Video wird geladen...

Video konnte nicht geladen werden

Beim Laden dieses Videos ist ein Problem aufgetreten. Dies könnte an einem vorübergehenden Netzwerkproblem liegen oder das Video ist möglicherweise nicht verfügbar.

Using solely extracellular action potential recordings, researchers provide a noninvasive method for functional imaging of cortical and spinal axons.

eLife - the journal

176,028 subscribers

31,496 Aufrufe • vor 2 Jahren •via X (Twitter)

Anya Rossi• Live Now

Private livecam show

0 Kommentare

Keine Kommentare verfügbar

Kommentare vom Original-Post werden hier angezeigt

Ähnliche Videos

Ever wanted a functional color Jitter system for texture paint mode of Blender? Here is a simple method

Ever wanted a functional color Jitter system for texture paint mode of Blender? Here is a simple method

Omar Faruq Tawsif🍉

171,440 Aufrufe • vor 1 Jahr

VIDEO: A paralysed man has regained the ability to walk for the first time using only his thoughts, thanks to two implants that restored communication between brain and spinal cord. The advance is the result of more than a decade of work by a team of researchers in France and Switzerland

VIDEO: A paralysed man has regained the ability to walk for the first time using only his thoughts, thanks to two implants that restored communication between brain and spinal cord. The advance is the result of more than a decade of work by a team of researchers in France and Switzerland

AFP News Agency

288,560 Aufrufe • vor 3 Jahren

PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution

PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution

Dr. Filippo Cademartiri

11,849 Aufrufe • vor 1 Jahr

you've heard about and maybe seen high speed imaging, as well as x-ray imaging. Allow me to present you this glorious high speed x-ray imaging of a drill bit in action.

you've heard about and maybe seen high speed imaging, as well as x-ray imaging. Allow me to present you this glorious high speed x-ray imaging of a drill bit in action.

outside five sigma

11,367 Aufrufe • vor 6 Monaten

Microglia feet are highly dynamic and can be in contact with dense networks of axons. In this video by our #ElectronMicroscopy team using MICrONS data, a microglia (purple) contacts with an excitatory pyramidal neuron (gold). Slowly the axons under the feet are revealed.

Microglia feet are highly dynamic and can be in contact with dense networks of axons. In this video by our #ElectronMicroscopy team using MICrONS data, a microglia (purple) contacts with an excitatory pyramidal neuron (gold). Slowly the axons under the feet are revealed.

allen institute

14,327 Aufrufe • vor 1 Jahr

Researchers extracted 2048-bit RSA keys using ONLY fan noise recordings. Not theoretical: PROVEN. A few minutes of acoustic data = your encryption keys compromised. The crypto wars just got acoustic. Mind-blowing proof:

Researchers extracted 2048-bit RSA keys using ONLY fan noise recordings. Not theoretical: PROVEN. A few minutes of acoustic data = your encryption keys compromised. The crypto wars just got acoustic. Mind-blowing proof:

Sam Bent

34,404 Aufrufe • vor 1 Jahr

In the future researchers and scientists will wonder why I prized so highly my exclusive largest collection from VHS consumer recordings of inadvertent adverting recordings. I have 100s of 1000s of these 30 second dramas for AI train. But why? Let Marshall explain:

In the future researchers and scientists will wonder why I prized so highly my exclusive largest collection from VHS consumer recordings of inadvertent adverting recordings. I have 100s of 1000s of these 30 second dramas for AI train. But why? Let Marshall explain:

Brian Roemmele

63,673 Aufrufe • vor 6 Monaten

#MicroscopyMonday 🔬 — A 3D reconstruction of a cleared mouse embryo labeled for neurons (magenta) and muscles (cyan). This type of imaging lets researchers can image deep into biological tissue to study neuronal morphology in an intact animal or embryo. Credit: G Carrillo

#MicroscopyMonday 🔬 — A 3D reconstruction of a cleared mouse embryo labeled for neurons (magenta) and muscles (cyan). This type of imaging lets researchers can image deep into biological tissue to study neuronal morphology in an intact animal or embryo. Credit: G Carrillo

Marine Biological Laboratory (MBL)

21,071 Aufrufe • vor 1 Jahr

Our noninvasive cloning technique just made the TIME Best Inventions of 2025. 🎉 Old cloning took skin cells, meaning a piece of a living animal. Now we can clone using a simple blood draw, with no cuts and no biopsies. A gentler way to clone and a win for the animals.

Our noninvasive cloning technique just made the TIME Best Inventions of 2025. 🎉 Old cloning took skin cells, meaning a piece of a living animal. Now we can clone using a simple blood draw, with no cuts and no biopsies. A gentler way to clone and a win for the animals.

Colossal Biosciences®

12,874 Aufrufe • vor 10 Monaten

This first-of-a-kind report combining hydrodynamic testing, multimodality imaging, and histological assessment on explanted failed TAV found that functional stenosis can occur to a similar extent in the absence of leaflet calcification. #JACCINT #TAVR

This first-of-a-kind report combining hydrodynamic testing, multimodality imaging, and histological assessment on explanted failed TAV found that functional stenosis can occur to a similar extent in the absence of leaflet calcification. #JACCINT #TAVR

JACC Journals

43,037 Aufrufe • vor 2 Jahren

"We (Democrats) have to provide a vision, and the vision is of a functional democracy. The vision is of a government that is not corrupt. The vision is of a government that is actually focused on solutions for people."

