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There's a bacteriophage that turns bacteria into “liquid crystals.” Specifically, Pseudomonas aeruginosa bacteria make Pf phages, which are rod-shaped, negatively-charged, and measure about 2 micrometers in length (roughly the length of an E. coli cell). These phages leave the cells and enter their surroundings. There, they mix with polymers,... also secreted by the cells, to form a crystalline matrix. Surprisingly, this is good for the cells. Although the phages kill some of them, it also makes their biofilms stickier and able to withstand certain antibiotics. These bacteria + phages are prevalent in cystic fibrosis patients; they've formed a sort of symbiotic relationship. The Pf phages are made from thousands of repeating copies of a coat protein, called CoaB, which wraps around a single-stranded, circular DNA genome. These genes are integrated directly on the bacterial chromosome. The bacteria “turn on” these phage genes when placed in a viscous environment with low oxygen levels. This is like a trigger to start forming a biofilm. And the cells make a lot of phages; about 100 billion per milliliter. These liquid crystals form because of a physics principle called “depletion attraction.” If you just mix a bunch of loose or flexible polymers together (such as long carbon chains) they will not form a liquid crystal. But if you mix stiff rods (the phages) with loose polymers at a high enough concentration, the polymers will force the phages close together to create a material that flows like a liquid despite being ordered like a crystal. See the video below. These liquid crystal biofilms are hard to get rid of. The negatively-charged phages block many antibiotics (like aminoglycosides, which are positively-charged) from entering cells. Liquid crystals also retain water, so these biofilms can survive on drier surfaces. I first heard about this from Malmesbury’s excellent newsletter, called “Telescopic Turnip.”show more

Niko McCarty.

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50,257 views • 8 months ago •via X (Twitter)

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Some microbes carry a protein, called SNIPE, that "chops up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.

Some microbes carry a protein, called SNIPE, that "chops up" phage DNA as it's being injected into the cell. This is a new mechanism for phage defense! CRISPR–Cas and restriction enzymes also evolved to fight against phages, but they work by recognizing sequences. SNIPE works, instead, by sensing "touch." SNIPE is a protein with about 500 amino acids. After it's made by the ribosome, it latches onto ManYZ, two proteins which sit on the cell's inner membrane. (ManYZ is an importer; it brings mannose and other sugars into the cell.) Once attached to ManYZ, SNIPE sits and waits for an invading phage. Some phages, including lambda, actually infect cells by pushing their DNA through this ManYZ channel. Lambda uses its "tail" to reach inside the protein channel, basically, and inject its DNA. When this physical touch happens, though, SNIPE is waiting. As soon as the phage DNA starts entering the cell, and passes through ManYZ and SNIPE, it gets immediately destroyed. This means that SNIPE is the first phage defense system discovered, so far, that uses spatial positioning at the injection site to destroy invaders. But there are caveats, of course. If you untether SNIPE from ManYZ, such that it can freely diffuse through the cell, it will chew up the bacterium's genome. It is not a highly discerning nuclease! Also, SNIPE is not found in most bacteria. A prior pangenome study, which sequenced lots of different microbes, found that roughly a third of well-studied bacterial lineages had at least one member with a SNIPE-like protein. (For this paper, they just ported one of those homologs into an E. coli laboratory strain.) And finally, because SNIPE's mechanism is tightly tied to ManYZ, it cannot be used to defend against phages that enter the cell through different routes. T4 phages, for example, inject their DNA straight through the cell membrane and into the cytoplasm, without interacting with ManYZ. This is a nice basic science paper. Applications TBD. (Just remember that scientists figured out that bacteria had a phage defense system, called CRISPR-Cas, many years before it was repurposed into a gene-editing tool.) P.S. The video below shows how cells with the SNIPE gene (middle row) kill invading phages, and thus continue growing and dividing. Empty vector (top row) refers to bacteria carrying a plasmid with no SNIPE gene; this is a control group. And SNIPE E414A refers to cells which received a mutated SNIPE gene, where the glutamate at position 414 has been changed to an alanine, thus destroying the protein's nuclease activity. These cells also die when they get infected with a phage.

Niko McCarty.

20,536 views • 6 months ago

A single E. coli cell, placed on a dish, will become 70 billion cells in just 12 hours. That’s exponential growth. But a new preprint shows that it's possible to engineer E. coli to grow linearly instead, where only one daughter cell continues dividing and the other stops. First, some context. In nature, there is a bacterium called Mycobacterium smegmatis (initially discovered in 1884 in ulcers scraped from syphilis patients.) M. smegmatis is weird because it divides asymmetrically. These cells grow only from one end, and all their cell wall biosynthesis machinery is located on that one end. So when the cell divides, one daughter gets this machinery and the other gets nothing. The daughter that gets the machinery can keep dividing immediately, but the other daughter has to remake all that machinery from scratch, so its growth is delayed. E. coli doesn’t grow like this. When it divides, it pinches in the middle and splits everything evenly. Enzymes, metabolites, and proteins get partitioned more or less randomly between the two daughters. For the new preprint, though, researchers engineered E. coli to behave more like M. smegmatis. Here is how they did it: First, they deleted a gene called cyaA, which encodes an enzyme (adenylate cyclase) that makes a molecule called cAMP. cAMP is SUPER IMPORTANT! It is a nutrient sensor that instructs E. coli to switch on genes that help it digest non-glucose carbon sources when glucose is scarce. Without cAMP, E. coli cells growing on alternative carbon sources will starve; they won’t know how to eat the food. Next, they added back a “split” version of the cyaA gene into the cells. In other words, they split the gene in two so that each half of the enzyme is made separately. Cells can only make cAMP, and thus eat non-glucose carbon sources, if these two halves come together. To facilitate that “coming together,” the researchers also fused the split cyaA proteins to sticky proteins that clump together, and to a fluorescent protein (to make it easy to track these molecules in the cell.) So now some interesting things start to happen if you grow E. coli on a growth medium lacking glucose. As the cell grows, its cyaA “halves” start clumping together into a giant ball. Inside the aggregate, the two enzyme halves come together and make cAMP. And when the cell gets big enough and divides, the clump of cyaA RANDOMLY goes to either daughter cell #1 or #2. The daughter that gets the aggregate (called PA+ in this paper) can keep dividing. The daughter that doesn’t (PA–) cannot. It still grows a few times — about four divisions — because it inherits some leftover cAMP from its mother. But after that, the metabolite is diluted away, and the cell stops growing. PA+ cells went through about 23 divisions on average before their aggregate decayed. And the population of cells, as a whole, grew linearly. This paper is cool because there are many applications where exponential growth is too unpredictable and, perhaps, unsafe. If you want to engineer bacteria to deliver drugs, clean up waste, or live in the gut, you don’t want them to double uncontrollably. This paper shows you can make them expand in a controlled, linear way. Alas, mutations could break this whole engineered system. A mutation that restores cyaA, for example, would give cells a new way to make cAMP. Mutations that make the aggregates split between daughters would break the asymmetry, too. But still, I really enjoy proof-of-concept engineering papers like this.

