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A single E. coli cell, placed on a dish, will become 70 billion cells in just 12 hours. That’s exponential growth. But a new preprint shows that it's possible to engineer E. coli to grow linearly instead, where only one daughter cell continues dividing and the other stops. First,... some context. In nature, there is a bacterium called Mycobacterium smegmatis (initially discovered in 1884 in ulcers scraped from syphilis patients.) M. smegmatis is weird because it divides asymmetrically. These cells grow only from one end, and all their cell wall biosynthesis machinery is located on that one end. So when the cell divides, one daughter gets this machinery and the other gets nothing. The daughter that gets the machinery can keep dividing immediately, but the other daughter has to remake all that machinery from scratch, so its growth is delayed. E. coli doesn’t grow like this. When it divides, it pinches in the middle and splits everything evenly. Enzymes, metabolites, and proteins get partitioned more or less randomly between the two daughters. For the new preprint, though, researchers engineered E. coli to behave more like M. smegmatis. Here is how they did it: First, they deleted a gene called cyaA, which encodes an enzyme (adenylate cyclase) that makes a molecule called cAMP. cAMP is SUPER IMPORTANT! It is a nutrient sensor that instructs E. coli to switch on genes that help it digest non-glucose carbon sources when glucose is scarce. Without cAMP, E. coli cells growing on alternative carbon sources will starve; they won’t know how to eat the food. Next, they added back a “split” version of the cyaA gene into the cells. In other words, they split the gene in two so that each half of the enzyme is made separately. Cells can only make cAMP, and thus eat non-glucose carbon sources, if these two halves come together. To facilitate that “coming together,” the researchers also fused the split cyaA proteins to sticky proteins that clump together, and to a fluorescent protein (to make it easy to track these molecules in the cell.) So now some interesting things start to happen if you grow E. coli on a growth medium lacking glucose. As the cell grows, its cyaA “halves” start clumping together into a giant ball. Inside the aggregate, the two enzyme halves come together and make cAMP. And when the cell gets big enough and divides, the clump of cyaA RANDOMLY goes to either daughter cell #1 or #2. The daughter that gets the aggregate (called PA+ in this paper) can keep dividing. The daughter that doesn’t (PA–) cannot. It still grows a few times — about four divisions — because it inherits some leftover cAMP from its mother. But after that, the metabolite is diluted away, and the cell stops growing. PA+ cells went through about 23 divisions on average before their aggregate decayed. And the population of cells, as a whole, grew linearly. This paper is cool because there are many applications where exponential growth is too unpredictable and, perhaps, unsafe. If you want to engineer bacteria to deliver drugs, clean up waste, or live in the gut, you don’t want them to double uncontrollably. This paper shows you can make them expand in a controlled, linear way. Alas, mutations could break this whole engineered system. A mutation that restores cyaA, for example, would give cells a new way to make cAMP. Mutations that make the aggregates split between daughters would break the asymmetry, too. But still, I really enjoy proof-of-concept engineering papers like this.show more

Niko McCarty.

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58,028 次观看 • 11 个月前 •via X (Twitter)

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Some microbes carry a protein, called SNIPE, that "chops up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.

Some microbes carry a protein, called SNIPE, that "chops up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.

Niko McCarty.

20,516 次观看 • 5 个月前

There's a bacteriophage that turns bacteria into “liquid crystals.” Specifically, Pseudomonas aeruginosa bacteria make Pf phages, which are rod-shaped, negatively-charged, and measure about 2 micrometers in length (roughly the length of an E. coli cell). These phages leave the cells and enter their surroundings. There, they mix with polymers, also secreted by the cells, to form a crystalline matrix. Surprisingly, this is good for the cells. Although the phages kill some of them, it also makes their biofilms stickier and able to withstand certain antibiotics. These bacteria + phages are prevalent in cystic fibrosis patients; they've formed a sort of symbiotic relationship. The Pf phages are made from thousands of repeating copies of a coat protein, called CoaB, which wraps around a single-stranded, circular DNA genome. These genes are integrated directly on the bacterial chromosome. The bacteria “turn on” these phage genes when placed in a viscous environment with low oxygen levels. This is like a trigger to start forming a biofilm. And the cells make a lot of phages; about 100 billion per milliliter. These liquid crystals form because of a physics principle called “depletion attraction.” If you just mix a bunch of loose or flexible polymers together (such as long carbon chains) they will not form a liquid crystal. But if you mix stiff rods (the phages) with loose polymers at a high enough concentration, the polymers will force the phages close together to create a material that flows like a liquid despite being ordered like a crystal. See the video below. These liquid crystal biofilms are hard to get rid of. The negatively-charged phages block many antibiotics (like aminoglycosides, which are positively-charged) from entering cells. Liquid crystals also retain water, so these biofilms can survive on drier surfaces. I first heard about this from Malmesbury’s excellent newsletter, called “Telescopic Turnip.”

There's a bacteriophage that turns bacteria into “liquid crystals.” Specifically, Pseudomonas aeruginosa bacteria make Pf phages, which are rod-shaped, negatively-charged, and measure about 2 micrometers in length (roughly the length of an E. coli cell). These phages leave the cells and enter their surroundings. There, they mix with polymers, also secreted by the cells, to form a crystalline matrix. Surprisingly, this is good for the cells. Although the phages kill some of them, it also makes their biofilms stickier and able to withstand certain antibiotics. These bacteria + phages are prevalent in cystic fibrosis patients; they've formed a sort of symbiotic relationship. The Pf phages are made from thousands of repeating copies of a coat protein, called CoaB, which wraps around a single-stranded, circular DNA genome. These genes are integrated directly on the bacterial chromosome. The bacteria “turn on” these phage genes when placed in a viscous environment with low oxygen levels. This is like a trigger to start forming a biofilm. And the cells make a lot of phages; about 100 billion per milliliter. These liquid crystals form because of a physics principle called “depletion attraction.” If you just mix a bunch of loose or flexible polymers together (such as long carbon chains) they will not form a liquid crystal. But if you mix stiff rods (the phages) with loose polymers at a high enough concentration, the polymers will force the phages close together to create a material that flows like a liquid despite being ordered like a crystal. See the video below. These liquid crystal biofilms are hard to get rid of. The negatively-charged phages block many antibiotics (like aminoglycosides, which are positively-charged) from entering cells. Liquid crystals also retain water, so these biofilms can survive on drier surfaces. I first heard about this from Malmesbury’s excellent newsletter, called “Telescopic Turnip.”

Niko McCarty.

