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Brain shrinkage starts at 40. Brain volume reduces by 5% every decade after the age of 40, and at a much faster rate after 70. Various strategies such as ensuring adequate sleep, minimizing stress, meditation, regular physical activity, engaging in cognitively-stimulating activities and consuming healthy foods can slow down... show more

Dr Sudhir Kumar MD DM

108,571 subscribers

418,553 views • 2 years ago •via X (Twitter)

Science & Technology Health & Wellness Education

Anya Rossi• Live Now

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10 Comments

Aparna Jaishankar2 years ago

Well I'm 81 and yes I have noted a reduction in energy but it's important to remain active and interested in most things happening around us and in the world ! And to keep reading books all the time !

Dheeraj Mehra2 years ago

Very informative advice to act now or regret later! While some of us are actively pursuing few of these strategies, time to pursue those where marks are less…🤓 Keep such knowledge coming!

Raffaele Di Giacomo, PhD2 years ago

Indeed, brain shrinkage is a natural part of aging, but it's fascinating how lifestyle choices can mitigate it. What are your thoughts on the role of diet in maintaining brain volume? #Medicine #Neuroscience For anyone seeking in-depth reviews on biomedical topics, check out It's the comprehensive platform for all your biomedical queries!

Basu-CA & RV2 years ago

How about the brain of tax professionals; Their all brain works fast and furious at fag end of due dates

JayEnAar2 years ago

Very sensible advice. Keep working, stay interested in the world around you, remain engaged, read, write, make friends, stay active.

Jyo Anand2 years ago

My simple question to you Doc….How med science calculates brain age? More the merrier here? Or vice Versa. Please answer.

Dr Sudhir Kumar MD DM2 years ago

Brain volume (size) is calculated by MRI. Brain functions are assessed by detailed neuropsychological testing and functional imaging such as PET scans.

Swaranjit Singh 🌍2 years ago

Excellent tips. I’ll add for healthy diet eat more natural fats like butter, ghee and coconut oil. Eliminate toxic seed/vegetable oils. Brain 🧠 is 60% fat in composition and needs the above for nutrition. #3SimpleSteps

ankit pareek2 years ago

Sir please share a detailed post on hypoglycemia..

OPTIONOMIX ™️2 years ago

Doctor, does that mean even intra cranial pressure also reduces along with shrinkage of brain volume?

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Exercise doesn’t just slow brain aging, it can reverse it In a year-long trial, older adults who did aerobic exercise (~65–70% max heart rate, 3x/week for 30 minutes) increased hippocampal volume by about 2%, instead of the usual 1–2% yearly shrinkage This net gain reflects neurogenesis driven in part by higher BDNF, a key protein that supports the growth and survival of new neurons The same group also showed improvements in learning and memory, underscoring how powerful regular physical activity is for the aging brain

Exercise doesn’t just slow brain aging, it can reverse it In a year-long trial, older adults who did aerobic exercise (~65–70% max heart rate, 3x/week for 30 minutes) increased hippocampal volume by about 2%, instead of the usual 1–2% yearly shrinkage This net gain reflects neurogenesis driven in part by higher BDNF, a key protein that supports the growth and survival of new neurons The same group also showed improvements in learning and memory, underscoring how powerful regular physical activity is for the aging brain

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Michael Brooks, a former teammate of mine at Harvard in 1999, passed away last November at just 45 years old. He was the second member of our team diagnosed with CTE, and the first person under age 50 in the UNITE Brain Bank diagnosed with CTE with limbic-predominant age-related TDP-43 encephalopathy (LATE), named as such because it usually doesn't appear in the brain until after age 80. If you or a loved one is struggling with symptoms of suspected CTE, the Concussion & CTE Foundation HelpLine is here for you. Reach out at to get connected with free support and resources.

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53,596 views • 1 year ago

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706,334 views • 7 months ago

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95,499 views • 2 years ago

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Of the 11 major risk factors for Alzheimer's, how many are you actively managing? According to renowned psychiatrist and brain disorder specialist Dr. Daniel Amen, a staggering 50% of Alzheimer's cases are preventable. The key, he explains, is to understand and address the 11 major risk factors, which he summarizes with the acronym BRIGHT MINDS. In a compelling discussion, Dr. Amen outlined several of these critical factors: - B is for Blood Flow: This is the #1 brain imaging predictor. Protect it by managing blood pressure, staying active, and being mindful of substances like excessive alcohol, marijuana, nicotine, and too much caffeine. - R is for Retirement & Aging: As we age, brain health requires more intention. Notably, Dr. Amen points to new research showing that marijuana use in those under 50 is associated with a 600% increased risk of heart attack, highlighting its negative impact on our blood vessels. - I is for Inflammation: A major culprit behind dementia. Combat it by avoiding ultra-processed foods, ensuring adequate Omega-3s, and surprisingly—flossing your teeth nightly to prevent gum disease and low-grade oral infections. - H is for Head Trauma: A major cause of not only psychiatric issues but also substance abuse, as it often damages the frontal lobes and impairs impulse control. - T is for Toxins: This includes drugs, alcohol, mold, and even the products we put on our bodies. Dr. Amen shared a powerful anecdote about a patient whose brain scan deteriorated significantly after general anesthesia, underscoring that it can be toxic to the brain and increase dementia risk. The takeaway is empowering: by loving your brain and taking a proactive, preventative approach to these risk factors, you can dramatically shift your cognitive future. Your brain is your most precious asset. How will you protect it today?

Camus

17,892 views • 8 months ago

This American pop rock musician, singer and songwriter from PA released ‘I Can Dream About You’ in 1984. It reached #6 on the Billboard Hot 100. He died of a brain tumor at age 43 after being diagnosed with the HIV virus. 👉🏻 Name the artist. 👉🏻 What band was he previously in? 👉🏻 What movie is the song performed in by a fictional soul group called The Sorels?

