommend one to my coaching clients when they require a clean protein powder. 👇Heavy Metals Found In Protein Powders👇 👇Clean Label Project Heavy Metals Study👇 👇Consumer Reports On Protein Powders👇 Speaker: Dr Raymond Francis Video: Societywellness

Valerie Anne Smith

68,418 просмотров • 1 год назад