A single E. coli cell, placed on a dish, will become 70 billion cells in just 12 hours. That’s exponential growth. But a new preprint shows that it's possible to engineer E. coli to grow linearly instead, where only one daughter cell continues dividing and the other stops. First, some context. In nature, there is a bacterium called Mycobacterium smegmatis (initially discovered in 1884 in ulcers scraped from syphilis patients.) M. smegmatis is weird because it divides asymmetrically. These cells grow only from one end, and all their cell wall biosynthesis machinery is located on that one end. So when the cell divides, one daughter gets this machinery and the other gets nothing. The daughter that gets the machinery can keep dividing immediately, but the other daughter has to remake all that machinery from scratch, so its growth is delayed. E. coli doesn’t grow like this. When it divides, it pinches in the middle and splits everything evenly. Enzymes, metabolites, and proteins get partitioned more or less randomly between the two daughters. For the new preprint, though, researchers engineered E. coli to behave more like M. smegmatis. Here is how they did it: First, they deleted a gene called cyaA, which encodes an enzyme (adenylate cyclase) that makes a molecule called cAMP. cAMP is SUPER IMPORTANT! It is a nutrient sensor that instructs E. coli to switch on genes that help it digest non-glucose carbon sources when glucose is scarce. Without cAMP, E. coli cells growing on alternative carbon sources will starve; they won’t know how to eat the food. Next, they added back a “split” version of the cyaA gene into the cells. In other words, they split the gene in two so that each half of the enzyme is made separately. Cells can only make cAMP, and thus eat non-glucose carbon sources, if these two halves come together. To facilitate that “coming together,” the researchers also fused the split cyaA proteins to sticky proteins that clump together, and to a fluorescent protein (to make it easy to track these molecules in the cell.) So now some interesting things start to happen if you grow E. coli on a growth medium lacking glucose. As the cell grows, its cyaA “halves” start clumping together into a giant ball. Inside the aggregate, the two enzyme halves come together and make cAMP. And when the cell gets big enough and divides, the clump of cyaA RANDOMLY goes to either daughter cell #1 or #2. The daughter that gets the aggregate (called PA+ in this paper) can keep dividing. The daughter that doesn’t (PA–) cannot. It still grows a few times — about four divisions — because it inherits some leftover cAMP from its mother. But after that, the metabolite is diluted away, and the cell stops growing. PA+ cells went through about 23 divisions on average before their aggregate decayed. And the population of cells, as a whole, grew linearly. This paper is cool because there are many applications where exponential growth is too unpredictable and, perhaps, unsafe. If you want to engineer bacteria to deliver drugs, clean up waste, or live in the gut, you don’t want them to double uncontrollably. This paper shows you can make them expand in a controlled, linear way. Alas, mutations could break this whole engineered system. A mutation that restores cyaA, for example, would give cells a new way to make cAMP. Mutations that make the aggregates split between daughters would break the asymmetry, too. But still, I really enjoy proof-of-concept engineering papers like this.

Niko McCarty.

58,047 views • 1 year ago

S-Shaped Herkimer "Diamond" Chain This specimen is unique because it has gemmy Smoky Quartz surrounding a clear Quartz crystal in the center and an aesthetic S-shape. Herkimer "Diamonds" are a variety of Quartz found in Herkimer, New York. These are nicknamed "Diamonds" because of their incredible brilliance and their chunky, double terminated shape that resembles a diamond. Mining for these crystals is very difficult because they are embedded in hard rock which requires lots of work to find small quantities and they are rarely found in long chains like this with excellent clarity.

S-Shaped Herkimer "Diamond" Chain This specimen is unique because it has gemmy Smoky Quartz surrounding a clear Quartz crystal in the center and an aesthetic S-shape. Herkimer "Diamonds" are a variety of Quartz found in Herkimer, New York. These are nicknamed "Diamonds" because of their incredible brilliance and their chunky, double terminated shape that resembles a diamond. Mining for these crystals is very difficult because they are embedded in hard rock which requires lots of work to find small quantities and they are rarely found in long chains like this with excellent clarity.

Rocks for the Spirit

17,963 views • 4 months ago

Inside every cell, there is a transport system that determines how materials move, signals propagate, and structure is maintained. This video captures that system in motion. The glowing streaks mark the growing ends of microtubules (protein polymers that constantly assemble and disassemble through a process called dynamic instability). Rather than forming permanent tracks, microtubules are rebuilt continuously, allowing cells to reorganize their internal layout in real time. This behavior is essential for life. Cells rely on microtubule dynamics to divide accurately, migrate during development and repair, and maintain long-distance transport in neurons that may span over a meter in length. When this system is altered, the consequences are significant. Certain cancer therapies work by locking microtubules in place, preventing cell division. In contrast, failures in microtubule transport are linked to neurodegenerative conditions (like Alzheimer's) where intracellular delivery breaks down. What appears as abstract motion under a microscope is actually one of the core systems that keeps cells functional, adaptable, and alive. Video Credit: Andy Moore

Inside every cell, there is a transport system that determines how materials move, signals propagate, and structure is maintained. This video captures that system in motion. The glowing streaks mark the growing ends of microtubules (protein polymers that constantly assemble and disassemble through a process called dynamic instability). Rather than forming permanent tracks, microtubules are rebuilt continuously, allowing cells to reorganize their internal layout in real time. This behavior is essential for life. Cells rely on microtubule dynamics to divide accurately, migrate during development and repair, and maintain long-distance transport in neurons that may span over a meter in length. When this system is altered, the consequences are significant. Certain cancer therapies work by locking microtubules in place, preventing cell division. In contrast, failures in microtubule transport are linked to neurodegenerative conditions (like Alzheimer's) where intracellular delivery breaks down. What appears as abstract motion under a microscope is actually one of the core systems that keeps cells functional, adaptable, and alive. Video Credit: Andy Moore

William A. Wallace, Ph.D.

18,469 views • 6 months ago

If you have Cancer, this is your visualization. That is a cancerous cell reaching Apoptosis and Necrosis—they are gone. — Natural Killer (NK) cells play a the primary role in the immune system's defense against cancer. They induce cancer cell death primarily through two mechanisms: Apoptosis Necrosis Apoptosis is a programmed, non-inflammatory form of cell death, while necrosis is a more abrupt and inflammatory process. In many cases, NK cells can trigger a combination of both, leading to mixed forms of cell death. This dual capability allows NK cells to effectively target and destroy all tumor cells. Their ability to act without prior sensitization makes them vital for early cancer surveillance and curing existing cancer. One of the only ways cancer never starts or stops entirely is NK cells. They are the guerrilla warfare troops that never sleep. This is why it is vital for BioShield by to be approved, NOW for every cancer, not just a single cancer type. With the rest needing years and years of tests. Cancer is cancer, unregulated cell division and NK cells are NK cells. The ONLY thing that stops BioShield is government betrayal, and organized corruption disguised as following the “regulations” designed by the entrenched gatekeepers of corporate protection. Everyone knows it works that has even a molecule of biological understanding. Now you know.

