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Why some screenings should start sooner than guidelines | Peter Attia This clip is from episode # 376 of The Drive which was released on 12/15/25. In the full episode, I cover: -Time-restricted eating: minimal effect beyond calorie control, implications for protein intake, and practical considerations for implementing it...

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Peter Attia

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Methylene blue & longevity | Peter Attia, M.D. This clip is from episode # 370 of The Drive which was released on 10/27/25. In the full episode, I cover: -The state of evidence for alleged geroprotective effects of GLP-1 receptor agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements -Risks and benefits associated with low-dose aspirin for cardiovascular disease (CVD) prevention -Evidence regarding optimal protein intake for maximizing muscle mass, and whether follistatin gene therapy might have promise for further increasing muscle gains -How to apply evidence-based reasoning to separate science from speculation in longevity research -More This AMA episode (Ep. # 370) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.
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Methylene blue & longevity | Peter Attia, M.D. This clip is from episode # 370 of The Drive which was released on 10/27/25. In the full episode, I cover: -The state of evidence for alleged geroprotective effects of GLP-1 receptor agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements -Risks and benefits associated with low-dose aspirin for cardiovascular disease (CVD) prevention -Evidence regarding optimal protein intake for maximizing muscle mass, and whether follistatin gene therapy might have promise for further increasing muscle gains -How to apply evidence-based reasoning to separate science from speculation in longevity research -More This AMA episode (Ep. # 370) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

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Could GLP-1s impact aging and cognitive health? | Peter Attia, M.D. This clip is from episode # 370 of The Drive which was released on 10/27/25. In the full episode, I cover: -The state of evidence for alleged geroprotective effects of GLP-1 receptor agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements -Risks and benefits associated with low-dose aspirin for cardiovascular disease (CVD) prevention -Evidence regarding optimal protein intake for maximizing muscle mass, and whether follistatin gene therapy might have promise for further increasing muscle gains -How to apply evidence-based reasoning to separate science from speculation in longevity research -More This AMA episode (Ep. # 370) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.
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Could GLP-1s impact aging and cognitive health? | Peter Attia, M.D. This clip is from episode # 370 of The Drive which was released on 10/27/25. In the full episode, I cover: -The state of evidence for alleged geroprotective effects of GLP-1 receptor agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements -Risks and benefits associated with low-dose aspirin for cardiovascular disease (CVD) prevention -Evidence regarding optimal protein intake for maximizing muscle mass, and whether follistatin gene therapy might have promise for further increasing muscle gains -How to apply evidence-based reasoning to separate science from speculation in longevity research -More This AMA episode (Ep. # 370) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

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5 core principles behind every successful diet | Peter Attia, M.D. This trailer is from “Ask Me Anything” episode # 75 (Ep. # 364) of The Drive which was released on 9/15/25. In the full episode, I cover: -Why diet debates are so polarizing and confusing—and a clear framework to cut through the noise -The real strengths and hidden pitfalls of ketogenic, carnivore, vegan, and Mediterranean diets -How to know if your diet is actually working with lab tests, body scans, and glucose monitoring -Why flexibility and adherence matter more than chasing the “perfect” diet -More This AMA episode (Ep. # 364) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

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Natural sugar vs. refined sugar | Peter Attia This clip is from “Ask Me Anything” episode # 74 (Ep. # 361) of The Drive which was released on 8/18/25 In the full episode, I cover: -Why sugar drives appetite and fat gain: the combined effect of low satiety, insulin spikes, and reward-system hijacking -How sugar substitutes like allulose, stevia, and erythritol stack up for weight control, glycemic impact, and gut health -The metabolic advantages of timing your sugar intake—and how Peter advises patients to do it -Are artificial sweeteners dangerous? A deep dive into cancer risk, cardiovascular health, and what the data really says -More This AMA episode (Ep. # 361) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

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How Much Protein Should You Really Eat Daily? | David Allison, Ph.D. This clip is from episode # 368 of The Drive which was released today (10/13/25). In the full episode, we cover: -Why the protein RDA may be inadequate for most people and how to think about optimal intake -What current evidence shows about muscle protein synthesis and high-protein diets -The limitations and biases of nutrition research, including economic and methodological constraints -How processed and ultra-processed foods fit into the broader discussion of obesity and public health -More Watch or listen (Ep. # 368) to the full episode on my website or your favorite podcast player.