"We (Democrats) have to provide a vision, and the vision is of a functional democracy. The vision is of a government that is not corrupt. The vision is of a government that is actually focused on solutions for people."

George Conway ⚖️🇺🇸

41,301 Aufrufe • vor 3 Monaten

A farmer in Bolton says she's treating her herd of dairy cows to live jazz performances in a bid to boost milk production. Researchers say a little rhythm and blues can increase yields by up to four per cent. @nityagrajan has gone to see this method in action.

A farmer in Bolton says she's treating her herd of dairy cows to live jazz performances in a bid to boost milk production. Researchers say a little rhythm and blues can increase yields by up to four per cent. @nityagrajan has gone to see this method in action.

Good Morning Britain

12,272 Aufrufe • vor 10 Monaten

1. First Communication in Dreams Researchers at REMspace have reached a groundbreaking milestone by showing that lucid dreams may open new avenues for communication. Using specially designed equipment, 2 individuals were able to induce lucid dreams and successfully exchange a simple message. This research could unlock new dimensions of human potential and interaction.

1. First Communication in Dreams Researchers at REMspace have reached a groundbreaking milestone by showing that lucid dreams may open new avenues for communication. Using specially designed equipment, 2 individuals were able to induce lucid dreams and successfully exchange a simple message. This research could unlock new dimensions of human potential and interaction.

Mario Nawfal

51,438 Aufrufe • vor 1 Jahr

There's a lot of potential for some cool racing/movement games using the seven sliders

There's a lot of potential for some cool racing/movement games using the seven sliders

Niki

168,773 Aufrufe • vor 2 Monaten

Turkish Bayraktar AKINCI UCAV successfully completed a test flight using ASELSAN’s domestically developed MURAD AESA radar. Using GaN-based X-band technology, it enables long-range multi-target tracking (reportedly up to ~200 km+), SAR imaging, GMTI, and potential beyond-visual-range air-to-air engagements.

Turkish Bayraktar AKINCI UCAV successfully completed a test flight using ASELSAN’s domestically developed MURAD AESA radar. Using GaN-based X-band technology, it enables long-range multi-target tracking (reportedly up to ~200 km+), SAR imaging, GMTI, and potential beyond-visual-range air-to-air engagements.

Clash Report

30,307 Aufrufe • vor 6 Monaten

Can you identify 'belly dancer dyskinesia?' Hint: look for undulating or circular abdominal contractions. Nice case by Cho, Hallett and colleagues in Movement Disorders Clinical Practice Key Points: - Spinal cord or basal ganglia lesions. - If spinal cord origin, the movements tend to continue during sleep. - An MRI may be helpful if a structural lesion is present. - Physiological studies can be helpful. My take: This case they present turned out to be a 'functional movement disorder' and the movements disappeared with sleep. There was no exposure to a dopamine blocking medication. There was no history of abdominal surgery. The authors remind us to uncover possible 'suggestibility, entrainability, and distractibility.' Physiologically the BP potential is actually present WITH functional myoclonus. Many propriospinal myoclonus cases have turned out to be functional movement disorders. HUMBLING even for the experts. … #dyskinesia #bellydancer #functionalmovementdisorder

Can you identify 'belly dancer dyskinesia?' Hint: look for undulating or circular abdominal contractions. Nice case by Cho, Hallett and colleagues in Movement Disorders Clinical Practice Key Points: - Spinal cord or basal ganglia lesions. - If spinal cord origin, the movements tend to continue during sleep. - An MRI may be helpful if a structural lesion is present. - Physiological studies can be helpful. My take: This case they present turned out to be a 'functional movement disorder' and the movements disappeared with sleep. There was no exposure to a dopamine blocking medication. There was no history of abdominal surgery. The authors remind us to uncover possible 'suggestibility, entrainability, and distractibility.' Physiologically the BP potential is actually present WITH functional myoclonus. Many propriospinal myoclonus cases have turned out to be functional movement disorders. HUMBLING even for the experts. … #dyskinesia #bellydancer #functionalmovementdisorder

Michael Okun

12,686 Aufrufe • vor 1 Jahr

Hong Kong researchers say they are developing a more affordable and less invasive method to confirm cancer, with the aim of having fewer patients undergo painful biopsies.

Hong Kong researchers say they are developing a more affordable and less invasive method to confirm cancer, with the aim of having fewer patients undergo painful biopsies.

South China Morning Post

12,520 Aufrufe • vor 1 Monat

Meet the Institute for the Study of War researchers who say the Ukraine war has entered a new phase to Ukraine’s advantage and that now is the time for its allies to provide crucial help.

Meet the Institute for the Study of War researchers who say the Ukraine war has entered a new phase to Ukraine’s advantage and that now is the time for its allies to provide crucial help.

Jim Sciutto

106,329 Aufrufe • vor 3 Monaten