If you have Cancer, this is your visualization. That is a cancerous cell reaching Apoptosis and Necrosis—they are gone. — Natural Killer (NK) cells play a the primary role in the immune system's defense against cancer. They induce cancer cell death primarily through two mechanisms: Apoptosis Necrosis Apoptosis is a programmed, non-inflammatory form of cell death, while necrosis is a more abrupt and inflammatory process. In many cases, NK cells can trigger a combination of both, leading to mixed forms of cell death. This dual capability allows NK cells to effectively target and destroy all tumor cells. Their ability to act without prior sensitization makes them vital for early cancer surveillance and curing existing cancer. One of the only ways cancer never starts or stops entirely is NK cells. They are the guerrilla warfare troops that never sleep. This is why it is vital for BioShield by to be approved, NOW for every cancer, not just a single cancer type. With the rest needing years and years of tests. Cancer is cancer, unregulated cell division and NK cells are NK cells. The ONLY thing that stops BioShield is government betrayal, and organized corruption disguised as following the “regulations” designed by the entrenched gatekeepers of corporate protection. Everyone knows it works that has even a molecule of biological understanding. Now you know.

Brian Roemmele

191,436 views • 9 months ago

See these images? These boxes of aid and piles of food are in the same place where the UN announced famine today in a report in which the UN lowered their standard so that they can claim there is a famine. These are images from today’s aid distribution in northern Gaza, piles of food left on the ground by civilians.❗️ This distribution site is where civilians from Gaza City receive aid. In addition to their false report, the UN also “lost count” of 6,000 trucks in the last three months.

See these images? These boxes of aid and piles of food are in the same place where the UN announced famine today in a report in which the UN lowered their standard so that they can claim there is a famine. These are images from today’s aid distribution in northern Gaza, piles of food left on the ground by civilians.❗️ This distribution site is where civilians from Gaza City receive aid. In addition to their false report, the UN also “lost count” of 6,000 trucks in the last three months.

LTC Ariella Mazor

20,361 views • 1 year ago

Wondering if you are “quad dominant” in your throw and if you should change it? Maybe you shouldn’t 🤷‍♂️ A coach’s post coming from Austin Roark 🚀⠀⁠ -⠀⁠ One question I get from a lot of athletes is whether they should change their lower half because their knee is over their toe during their loading phase down the mound. ⠀⁠ -⠀⁠ The biggest thing that I look for when trying to figure out if it is an issue or not is to see how they are able to get out of that position. Some guys are able to leverage and rotate from that position extremely well, which then I would say that it’s not an issue.⠀⁠ -⠀⁠ On the other hand, there are some guys who will get out of this position by driving extension out of their back leg, killing their ability to rotate their pelvis and get it in an open position into landing.⠀⁠ -⠀⁠ This is when I would suggest trying to make a change. I think a lot of people jump into certain ideologies that you shouldn’t do certain things because it’s “inefficient” or it looks “wrong”. ⠀⁠ -⠀⁠ Take a look at these pitchers shown in the video. All 3 of these high level arms have some degree of knee flexion over their toe. Now, granted, they all have insane levers to help them, but the way they are moving is what makes them efficient in how they throw. ⠀⁠ -⠀⁠ I think if you told Dustin May that he had to hold a vertical shin down the mound, it would be a disaster and mess a lot of things up upstream that would impact him in a negative way.⠀⁠ -⠀⁠ The big takeaway here is that there are no absolutes. One thing that may look inefficient to you could be the thing that makes someone else very efficient.⠀⁠ -⠀⁠ When trying to figure out if you should change something about someone's delivery, make sure to look at the entire unit as a whole and don’t jump into any quick changes.

Wondering if you are “quad dominant” in your throw and if you should change it? Maybe you shouldn’t 🤷‍♂️ A coach’s post coming from Austin Roark 🚀⠀⁠ -⠀⁠ One question I get from a lot of athletes is whether they should change their lower half because their knee is over their toe during their loading phase down the mound. ⠀⁠ -⠀⁠ The biggest thing that I look for when trying to figure out if it is an issue or not is to see how they are able to get out of that position. Some guys are able to leverage and rotate from that position extremely well, which then I would say that it’s not an issue.⠀⁠ -⠀⁠ On the other hand, there are some guys who will get out of this position by driving extension out of their back leg, killing their ability to rotate their pelvis and get it in an open position into landing.⠀⁠ -⠀⁠ This is when I would suggest trying to make a change. I think a lot of people jump into certain ideologies that you shouldn’t do certain things because it’s “inefficient” or it looks “wrong”. ⠀⁠ -⠀⁠ Take a look at these pitchers shown in the video. All 3 of these high level arms have some degree of knee flexion over their toe. Now, granted, they all have insane levers to help them, but the way they are moving is what makes them efficient in how they throw. ⠀⁠ -⠀⁠ I think if you told Dustin May that he had to hold a vertical shin down the mound, it would be a disaster and mess a lot of things up upstream that would impact him in a negative way.⠀⁠ -⠀⁠ The big takeaway here is that there are no absolutes. One thing that may look inefficient to you could be the thing that makes someone else very efficient.⠀⁠ -⠀⁠ When trying to figure out if you should change something about someone's delivery, make sure to look at the entire unit as a whole and don’t jump into any quick changes.

Tread Athletics

25,070 views • 8 months ago

Kedarnath is a tremendous space. The utterance of the sound “Shiva” attains a completely new dimension and significance in Kedar. It is a space which has been specially prepared for this particular sound. When we utter the word “Shiva,” it is the freedom of the uncreated, the liberation of one who is not created. It is almost like on this planet, the sound “Shiva” emanates from this place. For thousands of years, people have experienced that space as a reverberation of that sound. This is also a place that has witnessed thousands of Yogis and mystics of every kind. When I say every kind, you cannot imagine those kinds. These are people who made no attempt to teach anything to anyone. Their way of making an offering to the world was by leaving their energies, their path, their work – everything – in a certain way in these spaces.

Kedarnath is a tremendous space. The utterance of the sound “Shiva” attains a completely new dimension and significance in Kedar. It is a space which has been specially prepared for this particular sound. When we utter the word “Shiva,” it is the freedom of the uncreated, the liberation of one who is not created. It is almost like on this planet, the sound “Shiva” emanates from this place. For thousands of years, people have experienced that space as a reverberation of that sound. This is also a place that has witnessed thousands of Yogis and mystics of every kind. When I say every kind, you cannot imagine those kinds. These are people who made no attempt to teach anything to anyone. Their way of making an offering to the world was by leaving their energies, their path, their work – everything – in a certain way in these spaces.

Sadhguru

57,781 views • 4 months ago

Brainrotting teens watching short form memes so much to the point that parts of the fragments of other memes become even more short form and get colluded in other memes to the point that it really doesnt make sense. However. Brain loves pattern recognition of these patterns and nonsensical randomly shown fragments of memes, because it is not long form reward, nor short form reward — but instantaneous; it is the only form of pleasure it can feel So brain tries to look for these patterns unconsciously, it sees patterns and similar resemblance in random things and adds a symbolical emotional labeling of truth to it. So everything becomes a piece of information and data. It gets stored in their subconscious brain and fires up everytime there is a resemblance. Extremely dangerous if weaponised but no one sees the patterns yet. However because of these pattern behaviours teens are split into two categories, the brainrots which God knows how it will end with them — consumers and slaves that later on might have no free will and be driven by pure chemical instinct. And those who see for truth in patterns. The latter is able to overcome modern day censoring and freedom of speech mechanisms, and possibly overcome the evil trying to control the world with pure silliness and having fun. (67 is part of a random pattern that someone said during a match score, and it became viral, nothing more but a collective participation to which youth finds identity by being and acting in it; “performing”) Its beauty lies not in the act but in those individuals that look beyond the chemical instincts of the lower mind. Example of the video below. It shows many fragmental elements of history, symbolism, that is collaged into art. Which by being seen individually or collectively it shows the expression on how man uses its own soul for these kind of co-creations he choses to participate in creation. Symbolism that can leave a person ask for its meaning and search for it, only by questioning himself not by a direct answer (short or long form). Of course which extreme beauty there is also extreme ugliness which are out there which I wont show here Lets see how it really turns out to be honest, West has no protection toward the subjective, the feminine, the subconscious. To which the inner sins of man try to exploit.