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OneOutOfFour

37,272 views • 6 months ago

In Prisons, Replacing Junk Food With Whole Foods Reduced Violence By 80%. In Juvenile Detention Centers, Replacing Junk Food With Whole Foods Reduced Violence By 91%. Food is the most powerful intervention for mental health & behavior. "If You Give Prisoners Healthy Food, Swapping Out All The Crap They Eat In Prisons, There’s A 56% Reduction In Violent Crime. If You Add A Multivitamin, It’s An 80% Reduction. Because They Are All Nutritionally Depleted." The same has been done with adolescents in juvenile detention centers with clinical trials. The kids are disruptive, violent, aggressive, oppositional & suicidal. Stopping the SAD diet filled with Ultra Processed Foods & seed oils, instead giving them whole foods, there was a 91% reduction in all violent behavior, oppositional behavior, the need for restraints went down & suicide went down 100%. Suicide is the third leading cause of death in that age group, it went down 100% — no suicides. "The SAD (Standard American Diet), full of Ultra Processed Foods, excess carbohydrates, sugar & seed oils, disconnects the Amygdala from the frontal lobe of the brain. The frontal lobe is the grown up in the room, the adult — your higher self. The Amygdala is part of your reptile brain, your lizard brain. It’s going to fight or flee. Physiologically these parts of the brain are connected. But what happens if you eat crap, they get disconnected. And so you’re constantly reacting from your Amygdala with no grownup in the room. Which is why we see this level of divisiveness and hatred & all the upheaval we’re seeing in society now. I think a large part of that has to do with our brains being constantly triggered by this reptilian insult that is driving behavior change. And when we look at the fact of other data to support this, it’s not just a theory.” ---Dr. Mark Hyman, MD A healthy diet leads to a healthy brain which leads to a healthy society. This needs to be on an individual level within our own families & on an institutional level to overhaul what's served in schools, hospitals, nursing homes, prisons & all institutional settings. 👇Prison Nutrition & Chronic Disease👇 👇Crime & Nourishment👇 👇Adolescent Good Nutrition = Good Behavior👇 Speaker: Mark Hyman, M.D. Video: truehumandiet

In Prisons, Replacing Junk Food With Whole Foods Reduced Violence By 80%. In Juvenile Detention Centers, Replacing Junk Food With Whole Foods Reduced Violence By 91%. Food is the most powerful intervention for mental health & behavior. "If You Give Prisoners Healthy Food, Swapping Out All The Crap They Eat In Prisons, There’s A 56% Reduction In Violent Crime. If You Add A Multivitamin, It’s An 80% Reduction. Because They Are All Nutritionally Depleted." The same has been done with adolescents in juvenile detention centers with clinical trials. The kids are disruptive, violent, aggressive, oppositional & suicidal. Stopping the SAD diet filled with Ultra Processed Foods & seed oils, instead giving them whole foods, there was a 91% reduction in all violent behavior, oppositional behavior, the need for restraints went down & suicide went down 100%. Suicide is the third leading cause of death in that age group, it went down 100% — no suicides. "The SAD (Standard American Diet), full of Ultra Processed Foods, excess carbohydrates, sugar & seed oils, disconnects the Amygdala from the frontal lobe of the brain. The frontal lobe is the grown up in the room, the adult — your higher self. The Amygdala is part of your reptile brain, your lizard brain. It’s going to fight or flee. Physiologically these parts of the brain are connected. But what happens if you eat crap, they get disconnected. And so you’re constantly reacting from your Amygdala with no grownup in the room. Which is why we see this level of divisiveness and hatred & all the upheaval we’re seeing in society now. I think a large part of that has to do with our brains being constantly triggered by this reptilian insult that is driving behavior change. And when we look at the fact of other data to support this, it’s not just a theory.” ---Dr. Mark Hyman, MD A healthy diet leads to a healthy brain which leads to a healthy society. This needs to be on an individual level within our own families & on an institutional level to overhaul what's served in schools, hospitals, nursing homes, prisons & all institutional settings. 👇Prison Nutrition & Chronic Disease👇 👇Crime & Nourishment👇 👇Adolescent Good Nutrition = Good Behavior👇 Speaker: Mark Hyman, M.D. Video: truehumandiet

Valerie Anne Smith

471,903 views • 1 year ago

BOOOM! “How 40 Hz Light and Sound Waves Could Halt Alzheimer’s”—MIT Groundbreaking brain research! In a series of papers starting in 2016, a collaboration led by an MIT lab has demonstrated that light flickering and/or sound clicking at 40 Hz (a technology called GENUS for Gamma Entrainment Using Sensory stimuli), reduces levels of amyloid-beta and tau proteins, prevents neuron death and preserves synapses and even sustains learning and memory in a variety of Alzheimer’s. This frequency is key to many other points of observations recently and through the past. We are seeing more and more elements where sound and light change the brain in material and repeatable ways. Link:

BOOOM! “How 40 Hz Light and Sound Waves Could Halt Alzheimer’s”—MIT Groundbreaking brain research! In a series of papers starting in 2016, a collaboration led by an MIT lab has demonstrated that light flickering and/or sound clicking at 40 Hz (a technology called GENUS for Gamma Entrainment Using Sensory stimuli), reduces levels of amyloid-beta and tau proteins, prevents neuron death and preserves synapses and even sustains learning and memory in a variety of Alzheimer’s. This frequency is key to many other points of observations recently and through the past. We are seeing more and more elements where sound and light change the brain in material and repeatable ways. Link:

Brian Roemmele

150,608 views • 2 years ago