50,077 次观看 • 7 个月前

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

Divinely Designed

165,896 次观看 • 2 个月前

RULE #6 OF THE PRIMAL DIET Do not eat rock salt. Salt is a rock, and our body cannot process rocks. It has a toxic effect, different from the sodium found as a nutrient in plant or animal foods. Water dissolves rocks, and plants eat rocks, then animals eat plants, and we eat the plants or animals. This for us is food, the minerals are made into nutrients, becoming bio-available. Rock salt is very different from the sodium found in food. According to Aajonus, rock salt is an explosive: "I just want to make sure that you understand salt is dangerous. Salt is an explosive. It is more volatile than nitroglycerin. If you had a pure cake of sodium as big as a football it would take out all of New York City. Just like a 200 ton hydrogen bomb could take out New York City and all of its buildings. So [...] the government, the military gave General Electric 2 billion dollars to make a weapon, out of salt. My father worked on the project for 6 years. It was so untenable they could not make it into a bomb, thank God. Because one and a half degree temperature change a completely isolated sodium could set it off. So they could never temper it, never break it down and ulitize it." — Aajonus Rock salt is a mineral formed from sodium chloride (NaCl). When eating rock salt, during digestion, the sodium is separated from the chloride, so the sodium ion becomes isolated. Isolated sodium is more volatile than nitroglycerin, this is when it becomes an explosive. So during digestion and after, this isolated sodium creates micro-explosions in the blood, destroying other nutrients and killing cells. Aajonus describes in detail what is happening on a cellular level: "When the cell eats normally, there’s a whole network – smorgasbord of nutrients – anywhere from 97 to 117 nutrients…all your vitamins…all your minerals, fats …all the 60 varieties of cholesterol that can be formed …all the different proteins – pyruvates – all 22 amino acids. Everything is in this smorgasbord. When a cell eats, it gets the whole dose and it’s completely nutrified. When salt is eaten, it causes explosions of these nutrients so you may only get 27 or 57 of these nutrients into a cell at once. So every cell becomes deficient any time you use salt with a meal. Not only that, it dehydrates cells." Additionally, when the isolated sodium doesn't explode right away, it can draw other isolated sodium ions to itself, creating sodium clusters, and the magnetism of them can rip off the guts of cells. This makes using rock salt the second worst thing next to cooking in standard diet practices. "One million red blood cells are destroyed by one little grain of salt.", claims Aajonus. Of course, this is not noticeable right away, but long term, it creates significant damage. When part of raw foods, even during digestion, sodium is always bound to other nutrients, they are always connected on a chemical level, it doesn't get isolated and therefore doesn't have this damaging effect. This is why it is key to get sodium from food only. The body detoxifies the unusable, isolated, form of sodium by sweating it out when possible (the body is throwing it off, don't put it back in). Salt also ends up getting stored like most toxins that the body cannot process because they are in excess, which can lead to headaches when it finally gets detoxified. People who have been eating raw and salt-free for many years will often have an immediate reaction when eating salt: Aajonus explains that is what a healthy body does, it has the resources to immediately repeal a toxin instead of "giving up" and storing it somewhere in its tissues, getting more damaged from it. Rock salt also starts tasting too strong, which people report when eating salted cheese after having only eaten raw unsalted cheese for a while. What about salt licks? First of all, herbivores do this, not carnivores. What about sodium needs, and salt cravings? Needs are not the same with raw and cooked foods, but in either case, you get enough sodium from eating raw foods, there is plenty in raw milk, raw celery juice, raw tomatoes, and raw oysters. At least one or two of these foods can easily be added daily to anyone's diet. "Celery contains lots of sodium. The blood is very high like the ocean in sodium, Celery meets that almost perfectly without causing the clumping of the sodium molecules that rock salt does. Salt will destroy red blood cells very quickly, numbs nerves, burns them, ages prematurely inside even without noticing it, until it hits all of a sudden." — Aajonus Note: This is about eating salt. When used in bath, salt doesn't penetrate through the skin, and draws toxins out. It can still be drying and people without moisturized skin could get skin irritation from it.

RULE #6 OF THE PRIMAL DIET Do not eat rock salt. Salt is a rock, and our body cannot process rocks. It has a toxic effect, different from the sodium found as a nutrient in plant or animal foods. Water dissolves rocks, and plants eat rocks, then animals eat plants, and we eat the plants or animals. This for us is food, the minerals are made into nutrients, becoming bio-available. Rock salt is very different from the sodium found in food. According to Aajonus, rock salt is an explosive: "I just want to make sure that you understand salt is dangerous. Salt is an explosive. It is more volatile than nitroglycerin. If you had a pure cake of sodium as big as a football it would take out all of New York City. Just like a 200 ton hydrogen bomb could take out New York City and all of its buildings. So [...] the government, the military gave General Electric 2 billion dollars to make a weapon, out of salt. My father worked on the project for 6 years. It was so untenable they could not make it into a bomb, thank God. Because one and a half degree temperature change a completely isolated sodium could set it off. So they could never temper it, never break it down and ulitize it." — Aajonus Rock salt is a mineral formed from sodium chloride (NaCl). When eating rock salt, during digestion, the sodium is separated from the chloride, so the sodium ion becomes isolated. Isolated sodium is more volatile than nitroglycerin, this is when it becomes an explosive. So during digestion and after, this isolated sodium creates micro-explosions in the blood, destroying other nutrients and killing cells. Aajonus describes in detail what is happening on a cellular level: "When the cell eats normally, there’s a whole network – smorgasbord of nutrients – anywhere from 97 to 117 nutrients…all your vitamins…all your minerals, fats …all the 60 varieties of cholesterol that can be formed …all the different proteins – pyruvates – all 22 amino acids. Everything is in this smorgasbord. When a cell eats, it gets the whole dose and it’s completely nutrified. When salt is eaten, it causes explosions of these nutrients so you may only get 27 or 57 of these nutrients into a cell at once. So every cell becomes deficient any time you use salt with a meal. Not only that, it dehydrates cells." Additionally, when the isolated sodium doesn't explode right away, it can draw other isolated sodium ions to itself, creating sodium clusters, and the magnetism of them can rip off the guts of cells. This makes using rock salt the second worst thing next to cooking in standard diet practices. "One million red blood cells are destroyed by one little grain of salt.", claims Aajonus. Of course, this is not noticeable right away, but long term, it creates significant damage. When part of raw foods, even during digestion, sodium is always bound to other nutrients, they are always connected on a chemical level, it doesn't get isolated and therefore doesn't have this damaging effect. This is why it is key to get sodium from food only. The body detoxifies the unusable, isolated, form of sodium by sweating it out when possible (the body is throwing it off, don't put it back in). Salt also ends up getting stored like most toxins that the body cannot process because they are in excess, which can lead to headaches when it finally gets detoxified. People who have been eating raw and salt-free for many years will often have an immediate reaction when eating salt: Aajonus explains that is what a healthy body does, it has the resources to immediately repeal a toxin instead of "giving up" and storing it somewhere in its tissues, getting more damaged from it. Rock salt also starts tasting too strong, which people report when eating salted cheese after having only eaten raw unsalted cheese for a while. What about salt licks? First of all, herbivores do this, not carnivores. What about sodium needs, and salt cravings? Needs are not the same with raw and cooked foods, but in either case, you get enough sodium from eating raw foods, there is plenty in raw milk, raw celery juice, raw tomatoes, and raw oysters. At least one or two of these foods can easily be added daily to anyone's diet. "Celery contains lots of sodium. The blood is very high like the ocean in sodium, Celery meets that almost perfectly without causing the clumping of the sodium molecules that rock salt does. Salt will destroy red blood cells very quickly, numbs nerves, burns them, ages prematurely inside even without noticing it, until it hits all of a sudden." — Aajonus Note: This is about eating salt. When used in bath, salt doesn't penetrate through the skin, and draws toxins out. It can still be drying and people without moisturized skin could get skin irritation from it.

The Primal Diet by Aajonus Vonderplanitz

18,211 次观看 • 2 年前

There are many of them but one of the most incredible adaptations I've seen is that of an animal that "dies and resurrects," every year. Behold the wood frogs. They're found in North America. In the northern regions where it gets really cold in the winter, these frogs can freeze up to 60-65% of their body. Their heart stops, breathing ceases, and ice forms in body cavities. If this happens to humans or most animals, that's the end. But for wood frogs, they produce glucose and cryoprotectants that prevent cell damage. In spring, they thaw and resume normal functions. Talk about coming back from the dead.

There are many of them but one of the most incredible adaptations I've seen is that of an animal that "dies and resurrects," every year. Behold the wood frogs. They're found in North America. In the northern regions where it gets really cold in the winter, these frogs can freeze up to 60-65% of their body. Their heart stops, breathing ceases, and ice forms in body cavities. If this happens to humans or most animals, that's the end. But for wood frogs, they produce glucose and cryoprotectants that prevent cell damage. In spring, they thaw and resume normal functions. Talk about coming back from the dead.

Arojinle

112,772 次观看 • 3 个月前

Inside every cell, there is a transport system that determines how materials move, signals propagate, and structure is maintained. This video captures that system in motion. The glowing streaks mark the growing ends of microtubules (protein polymers that constantly assemble and disassemble through a process called dynamic instability). Rather than forming permanent tracks, microtubules are rebuilt continuously, allowing cells to reorganize their internal layout in real time. This behavior is essential for life. Cells rely on microtubule dynamics to divide accurately, migrate during development and repair, and maintain long-distance transport in neurons that may span over a meter in length. When this system is altered, the consequences are significant. Certain cancer therapies work by locking microtubules in place, preventing cell division. In contrast, failures in microtubule transport are linked to neurodegenerative conditions (like Alzheimer's) where intracellular delivery breaks down. What appears as abstract motion under a microscope is actually one of the core systems that keeps cells functional, adaptable, and alive. Video Credit: Andy Moore

Inside every cell, there is a transport system that determines how materials move, signals propagate, and structure is maintained. This video captures that system in motion. The glowing streaks mark the growing ends of microtubules (protein polymers that constantly assemble and disassemble through a process called dynamic instability). Rather than forming permanent tracks, microtubules are rebuilt continuously, allowing cells to reorganize their internal layout in real time. This behavior is essential for life. Cells rely on microtubule dynamics to divide accurately, migrate during development and repair, and maintain long-distance transport in neurons that may span over a meter in length. When this system is altered, the consequences are significant. Certain cancer therapies work by locking microtubules in place, preventing cell division. In contrast, failures in microtubule transport are linked to neurodegenerative conditions (like Alzheimer's) where intracellular delivery breaks down. What appears as abstract motion under a microscope is actually one of the core systems that keeps cells functional, adaptable, and alive. Video Credit: Andy Moore

William A. Wallace, Ph.D.

