
Andrew Koutnik, Ph.D.
@AKoutnik • 8,581 subscribers
🔬Scientist of Metabolic Health & Human Performance 🏆Elite Performance Consultant & Diabetes Management Coach 🎙️Co-Host of In-Range with Max Domi
Videos

🚨🚴♂️World-class triathlete Lionel Sanders just dropped a bombshell: he’s pre-diabetic. ...true BRAVERY by Lionel, but shocking? Not to us. In 2023, we uncovered "very fit" runners—⬆️VO2Max & ⬇️Body Fat—silently battling the same. ☹️Skeptics laughed. Yet...docs and athletes DM’d us: 'We’re seeing it too.' We ran an analysis on 24-hour glucose data in athletes? Eye-opening at the incidence of level >100mg/dL. 📊🧑🍳We re-ran another analysis on what predicted elevated fasting glucose values in athletes. Shockingly, BMI and fitness level (VO2Max) DID NOT predict basal glucose metabolism/health over time. What did? Daily nutritional patterns. Twitter/X diet discussions can often be hyperbolic, irrational, and frankly unpleasent—but this isn’t noise. It’s evidence. 🌎We know the incidence of pre-diabetes in the US in those >20 y/o is >50%. 80% of people don't know they have pre-diabetes. 🔬We saw it in our studies. Now, elite athletes are publicly disclosing they are seeing the same. So proud of Lionel's bravery as he catalogs the steps he has taken, which has improved his numbers and symptoms. 📈Living with Type-1 Diabetes, I know all too well the symptoms Lionel experienced (fatigue, lethargia, impaired recovery) with elevated glucose (& likely elevated insulin) values. I applaud his bravery, and I am cheering him on as he catalogs his journey to optimal health. 🔗Links to studies are below.
Andrew Koutnik, Ph.D.218,193 Aufrufe • vor 1 Jahr

🚨 BREAKING: For the first time ever, we have official international LOW-CARB HEALTHCARE guidelines for managing Type 1 Diabetes! 🚨 Created by experts & people living with T1D, these guidelines empower healthcare professionals & patients to safely navigate therapeutic carb reduction. 💪 🌟This is a GAME-CHANGER in diabetes care—bridging a critical gap that’s been needed for so long. Let’s spread the word and make history together. 🎥 Watch, share, and tag someone who needs to know! #Type1Diabetes #WorldDiabetesDay #diabetes #DiabetesCare #EmpowerT1D #WDD2024 #metabolichealth 👉 Personal Nutrition Breakthrough T1D Canada Breakthrough T1D American Diabetes Association Diabetes Canada Int. Diabetes Fed. T1D Nutrition Franziska Spritzler Jim Johnson, PhD Ian Lake World Diabetes Day
Andrew Koutnik, Ph.D.75,561 Aufrufe • vor 1 Jahr

🚨New science DEBATE released on HIGH CARB vs KETO: What the new Tim Noakes vs Louise Burke debate actually shows 👇 American Journal of Clinical Nutrition just released it big debate between two of the biggest names in exercise performance asking one loaded question: does a low-carbohydrate diet impair endurance performance? On one side is Louise Burke, one of the most influential sports nutrition researchers in the world. Her argument: yes, low carb can impair performance? She is not saying every athlete must eat high-carb all the time. She is saying performance depends on the event, intensity, environment, training status, sex, and the athlete in front of you. Her biggest physiological point is fuel economy. Near an athlete’s oxidative ceiling (i.e., elite race pace), she argues that carbohydrate produces more usable energy per liter of oxygen than fat. So even if keto adaptation dramatically raises fat oxidation, that does not automatically mean better speed or power. Now I am skeptical of this point, since we have conducted Randomized Controlled Trails in both runners and ironman competitors and showed that athletes at 86% of their VO2max can utilize fat as the predominant fuel while on a very low carb diet and STILL maintain performance. On the other side, Tim Noakes argues: low carb does not necessarily impair performance when athletes are adapted long enough. He points out that many “keto hurts performance” studies are short, often under four weeks, and that several randomized trials lasting four to six weeks report similar performance between high-carb and low-carb groups. He also reframes fatigue. Instead of saying muscle glycogen is always the main limiter, he argues that during prolonged exercise, maintaining blood glucose, the small glucose pool is the most important. In our trial, 10 grams of carbohydrate per hour improved prolonged cycling performance after both diets. Noakes and Burke also did something really special: they developed a CONSENSUS article where they explored key points of AGREEMENT and DISAGREEMENT for future research. This is the coolest part and in my opinion was one of the verty unique aspect of these three studies My take is this: It is not "team high carb" versus "team keto." The weight of the evidence demonstrates that 1) BOTH high and low carb diets can work, and that 2) Carbohydrates during prolonged exercise are valuable...but 3) How this is applied depends on the individual athlete. What's your take?
Andrew Koutnik, Ph.D.15,031 Aufrufe • vor 2 Monaten