Brainrotting teens watching short form memes so much to the point that parts of the fragments of other memes become even more short form and get colluded in other memes to the point that it really doesnt make sense. However. Brain loves pattern recognition of these patterns and nonsensical randomly shown fragments of memes, because it is not long form reward, nor short form reward — but instantaneous; it is the only form of pleasure it can feel So brain tries to look for these patterns unconsciously, it sees patterns and similar resemblance in random things and adds a symbolical emotional labeling of truth to it. So everything becomes a piece of information and data. It gets stored in their subconscious brain and fires up everytime there is a resemblance. Extremely dangerous if weaponised but no one sees the patterns yet. However because of these pattern behaviours teens are split into two categories, the brainrots which God knows how it will end with them — consumers and slaves that later on might have no free will and be driven by pure chemical instinct. And those who see for truth in patterns. The latter is able to overcome modern day censoring and freedom of speech mechanisms, and possibly overcome the evil trying to control the world with pure silliness and having fun. (67 is part of a random pattern that someone said during a match score, and it became viral, nothing more but a collective participation to which youth finds identity by being and acting in it; “performing”) Its beauty lies not in the act but in those individuals that look beyond the chemical instincts of the lower mind. Example of the video below. It shows many fragmental elements of history, symbolism, that is collaged into art. Which by being seen individually or collectively it shows the expression on how man uses its own soul for these kind of co-creations he choses to participate in creation. Symbolism that can leave a person ask for its meaning and search for it, only by questioning himself not by a direct answer (short or long form). Of course which extreme beauty there is also extreme ugliness which are out there which I wont show here Lets see how it really turns out to be honest, West has no protection toward the subjective, the feminine, the subconscious. To which the inner sins of man try to exploit.

Rage ❉

332,451 views • 8 months ago

Many people are unaware of this but Hand Dryers get disgustingly dirty due to their design and the nasty environment they’re in All you have to do is flip the blower over These units pull air from the room and to blow on your hands. Public restrooms have high humidity, aerosolized particles from toilets like fecal matter and bacteria get airborne when flushing. So does dust, lint, soap scum, skin cells, hair, and mineral deposits from water. Over time, this stuff gets trapped inside But it gets even worse, there are real studies on this. It’s a real, well-documented issue Studies have shown hand dryers can blow out bacteria, sometimes including fecal bacteria, onto clean hands because they’re circulating contaminated air I never use these anymore

Many people are unaware of this but Hand Dryers get disgustingly dirty due to their design and the nasty environment they’re in All you have to do is flip the blower over These units pull air from the room and to blow on your hands. Public restrooms have high humidity, aerosolized particles from toilets like fecal matter and bacteria get airborne when flushing. So does dust, lint, soap scum, skin cells, hair, and mineral deposits from water. Over time, this stuff gets trapped inside But it gets even worse, there are real studies on this. It’s a real, well-documented issue Studies have shown hand dryers can blow out bacteria, sometimes including fecal bacteria, onto clean hands because they’re circulating contaminated air I never use these anymore

Wall Street Apes

1,054,575 views • 3 months ago

This fact absolutely shatters evolution. ...And makes the intelligent design in Life certain. All the systems in Life that make things function - like everything that enables birds to fly - require a whole set of complex interconnected parts. Nothing works in isolation. Something evolutionists overlook is how the nature of all these systems are intricately interconnected. Every part relies on something else to make it work. You need the whole system, down to the DNA itself, or the function fails. This coordinattion between so many systems makes step-by-step evolution all but impossible. For instance... A wing isn’t just bones and feathers (or membrane). A wing requires a certain type of hollow bones, which the alleged ancestors of birds didn't have. And wings by themselves are useless - what reproductive benefit would wings have without the accompanying systems that lead to actual flight (the simultaneous requirements for bone pneumatization, muscle attachment sites, feather or membrane development, and the regulatory changes that control all of them)? Wings without these features would be harmful. Hollow bones without flight would be detrimental. The step-by-step path leading from non-bird to flying birds is filled with easily killed, unselectable intermediates. This is where evolutionists constantly fail - they look at modification in isolation, without considering that these systems are large, interconnected networks of functional parts all working together. And it all starts at the genetic level, from the DNA itself. DNA genes code for proteins. Regulatory information organizes when these proteins are built and how much should be made. Further regulatory systems coordinate where these proteins go after they’re built. And yet more informational networks place the proteins into the final system in coordination with other proteins. Then these protein systems are fit together to make entire organs, tissues, bones, etc. All of these systems and processes are coordinated from the DNA - which means major modification like turning a fish fin into a bird wing requires many coordinated DNA changes across the entire network. One change at a time simply cannot lead to the coordination of an entire multi-part coordinated system like this. A mutation that changes one protein would need another coordinated mutation to fit that mutated protein into the right place, which would require other proteins to be mutated to fit together into that system, which would also require yet more regulatory mutations to keep everything coordinated... Nothing works in isolation. It's all connected. Which is why it can't evolve one step at a time. One step at a time does nothing. Life requires all or nothing systems. Only intelligence can engineer all or nothing systems.

This fact absolutely shatters evolution. ...And makes the intelligent design in Life certain. All the systems in Life that make things function - like everything that enables birds to fly - require a whole set of complex interconnected parts. Nothing works in isolation. Something evolutionists overlook is how the nature of all these systems are intricately interconnected. Every part relies on something else to make it work. You need the whole system, down to the DNA itself, or the function fails. This coordinattion between so many systems makes step-by-step evolution all but impossible. For instance... A wing isn’t just bones and feathers (or membrane). A wing requires a certain type of hollow bones, which the alleged ancestors of birds didn't have. And wings by themselves are useless - what reproductive benefit would wings have without the accompanying systems that lead to actual flight (the simultaneous requirements for bone pneumatization, muscle attachment sites, feather or membrane development, and the regulatory changes that control all of them)? Wings without these features would be harmful. Hollow bones without flight would be detrimental. The step-by-step path leading from non-bird to flying birds is filled with easily killed, unselectable intermediates. This is where evolutionists constantly fail - they look at modification in isolation, without considering that these systems are large, interconnected networks of functional parts all working together. And it all starts at the genetic level, from the DNA itself. DNA genes code for proteins. Regulatory information organizes when these proteins are built and how much should be made. Further regulatory systems coordinate where these proteins go after they’re built. And yet more informational networks place the proteins into the final system in coordination with other proteins. Then these protein systems are fit together to make entire organs, tissues, bones, etc. All of these systems and processes are coordinated from the DNA - which means major modification like turning a fish fin into a bird wing requires many coordinated DNA changes across the entire network. One change at a time simply cannot lead to the coordination of an entire multi-part coordinated system like this. A mutation that changes one protein would need another coordinated mutation to fit that mutated protein into the right place, which would require other proteins to be mutated to fit together into that system, which would also require yet more regulatory mutations to keep everything coordinated... Nothing works in isolation. It's all connected. Which is why it can't evolve one step at a time. One step at a time does nothing. Life requires all or nothing systems. Only intelligence can engineer all or nothing systems.