18,469 次观看 • 5 个月前

Apparently, I saw this video online and I decided to share. What this worker is applying is called bitumen, or what many of us know as bituminous coating. Most people think a wall is a solid, impenetrable block, but in reality, it is more like a sponge. Concrete and blocks have microscopic pores that pull water from the earth through a process we call capillary action. This thick black substance is the shield that stops that water from climbing up into the house. It is not about making the wall look good because this part will be buried under the dirt forever. It is about creating a skin that water cannot breathe through. When do you need to do this? The need for this arises because the soil is a very aggressive environment. Water is not your only enemy.. The ground also contains salts and sulfates that want to eat away at the cement. If this moisture finds its way to the steel bars inside the columns, those bars will start to rust. And when steel rusts, it expands, and that expansion is what cracks the concrete from the inside out. This coating is the only thing standing between your foundation and that kind of slow destruction. Thats is why if you see wet patches at the bottom of your walls inside your house, it usually means someone skipped this step or did it poorly during construction. You can apply this anytime you are building parts of a structure that will stay in contact with the ground. It is common in areas where the water table is high or where the soil stays damp for most of the year. This is a one-shot opportunity. Once you backfill the soil, you can never go back to fix it without a lot of expense and a lot of digging. It is about having the foresight to protect the heart of the building while it is still exposed. Please don’t ignore this if you need to. If you ignore it now to save a bit of money, you will be funding the future decay of your own home. I hope this helps.

Apparently, I saw this video online and I decided to share. What this worker is applying is called bitumen, or what many of us know as bituminous coating. Most people think a wall is a solid, impenetrable block, but in reality, it is more like a sponge. Concrete and blocks have microscopic pores that pull water from the earth through a process we call capillary action. This thick black substance is the shield that stops that water from climbing up into the house. It is not about making the wall look good because this part will be buried under the dirt forever. It is about creating a skin that water cannot breathe through. When do you need to do this? The need for this arises because the soil is a very aggressive environment. Water is not your only enemy.. The ground also contains salts and sulfates that want to eat away at the cement. If this moisture finds its way to the steel bars inside the columns, those bars will start to rust. And when steel rusts, it expands, and that expansion is what cracks the concrete from the inside out. This coating is the only thing standing between your foundation and that kind of slow destruction. Thats is why if you see wet patches at the bottom of your walls inside your house, it usually means someone skipped this step or did it poorly during construction. You can apply this anytime you are building parts of a structure that will stay in contact with the ground. It is common in areas where the water table is high or where the soil stays damp for most of the year. This is a one-shot opportunity. Once you backfill the soil, you can never go back to fix it without a lot of expense and a lot of digging. It is about having the foresight to protect the heart of the building while it is still exposed. Please don’t ignore this if you need to. If you ignore it now to save a bit of money, you will be funding the future decay of your own home. I hope this helps.

A.Y.O

75,105 次观看 • 3 个月前

So, my opinion on what the Antarctic (Antarctica) Anomaly is that it's a type of frequency technology. It must be way more powerful than HAARP, as many have claimed it to be, because we would see these anomalies at other HAARP sites, and we don't, not like this. With that said, and I'm very much trying to avoid letting what I want it to be not play a part here, I think it is a technology that is being used either off the coast of Antarctica itself or Bouvet Island. A third possibility is an area just to the northwest of the island that looks odd. It's possible it is a sonar scan from a ship, but why in that remote location? It looks like an antenna set up or rows of something that is out of place. I also believe that the weather events and fires that have taken place in Africa could possibly have been because of this. Each time we saw the anomaly, it was followed by a destructive weather event in Africa. A weird connection to that is we have been told and warned of a very busy 2024 Atlantic hurricane season. This is in part because of the above-average Atlantic ocean temperatures, which is the fuel to Hurricanes. With all this info, it's possible to see how the Anomaly could be a frequency tech that can manipulate or create weather, And or WARM up the Ocean temps to purposely enhance the Hurricane season and Storm growth. Keep in mind that many of our hurricanes and many of the biggest hurricanes have come from the west coast of Africa and form over the Cape Verde islands before heading towards the Caribbean and the United States. This is all of course speculation, and I'm learning many new things every day, so this idea may morph over time as we learn more. In the end, it is very hard to ignore all these findings. #antarctica #anonaly #AntarcticaAnomaly #BouvetIsland

So, my opinion on what the Antarctic (Antarctica) Anomaly is that it's a type of frequency technology. It must be way more powerful than HAARP, as many have claimed it to be, because we would see these anomalies at other HAARP sites, and we don't, not like this. With that said, and I'm very much trying to avoid letting what I want it to be not play a part here, I think it is a technology that is being used either off the coast of Antarctica itself or Bouvet Island. A third possibility is an area just to the northwest of the island that looks odd. It's possible it is a sonar scan from a ship, but why in that remote location? It looks like an antenna set up or rows of something that is out of place. I also believe that the weather events and fires that have taken place in Africa could possibly have been because of this. Each time we saw the anomaly, it was followed by a destructive weather event in Africa. A weird connection to that is we have been told and warned of a very busy 2024 Atlantic hurricane season. This is in part because of the above-average Atlantic ocean temperatures, which is the fuel to Hurricanes. With all this info, it's possible to see how the Anomaly could be a frequency tech that can manipulate or create weather, And or WARM up the Ocean temps to purposely enhance the Hurricane season and Storm growth. Keep in mind that many of our hurricanes and many of the biggest hurricanes have come from the west coast of Africa and form over the Cape Verde islands before heading towards the Caribbean and the United States. This is all of course speculation, and I'm learning many new things every day, so this idea may morph over time as we learn more. In the end, it is very hard to ignore all these findings. #antarctica #anonaly #AntarcticaAnomaly #BouvetIsland