I live with an IRREVERSIBLE metabolic disease. I was invited to Washington D.C., to share my 17-year journey with chronic disease and our research to confront America’s chronic disease epidemic. 👨💼📢 Here’s what I shared & 5 policies outlined (see substack) to reverse this epidemic. You may not agree...but I hope you listen. 🧵👇
Andrew Koutnik, Ph.D.46,428 Aufrufe • vor 1 Jahr

🚨🚨10-Year Longitudinal Data On Ketogenic Diet Adverse Events, Bone Mineral Density, Thyroid Function, and Kidney Function: PART 2🚨🚨 NEW DATA OUT TODAY: We (Joseph C. Watso, PhD/ Austin Robinson/ Samuel Klein) just published our PART 2 paper looking at long-term safety and clinical efficacy of ketogenic diet on: ☠️Adverse Events 🦴Bone Mineral Density 🔥Thyroid Function 🫘Kidney Function ...in part 1 we measured advanced cardiovascular health profile in an adult with elevated cardiovascular risk (type 1 diabetes) who followed a ketogenic diet for 10 years and sustained euglycemia (10-Year HbA1c 5.5%). See paper here: PART 2: What did we find? 👉PLEASE WATCH 📷 VIDEO ABSTRACT here ( 180mg/dL). Patient also presented with intact hypoglycemic awareness. 🦴2) Bone Mineral Density: Prior data suggests that short term ketogenic diet may impair markers of bone modeling/remodeling. However, most of these report are short in nature. People with type 1 diabetes are at HIGH risk for lower bone mineral density and fracture (hyperglycemia is risk factor). Here, we observed no negative impact on bone mineral density (using GOLD STANDARD DXA) on a ketogenic diet, despite 10 years of aging with type 1 diabetes. 🔥3) Thyroid Function: Concerns have been raised on how reducing carbohydrates may shift thyroid hormone status and metabolism. However, most of these studies are </=7 days in length. Following a ketogenic diet over a 10-year period, here we observe no negative impact on thyroid function with a 10-year ketogenic diet. 🫘4) Kidney Function: Microvascular disease is a very common complication of type 1 diabetes as hyperglycemia damages the small blood vessel in the kidneys. Adverse structural kidney changes are observed in children with type 1 diabetes as early as 1.5-5 years post diagnosis with eGFR declining over time. We did not observe any deterioration of kidney function in patient with type 1 diabetes over a 10-year period while achieving 10-Year 5.5% HbA1c following a ketogenic diet. 🚨⚠️9) LIMITATIONS: Reminder on limitations. This is an individual case. The importance of this data is in the sheer absence of short or long-term data, hypothesized risk of a KD, and popularity and use of KD which we hope help generate future research questions. 🗒️CONCLUSIONS: In the longest known longitudinal report of a ketogenic diet in a patient with type 1 diabetes, we observed no severe adverse events or negative impacts on bone, kidney, or thyroid health. We in our PART 1 paper, we observed above average cardiovascular disease health. These initial findings should provoke further research into interventions like ketogenic diets to reduce the long-term health risks faced by those living with T1D while closely monitoring both traditional and advanced cardiovascular risk markers. Especially considering that currently available therapies do no reliably allow patients to achieve <7% HbA1c, let alone <5.7% HbA1c. Joseph C. Watso, PhD Cardiovascular & Applied Physiology Lab Studying how health behaviors (e.g., diet, exercise, etc.) affect cardiovascular health and physiology Sansum Diabetes Research Institute Studying how lifestyle, tools, and medicine affect people with diabetes. @fsucehhs FSU Research FSU ISSM AJP-Cell Physiology The diaTribe Foundation Beyond Type 1 Michael Riddell, PhD Nick Norwitz MD PhD Metabolic Mind Dominic D'Agostino Benjamin Bikman
Andrew Koutnik, Ph.D.62,167 Aufrufe • vor 2 Jahren

🚨Please share your lived experience with Type 1 Diabetes & Food (5-10 minutes survey): We have heard from >800 people internationally, but we need your help! Please share! Annalijn I. Conklin, MPH, PhD(cantab) Jim Johnson, PhD @JDRF_Canada @JDRF
Andrew Koutnik, Ph.D.66,420 Aufrufe • vor 2 Jahren

🚨BIG NEWS: $50M Investment to End America's Health Crisis!🚨 🔬I'm Andrew Koutnik, PhD in Nutrition, Metabolism & Diabetes—and a patient living with an irreversible chronic metabolic disease. Thrilled to advise the NEW Coalition for Metabolic Health, LAUNCHED to REVERSE our chronic disease epidemic! Our 4 BOLD objectives: 1⃣Push policy shifts for science-based nutrition guidelines, research, screenings & insurance. 2⃣Fund unbiased research to empower docs & public with real metabolic insights. 3⃣Educate providers, policymakers & YOU on metabolism's power to prevent/reverse disease. 4⃣Incorporate therapeutic nutrition in everyday care via key partnerships. 👉Join the revolution: #MetabolicHealth #ReverseChronicDisease Metabolic Mind Jan Ellison Baszucki Bret Scher, MD Dr. David Ludwig Dominic D'Agostino Benjamin Bikman DoctorTro
Andrew Koutnik, Ph.D.29,638 Aufrufe • vor 10 Monaten
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