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#FluorescenceFriday #cellbiology #bioart Three examples of mitochondrial remodeling by lysosomes/late endosomes actively transported along microtubules, as seen by grazing incidence structured illumination microscopy at 1-2 frames/sec.

Eric Betzig

3,531 subscribers

23,085 просмотров • 2 лет назад •via X (Twitter)

Наука и технологии Образование Искусство #FluorescenceFriday #cellbiology #bioart

Anya Rossi• Live Now

Private livecam show

Комментарии: 3

Фото профиля Ewa Zarnowska 🦄 🧠 🔬

Ewa Zarnowska 🦄 🧠 🔬2 лет назад

Art

Фото профиля Evangelos Gatzogiannis

Evangelos Gatzogiannis2 лет назад

Grazing incidence SIM is a technique in my view that more people should use, would like to do it someday

Фото профиля Jess Heebner

Jess Heebner2 лет назад

These are so cool!!

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Actin filaments that drive amnioserosa cell shape changes during dorsal closure in Drosophila, (i.e., cytoskeletal contractions during fruit fly development) as seen by grazing incidence structured illumination microscopy:

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#FluorescenceFriday #cellbiology #microtubules 3/3 Growing MT tips tracked in 3D in relation to condensed chromosomes (orange) during different stages of mitosis, as seen by lattice light sheet microscopy

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Dictyostelia are FAST. Microtubules in clustering Dicty cells, color coded by height above the substrate, at 2 sec intervals for 1430 time points (~48 min). As seen by lattice light sheet microscopy:

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Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy

Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy

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#FluorescenceFriday #neuroscience #bioart A minute sliver of some of the most complex matter in the known universe: a small subset of neurons (yellow) and pre- (blue) and post- (magenta) synaptic markers over 75 x 100 x 125 um in layers IV-V of the mouse primary somatosensory cortex, as seen by combined expansion and lattice light sheet microscopy (ExLLSM): The first six seconds show all pre/post synaptic pairs, the remainder shows only those pairs associated with the small subset of labeled dendritic spines. An insanely complicated computational machine.

#FluorescenceFriday #neuroscience #bioart A minute sliver of some of the most complex matter in the known universe: a small subset of neurons (yellow) and pre- (blue) and post- (magenta) synaptic markers over 75 x 100 x 125 um in layers IV-V of the mouse primary somatosensory cortex, as seen by combined expansion and lattice light sheet microscopy (ExLLSM): The first six seconds show all pre/post synaptic pairs, the remainder shows only those pairs associated with the small subset of labeled dendritic spines. An insanely complicated computational machine.

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Leo Sayer : When I Need You" is a song written by Albert Hammond and Carole Bayer Sager. Its first appearance was as the title track of Hammond's 1976 album When I Need You. Leo Sayer's version, produced by Richard Perry, was a massive hit worldwide, reaching number 1 on the UK Singles Chart for three weeks in February 1977 after three of his earlier singles had stalled at number 2. It also reached number 1 on both the US Billboard Hot 100 for a single week in May 1977.

Leo Sayer : When I Need You" is a song written by Albert Hammond and Carole Bayer Sager. Its first appearance was as the title track of Hammond's 1976 album When I Need You. Leo Sayer's version, produced by Richard Perry, was a massive hit worldwide, reaching number 1 on the UK Singles Chart for three weeks in February 1977 after three of his earlier singles had stalled at number 2. It also reached number 1 on both the US Billboard Hot 100 for a single week in May 1977.

𝗧𝗶𝗺𝗲𝗹𝗲𝘀𝘀 𝗠𝘂𝘀𝗶𝗰 ✨🎵

11,850 просмотров • 4 месяцев назад

‼️🇺🇸: New angle shows Minnesota ICE AGENT was pushed by the vehicle which is when he appears to draw his firearm, but by the time he has his firearm and shoots she's already moving away. This was completely AVOIDABLE BY BOTH SIDES. 🤷🏻‍♂️ 2 things can be true at the same time: 1: DON'T IMPEDE LAW-ENFORCEMENT as they are working 2: ICE agents need better training, the agent SHOULD OF NEVER BEEN STANDING in FRONT OF an OPERATING VEHICLE at all, and he fired too late, he was clear imo. Sad day for our country! 🇺🇸

‼️🇺🇸: New angle shows Minnesota ICE AGENT was pushed by the vehicle which is when he appears to draw his firearm, but by the time he has his firearm and shoots she's already moving away. This was completely AVOIDABLE BY BOTH SIDES. 🤷🏻‍♂️ 2 things can be true at the same time: 1: DON'T IMPEDE LAW-ENFORCEMENT as they are working 2: ICE agents need better training, the agent SHOULD OF NEVER BEEN STANDING in FRONT OF an OPERATING VEHICLE at all, and he fired too late, he was clear imo. Sad day for our country! 🇺🇸