In2ThinAir

442,580 次观看 • 2 年前

🥚 Raw Eggs — They are nature's fast food, and a complete food, with every nutrient you could need. A raw egg digests in only 27 to 37 minutes, which is phenomenal compared to other foods containing protein and fat, like meat and milk. This is because egg is a fully liquid food. The body doesn't need to use any digestive fluids, hydrochloric acid, to break it down, it will absorb within the first 5 inches of the intestine only, from bacterial digestion alone. Of course, if you cook the egg, this doesn't apply anymore. Cooking not only destroys nutrients, especially enzymes and vitamins, which impairs digestion, and generates toxins, like heterocyclic amines from proteins, and cauterizes the minerals, but it coagulates the egg. This not only makes a raw egg the perfect food to get instant energy in a healthful way, but a vital food that can save someone's life. If your digestive system is so compromised you cannot digest other animal protein, like meat, raw eggs will work. Or if you have leaky gut, they digest before they even have to go through the G.I. tract. In general, if you want to give your digestive system a rest, eat raw eggs, you will get back appetite for other foods very soon. In the next post of this thread is a quote of Aajonus' most incredible testimonial on the healing power of raw eggs. They are also the best food to repair. The only thing that Aajonus found that eggs cannot do is help the body reproduce cells quicker. That takes raw meat. So long-term, you cannot replace raw meat with raw eggs, they work complementarily. Don't discard the egg white. Aajonus proved the avidin in raw egg white is not an anti-nutrient. Aajonus ate up to 60 raw eggs a day (one or two dozens on most days) since 1976. He confirmed there was no biotin deficiency whatsoever. The narrow-minded lab experiments do not explain what actually happen and then draw the wrong conclusion. What actually happens is that biotin mixes with avidin to make a compound that cleans the body of biocarbons, which are leftover byproducts from macronutrient digestion that need to be eliminated by the body. This is actually a good thing. Plus, there is an excess of available biotin in raw egg compared to the amount of avidin. It is also recommended by Aajonus to not eat raw egg yolks alone either, as it creates imbalances when on a raw diet (this doesn't apply on a cooked diet). He did the experiments on animals, feeding them raw egg white and raw egg yolk separately, and it made them extremely hungry, they required twice as much food, had huge imbalances emotionally, caused obesity, water retention, all kinds of problems. So, if you go to a restaurant, you can request the egg white to be included in your steak tartare, just like Aajonus did. What about salmonella? Salmonella is already on our skin, in our eyes, our nose, our mouth, recycling dead cells. They are beneficial bacteria, not pathogenic. Of course, this isn't medical advice. Look into Aajonus and more broadly into terrain theory vs germ theory. Don't refrigerate eggs. Only in the USA do people do this. If you wash the egg, you remove the protective membrane around it, then health departments require them to be refrigerated. Just don't wash the eggs. Eggs are a bit of a fragile food, many of its natural bacteria die when in cold temperatures, so it's better to keep them at room temperatures, or they will lose digestibility. You can blend raw eggs, however it will oxidize them, destroying certain nutrients. There are three enzymes in the egg white which prevent certain hormones that help certain diseases progress like cancer. If you as little as whip the raw egg with a work, these enzymes in the egg white oxidize within seconds. Raw eggs are a detoxification food. They are rich in cholesterol. If you drink alcohol, eat plenty of raw eggs (before, during, after), and you will avoid a hangover. The cholesterol in raw eggs is very good at collecting the alcohol and other toxins. They also enable the body to make solvents to break down toxicity like cellulite. Raw eggs can be fermented, and aged in various ways. Century eggs, the real ones (which are around 25 years old), can cost a thousand dollars. They transform in all sorts of shapes, they can look like green boiled eggs, jewelry, eggs that could belong to a dragon, or turn into white, black powder. They can give incredible energy and libido. How to eat: If you eat the raw egg white first, then the yolk right after, the raw egg will digest in 27 minutes, otherwise in 37 minutes. It is easier to do so from the shell by poking a hole on each side and sucking from it. This is "Aajonus-style". From a glass is "Rocky-style". Nowadays also called slonking. Make the egg go through your teeth while you drink it, this makes it easier to mix it with saliva, which allows better digestion. That only works if you eat only one raw egg at a time. If you eat several raw eggs at once, they will digest slower. Not an issue, it is still extremely healthy. Therefore eating raw eggs frequently throughout the day, one at a time, can bring a steady flow of nutrients to your body. Eggs are perfect to eat upon waking up, providing quick energy from fats and providing protein for the body to make glycogen from and feed the nervous system. They are perfect to eat in-between meals. Only take a couple seconds and get you going for hours, and whenever you get tired. Eggs help gain and lose weight. It all depends how you combine them. A raw egg eaten alone can lead to weight loss, except if you eat more than around 22 a day to maintain. Aajonus' weight loss protocol relies on eating a raw egg diet for 1-3 weeks and is very effective. Raw eggs can help remove cellulite, strip down toxic fat (which is fat that was used to store toxins). Eggs eaten with other foods, or several at once, don't have this weight loss effect. They are very good to eat with other foods, such as raw meat (steak tartare). You can easily eat 3 raw eggs with your raw steak. There are many recipes, from raw pastries, to sauces like mayo, milkshakes, ... where you can keep the egg raw and whole.

🥚 Raw Eggs — They are nature's fast food, and a complete food, with every nutrient you could need. A raw egg digests in only 27 to 37 minutes, which is phenomenal compared to other foods containing protein and fat, like meat and milk. This is because egg is a fully liquid food. The body doesn't need to use any digestive fluids, hydrochloric acid, to break it down, it will absorb within the first 5 inches of the intestine only, from bacterial digestion alone. Of course, if you cook the egg, this doesn't apply anymore. Cooking not only destroys nutrients, especially enzymes and vitamins, which impairs digestion, and generates toxins, like heterocyclic amines from proteins, and cauterizes the minerals, but it coagulates the egg. This not only makes a raw egg the perfect food to get instant energy in a healthful way, but a vital food that can save someone's life. If your digestive system is so compromised you cannot digest other animal protein, like meat, raw eggs will work. Or if you have leaky gut, they digest before they even have to go through the G.I. tract. In general, if you want to give your digestive system a rest, eat raw eggs, you will get back appetite for other foods very soon. In the next post of this thread is a quote of Aajonus' most incredible testimonial on the healing power of raw eggs. They are also the best food to repair. The only thing that Aajonus found that eggs cannot do is help the body reproduce cells quicker. That takes raw meat. So long-term, you cannot replace raw meat with raw eggs, they work complementarily. Don't discard the egg white. Aajonus proved the avidin in raw egg white is not an anti-nutrient. Aajonus ate up to 60 raw eggs a day (one or two dozens on most days) since 1976. He confirmed there was no biotin deficiency whatsoever. The narrow-minded lab experiments do not explain what actually happen and then draw the wrong conclusion. What actually happens is that biotin mixes with avidin to make a compound that cleans the body of biocarbons, which are leftover byproducts from macronutrient digestion that need to be eliminated by the body. This is actually a good thing. Plus, there is an excess of available biotin in raw egg compared to the amount of avidin. It is also recommended by Aajonus to not eat raw egg yolks alone either, as it creates imbalances when on a raw diet (this doesn't apply on a cooked diet). He did the experiments on animals, feeding them raw egg white and raw egg yolk separately, and it made them extremely hungry, they required twice as much food, had huge imbalances emotionally, caused obesity, water retention, all kinds of problems. So, if you go to a restaurant, you can request the egg white to be included in your steak tartare, just like Aajonus did. What about salmonella? Salmonella is already on our skin, in our eyes, our nose, our mouth, recycling dead cells. They are beneficial bacteria, not pathogenic. Of course, this isn't medical advice. Look into Aajonus and more broadly into terrain theory vs germ theory. Don't refrigerate eggs. Only in the USA do people do this. If you wash the egg, you remove the protective membrane around it, then health departments require them to be refrigerated. Just don't wash the eggs. Eggs are a bit of a fragile food, many of its natural bacteria die when in cold temperatures, so it's better to keep them at room temperatures, or they will lose digestibility. You can blend raw eggs, however it will oxidize them, destroying certain nutrients. There are three enzymes in the egg white which prevent certain hormones that help certain diseases progress like cancer. If you as little as whip the raw egg with a work, these enzymes in the egg white oxidize within seconds. Raw eggs are a detoxification food. They are rich in cholesterol. If you drink alcohol, eat plenty of raw eggs (before, during, after), and you will avoid a hangover. The cholesterol in raw eggs is very good at collecting the alcohol and other toxins. They also enable the body to make solvents to break down toxicity like cellulite. Raw eggs can be fermented, and aged in various ways. Century eggs, the real ones (which are around 25 years old), can cost a thousand dollars. They transform in all sorts of shapes, they can look like green boiled eggs, jewelry, eggs that could belong to a dragon, or turn into white, black powder. They can give incredible energy and libido. How to eat: If you eat the raw egg white first, then the yolk right after, the raw egg will digest in 27 minutes, otherwise in 37 minutes. It is easier to do so from the shell by poking a hole on each side and sucking from it. This is "Aajonus-style". From a glass is "Rocky-style". Nowadays also called slonking. Make the egg go through your teeth while you drink it, this makes it easier to mix it with saliva, which allows better digestion. That only works if you eat only one raw egg at a time. If you eat several raw eggs at once, they will digest slower. Not an issue, it is still extremely healthy. Therefore eating raw eggs frequently throughout the day, one at a time, can bring a steady flow of nutrients to your body. Eggs are perfect to eat upon waking up, providing quick energy from fats and providing protein for the body to make glycogen from and feed the nervous system. They are perfect to eat in-between meals. Only take a couple seconds and get you going for hours, and whenever you get tired. Eggs help gain and lose weight. It all depends how you combine them. A raw egg eaten alone can lead to weight loss, except if you eat more than around 22 a day to maintain. Aajonus' weight loss protocol relies on eating a raw egg diet for 1-3 weeks and is very effective. Raw eggs can help remove cellulite, strip down toxic fat (which is fat that was used to store toxins). Eggs eaten with other foods, or several at once, don't have this weight loss effect. They are very good to eat with other foods, such as raw meat (steak tartare). You can easily eat 3 raw eggs with your raw steak. There are many recipes, from raw pastries, to sauces like mayo, milkshakes, ... where you can keep the egg raw and whole.