Divinely Designed

47,292 views • 10 days ago

🥚 Raw Eggs — They are nature's fast food, and a complete food, with every nutrient you could need. A raw egg digests in only 27 to 37 minutes, which is phenomenal compared to other foods containing protein and fat, like meat and milk. This is because egg is a fully liquid food. The body doesn't need to use any digestive fluids, hydrochloric acid, to break it down, it will absorb within the first 5 inches of the intestine only, from bacterial digestion alone. Of course, if you cook the egg, this doesn't apply anymore. Cooking not only destroys nutrients, especially enzymes and vitamins, which impairs digestion, and generates toxins, like heterocyclic amines from proteins, and cauterizes the minerals, but it coagulates the egg. This not only makes a raw egg the perfect food to get instant energy in a healthful way, but a vital food that can save someone's life. If your digestive system is so compromised you cannot digest other animal protein, like meat, raw eggs will work. Or if you have leaky gut, they digest before they even have to go through the G.I. tract. In general, if you want to give your digestive system a rest, eat raw eggs, you will get back appetite for other foods very soon. In the next post of this thread is a quote of Aajonus' most incredible testimonial on the healing power of raw eggs. They are also the best food to repair. The only thing that Aajonus found that eggs cannot do is help the body reproduce cells quicker. That takes raw meat. So long-term, you cannot replace raw meat with raw eggs, they work complementarily. Don't discard the egg white. Aajonus proved the avidin in raw egg white is not an anti-nutrient. Aajonus ate up to 60 raw eggs a day (one or two dozens on most days) since 1976. He confirmed there was no biotin deficiency whatsoever. The narrow-minded lab experiments do not explain what actually happen and then draw the wrong conclusion. What actually happens is that biotin mixes with avidin to make a compound that cleans the body of biocarbons, which are leftover byproducts from macronutrient digestion that need to be eliminated by the body. This is actually a good thing. Plus, there is an excess of available biotin in raw egg compared to the amount of avidin. It is also recommended by Aajonus to not eat raw egg yolks alone either, as it creates imbalances when on a raw diet (this doesn't apply on a cooked diet). He did the experiments on animals, feeding them raw egg white and raw egg yolk separately, and it made them extremely hungry, they required twice as much food, had huge imbalances emotionally, caused obesity, water retention, all kinds of problems. So, if you go to a restaurant, you can request the egg white to be included in your steak tartare, just like Aajonus did. What about salmonella? Salmonella is already on our skin, in our eyes, our nose, our mouth, recycling dead cells. They are beneficial bacteria, not pathogenic. Of course, this isn't medical advice. Look into Aajonus and more broadly into terrain theory vs germ theory. Don't refrigerate eggs. Only in the USA do people do this. If you wash the egg, you remove the protective membrane around it, then health departments require them to be refrigerated. Just don't wash the eggs. Eggs are a bit of a fragile food, many of its natural bacteria die when in cold temperatures, so it's better to keep them at room temperatures, or they will lose digestibility. You can blend raw eggs, however it will oxidize them, destroying certain nutrients. There are three enzymes in the egg white which prevent certain hormones that help certain diseases progress like cancer. If you as little as whip the raw egg with a work, these enzymes in the egg white oxidize within seconds. Raw eggs are a detoxification food. They are rich in cholesterol. If you drink alcohol, eat plenty of raw eggs (before, during, after), and you will avoid a hangover. The cholesterol in raw eggs is very good at collecting the alcohol and other toxins. They also enable the body to make solvents to break down toxicity like cellulite. Raw eggs can be fermented, and aged in various ways. Century eggs, the real ones (which are around 25 years old), can cost a thousand dollars. They transform in all sorts of shapes, they can look like green boiled eggs, jewelry, eggs that could belong to a dragon, or turn into white, black powder. They can give incredible energy and libido. How to eat: If you eat the raw egg white first, then the yolk right after, the raw egg will digest in 27 minutes, otherwise in 37 minutes. It is easier to do so from the shell by poking a hole on each side and sucking from it. This is "Aajonus-style". From a glass is "Rocky-style". Nowadays also called slonking. Make the egg go through your teeth while you drink it, this makes it easier to mix it with saliva, which allows better digestion. That only works if you eat only one raw egg at a time. If you eat several raw eggs at once, they will digest slower. Not an issue, it is still extremely healthy. Therefore eating raw eggs frequently throughout the day, one at a time, can bring a steady flow of nutrients to your body. Eggs are perfect to eat upon waking up, providing quick energy from fats and providing protein for the body to make glycogen from and feed the nervous system. They are perfect to eat in-between meals. Only take a couple seconds and get you going for hours, and whenever you get tired. Eggs help gain and lose weight. It all depends how you combine them. A raw egg eaten alone can lead to weight loss, except if you eat more than around 22 a day to maintain. Aajonus' weight loss protocol relies on eating a raw egg diet for 1-3 weeks and is very effective. Raw eggs can help remove cellulite, strip down toxic fat (which is fat that was used to store toxins). Eggs eaten with other foods, or several at once, don't have this weight loss effect. They are very good to eat with other foods, such as raw meat (steak tartare). You can easily eat 3 raw eggs with your raw steak. There are many recipes, from raw pastries, to sauces like mayo, milkshakes, ... where you can keep the egg raw and whole.

