An opioid with a literal, light-sensitive 'on/off switch' to... avoid fatal side effects, that works in vivo? Look no further - Azomorphine-3 (AM3)! The most exciting study I've been part of, thus far. With Seva Katritch Dirk H. Trauner and Josh Levitz lab.show more

I've been on 2XKO since 2020 and can't believe... it's finally out (well, sorta hah). It's been an exciting and challenging journey, for sure. I think now it's a good time to share some effects and concepts I made. Let's start with Yasuo :) Waaay more stuff in the thread>show more

ESPN shares an interview with a UNC student going... into commercial, with Clemson leading 28-3. "TCU was... I went to that game. And that was, that was one of the saddest feelings I've had in University so far. I've failed midterms before, so that's saying something." 🏈💀 #CFBshow more

"I've been around Knicks fans my whole life. They're... such an amazing fan base. They care so much, and they've had their hearts broken so much. They've seen a lot of bad basketball. To see the joy that it brought the city and the fan base, to me that was the most special part." - Mike Breen on SNY with Steve Gelbs on the Knicks' title runshow more

AI is the craziest thing I kicked off a... bunch of agents before leaving to the gym, i had them work on this game idea I've been toying around with. I get back home and I've completely forgotten about it and I hear a bunch of explosions going off from my office. I look at my PC and find a bunch of tanks in that the agent generated battling each other and lagging like crazy🤣show more

I'm thrilled to share that I've joined UI8 as... a Principal Designer. I've always admired Dash and the team's design principles, work ethics, attention to detail, and it's especially exciting because I've been a long-time user of UI8's products since the very beginning of my career in 2014. Probably always sensed that our work principles match in many aspects. It still feels surreal to join this incredible team with a mission to help building the future of asset marketplaces for designers (and much more). Can't wait to share everything we've been working on with the team! Animation made using Unicorn Studio + Framer. →show more

Nano is a depth-aware atmospheric haze plugin that uses... ML depth estimation to add physically accurate fog and light scattering to your footage. Works *best* on log footage with visible light sources - it analyzes scene highlights then creates airlight (atmospheric scatter) and halation (light bloom) that responds to actual depth in the scene. Pretty clever approach to getting that cinematic haze look without having to pump a fog machine on set. Makes the OG Trapcode Shine look extremely dated (basically 2D light streaks masked by luminance values), and is yet way more controllable than the current crop of generative AI video-to-video tools.show more

LIVE FROM THE ROYAL ALBERT HALL, THE ALBUM, OUT... NOW 🌹I am so proud of this album and I'm so happy I get to share it with you in this way. A real dream come true. I've been ticking a lot of them off this year that it doesn't even feel real sometimes! But we're here and it's happening and you can watch the evening with me this Sunday on ITV and 15th December on CBS for an extra look behind the scenes !!! Royal Albert Hall Elton Johnshow more

Okay... this is actually insane. OpenCodex feels like the... open-source breakthrough I've been waiting for. The best part : You can plug multiple providers into the same OpenAI Codex harness and switch between models depending on the task. Running low on tokens? No problem. Use another provider. OpenRouter free model today? Plug it in. This completely changes how I think about AI coding workflows. And yes... it even works on mobile. OpenCodex might be one of the most useful open-source AI projects I've seen this year. OpenAI built an incredible harness. The open-source community just made it universal.show more

There's been an unfortunate incident in LA with a... Uhaul plowing into a crowd of anti-Khameini protestors This man should never have been able to get near the crowd with a uhaul but some info about the situation seem to be - signage on the truck is anti both the shah and the current ayatollah. is this his actual position or is this camouflage to have gotten into the protest to perpetrate an attack? "no Shah, No regime, No Mullah" Mullah is a religious leader so possibly referring to the current leader and not a king like Pahlavi Timeline appears to be - anti-Khameini protestors try to rip signs off his vehicle and are bashing on the windows and eventually his passenger side window is broken - guy in uhaul then stutterstops forward into the crowd, eventually accelerating further, then stuttering again, then full stopping down the road - there is a man surfing on top of the uhaul in the 3rd video, below I have posted another video showing the man on top of the uhaul trying to take the posters off the side, so he is likely part of the anti-Khameini protestors - uhaul driver is taken into custody by police is this a case of police not having the street sufficiently blocked off and so a guy was able to get a uhaul in here? He should not have been able to drive a uhaul this close to a massive protest crowd There are a lot of people saying this is a terrorist attack, it is possible it could be one but I don't think there's enough information to accurately assert that at this time The chronology of events also shows it is possible that the driver was in fear of his life since protestors were banging on the uhaul, windows, and removing signs+ eventually breaking his window Whatever turns out to be the actual case, it is an unfortunate event and as of right now a seeming silver lining is that no deaths have been reportedshow more

Apple might lose their most loyal users to Vivo.... X300 Ultra is reportedly in development with a focus on professional video creation. If this works out they will eat a chunk of iPhone users especially content creators. Vivo is already doing better in images from last couple of years compared to iPhones and other brands. And now the X300 Ultra is going even harder on video: - Full focal length 4K 120fps 10bit Log across all 3 lenses. - 3D LUT preview while recording in Log. Real time color checking on the go - APV 422 encoding with full ACES workflow support. Direct color grading with cinema cameras Apple's last barrier in mobile imaging is being challenged. And it's not Samsung doing it. Would you switch from iPhone to Vivo for content creation if the video actually delivers? 👇show more