The Primal Diet by Aajonus Vonderplanitz

23,137 次观看 • 1 年前

The Australian government does not deserve our trust, or our respect. Today, Minister Penny Wong sat back in her chair grappling for words, desperately looking for the right lie to tell. It is worse than dishonest - it is an absolute lack of care. Penny Wong came to this country when she was 8 years old. She came to a country that afforded her the ability to become who she is, and she is now doing her part to destroy it. Back in the 70’s, when she came, Australia was a fair-minded place and a great place to be. Yet here she is... Here in Australia. Undermining our country and lying to our faces. Because she can’t tell the truth. Because if she did, it would destroy any semblance of care for Australia tied to her old party’s Labor brand. It would say the quiet part out loud. The truth. The truth that the Albanese government is more interested in the fortunes of the ISIS brides, women who chose to leave this country to go and fight against our people, than those of us that can’t find or afford a place to live here at home. I am tired of being told how to think by people that completely lack morals and couldn’t care less. People that are elected and paid to operate in the national interest but always put their twisted ethics and back pockets ahead of our nation and our people. I don’t know when Labor stopped caring about Australian workers or worse, when they started hating Australia, but they have and they do. The absolute lack of opposition, the lack of authentic choice has pushed us into a place where these absolute traitors to the interests of the people who pay them - goes entirely unchecked. We are careening out of control, unchecked migration, an energy grid that is just about to collapse, no industry to speak of, and no good reason to start or maintain a business in this place. It happened fast, but those of us who pay our taxes and take risks to make Australia a better place, are being undermined and white-anted by our politicians. The people we are forced to trust, and must pretend to respect, because they have the force of law on their side. Not because they are any good at their jobs. Not because they have earned our affection. No. Simply because they are in charge and there is little to nothing that can be done about it. It is becoming apparent that the two party system has outlived its useful life. Too much corruption, too many words too carefully chosen in a pantomime between to political forces that don’t really want to change anything. They just want to have their go, to have their turn to jam their grubby hands into the till. Surely with this major and catastrophic failure by the so-called Honourable Minister Senator Wong, the people will be able to see through the veil and into the absolute and irresponsible lack of care at the heart of this deceitful Labor government. They lie about everything, and they can, because they don’t have an opposition worthy of the title. I am growing more confident by the day that the only solution to our woes is a new political force, a fresh, Australia first force, that will act in the national interest and put all these corrupt and useless used-car salesmen red and blue in the dustbin of history. It can’t come soon enough. Time is short. I just want Australia back.

Matthew Camenzuli

81,553 次观看 • 9 个月前

Ladies and gentlemen, something happened in Tuapse, and we received a video message from the locals. This video is about humanity. This video is about you and me... Why are you, Ukrainians, so brainwashed, angry, and unsympathetic to the grief of the people of Tuapse... And aren’t you ashamed to be like that... But let's be serious. It's 2026, something happened, and instead of Z-festivals, dear Russians were recording videos saying they are just pawns, that they are not guilty, that they sympathize with us, and that they never wanted any of this. And you shouldn't hate them, they are... good. They just want peace, for unicorns to run across the rainbow, and instead of rockets, to launch confetti 🥰 And along with you, madam, there are another 1 million mercenaries fighting in Ukraine, 2.5 million regular scumbags, 2.5 million weaklings, more than 4 million scumbags working in defense industries, 3 million scumbags in the government apparatus. And tens of millions more scumbags to some degree supporting the Kremlin regime. And each. Each of these people deserves liquidation. Because you are a plague, a contagion that must be burned out. Probably if a cancer cell could speak during therapy, it would say something like this: I just exist. I don’t want to kill you. I’m very sorry that you suffer. I wouldn’t want you to die. Can you negotiate with a cancer cell? Can you expect a cancer cell to pity you? Can you expect cancer to retreat on its own? ... No. The so-called Russian Federation is cancer. The enraged, feral Russian society is cancer. Cancer must be burned out, cut out. Every cell must be destroyed. Because cancer will never retreat on its own. If you disagree with the war, if you don’t support your government — leave the country. Until then, each of you is an implicit accomplice and a terrorist. And there’s no whining. Sorry for the long read, it can’t be shorter here.

Ladies and gentlemen, something happened in Tuapse, and we received a video message from the locals. This video is about humanity. This video is about you and me... Why are you, Ukrainians, so brainwashed, angry, and unsympathetic to the grief of the people of Tuapse... And aren’t you ashamed to be like that... But let's be serious. It's 2026, something happened, and instead of Z-festivals, dear Russians were recording videos saying they are just pawns, that they are not guilty, that they sympathize with us, and that they never wanted any of this. And you shouldn't hate them, they are... good. They just want peace, for unicorns to run across the rainbow, and instead of rockets, to launch confetti 🥰 And along with you, madam, there are another 1 million mercenaries fighting in Ukraine, 2.5 million regular scumbags, 2.5 million weaklings, more than 4 million scumbags working in defense industries, 3 million scumbags in the government apparatus. And tens of millions more scumbags to some degree supporting the Kremlin regime. And each. Each of these people deserves liquidation. Because you are a plague, a contagion that must be burned out. Probably if a cancer cell could speak during therapy, it would say something like this: I just exist. I don’t want to kill you. I’m very sorry that you suffer. I wouldn’t want you to die. Can you negotiate with a cancer cell? Can you expect a cancer cell to pity you? Can you expect cancer to retreat on its own? ... No. The so-called Russian Federation is cancer. The enraged, feral Russian society is cancer. Cancer must be burned out, cut out. Every cell must be destroyed. Because cancer will never retreat on its own. If you disagree with the war, if you don’t support your government — leave the country. Until then, each of you is an implicit accomplice and a terrorist. And there’s no whining. Sorry for the long read, it can’t be shorter here.

Exilenova+

31,075 次观看 • 3 个月前

hypergamy is going to hit women like a 50-megaton thermonuclear bomb, and the reason is because these women are hypergamous themselves female hypergamy hit society first due to the natural supply/demand gap between the sexes, and it's certainly caused somewhat of a death spiral of intersexual relations, but the outcome will not be this hypercompetition between men for women, but rather men checking out of the game entirely as the juice stops being worth the squeeze porn is only getting more immersive and sex bots are on the way, and social media exposes men to 10/10 women nonstop; why then would men break their backs for a crumb of attention for mediocre women? even men with genuine value to bring struggle in the current dating market, the fatigue is beginning to set in for women there are two options: a) make the squeeze easier, or b) make the juice more worthwhile a) would require that they lower their standards and expectations, make themselves more accessible, accept a man with less to offer when they know someone better is out there they don't have that in them, so they resort to b) b) means making the juice tastier, it mean tightening up the juice's nasolabial folds and waist-to-hip ratio. it means injecting the juice with hyaluronic acid fillers and, when that isn't enough to get ahead, it means making real changes to the juice's recipe like getting structural surgery there is a very small supply of beautiful people on this planet, but in the age of the internet that small supply is accessible to everyone at all times instead of being a random beautiful stranger you may rarely come across on the street. everyone’s perceptions of what is accessible to them is being distorted, and even if only 1% of people are truly beautiful themselves that is enough for 99% of the subpar masses to feel like they can share. past a certain point of abundance a person cannot comprehend the difference between 10 million people and 1 billion, it’s just a lot. if 1 billion compete for 10 million it still feels like an infinite prize pool. this has corrupted women tremendously, but it is absolutely going to and already beginning to do the same with men as men get more and more immersed in and addicted to cheap hits of sexual dopamine such as porn, social media, online dating (which is a corrupting force for both genders) they will be less and less willing to settle for a girl who is any less than perfect because quite frankly, she probably just won’t be worth it to them anyway there is already a long cultural precedent for women going to extreme measures to looksmaxx for male attention, if men start to become fed up with them and hypergamy increases on both ends the blackpill will explode with women. already women know when they are left on delivered by chad that if they were prettier this wouldn’t be happening, they are beginning to make this observation en masse and it is driving the rise in radfem and “femcel” (i.e. girl who can’t bag chad) ideology. women are realizing that body positivity and self-love was a scam, and that looks are law i’m betting all in on the upcoming female blackpill trend, putting my stock in it. i’d keep an eye out for it because it has already begun and it’s only going to get bigger

