Breakthrough
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Videos
Cliff Brangwynne accepted the Breakthrough Prize in Life Sciences for discovering a fundamental mechanism of cellular organization. He reflected on his path into science and the unexpected intersection of materials physics and cell biology that led to his discovery. He closed with a message to young people: “Be yourself, get comfortable being uncomfortable, and stay curious.”
Breakthrough11,517 Aufrufe • vor 5 Tagen
Albert Maguire received the 2026 Breakthrough Prize in Life Sciences for developing a therapy for inherited retinal degeneration that became the first FDA-approved gene therapy for a genetic disease. Maguire recalled that the project began nearly four decades ago during conversations with his now wife (and co-awardee) Jean Bennett. What started as a simple idea eventually led into a breakthrough treatment that has transformed the lives of patients around the world.
Breakthrough18,747 Aufrufe • vor 29 Tagen
Ewin Tang, 2025 Maryam Mirzakhani New Frontiers Prize laureate, speaks about mathematics as an artistic practice that can be challenging and, at times, unrewarding. She reflects on the collaborative nature of the work, describing moments of intense idea-sharing and how, in those moments, mathematics can feel like connecting with something greater.
Breakthrough62,791 Aufrufe • vor 5 Monaten
Congratulations to the Muon g-2 Collaboration CERN Brookhaven Lab Fermilab, winners of the 2026 Breakthrough Prize in Fundamental Physics, for multi-decade, groundbreaking contributions to the measurement of the muon’s anomalous magnetic moment, pushing the boundaries of experimental precision and igniting a new era in the quest for physics beyond the Standard Model.
Breakthrough48,675 Aufrufe • vor 4 Monaten
The man who climbed Taipei 101, Alex Honnold, and Academy Award winner Anne Hathaway highlight the spirit of curiosity that drives scientific discovery. Reflecting on breakthroughs in gene editing, they honored the researchers and physicians behind life-changing therapies, including Kiran Musunuru, Rebecca Ahrens-Nicklas, Peter Marks, and 2025 Breakthrough Prize in Life Sciences laureate David Liu—whose work led to the treatment for baby KJ, also present at the event. Watch the 2026 Breakthrough Prize Ceremony premiere on Sunday, April 26 at 3 PM streaming on this platform.
Breakthrough42,333 Aufrufe • vor 4 Monaten
Juan Maldacena, Breakthrough Prize in Fundamental Physics laureate, spoke about the importance of recognizing scientists who dedicate their lives to extremely challenging work. He added that science is interesting and worth pursuing and that it offers a fulfilling and exciting career.
Breakthrough14,816 Aufrufe • vor 1 Monat
Congratulations to Thomas Gasser, Ellen Sidransky and Andrew Singleton, who win the 2024 Breakthrough Prize in Life Sciences for discovering key genetic risk factors for Parkinson's disease. NIHAging NIH National Human Genome Research Institute @DZNE_en Universität Tübingen
Breakthrough126,509 Aufrufe • vor 2 Jahren
Congratulations to Jean Bennett, Katherine A. High and Albert Maguire, winners of the 2026 Breakthrough Prize in Life Sciences, for developing a therapy for inherited retinal degeneration that became the first FDA-approved gene therapy for a genetic disease. Penn Children's Hospital Rockefeller University
Breakthrough22,412 Aufrufe • vor 4 Monaten
Congratulations to Stuart Orkin and Swee Lay Thein, winners of the 2026 Breakthrough Prize in Life Sciences, for elucidating the mechanism driving the switch from fetal to adult hemoglobin and validating it as a therapeutic target for sickle-cell disease and beta-thalassemia. Boston Children's NIH
Breakthrough14,721 Aufrufe • vor 4 Monaten
Congratulations to David Gross, winner of the 2026 Special Breakthrough Prize in Fundamental Physics, for a lifetime of groundbreaking contributions to theoretical physics, from the strong force to string theory, and for tireless advocacy for basic science worldwide. UC Santa Barbara Kavli Institute for Theoretical Physics
Breakthrough10,264 Aufrufe • vor 4 Monaten
At Breakthrough Discuss 2025, Betül Kaçar (UW–Madison & NASA ) explored “Ancient Biological Signatures,” revealing how resurrecting Precambrian enzymes in living cells reveals Earth’s early biosignatures. Her innovative fusion of synthetic biology and ancestral reconstruction advances our understanding of life’s origins and promises new tools for detecting life beyond Earth. Watch talk here:
Breakthrough11,439 Aufrufe • vor 1 Jahr
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