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Can fiber help prevent colon cancer? | Peter Attia, M.D. This clip is from “Ask Me Anything” episode # 77 (Ep. # 372) of The Drive which was released on 11/10/25. In the full episode, I cover: -The true effect sizes for fiber on weight loss, glycemic control, and LDL cholesterol, and how these compare to other interventions. -Whether processed forms of fiber, including fiber supplements, produce the same physiological effects as whole-food sources. -The evidence and uncertainty surrounding fiber’s role in colorectal cancer prevention. -How to combine and time different fiber types to maximize the benefits while minimizing side effects. -Much more. This AMA episode (Ep. # 372) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

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Is Moderate Drinking Healthy? | Peter Attia, M.D. This clip is from “Ask Me Anything” episode # 73 (Ep. # 356) of The Drive which was released on 7/14/25. In the full episode, we discuss: -Additional lifestyle factors that influence dementia risk: smoking, head trauma, alcohol, and sleep -Supplements for brain health: which ones matter and when they’re worth considering -Effective strategies for VO₂ max training: short vs. long intervals -Debunking the “fast vs. slow metabolism” myth: why energy balance and protein matter most for fat loss -More This AMA episode (Ep. # 356) is available exclusively for premium members. Become a member now at to watch or listen on my website or your favorite podcast player.

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Do Fast Metabolisms Exist? | Peter Attia, M.D. This clip is from “Ask Me Anything” episode # 73 (Ep. # 356) of The Drive which was released on 7/14/25. In the full episode, we discuss: -Additional lifestyle factors that influence dementia risk: smoking, head trauma, alcohol, and sleep -Supplements for brain health: which ones matter and when they’re worth considering -Effective strategies for VO₂ max training: short vs. long intervals -Debunking the “fast vs. slow metabolism” myth: why energy balance and protein matter most for fat loss -More This AMA episode (Ep. # 356) is available exclusively for premium members. Become a member now at to watch or listen on my website or your favorite podcast player.

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Women & Fitness After 50: Balancing Zone 2 and Lifting | Peter Attia, M.D. This clip is from “Ask Me Anything” episode # 73 (Ep. # 356) of The Drive which was released on 7/14/25. In the full episode, we discuss: -Additional lifestyle factors that influence dementia risk: smoking, head trauma, alcohol, and sleep -Supplements for brain health: which ones matter and when they’re worth considering -Effective strategies for VO₂ max training: short vs. long intervals -Debunking the “fast vs. slow metabolism” myth: why energy balance and protein matter most for fat loss -More This AMA episode (Ep. # 356) is available exclusively for premium members. Become a member now at to watch or listen on my website or your favorite podcast player.

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The VO₂ max you need to stay sexually active | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

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How scheduling sex can rekindle desire | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

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Do hormones shape female attraction? | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

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How androgen receptors impact testosterone effect | Carole Hooven, Ph.D. (Carole Hooven ) This clip is from episode # 374 of The Drive which was released on 12/1/25. In the full episode, we cover: -A stark contrast of male social bonding compared to females, and evolutionary parallels in chimpanzees -Why females evolved different behavioral strategies: nurturing, risk aversion, and the cultural norms that override biology -Why males commit disproportionately more violent crime, and how cultural and environmental forces shape aggression -How evolution, health, lifestyle, and androgen receptor biology shape modern testosterone replacement therapy (TRT) Watch or listen (Ep. # 374) to the full episode on my website or your favorite podcast player.

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How Women Can Balance Strength and Cardio With Limited Time | Abbie Smith-Ryan, Ph.D. (Abbie Smith-Ryan PhD) This clip is from episode # 378 of The Drive which was released on 1/5/26. In the full episode, we cover: -The benefits of creatine supplementation and importance of protein intake across the menstrual cycle -How pregnancy and the postpartum period affect body composition -The biggest open questions about women’s health: combining menopause hormone therapy with exercise, GLP-1 drugs, minimizing injury risk, and more -How the training response differs between men and women, and the importance of type IIa muscle fibers Listen (Ep. # 378) to the full episode on my website ( or your favorite podcast player.

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Why to-do lists work | Charles Duhigg, M.B.A. (Charles Duhigg) This clip is from episode # 360 of The Drive which was released on 8/11/25. In the full episode, we cover: -How cue-routine-reward loops drive nearly half of daily behaviors -Why positive reinforcement beats punishment for lasting habit change -The role of willpower as a finite resource and how to protect it with context -Why identity and purpose are stronger drivers than discipline -The potential for AI to power habit change through motivation and accountability -More Watch or listen (Ep. # 360) to the full episode on my website ( or your favorite podcast player.

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"Normal" Lab Values Don't Necessarily Mean Optimal | Eric Verdin, M.D. This clip is from episode # 359 of The Drive which was released on 8/3/25. In the full episode, we cover: -Why immune dysfunction may be the “fifth horseman” of aging -Thymic shrinkage, chronic inflammation & vaccine failure with age -How metabolism, oxidative stress, and NAD decline shape the aging process -Practical longevity tools: zone 2 cardio, ketogenic diets, GLP-1s, and rapamycin -The promise and limitations of biological aging clocks -More Watch or listen (Ep. # 359) to the full episode on my website ( or your favorite podcast player.

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