Sensitive content

hypergamy is going to hit women like a 50-megaton thermonuclear bomb, and the reason is because these women are hypergamous themselves female hypergamy hit society first due to the natural supply/demand gap between the sexes, and it's certainly caused somewhat of a death spiral of intersexual relations, but the outcome will not be this hypercompetition between men for women, but rather men checking out of the game entirely as the juice stops being worth the squeeze porn is only getting more immersive and sex bots are on the way, and social media exposes men to 10/10 women nonstop; why then would men break their backs for a crumb of attention for mediocre women? even men with genuine value to bring struggle in the current dating market, the fatigue is beginning to set in for women there are two options: a) make the squeeze easier, or b) make the juice more worthwhile a) would require that they lower their standards and expectations, make themselves more accessible, accept a man with less to offer when they know someone better is out there they don't have that in them, so they resort to b) b) means making the juice tastier, it mean tightening up the juice's nasolabial folds and waist-to-hip ratio. it means injecting the juice with hyaluronic acid fillers and, when that isn't enough to get ahead, it means making real changes to the juice's recipe like getting structural surgery there is a very small supply of beautiful people on this planet, but in the age of the internet that small supply is accessible to everyone at all times instead of being a random beautiful stranger you may rarely come across on the street. everyone’s perceptions of what is accessible to them is being distorted, and even if only 1% of people are truly beautiful themselves that is enough for 99% of the subpar masses to feel like they can share. past a certain point of abundance a person cannot comprehend the difference between 10 million people and 1 billion, it’s just a lot. if 1 billion compete for 10 million it still feels like an infinite prize pool. this has corrupted women tremendously, but it is absolutely going to and already beginning to do the same with men as men get more and more immersed in and addicted to cheap hits of sexual dopamine such as porn, social media, online dating (which is a corrupting force for both genders) they will be less and less willing to settle for a girl who is any less than perfect because quite frankly, she probably just won’t be worth it to them anyway there is already a long cultural precedent for women going to extreme measures to looksmaxx for male attention, if men start to become fed up with them and hypergamy increases on both ends the blackpill will explode with women. already women know when they are left on delivered by chad that if they were prettier this wouldn’t be happening, they are beginning to make this observation en masse and it is driving the rise in radfem and “femcel” (i.e. girl who can’t bag chad) ideology. women are realizing that body positivity and self-love was a scam, and that looks are law i’m betting all in on the upcoming female blackpill trend, putting my stock in it. i’d keep an eye out for it because it has already begun and it’s only going to get bigger

𝖒𝖔𝖌𝖌𝖎𝖓𝖌

42,082 次观看 • 23 天前

I understand what Russia wants to achieve with its missile and drone strikes on Ukraine - namely, to destroy peaceful life and drive people into such a psychological state that they are ready to make any concessions just to end it all. However, such strikes have the opposite effect. They remind us that the war is ongoing and that it is not limited to the conflict in the east; they show that at any moment, a missile can take everything away from you. And the only way to prevent this from happening is to donate to the Armed Forces of Ukraine and to hate the Russians even more. I think we can cite examples from World War II, when Hitler's attacks on Great Britain did not break its confidence in the struggle. If the Russians aimed to cause a massive blackout, they failed, wasting dozens of missiles worth tens of millions. But we understand that strikes on oil refineries and other targets must continue! PS: These are small fragments from real life that I filmed. The video may not show it, but the shock wave was strong enough to cause quite intense emotions in me.

I understand what Russia wants to achieve with its missile and drone strikes on Ukraine - namely, to destroy peaceful life and drive people into such a psychological state that they are ready to make any concessions just to end it all. However, such strikes have the opposite effect. They remind us that the war is ongoing and that it is not limited to the conflict in the east; they show that at any moment, a missile can take everything away from you. And the only way to prevent this from happening is to donate to the Armed Forces of Ukraine and to hate the Russians even more. I think we can cite examples from World War II, when Hitler's attacks on Great Britain did not break its confidence in the struggle. If the Russians aimed to cause a massive blackout, they failed, wasting dozens of missiles worth tens of millions. But we understand that strikes on oil refineries and other targets must continue! PS: These are small fragments from real life that I filmed. The video may not show it, but the shock wave was strong enough to cause quite intense emotions in me.

Cloooud |🇺🇦

19,355 次观看 • 9 个月前

"PRICE IS WHAT YOU PAY. VALUE IS WHAT YOU GET." I keep buying $Kekec and I have a strong conviction. Here's Why: While the market is down, and Kekec is declining with it, there are data points that few are considering. Kekec borned in October and since then has been posting a different and original 30-second video every day, which I find extremely funny. For the past couple of months, they have also been posting daily on Instagram, and the attention on Kekec (which doesn't present itself on social media as a memecoin) is growing, moreover, it's increasing exponentially. The number of followers is increasing by about 500-1000 a day. This is largely due to the fact that they are not just focused on the main account but have several others that post reels and redirect to the main one. In short, an excellent strategy to keep growing more and more. Instagram link: Guess What? Not only are the followers increasing, but the team's workload is also growing. In fact, for a little over a month, they have also started pushing on YouTube, and the data here is promising as well. YouTube link: If we want to make a comparison, we can take Pudgy Penguins as an example, which has shown it can reach millions and millions of users without mentioning that they are a WEB3 company that owns an NFT collection. Or, if we want to be more appropriate by comparing one memecoin to another, we could take PONKE. Thanks to the use of social media and the quality of their content, they managed to achieve incredible numbers, which then translated into an increase in the coin's price. Kekec came before PONKE, but that doesn't necessarily mean it's better than PONKE. I believe PONKE is unbeatable in terms of content, but I want to make you reflect on an important point. PONKE came after KEKEC, and after PONKE's success, many coins have emerged trying to imitate it. One of KEKEC's strengths, in my opinion, is precisely the fact that it leverages social media without being a copy-paste. Instead, it is a unique meme derived from a 90's film, and it uses a unique form of content. In short, KEKEC > KEKEC and no one else. I want to conclude by suggesting you follow them on Instagram and evaluate not only the exponential growth of their followers day by day but also observe how the views of each reel increase accordingly. Pay special attention to the comments. Many of the people commenting have no idea what it is, and you can see from the comments how Kekec generates particular emotions in people—strange but still emotions. Personally, I believe that when something is unique and even very strange, it needs time to be adopted. However, once it happens, it usually explodes and spreads like never before. A few days ago, a Kekec video was posted by a very popular meme page. They probably don't know what Kekec is about but thought the video could spark interest among their followers. How many other pages will do the same? Lastly, but not least, I want to point out how Kekec maintains a good market cap despite everything that has happened in the crypto world since October 2023. As far as I know and have personally observed, everything is extremely organic. There is no cabal behind it, and the quality is not reflected in a single jpeg but in work that has been ongoing daily for months. Every day they work harder, and the quality of their videos grows as well. I have no affiliations with the team, but I believe that Kekec truly deserves more in this world where we push celebrity or cabal-backed coins to hundreds of millions in market cap. I keep buying because the numbers suggest so. Don't just evaluate the chart (price), evaluate the data (value). BÂLKÂN DWÂRF