🥚 Raw Eggs — They are nature's fast food, and a complete food, with every nutrient you could need. A raw egg digests in only 27 to 37 minutes, which is phenomenal compared to other foods containing protein and fat, like meat and milk. This is because egg is a fully liquid food. The body doesn't need to use any digestive fluids, hydrochloric acid, to break it down, it will absorb within the first 5 inches of the intestine only, from bacterial digestion alone. Of course, if you cook the egg, this doesn't apply anymore. Cooking not only destroys nutrients, especially enzymes and vitamins, which impairs digestion, and generates toxins, like heterocyclic amines from proteins, and cauterizes the minerals, but it coagulates the egg. This not only makes a raw egg the perfect food to get instant energy in a healthful way, but a vital food that can save someone's life. If your digestive system is so compromised you cannot digest other animal protein, like meat, raw eggs will work. Or if you have leaky gut, they digest before they even have to go through the G.I. tract. In general, if you want to give your digestive system a rest, eat raw eggs, you will get back appetite for other foods very soon. In the next post of this thread is a quote of Aajonus' most incredible testimonial on the healing power of raw eggs. They are also the best food to repair. The only thing that Aajonus found that eggs cannot do is help the body reproduce cells quicker. That takes raw meat. So long-term, you cannot replace raw meat with raw eggs, they work complementarily. Don't discard the egg white. Aajonus proved the avidin in raw egg white is not an anti-nutrient. Aajonus ate up to 60 raw eggs a day (one or two dozens on most days) since 1976. He confirmed there was no biotin deficiency whatsoever. The narrow-minded lab experiments do not explain what actually happen and then draw the wrong conclusion. What actually happens is that biotin mixes with avidin to make a compound that cleans the body of biocarbons, which are leftover byproducts from macronutrient digestion that need to be eliminated by the body. This is actually a good thing. Plus, there is an excess of available biotin in raw egg compared to the amount of avidin. It is also recommended by Aajonus to not eat raw egg yolks alone either, as it creates imbalances when on a raw diet (this doesn't apply on a cooked diet). He did the experiments on animals, feeding them raw egg white and raw egg yolk separately, and it made them extremely hungry, they required twice as much food, had huge imbalances emotionally, caused obesity, water retention, all kinds of problems. So, if you go to a restaurant, you can request the egg white to be included in your steak tartare, just like Aajonus did. What about salmonella? Salmonella is already on our skin, in our eyes, our nose, our mouth, recycling dead cells. They are beneficial bacteria, not pathogenic. Of course, this isn't medical advice. Look into Aajonus and more broadly into terrain theory vs germ theory. Don't refrigerate eggs. Only in the USA do people do this. If you wash the egg, you remove the protective membrane around it, then health departments require them to be refrigerated. Just don't wash the eggs. Eggs are a bit of a fragile food, many of its natural bacteria die when in cold temperatures, so it's better to keep them at room temperatures, or they will lose digestibility. You can blend raw eggs, however it will oxidize them, destroying certain nutrients. There are three enzymes in the egg white which prevent certain hormones that help certain diseases progress like cancer. If you as little as whip the raw egg with a work, these enzymes in the egg white oxidize within seconds. Raw eggs are a detoxification food. They are rich in cholesterol. If you drink alcohol, eat plenty of raw eggs (before, during, after), and you will avoid a hangover. The cholesterol in raw eggs is very good at collecting the alcohol and other toxins. They also enable the body to make solvents to break down toxicity like cellulite. Raw eggs can be fermented, and aged in various ways. Century eggs, the real ones (which are around 25 years old), can cost a thousand dollars. They transform in all sorts of shapes, they can look like green boiled eggs, jewelry, eggs that could belong to a dragon, or turn into white, black powder. They can give incredible energy and libido. How to eat: If you eat the raw egg white first, then the yolk right after, the raw egg will digest in 27 minutes, otherwise in 37 minutes. It is easier to do so from the shell by poking a hole on each side and sucking from it. This is "Aajonus-style". From a glass is "Rocky-style". Nowadays also called slonking. Make the egg go through your teeth while you drink it, this makes it easier to mix it with saliva, which allows better digestion. That only works if you eat only one raw egg at a time. If you eat several raw eggs at once, they will digest slower. Not an issue, it is still extremely healthy. Therefore eating raw eggs frequently throughout the day, one at a time, can bring a steady flow of nutrients to your body. Eggs are perfect to eat upon waking up, providing quick energy from fats and providing protein for the body to make glycogen from and feed the nervous system. They are perfect to eat in-between meals. Only take a couple seconds and get you going for hours, and whenever you get tired. Eggs help gain and lose weight. It all depends how you combine them. A raw egg eaten alone can lead to weight loss, except if you eat more than around 22 a day to maintain. Aajonus' weight loss protocol relies on eating a raw egg diet for 1-3 weeks and is very effective. Raw eggs can help remove cellulite, strip down toxic fat (which is fat that was used to store toxins). Eggs eaten with other foods, or several at once, don't have this weight loss effect. They are very good to eat with other foods, such as raw meat (steak tartare). You can easily eat 3 raw eggs with your raw steak. There are many recipes, from raw pastries, to sauces like mayo, milkshakes, ... where you can keep the egg raw and whole.

The Primal Diet by Aajonus Vonderplanitz

23,266 views • 1 year ago

Yellow jackets, which usually nest underground and are often disturbed by a lawn mower or chainsaw, are one of the most dangerous and aggressive insects around. (Haven’t done an Entomology post lately so figured I’d throw one on) Why are they so dangerous? Because they can rapidly and repeatedly sting. This is a video I took of one who had attacked a katydid. As you can see, even as the yellow jacket begins to feed on the katydid, he continues to rapidly “pop” the prey with his stinger, pumping the paralyzing venom into the katydid. I count around 10 full stings of the prey. When a person is stung by a yellow jacket the first time, it releases an “alert pheromone”, which signals to most of the other colony members that danger is present. A major swarm of yellow jackets will then proceed out of the nest and attack the person (or animal). It takes around 1500 stings to kill a grown adult and 300-400 to kill a child. These numbers are achieved quickly with 100-200 yellow jackets swarming. If a person is allergic, they can go into anaphylactic shock with just one sting. I’m all about “saving the bees” because of their pollination factor…but Yellowjackets are one species of insect that I would gladly eliminate because of their danger. If you see them flying around the ground, or a tree stump or some rail road ties in the landscape, avoid them at all costs.

Yellow jackets, which usually nest underground and are often disturbed by a lawn mower or chainsaw, are one of the most dangerous and aggressive insects around. (Haven’t done an Entomology post lately so figured I’d throw one on) Why are they so dangerous? Because they can rapidly and repeatedly sting. This is a video I took of one who had attacked a katydid. As you can see, even as the yellow jacket begins to feed on the katydid, he continues to rapidly “pop” the prey with his stinger, pumping the paralyzing venom into the katydid. I count around 10 full stings of the prey. When a person is stung by a yellow jacket the first time, it releases an “alert pheromone”, which signals to most of the other colony members that danger is present. A major swarm of yellow jackets will then proceed out of the nest and attack the person (or animal). It takes around 1500 stings to kill a grown adult and 300-400 to kill a child. These numbers are achieved quickly with 100-200 yellow jackets swarming. If a person is allergic, they can go into anaphylactic shock with just one sting. I’m all about “saving the bees” because of their pollination factor…but Yellowjackets are one species of insect that I would gladly eliminate because of their danger. If you see them flying around the ground, or a tree stump or some rail road ties in the landscape, avoid them at all costs.

BowTiedBroke

2,208,686 views • 2 years ago

Scientists are baffled by this. The Bacterial Flagellum is composed of 20-30 unique parts. Combined, they total over 30,000 parts that make this little motor run. It can hit rotation speeds of up to 100,000 RPM, then stop & reverse direction in a quarter of a turn. It can propel a bacteria up to 20 lengths per second, which when scaled up is about equal to 225mph in a car. But this motor only works when all those parts are perfectly engineered and working together. Take away just one of those 30 pieces, and it stops functioning. That means it can't evolve gradually. None of the pieces do anything outside the system, and the system only works with all the pieces. Bacteria require this motor to move - without it, they would quickly die. How can anyone see something like and still deny that Life is Divinely Designed?

