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eLife - the journal

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Shorts

This 'important' Tools and Resources paper establishes a robust live-imaging toolkit to characterize excitatory and inhibitory synaptic dynamics during neuronal development. The methodology and quantitative data are 'convincing' and well validated.

This 'important' Tools and Resources paper establishes a robust live-imaging toolkit to characterize excitatory and inhibitory synaptic dynamics during neuronal development. The methodology and quantitative data are 'convincing' and well validated.

20,809 просмотров

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.

192,289 просмотров

A new transparent killifish line called klara, generated using #CRISPR/Cas9, can significantly simplify explorations of development, senescence, ageing and regeneration.

A new transparent killifish line called klara, generated using #CRISPR/Cas9, can significantly simplify explorations of development, senescence, ageing and regeneration.

101,874 просмотров

Evidence of artefactual calcium microwaves during calcium imaging of neurons in the hippocampus.

Evidence of artefactual calcium microwaves during calcium imaging of neurons in the hippocampus.

59,673 просмотров

Proteins that allow water to move in and out of cells help shape the development of new blood vessels.

Proteins that allow water to move in and out of cells help shape the development of new blood vessels.

47,061 просмотров

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

83,264 просмотров

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.

86,706 просмотров

Researchers present a platform for cardiac tissue cultivation with 3D ring-shaped cardiac tissues generated from human stem cell-derived cardiomyocytes.

Researchers present a platform for cardiac tissue cultivation with 3D ring-shaped cardiac tissues generated from human stem cell-derived cardiomyocytes.

51,700 просмотров

The path we take while walking on rugged terrain can be mathematically predicted. 🔗

The path we take while walking on rugged terrain can be mathematically predicted. 🔗

38,326 просмотров

Researchers have developed Opto-RhoGEFs, an optimised optogenetic toolbox to reversibly control Rho GTPase activity, advancing the ability to manipulate the barrier between endothelial cells.

Researchers have developed Opto-RhoGEFs, an optimised optogenetic toolbox to reversibly control Rho GTPase activity, advancing the ability to manipulate the barrier between endothelial cells.

48,796 просмотров

An imaging system with an ultra-wide field of view allows scientists to track millions of cells at once in large 3D tissues and embryos.

An imaging system with an ultra-wide field of view allows scientists to track millions of cells at once in large 3D tissues and embryos.

26,506 просмотров

Plant roots can rapidly change the acidity of their cell walls and the root-soil interface to efficiently navigate in the soil environment.

Plant roots can rapidly change the acidity of their cell walls and the root-soil interface to efficiently navigate in the soil environment.

41,099 просмотров

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

35,263 просмотров

Controlling the forces needed to move around is pretty complicated for soft-bodied organisms. Researchers have implemented a new technique for measuring these crawling forces with nanonewton precision in fruit fly larvae.

Controlling the forces needed to move around is pretty complicated for soft-bodied organisms. Researchers have implemented a new technique for measuring these crawling forces with nanonewton precision in fruit fly larvae.

27,923 просмотров

Fibronectin, a key component of the vessel wall, triggers smooth muscle cells to release collagen-rich extracellular vesicles that guide their movement during vessel repair and atherosclerosis.

Fibronectin, a key component of the vessel wall, triggers smooth muscle cells to release collagen-rich extracellular vesicles that guide their movement during vessel repair and atherosclerosis.

13,934 просмотров

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

27,522 просмотров

Generating active T1 transitions through mechanochemical feedback.

Generating active T1 transitions through mechanochemical feedback.

26,108 просмотров

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For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron.

For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron.

eLife - the journal

107,274 просмотров • 2 лет назад

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.

eLife - the journal

103,212 просмотров • 3 лет назад

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

eLife - the journal

83,264 просмотров • 3 лет назад

When a fish beats its tail, it produces vortices in the water that other fish could take advantage of to save energy while swimming.

When a fish beats its tail, it produces vortices in the water that other fish could take advantage of to save energy while swimming.

eLife - the journal

74,217 просмотров • 3 лет назад

Can you infer cause and effect between genes without disturbing the cell? 🧬 This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.

Can you infer cause and effect between genes without disturbing the cell? 🧬 This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.

eLife - the journal

20,000 просмотров • 8 месяцев назад

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

eLife - the journal

38,026 просмотров • 2 лет назад

A novel method for imaging glutamate receptors in situ via #CryoET.

A novel method for imaging glutamate receptors in situ via #CryoET.

eLife - the journal

24,707 просмотров • 1 год назад

Using solely extracellular action potential recordings, researchers provide a noninvasive method for functional imaging of cortical and spinal axons.

Using solely extracellular action potential recordings, researchers provide a noninvasive method for functional imaging of cortical and spinal axons.

eLife - the journal

31,496 просмотров • 3 лет назад

This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.

This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.

eLife - the journal

10,485 просмотров • 7 месяцев назад

Structural insights into actin isoforms #CryoEM

Structural insights into actin isoforms #CryoEM

eLife - the journal

30,434 просмотров • 3 лет назад

“This fundamental work provides a creative and thoughtful analysis of rodent foraging behavior” Mice can take shortcuts to find food, demonstrating their ability to make a mental map of their surroundings.

“This fundamental work provides a creative and thoughtful analysis of rodent foraging behavior” Mice can take shortcuts to find food, demonstrating their ability to make a mental map of their surroundings.

eLife - the journal

18,733 просмотров • 1 год назад

The components of a synapse revealed by expansion microscopy of a single synaptic contact.

The components of a synapse revealed by expansion microscopy of a single synaptic contact.

eLife - the journal

16,788 просмотров • 2 лет назад

Retinal motion statistics during natural locomotion.

Retinal motion statistics during natural locomotion.

eLife - the journal

22,638 просмотров • 3 лет назад

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio

eLife - the journal

11,666 просмотров • 1 год назад

What makes one member of the species behave differently from another? It's a core problem in behavioural #neuroscience. This valuable study seeks an answer for the specific case of the fruit fly expressing preferences for one odour over another.

What makes one member of the species behave differently from another? It's a core problem in behavioural #neuroscience. This valuable study seeks an answer for the specific case of the fruit fly expressing preferences for one odour over another.

eLife - the journal

10,071 просмотров • 1 год назад

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