"PRICE IS WHAT YOU PAY. VALUE IS WHAT YOU GET." I keep buying $Kekec and I have a strong conviction. Here's Why: While the market is down, and Kekec is declining with it, there are data points that few are considering. Kekec borned in October and since then has been posting a different and original 30-second video every day, which I find extremely funny. For the past couple of months, they have also been posting daily on Instagram, and the attention on Kekec (which doesn't present itself on social media as a memecoin) is growing, moreover, it's increasing exponentially. The number of followers is increasing by about 500-1000 a day. This is largely due to the fact that they are not just focused on the main account but have several others that post reels and redirect to the main one. In short, an excellent strategy to keep growing more and more. Instagram link: Guess What? Not only are the followers increasing, but the team's workload is also growing. In fact, for a little over a month, they have also started pushing on YouTube, and the data here is promising as well. YouTube link: If we want to make a comparison, we can take Pudgy Penguins as an example, which has shown it can reach millions and millions of users without mentioning that they are a WEB3 company that owns an NFT collection. Or, if we want to be more appropriate by comparing one memecoin to another, we could take PONKE. Thanks to the use of social media and the quality of their content, they managed to achieve incredible numbers, which then translated into an increase in the coin's price. Kekec came before PONKE, but that doesn't necessarily mean it's better than PONKE. I believe PONKE is unbeatable in terms of content, but I want to make you reflect on an important point. PONKE came after KEKEC, and after PONKE's success, many coins have emerged trying to imitate it. One of KEKEC's strengths, in my opinion, is precisely the fact that it leverages social media without being a copy-paste. Instead, it is a unique meme derived from a 90's film, and it uses a unique form of content. In short, KEKEC > KEKEC and no one else. I want to conclude by suggesting you follow them on Instagram and evaluate not only the exponential growth of their followers day by day but also observe how the views of each reel increase accordingly. Pay special attention to the comments. Many of the people commenting have no idea what it is, and you can see from the comments how Kekec generates particular emotions in people—strange but still emotions. Personally, I believe that when something is unique and even very strange, it needs time to be adopted. However, once it happens, it usually explodes and spreads like never before. A few days ago, a Kekec video was posted by a very popular meme page. They probably don't know what Kekec is about but thought the video could spark interest among their followers. How many other pages will do the same? Lastly, but not least, I want to point out how Kekec maintains a good market cap despite everything that has happened in the crypto world since October 2023. As far as I know and have personally observed, everything is extremely organic. There is no cabal behind it, and the quality is not reflected in a single jpeg but in work that has been ongoing daily for months. Every day they work harder, and the quality of their videos grows as well. I have no affiliations with the team, but I believe that Kekec truly deserves more in this world where we push celebrity or cabal-backed coins to hundreds of millions in market cap. I keep buying because the numbers suggest so. Don't just evaluate the chart (price), evaluate the data (value). BÂLKÂN DWÂRF

m0ment0

133,194 次观看 • 2 年前

I'd be careful in how you talk about this subject. It is very easy, even if you are familiar with it, to spread misinformation. The Vril Droning process involves cloning and exposing the clone to a Vril parasite that takes over the central nervous system. It is very possible. It is said to be one of the darkest masonic secrets, and that they inhabit the hollow earth through the entrance in Antarctica. I find it really interesting, but it could just be something created to excuse behaviors. I have a video that explains how they actually use adrenochrome for nutrition. It is a theory but I think it has some ground to stand on. It is said that it is the reason for the floods/storms because they are waging war on them and they inhabit the deep underground bases. It is a subterranean war. It is a fun subject to talk about.

I'd be careful in how you talk about this subject. It is very easy, even if you are familiar with it, to spread misinformation. The Vril Droning process involves cloning and exposing the clone to a Vril parasite that takes over the central nervous system. It is very possible. It is said to be one of the darkest masonic secrets, and that they inhabit the hollow earth through the entrance in Antarctica. I find it really interesting, but it could just be something created to excuse behaviors. I have a video that explains how they actually use adrenochrome for nutrition. It is a theory but I think it has some ground to stand on. It is said that it is the reason for the floods/storms because they are waging war on them and they inhabit the deep underground bases. It is a subterranean war. It is a fun subject to talk about.

Mofobian

127,903 次观看 • 1 年前

even so, I trust that any new watcher will be able to pick up what's going on. The people who made the OVAs shown from time and time again that they have faith in their viewers that they'll be able to understand the world building that culminated to this point. You can start the other shows prior to this, either before or after this OVA and it will still feel like a proper climax leading up to this. The story beats in this show are pretty good in the sense that anyone can understand it, it's not universally profound but it does a good job in highlighting perspectives of every side and have a glimpse at what happened that lead up to it.

even so, I trust that any new watcher will be able to pick up what's going on. The people who made the OVAs shown from time and time again that they have faith in their viewers that they'll be able to understand the world building that culminated to this point. You can start the other shows prior to this, either before or after this OVA and it will still feel like a proper climax leading up to this. The story beats in this show are pretty good in the sense that anyone can understand it, it's not universally profound but it does a good job in highlighting perspectives of every side and have a glimpse at what happened that lead up to it.

delty

41,464 次观看 • 1 年前

Hi everyone Great news, we have sucesfully cashed out all the money from the wallet that the mom gave us, and this morning me and my brother, went to their village to give them the money in exchange for the solanas raised It took some effort and help from 28. Jun to prove that the crypto community actually raised all this money, but luckily they managed to pull it off. With the 19 000$ that we have raised + what 28Jun has raised, we have purchased a new home for them in their village ( il get the photos of that too) , as this one was not in great condition and it is too small for such a big family. I would like to thank u all for participating and proving that when its a good cause, we can all come together and help, no matter the country, race or nationality Here are some photos i took from this beautiful family

Hi everyone Great news, we have sucesfully cashed out all the money from the wallet that the mom gave us, and this morning me and my brother, went to their village to give them the money in exchange for the solanas raised It took some effort and help from 28. Jun to prove that the crypto community actually raised all this money, but luckily they managed to pull it off. With the 19 000$ that we have raised + what 28Jun has raised, we have purchased a new home for them in their village ( il get the photos of that too) , as this one was not in great condition and it is too small for such a big family. I would like to thank u all for participating and proving that when its a good cause, we can all come together and help, no matter the country, race or nationality Here are some photos i took from this beautiful family

Reljoo

57,301 次观看 • 7 个月前

Scientists are baffled by this. The Bacterial Flagellum is composed of 20-30 unique parts. Combined, they total over 30,000 parts that make this little motor run. It can hit rotation speeds of up to 100,000 RPM, then stop & reverse direction in a quarter of a turn. It can propel a bacteria up to 20 lengths per second, which when scaled up is about equal to 225mph in a car. But this motor only works when all those parts are perfectly engineered and working together. Take away just one of those 30 pieces, and it stops functioning. That means it can't evolve gradually. None of the pieces do anything outside the system, and the system only works with all the pieces. Bacteria require this motor to move - without it, they would quickly die. How can anyone see something like and still deny that Life is Divinely Designed?

Scientists are baffled by this. The Bacterial Flagellum is composed of 20-30 unique parts. Combined, they total over 30,000 parts that make this little motor run. It can hit rotation speeds of up to 100,000 RPM, then stop & reverse direction in a quarter of a turn. It can propel a bacteria up to 20 lengths per second, which when scaled up is about equal to 225mph in a car. But this motor only works when all those parts are perfectly engineered and working together. Take away just one of those 30 pieces, and it stops functioning. That means it can't evolve gradually. None of the pieces do anything outside the system, and the system only works with all the pieces. Bacteria require this motor to move - without it, they would quickly die. How can anyone see something like and still deny that Life is Divinely Designed?