Scientists are baffled by this. The Bacterial Flagellum is composed of 20-30 unique parts. Combined, they total over 30,000 parts that make this little motor run. It can hit rotation speeds of up to 100,000 RPM, then stop & reverse direction in a quarter of a turn. It can propel a bacteria up to 20 lengths per second, which when scaled up is about equal to 225mph in a car. But this motor only works when all those parts are perfectly engineered and working together. Take away just one of those 30 pieces, and it stops functioning. That means it can't evolve gradually. None of the pieces do anything outside the system, and the system only works with all the pieces. Bacteria require this motor to move - without it, they would quickly die. How can anyone see something like and still deny that Life is Divinely Designed?

Divinely Designed

96,584 views • 3 months ago

🚨 SCIENTISTS JUST CREATED A WAY TO KILL ANTIBIOTIC-RESISTANT BACTERIA USING NOTHING BUT LIGHT. Researchers have developed graphene quantum dots that destroy over 99.9% of antibiotic-resistant S. aureus and E. coli when hit with low-intensity blue light without using any antibiotics at all. The dots work by generating reactive oxygen species that rip apart bacterial cells. After chemically modifying them, the team made the dots over 20 times more efficient, allowing them to work at very low concentrations. Because they’re made from graphene instead of toxic heavy metals, they’re also much safer for medical use. Why this matters: • Antibiotic resistance is one of the fastest-growing threats to global health • This offers a completely different weapon light instead of drugs • The dots could be used in wound dressings, creams, gels, and coatings for implants and catheters • Graphene is cheap, stable, and biocompatible The deeper implication: We’re running out of effective antibiotics, and bacteria are evolving faster than we can develop new drugs. This approach flips the script: instead of fighting bacteria with chemicals they can eventually resist, we use light to trigger a physical attack they can’t easily adapt to. If this scales, it could become a powerful new tool in the fight against superbugs especially for wound infections and medical devices, where resistant bacteria are hardest to treat. Sometimes the solution isn’t a better drug. It’s a better way to attack. Would you trust a light-activated treatment over traditional antibiotics if it worked this well? Follow for more frontier nanotechnology and breakthroughs in the fight against antibiotic resistance.

🚨 SCIENTISTS JUST CREATED A WAY TO KILL ANTIBIOTIC-RESISTANT BACTERIA USING NOTHING BUT LIGHT. Researchers have developed graphene quantum dots that destroy over 99.9% of antibiotic-resistant S. aureus and E. coli when hit with low-intensity blue light without using any antibiotics at all. The dots work by generating reactive oxygen species that rip apart bacterial cells. After chemically modifying them, the team made the dots over 20 times more efficient, allowing them to work at very low concentrations. Because they’re made from graphene instead of toxic heavy metals, they’re also much safer for medical use. Why this matters: • Antibiotic resistance is one of the fastest-growing threats to global health • This offers a completely different weapon light instead of drugs • The dots could be used in wound dressings, creams, gels, and coatings for implants and catheters • Graphene is cheap, stable, and biocompatible The deeper implication: We’re running out of effective antibiotics, and bacteria are evolving faster than we can develop new drugs. This approach flips the script: instead of fighting bacteria with chemicals they can eventually resist, we use light to trigger a physical attack they can’t easily adapt to. If this scales, it could become a powerful new tool in the fight against superbugs especially for wound infections and medical devices, where resistant bacteria are hardest to treat. Sometimes the solution isn’t a better drug. It’s a better way to attack. Would you trust a light-activated treatment over traditional antibiotics if it worked this well? Follow for more frontier nanotechnology and breakthroughs in the fight against antibiotic resistance.

TheNewPhysics

35,112 views • 2 months ago

The bacterial flagellum looks like a simple tail, or whip. But it’s actually a rotating motor, and perhaps the most sophisticated protein complex nature has ever evolved. In e. coli, these motors are capable of astonishing speeds; about 15,000 rpm. (The world record, according to one study, is for a Vibrio cell that was “clocked at 100,000 rpm by laser microscopy.) The flagellum propels the cell forward at speeds of 20-30 microns per second, or roughly 15 body lengths per second. If scaled up to the size of a cheetah, E. coli would *nearly* be the fastest land organism. The darting movements of a microbe were first observed in 1676 by Antony van Leeuwenhoek, a Dutch cloth merchant. Antony was delighted by the motion of his “animalcules,” writing: “I must say, for my part, that no more pleasant sight has ever yet come before my eye than these many thousands of living creatures, seen all alive in a little drop of water, moving among one another, each several creature having its own proper motion.” But Leeuwenhoek did not see flagella. He assumed, rather, that these animalcules must be “furnished with paws” instead. Christian Ehrenberg would not properly describe flagella until 1836. But amazingly, all the way up until the 1970s, nobody actually knew how the flagellum spun! In 1973, there were two competing models people argued over: the helical-wave (bending) model and the rotating (corkscrew) model. The first model suggested that the flagellum whipped back and forth, side-to-side, to propel the cell like paddle. The corkscrew model suggested that the whole flagellum instead spins around like a screw. In 1974, the corkscrew model finally won out. For two separate studies, scientists affixed flagella to glass slides using antibodies, and watched as the cells spun around and around like corkscrews. And finally, in just the last year, high-resolution structures of the flagellum have revealed a LOT more about its intricate assembly. The tail is made from ~20,000 self-assembling copies of a single protein, called flagellin. A “driveshaft,” or rod, spins the tail and is itself made of 26 protein subunits. Each “motor” in E. coli consists of 11 stators, each of which is made from 7 proteins.(Other types of cells have even more stators, and swim with much higher torques.) The flagellum spins when protons flow into the cell through tiny channels in these stators; akin to water running through a turbine. Each proton makes a small part of the stator change shape and push against the rotor, nudging it forward one step. With dozens of stators working at once, these nudges quickly spin the propeller. I'm writing an essay for Asimov Press about this now, and am really enjoying learning about the flagellum and its history. It's an extraordinarily complicated structure, though, and has been a challenge to understand!

The bacterial flagellum looks like a simple tail, or whip. But it’s actually a rotating motor, and perhaps the most sophisticated protein complex nature has ever evolved. In e. coli, these motors are capable of astonishing speeds; about 15,000 rpm. (The world record, according to one study, is for a Vibrio cell that was “clocked at 100,000 rpm by laser microscopy.) The flagellum propels the cell forward at speeds of 20-30 microns per second, or roughly 15 body lengths per second. If scaled up to the size of a cheetah, E. coli would nearly be the fastest land organism. The darting movements of a microbe were first observed in 1676 by Antony van Leeuwenhoek, a Dutch cloth merchant. Antony was delighted by the motion of his “animalcules,” writing: “I must say, for my part, that no more pleasant sight has ever yet come before my eye than these many thousands of living creatures, seen all alive in a little drop of water, moving among one another, each several creature having its own proper motion.” But Leeuwenhoek did not see flagella. He assumed, rather, that these animalcules must be “furnished with paws” instead. Christian Ehrenberg would not properly describe flagella until 1836. But amazingly, all the way up until the 1970s, nobody actually knew how the flagellum spun! In 1973, there were two competing models people argued over: the helical-wave (bending) model and the rotating (corkscrew) model. The first model suggested that the flagellum whipped back and forth, side-to-side, to propel the cell like paddle. The corkscrew model suggested that the whole flagellum instead spins around like a screw. In 1974, the corkscrew model finally won out. For two separate studies, scientists affixed flagella to glass slides using antibodies, and watched as the cells spun around and around like corkscrews. And finally, in just the last year, high-resolution structures of the flagellum have revealed a LOT more about its intricate assembly. The tail is made from ~20,000 self-assembling copies of a single protein, called flagellin. A “driveshaft,” or rod, spins the tail and is itself made of 26 protein subunits. Each “motor” in E. coli consists of 11 stators, each of which is made from 7 proteins.(Other types of cells have even more stators, and swim with much higher torques.) The flagellum spins when protons flow into the cell through tiny channels in these stators; akin to water running through a turbine. Each proton makes a small part of the stator change shape and push against the rotor, nudging it forward one step. With dozens of stators working at once, these nudges quickly spin the propeller. I'm writing an essay for Asimov Press about this now, and am really enjoying learning about the flagellum and its history. It's an extraordinarily complicated structure, though, and has been a challenge to understand!

