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Today we’re previewing NeuralPLexer3 Beta: demonstrating unprecedented accuracy and speed in predicting protein-drug complexes, with instant and accurate structural insights across the full range of protein classes and drug molecules. Learn more:

Iambic Therapeutics

3,388 subscribers

57,519 次观看 • 1 年前 •via X (Twitter)

教育健康养生科学技术

Anya Rossi• Live Now

Private livecam show

1 条评论

Vladas Oleinikovas, PhD 🇪🇺 的头像

Vladas Oleinikovas, PhD 🇪🇺1 年前

Impressive results on PoseBusters v2 dataset, what time cutoff did you use and are you planning to share the predicted structures for evaluation?

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Many protein complexes that drive key processes in cells are “molecular motors”—assemblies that consume (electro)chemical energy to produce mechanical work. A 2023 #SciencePerspective discusses how insights from biophysical, biochemical, and structural studies are starting to yield an understanding of the mechanism by which these motors extrude loops of DNA to structure genomes. Learn more:

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Consumer Reports analyzed 23 protein powders and shakes — a range of dairy, beef and plant-based protein supplements — and found that more than two-thirds of the products contained more lead in a single serving than what experts say is safe to consume. Jonathan LaPook, M.D looks at the report.

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Protein timing and distribution are important, but not more important than simply eating enough protein. This doesn’t mean timing is irrelevant. Spreading protein relatively evenly across the day is a reasonable strategy for maximizing opportunities to stimulate muscle protein synthesis. But emerging evidence challenges the idea that the body can only “use” 25-30 grams of protein at a time. In one study, researchers compared 25 g vs. 100 g of protein after exercise. The 100-g dose produced a greater and more prolonged increase in muscle protein synthesis, with very little of the additional amino acids being oxidized. The extra protein wasn’t simply “wasted.” Larger protein meals take longer to digest and absorb, extending the period during which amino acids are available to support tissue protein synthesis. Practically, consuming your daily protein across 2-3 larger meals is not inherently inferior simply because individual meals contain far more than 25-30 grams.

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