Divinely Designed

96,426 次观看 • 2 个月前

The bacterial flagellum looks like a simple tail, or whip. But it’s actually a rotating motor, and perhaps the most sophisticated protein complex nature has ever evolved. In e. coli, these motors are capable of astonishing speeds; about 15,000 rpm. (The world record, according to one study, is for a Vibrio cell that was “clocked at 100,000 rpm by laser microscopy.) The flagellum propels the cell forward at speeds of 20-30 microns per second, or roughly 15 body lengths per second. If scaled up to the size of a cheetah, E. coli would *nearly* be the fastest land organism. The darting movements of a microbe were first observed in 1676 by Antony van Leeuwenhoek, a Dutch cloth merchant. Antony was delighted by the motion of his “animalcules,” writing: “I must say, for my part, that no more pleasant sight has ever yet come before my eye than these many thousands of living creatures, seen all alive in a little drop of water, moving among one another, each several creature having its own proper motion.” But Leeuwenhoek did not see flagella. He assumed, rather, that these animalcules must be “furnished with paws” instead. Christian Ehrenberg would not properly describe flagella until 1836. But amazingly, all the way up until the 1970s, nobody actually knew how the flagellum spun! In 1973, there were two competing models people argued over: the helical-wave (bending) model and the rotating (corkscrew) model. The first model suggested that the flagellum whipped back and forth, side-to-side, to propel the cell like paddle. The corkscrew model suggested that the whole flagellum instead spins around like a screw. In 1974, the corkscrew model finally won out. For two separate studies, scientists affixed flagella to glass slides using antibodies, and watched as the cells spun around and around like corkscrews. And finally, in just the last year, high-resolution structures of the flagellum have revealed a LOT more about its intricate assembly. The tail is made from ~20,000 self-assembling copies of a single protein, called flagellin. A “driveshaft,” or rod, spins the tail and is itself made of 26 protein subunits. Each “motor” in E. coli consists of 11 stators, each of which is made from 7 proteins.(Other types of cells have even more stators, and swim with much higher torques.) The flagellum spins when protons flow into the cell through tiny channels in these stators; akin to water running through a turbine. Each proton makes a small part of the stator change shape and push against the rotor, nudging it forward one step. With dozens of stators working at once, these nudges quickly spin the propeller. I'm writing an essay for Asimov Press about this now, and am really enjoying learning about the flagellum and its history. It's an extraordinarily complicated structure, though, and has been a challenge to understand!

The bacterial flagellum looks like a simple tail, or whip. But it’s actually a rotating motor, and perhaps the most sophisticated protein complex nature has ever evolved. In e. coli, these motors are capable of astonishing speeds; about 15,000 rpm. (The world record, according to one study, is for a Vibrio cell that was “clocked at 100,000 rpm by laser microscopy.) The flagellum propels the cell forward at speeds of 20-30 microns per second, or roughly 15 body lengths per second. If scaled up to the size of a cheetah, E. coli would nearly be the fastest land organism. The darting movements of a microbe were first observed in 1676 by Antony van Leeuwenhoek, a Dutch cloth merchant. Antony was delighted by the motion of his “animalcules,” writing: “I must say, for my part, that no more pleasant sight has ever yet come before my eye than these many thousands of living creatures, seen all alive in a little drop of water, moving among one another, each several creature having its own proper motion.” But Leeuwenhoek did not see flagella. He assumed, rather, that these animalcules must be “furnished with paws” instead. Christian Ehrenberg would not properly describe flagella until 1836. But amazingly, all the way up until the 1970s, nobody actually knew how the flagellum spun! In 1973, there were two competing models people argued over: the helical-wave (bending) model and the rotating (corkscrew) model. The first model suggested that the flagellum whipped back and forth, side-to-side, to propel the cell like paddle. The corkscrew model suggested that the whole flagellum instead spins around like a screw. In 1974, the corkscrew model finally won out. For two separate studies, scientists affixed flagella to glass slides using antibodies, and watched as the cells spun around and around like corkscrews. And finally, in just the last year, high-resolution structures of the flagellum have revealed a LOT more about its intricate assembly. The tail is made from ~20,000 self-assembling copies of a single protein, called flagellin. A “driveshaft,” or rod, spins the tail and is itself made of 26 protein subunits. Each “motor” in E. coli consists of 11 stators, each of which is made from 7 proteins.(Other types of cells have even more stators, and swim with much higher torques.) The flagellum spins when protons flow into the cell through tiny channels in these stators; akin to water running through a turbine. Each proton makes a small part of the stator change shape and push against the rotor, nudging it forward one step. With dozens of stators working at once, these nudges quickly spin the propeller. I'm writing an essay for Asimov Press about this now, and am really enjoying learning about the flagellum and its history. It's an extraordinarily complicated structure, though, and has been a challenge to understand!

Niko McCarty.

51,893 次观看 • 11 个月前

The Sabotaging Practice of Over Supply and Sameness in the NFT Space. The current zeitgeist of the NFT space is that the same artists are doing the same kind of work five times a year, with project after project leaving a trail of disappointment and discontent among collectors and all of us watching in disbelief as huge resources are extracted from the space over work that feels like it could be left as an "artist study." I understand that you can do what you want with your money as collectors, but we are killing the whole space with this incestuous practice. No artist is that prolific to be able to do 5 collections of 100+ pieces each every year and actually deliver innovation and some kind of creative evolution. Of course, they can pretend play that the work has something new, but there is no precedent nor proof that that has ever happened in the speed that it happens in the NFT space. Again, people are free to through away their resources on whatever they want but with this way of doing things, we more and more are going to start seeing the consequences. Oh! There are consequences? Yes. Maybe unintended, but there are. Let's see. Let's start with the loss of belief in the NFT space as somewhere where emerging artists can come and find support for their experiments. Why even bother to bring experiments, innovation, and new ways to think of art on the blockchain if the same people have all the collectors hypnotized with their magical flutes? Why even try to come to a space where taking risks and challenging the status quo (the mission of art!!!) is overlooked? This makes the NFT space a social club and not a space for art. I guess it is fine, but IMO it is a recipe for disaster. New collectors stay away because the art will slowly but surely become stale and un-challenging. Why even bother to come and see what is happening here if you can't, as a collector, see new weird and up-and-coming artists? The amount of noise emitted by the same artists doing the same art over and over, drowns out any new voices. Again. A recipe for disaster. The NFT space is becoming a space of disappointment and doubt. We think that collections going to zero one after the other, over and over, is not damaging? I feel we are kidding ourselves. Disappointment piles up, and again, the people who will hurt are the emerging artists, the new blood, the ones who are willing to risk the most and, in return, put fire in this cold space of sameness. I love this space—don't get me wrong—it has changed my life, and I believe it has a ton of potential, but things need to change for it to become a beacon of light in art. But we need to support new voices. We need to support new ideas. The challenge is huge. I hope to contribute all I can to this change. I hope more and more see how exciting it is to go out and try to discover what else is out there and move this space forward. But again, I understand the leaps of faith needed, but if there is a space that is based on that, it's the NFT space...so there is hope. We will see. 📺by Boldtron

The Sabotaging Practice of Over Supply and Sameness in the NFT Space. The current zeitgeist of the NFT space is that the same artists are doing the same kind of work five times a year, with project after project leaving a trail of disappointment and discontent among collectors and all of us watching in disbelief as huge resources are extracted from the space over work that feels like it could be left as an "artist study." I understand that you can do what you want with your money as collectors, but we are killing the whole space with this incestuous practice. No artist is that prolific to be able to do 5 collections of 100+ pieces each every year and actually deliver innovation and some kind of creative evolution. Of course, they can pretend play that the work has something new, but there is no precedent nor proof that that has ever happened in the speed that it happens in the NFT space. Again, people are free to through away their resources on whatever they want but with this way of doing things, we more and more are going to start seeing the consequences. Oh! There are consequences? Yes. Maybe unintended, but there are. Let's see. Let's start with the loss of belief in the NFT space as somewhere where emerging artists can come and find support for their experiments. Why even bother to bring experiments, innovation, and new ways to think of art on the blockchain if the same people have all the collectors hypnotized with their magical flutes? Why even try to come to a space where taking risks and challenging the status quo (the mission of art!!!) is overlooked? This makes the NFT space a social club and not a space for art. I guess it is fine, but IMO it is a recipe for disaster. New collectors stay away because the art will slowly but surely become stale and un-challenging. Why even bother to come and see what is happening here if you can't, as a collector, see new weird and up-and-coming artists? The amount of noise emitted by the same artists doing the same art over and over, drowns out any new voices. Again. A recipe for disaster. The NFT space is becoming a space of disappointment and doubt. We think that collections going to zero one after the other, over and over, is not damaging? I feel we are kidding ourselves. Disappointment piles up, and again, the people who will hurt are the emerging artists, the new blood, the ones who are willing to risk the most and, in return, put fire in this cold space of sameness. I love this space—don't get me wrong—it has changed my life, and I believe it has a ton of potential, but things need to change for it to become a beacon of light in art. But we need to support new voices. We need to support new ideas. The challenge is huge. I hope to contribute all I can to this change. I hope more and more see how exciting it is to go out and try to discover what else is out there and move this space forward. But again, I understand the leaps of faith needed, but if there is a space that is based on that, it's the NFT space...so there is hope. We will see. 📺by Boldtron

alejandro cartagena

98,261 次观看 • 2 年前