Niko McCarty.

51,913 views • 1 year ago

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

Divinely Designed

166,325 views • 3 months ago

🚨🚨🚨 It doesn't really get any more real than this and you need to hear it 🚨🚨🚨 I want to introduce you to these two deadly units: The 1st FPV Strike Platoon PNK Group of the 3rd Assault Brigade of the Ukrainian Armed Forces. The Strike Unmanned Systems Platoon of the 47th Magura Separate Mechanized Brigade of the Ukrainian Armed Forces. Both of these units are the pinnacle of the world's drone warfare and part of formidable and renowned brigades; their names echo through the ranks of the Ukrainian military and chill spines throughout the ranks of the Russians. These units unleash utter devastation and death onto the Russian forces; they turn the ground the Russians walk on into a living hell, a place in which their supplies, their troops, their back-up, every thing gets deleted, their every fucking hope and dreams turn into an unimaginable shitshow of despair. If it has a pulse, a heat signature, or a set of keys, it's getting turned into fucking fairy dust around these guys. The 1st FPV Strike Platoon PNK Group of the 3rd Separate Assault Brigade provides close tactical strikes, reconnaissance, and direct-fire/loitering-munition effects in support of assault operations on the frontlines. The unit uses high-speed FPV strike drones and larger multirotor bomber drones, and is integrated with the brigade’s reconnaissance and assault companies. The Strike Unmanned Systems Platoon of the 47th “Magura” Separate Mechanized Brigade is a dedicated strike/attack unmanned-systems platoon. It conducts aerial strikes, close support to mechanized units, battlefield reconnaissance, and interdiction of light vehicles and enemy personnel using FPV strike drones and larger strike UAVs. These men work in the most dangerous areas, where they are needed the most; they oppose the biggest threats on the front lines, they cause the most devastation, but they need our help. Given the type of work that they do, they need to move fast, they need to be invisible, and strike before the enemy knows they are there and be back a camp drinking tea whilst the Russians are still collecting their comrades remains with a fucking carpet vacuum hoover. With your help I'm trying to send them 2 NAFO Truck 3.0's with the NAFO 69th Sniffing Brigade. These trucks are the 69th Brigade's newest and most kitted-out trucks made specifically for units like this. Above all, they are reliable; they have two fitted electronic-warfare drone jammers for different ranges and frequencies to protect the vehicle when it moves, it has night vision so the driver can watch a screen and drive in the pitch black as you cannot use headlights on the frontline, they have serious battery packs to run operations off when out for prolongued periods of time, they also include a spare set of heavy-duty off-road tyres to help them get through the mud to keep them mobile. These new NAFO Truck 3.0s even have FPV drone-spectrum scanners, which means if a Russian drone is in the air, they not only know it's there, they can see which type of drone it is and they can even watch the video feed that the Russians can see so they know exactly where it is. I really need your help to do this. I need you to help to spread the word, and I need you to think just for a second, is there is absolutely anything that you can donate? So many people will see this, and naturally, they will assume that everyone else will donate, but this is almost always not the case. If you want to make Russians hurt, if you want them to regret ever leaving their Russian infested shit swamps, then donate here and help these guys destroy these fucks: Pardom my French.

🚨🚨🚨 It doesn't really get any more real than this and you need to hear it 🚨🚨🚨 I want to introduce you to these two deadly units: The 1st FPV Strike Platoon PNK Group of the 3rd Assault Brigade of the Ukrainian Armed Forces. The Strike Unmanned Systems Platoon of the 47th Magura Separate Mechanized Brigade of the Ukrainian Armed Forces. Both of these units are the pinnacle of the world's drone warfare and part of formidable and renowned brigades; their names echo through the ranks of the Ukrainian military and chill spines throughout the ranks of the Russians. These units unleash utter devastation and death onto the Russian forces; they turn the ground the Russians walk on into a living hell, a place in which their supplies, their troops, their back-up, every thing gets deleted, their every fucking hope and dreams turn into an unimaginable shitshow of despair. If it has a pulse, a heat signature, or a set of keys, it's getting turned into fucking fairy dust around these guys. The 1st FPV Strike Platoon PNK Group of the 3rd Separate Assault Brigade provides close tactical strikes, reconnaissance, and direct-fire/loitering-munition effects in support of assault operations on the frontlines. The unit uses high-speed FPV strike drones and larger multirotor bomber drones, and is integrated with the brigade’s reconnaissance and assault companies. The Strike Unmanned Systems Platoon of the 47th “Magura” Separate Mechanized Brigade is a dedicated strike/attack unmanned-systems platoon. It conducts aerial strikes, close support to mechanized units, battlefield reconnaissance, and interdiction of light vehicles and enemy personnel using FPV strike drones and larger strike UAVs. These men work in the most dangerous areas, where they are needed the most; they oppose the biggest threats on the front lines, they cause the most devastation, but they need our help. Given the type of work that they do, they need to move fast, they need to be invisible, and strike before the enemy knows they are there and be back a camp drinking tea whilst the Russians are still collecting their comrades remains with a fucking carpet vacuum hoover. With your help I'm trying to send them 2 NAFO Truck 3.0's with the NAFO 69th Sniffing Brigade. These trucks are the 69th Brigade's newest and most kitted-out trucks made specifically for units like this. Above all, they are reliable; they have two fitted electronic-warfare drone jammers for different ranges and frequencies to protect the vehicle when it moves, it has night vision so the driver can watch a screen and drive in the pitch black as you cannot use headlights on the frontline, they have serious battery packs to run operations off when out for prolongued periods of time, they also include a spare set of heavy-duty off-road tyres to help them get through the mud to keep them mobile. These new NAFO Truck 3.0s even have FPV drone-spectrum scanners, which means if a Russian drone is in the air, they not only know it's there, they can see which type of drone it is and they can even watch the video feed that the Russians can see so they know exactly where it is. I really need your help to do this. I need you to help to spread the word, and I need you to think just for a second, is there is absolutely anything that you can donate? So many people will see this, and naturally, they will assume that everyone else will donate, but this is almost always not the case. If you want to make Russians hurt, if you want them to regret ever leaving their Russian infested shit swamps, then donate here and help these guys destroy these fucks: Pardom my French.

Bricktop_NAFO

24,514 views • 10 months ago