First Path of Exile 2 Review: -Campaign about 35-40... hours -"Dark Souls of ARGPs" another reviewer thought the same thing -No difficulty options -No easy game -Lots of challenging boss fights -Feels so rewarding to beat them -Dark Souls and Elden Ring feeling -Maps are astronomically large (1 h from side to side) -Maps feel a little bit empty in terms of events -Scratched the tiniest surface of the game after 40 hours -Great sense of discovery (mechanics, builds and lore) -Feels like 3 games into one -Almost limitless combinations of builds -Lot easier to respec your skills -50-100 changes was no problem -Outstanding dark theme art direction -Clearly inspired by Diablo 2 -Details on skill effects and boss designs are the best in the industry in the ARPG genre -Blown away by the amount of detail -Most dynamic combat in an ARPG -Switch to controller was a revelation -Feels like a game that was designed for controller first -Plays even better than Diablo 4 with a controller -Potential to be the alltime king of the genre -Some bugs and crashes occurred -Strong believe that the developers will join the annals of greatness alongside Larian Studios and FromSoftware Watch:show more

Star Wars pioneered so many special effects that we... take for granted today. When filming the destruction of Alderaan in Star Wars, the effects team at Industrial Light & Magic used a surprisingly simple practical effect. The planet was a painted sphere suspended in front of a black backdrop. To create the explosion, they rigged the miniature with pyrotechnics and filmed it with high-speed cameras at a faster frame rate so the blast would appear massive and cinematic when slowed down. One interesting detail is that the explosion was partially achieved using gasoline and powdered cement. The cement gave the blast a heavier, planetary look rather than a quick fireball. Because the miniature exploded outward so quickly, the slowed footage helped sell the illusion of an entire planet tearing apart in space. The shot lasts only a few seconds in the final film but became one of the most iconic visual effects moments in cinema history, created years before CGI existed. (Original 1977 footage)show more

❗️President Zelenskyy stated in an interview with Fox News... that the return of Crimea is currently not being discussed and is not on the agenda, although it is Ukrainian territory, important land, and part of Ukraine’s history. He added: “It’s a pity that no. Or not yet. But we’ll see… But the most important thing is not to lose people.”show more

Danielle Smith gets booed at the UCP AGM. Does... Canada work? "I hope people, today, feel a lot more confident that Canada works than they did a couple of days ago." A Canada that works doesn't need Alberta to submit to UN/WEF climate agendas in order to have an economy. A Canada that works doesn't try to replace its citizens with foreigners. A Canada that works doesn't take billions of dollars more from Alberta than we get back. No, Canada and its record debt on top of it, doesn't work.show more

The opening ceremony of the Olympics is not even... hiding the satanic rituals anymore. There is no longer anything hidden in plain sight. These are the demonic dark forces of Satan who want to eclipse the light. You can already see: - Skulls - Motifs of death - Satanic red lighting - Children trapped in tunnels Did anyone notice that the single rider on a pale horse is straight out of the Book of Revelation? "And I looked, and behold a pale horse: and his name that sat on him was Death, and Hell followed with him. And power was given unto them over the fourth part of the earth, to kill with sword, and with hunger, and with death, and with the beasts of the earth." - Revelation 6:8show more

A disturbing interview with double murderer Jaime Osuna, who... was imprisoned for the 2011 murder of Yvette Pena. In 2019, Osuna decapitated and dissected the body of his cellmate, Luis Romero, with a makeshift knife. Using a razor-style blade attached to a handle, Osuna disfigured Romero, cutting out one of his eyes, chopping off one of his fingers and removing part of his ribs and slicing out part of his lung. He ultimately cut off his head. He also posed the body, slicing Romero’s face open on either side of his mouth to resemble an extended smile, according to an autopsy. Guards found Osuna wearing a necklace made of Romero’s body parts.show more

for this video wanted to see how far i... could get with claude code no premiere or after effects allowed this would've taken 15 min using those traditional tools instead i prompted the entire edit and described all effects through natural language it wound up being an incredibly terrible user experience that took me 4 hours and burned through a ton of tokens 😂 shot in ibiza on a $50 camera i got on amazon by my guy Wutshow more

It’s been an outrageous weekend for Vanderbilt Baseball 2026... commit RJ Cope, a 6-foot-8 first baseman and lefty with top-of-scale raw juice from the left side at the plate. The big man is 10-for-16 with a homer, double, four walks to two Ks and three stolen bases. It’s a no-doubt power over hit profile but he’s done an outstanding job of waiting for his pitch and depositing it in gaps like in the video below when he put a defensive two-strike swing on a ball to cash in runs for his team in a critical spot. All of this and Cope is still new to hitting. His potential is off the charts with the bat.show more

Michael Harris II with the diving grab this evening... in Atlanta: 80% catch probability. Why did it look so tough? -5.3 feet below average on the jump, and that's against all OF, not just CF. Tough sun for sure. The broadcast with an excellent theory, they cut to Andruw Jones with "he's probably saying he catches this standing up"! Still a fun catch and exciting finish. Please don't think you're not allowed to love a catch because of what the metrics are. Harris II always tends to catch the ball, the most important thing!show more

One of the most logical explanations of the Watchers... in the Book of Enoch is that they were an elite group of survivors or a breakaway civilization that was not supposed to mix with ordinary survivors, but only to watch over the masses and intervene when necessary. Part of this breakaway civilization fell in love with the "daughters of men," or the daughters of the ordinary survivors. They had children with them and shared their technology. As a result, they were expelled from the elite breakaway civilization. This story appears in many civilizations, from the Bible to the Sumerian Anunnaki, the Greek myth of Prometheus, and Quetzalcoatl in Mesoamerica. This is, by far, the most logical explanation, but being logical does not mean it is the truth. I will share another theory tomorrow.show more