Diligent Denizen 🇺🇸

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🚨BREAKING: SEC CHARGES FLAMBOYANT HEX FOUNDER RICHARD HEART FOR MISAPPROPRIATING MILLIONS IN $1 BILLION CRYPTO RAISE The SEC has charged Richard Heart, the founder of one of Crypto's most controversial projects and the owner of a plethora of luxury goods, including the world's biggest diamond. BREAKDOWN OF CHARGES: 1) Conducting unregistered crypto asset security offerings The offering raised more than $1 billion in crypto assets from investors. Heart attempted to evade securities laws by asking investors to “sacrifice” crypto assets, instead of "invest" in exchange for PLS and PLSX tokens. 2) Misappropriation of funds The value of the misappropriation is approximately $12 million, the SEC stated. Heart allegedly called on investors to buy crypto asset securities in offerings that he failed to register. He then defrauded those investors by spending some of their crypto assets on exorbitant luxury goods, including sports cars, watches, and a 555-carat black diamond known as ‘The Enigma’. 3) Fraud in connection with the sale of the security The SEC claim Heart used a strategy known as “recycling” transactions, that enabled Heart to surreptitiously gain control of more Hex tokens. Heart and his co-conspirators had given the false impression of significant trading volumes and demand for Hex by using their own funds. The SEC estimates up to 97% of the investment volume was Heart and his accomplices’ funds. WHAT'S NEXT: The SEC is seeking injunctive relief, disgorgement of ill-gotten gains plus prejudgment interest, penalties, and other equitable relief. As you probably know by now, the SEC has a very high success rate in winning cases or reaching a settlement when they file charges. At the same time, unregistered token offerings have a history of settling with the SEC for a small amount of money. Remember the EOS settlement with the SEC of $24 million when they raised OVER $4 BILLION IN THEIR ICO? It's important to note that these SEC charges are all civil charges. The SEC cannot file criminal charges. Will the DOJ be next in filing criminal charges? WHAT’S YOUR OPINION OF HEX AND SEC ENFORCEMENT AGAINST CRYPTO?

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M.S. Barbano et al. (2010) investigated "the size, shape, position, pre-transport setting, and long-axis orientation of 175 boulders found along the south-eastern Ionian coast of Sicily. These megaclasts were deposited by the sea or moved from the same rocky coast to the shore platform and distributed within 60 m of the shoreline. Most boulders are rectangular to ellipsoidal, with sharp, broken edges. They are calcarenite fragments up to 27 t in mass."[1] Sicily detail: The ECDO State 1 to State 2 simulation detail is modelled over nine hours. The locations of the boulders are at (d) along the southeastern coast of Sicily. Orientation of the long axes of the boulders is visualised in the rose chart, closely matching the direction of flow seen in this region. Evidence of submarine cutting of the shelf can be seen southeast of the saddles in Calabria (a and b) and east of Sicily (c), where heavy flow may have been an agent of bench cutting along the flow axes (d) which aligns very closely with the ECDO moment of inertia for this location (12-13° west of north). Orange/red markers are marine fossil deposits. State 2 water levels are expected to have been higher than seen here as some returning water is lost from the simulation domain. [1] [2]

M.S. Barbano et al. (2010) investigated "the size, shape, position, pre-transport setting, and long-axis orientation of 175 boulders found along the south-eastern Ionian coast of Sicily. These megaclasts were deposited by the sea or moved from the same rocky coast to the shore platform and distributed within 60 m of the shoreline. Most boulders are rectangular to ellipsoidal, with sharp, broken edges. They are calcarenite fragments up to 27 t in mass."[1] Sicily detail: The ECDO State 1 to State 2 simulation detail is modelled over nine hours. The locations of the boulders are at (d) along the southeastern coast of Sicily. Orientation of the long axes of the boulders is visualised in the rose chart, closely matching the direction of flow seen in this region. Evidence of submarine cutting of the shelf can be seen southeast of the saddles in Calabria (a and b) and east of Sicily (c), where heavy flow may have been an agent of bench cutting along the flow axes (d) which aligns very closely with the ECDO moment of inertia for this location (12-13° west of north). Orange/red markers are marine fossil deposits. State 2 water levels are expected to have been higher than seen here as some returning water is lost from the simulation domain. [1] [2]

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Grateful Dead

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Full body late night hotel workout. Pull-ups, incline bench, lunges back to back 1-2 min rest. 15-30 reps. Finished off with a bit of jump rope at the end. I maintain this lean condition all year by eating 190-210g of protein a day, eating spinach/kale, controlling calories and LOTS of water. I'm 6'3" and fluctuate between 190-200lbs. I like combining strength with endurance when I train as this was how I trained when I rowed Division 1.

Full body late night hotel workout. Pull-ups, incline bench, lunges back to back 1-2 min rest. 15-30 reps. Finished off with a bit of jump rope at the end. I maintain this lean condition all year by eating 190-210g of protein a day, eating spinach/kale, controlling calories and LOTS of water. I'm 6'3" and fluctuate between 190-200lbs. I like combining strength with endurance when I train as this was how I trained when I rowed Division 1.

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There was heartbreak for the Three Lions in the World Cup semi-final after losing 2-1 to Argentina, ending their hopes of bringing football home for the first time since 1966. England took the early lead, but two late goals sent the South American side through. Prince William told the team to hold their heads high, but added he was gutted at the result. There was controversy after the game, as several of the Argentina players held up a flag given to them by their supporters that said "The Falklands Islands are Argentinian." #worldcup #football #england

There was heartbreak for the Three Lions in the World Cup semi-final after losing 2-1 to Argentina, ending their hopes of bringing football home for the first time since 1966. England took the early lead, but two late goals sent the South American side through. Prince William told the team to hold their heads high, but added he was gutted at the result. There was controversy after the game, as several of the Argentina players held up a flag given to them by their supporters that said "The Falklands Islands are Argentinian." #worldcup #football #england

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New Video 🎥 " $MMTLP: The Red Flags Ignored By The U.S. Securities and Exchange Commission". We know the SEC moves slow, but we also know that MMTLP has been on their radar since at least 2021! Is the SEC taking the investigation seriously? Have they noticed the links between FINRA, Ari Rubenstein & those that attempt to disparage the MMTLP Community? One, two, or even three of these links could've been written off as a coincidence, but 1 by 1, after doing some digging they all appear to lead back to Ari Rubenstein & his companies. Don't believe me? Just watch this short 10 minute video & see for yourself! FBI Los Angeles FBI Washington Field Criminal Division U.S. Department of Justice U.S. Secret Service DTCC Rep. Ralph Norman Senator Mike Crapo Dennis Kneale MARDÜK the META Guy😎🦋 #MMTLPFiasco

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Oliya Scootercaster 🛴

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Everything is going exactly as I predicted. The bear market is 53% done. Bitcoin has entered the final stage of the 2026 bear market. The cycle bottom is now approaching. $61K → $53K → $50K → $48k → $43K → $32K → $166K Scenario 1: → $48K in few days Scenario 2: → $32K by August Scenario 3: → $166K by january Remember, I've predicted every major move for 12 years. I was the only one publicly calling the exact bottom at ($16k) three years ago and the top at ($126k) in October. If you missed those calls, don’t worry. I’ll call the next one too. Turn notifications on.

Everything is going exactly as I predicted. The bear market is 53% done. Bitcoin has entered the final stage of the 2026 bear market. The cycle bottom is now approaching. $61K → $53K → $50K → $48k → $43K → $32K → $166K Scenario 1: → $48K in few days Scenario 2: → $32K by August Scenario 3: → $166K by january Remember, I've predicted every major move for 12 years. I was the only one publicly calling the exact bottom at ($16k) three years ago and the top at ($126k) in October. If you missed those calls, don’t worry. I’ll call the next one too. Turn notifications on.

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🔴 Gaza | December 24, 2025 Starting at dawn, Israeli warplanes have carried out airstrikes on southern Rafah, eastern Khan Younis, and the Al-Tuffah neighborhood east of Gaza City in the north, along with intense artillery fire on eastern areas of Al-Bureij refugee camp in central Gaza, Al Araby reports. At least one man was reported killed in Jabalia and three children were injured by the occupation’s bullets. Videos circulating from the north also show Israeli forces systematically demolishing homes in areas under their control. Al Araby cited sources who say Israel is actively expanding large-scale home demolition operations, particularly in Jabaliya, in northern Gaza. Since the so-called ceasefire began on October 11, Israel has killed at least 406 Palestinians and injured more than 1,100 others, the health ministry said yesterday. 🎥 Three children were injured after Israeli forces opened fire near the Jarin roundabout east of Jabalia, in the northern Gaza Strip, and were transported to a medical point for treatment. (Via Al Qastal)

Drop Site

56,571 просмотров • 7 месяцев назад

[Sweetness Lingers at Dawn] As the night fades and dawn arrives, let the cool touch of the ribbon, the warmth of breath by your ear, and Nerida's gentle caresses eternally extend the sweetness you've created together. "Adjutant, did you shiver just now? Was it my skin touching yours?" Go to YouTube >> 🎁 Follow our official account and share this post along with your UID and server. After the event ends at 2025/4/20 23:59 (UTC+8), 2 Adjutants will be randomly selected to each receive the following rewards: 1 Winner: Random Shikishi x1 1 Winner: Random Acrylic Stand x1 #Snowbreak

[Sweetness Lingers at Dawn] As the night fades and dawn arrives, let the cool touch of the ribbon, the warmth of breath by your ear, and Nerida's gentle caresses eternally extend the sweetness you've created together. "Adjutant, did you shiver just now? Was it my skin touching yours?" Go to YouTube >> 🎁 Follow our official account and share this post along with your UID and server. After the event ends at 2025/4/20 23:59 (UTC+8), 2 Adjutants will be randomly selected to each receive the following rewards: 1 Winner: Random Shikishi x1 1 Winner: Random Acrylic Stand x1 #Snowbreak

Snowbreak: Containment Zone

18,886 просмотров • 1 год назад