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#FluorescenceFriday #cellbiology #bioart Three examples of mitochondrial remodeling by lysosomes/late endosomes actively transported along microtubules, as seen by grazing incidence structured illumination microscopy at 1-2 frames/sec.

Eric Betzig

3,707 subscribers

23,102 次观看 • 2 年前 •via X (Twitter)

科学技术教育艺术 #FluorescenceFriday #cellbiology #bioart

Anya Rossi• Live Now

Private livecam show

3 条评论

Ewa Zarnowska 🦄 🧠 🔬 的头像

Ewa Zarnowska 🦄 🧠 🔬2 年前

Art

Evangelos Gatzogiannis 的头像

Evangelos Gatzogiannis2 年前

Grazing incidence SIM is a technique in my view that more people should use, would like to do it someday

Jess Heebner 的头像

Jess Heebner2 年前

These are so cool!!

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#FluorescenceFriday #cellbiology #bioart A neutrophilic cell migrating through a 3D collagen mesh at 1.3 sec intervals for 5.5 min, as seen by lattice light sheet microscopy.

#FluorescenceFriday #cellbiology #bioart A neutrophilic cell migrating through a 3D collagen mesh at 1.3 sec intervals for 5.5 min, as seen by lattice light sheet microscopy.

Eric Betzig

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Actin filaments that drive amnioserosa cell shape changes during dorsal closure in Drosophila, (i.e., cytoskeletal contractions during fruit fly development) as seen by grazing incidence structured illumination microscopy:

Actin filaments that drive amnioserosa cell shape changes during dorsal closure in Drosophila, (i.e., cytoskeletal contractions during fruit fly development) as seen by grazing incidence structured illumination microscopy:

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#FluorescenceFriday #cellbiology #microtubules 3/3 Growing MT tips tracked in 3D in relation to condensed chromosomes (orange) during different stages of mitosis, as seen by lattice light sheet microscopy

#FluorescenceFriday #cellbiology #microtubules 3/3 Growing MT tips tracked in 3D in relation to condensed chromosomes (orange) during different stages of mitosis, as seen by lattice light sheet microscopy

Eric Betzig

15,235 次观看 • 2 年前

Dictyostelia are FAST. Microtubules in clustering Dicty cells, color coded by height above the substrate, at 2 sec intervals for 1430 time points (~48 min). As seen by lattice light sheet microscopy:

Dictyostelia are FAST. Microtubules in clustering Dicty cells, color coded by height above the substrate, at 2 sec intervals for 1430 time points (~48 min). As seen by lattice light sheet microscopy:

Eric Betzig

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Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy

Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy

Eric Betzig

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#FluorescenceFriday #neuroscience #bioart A minute sliver of some of the most complex matter in the known universe: a small subset of neurons (yellow) and pre- (blue) and post- (magenta) synaptic markers over 75 x 100 x 125 um in layers IV-V of the mouse primary somatosensory cortex, as seen by combined expansion and lattice light sheet microscopy (ExLLSM): The first six seconds show all pre/post synaptic pairs, the remainder shows only those pairs associated with the small subset of labeled dendritic spines. An insanely complicated computational machine.

#FluorescenceFriday #neuroscience #bioart A minute sliver of some of the most complex matter in the known universe: a small subset of neurons (yellow) and pre- (blue) and post- (magenta) synaptic markers over 75 x 100 x 125 um in layers IV-V of the mouse primary somatosensory cortex, as seen by combined expansion and lattice light sheet microscopy (ExLLSM): The first six seconds show all pre/post synaptic pairs, the remainder shows only those pairs associated with the small subset of labeled dendritic spines. An insanely complicated computational machine.

Eric Betzig

17,476 次观看 • 2 年前

Leo Sayer : When I Need You" is a song written by Albert Hammond and Carole Bayer Sager. Its first appearance was as the title track of Hammond's 1976 album When I Need You. Leo Sayer's version, produced by Richard Perry, was a massive hit worldwide, reaching number 1 on the UK Singles Chart for three weeks in February 1977 after three of his earlier singles had stalled at number 2. It also reached number 1 on both the US Billboard Hot 100 for a single week in May 1977.

Leo Sayer : When I Need You" is a song written by Albert Hammond and Carole Bayer Sager. Its first appearance was as the title track of Hammond's 1976 album When I Need You. Leo Sayer's version, produced by Richard Perry, was a massive hit worldwide, reaching number 1 on the UK Singles Chart for three weeks in February 1977 after three of his earlier singles had stalled at number 2. It also reached number 1 on both the US Billboard Hot 100 for a single week in May 1977.

𝗧𝗶𝗺𝗲𝗹𝗲𝘀𝘀 𝗠𝘂𝘀𝗶𝗰 ✨🎵

11,850 次观看 • 5 个月前

‼️🇺🇸: New angle shows Minnesota ICE AGENT was pushed by the vehicle which is when he appears to draw his firearm, but by the time he has his firearm and shoots she's already moving away. This was completely AVOIDABLE BY BOTH SIDES. 🤷🏻‍♂️ 2 things can be true at the same time: 1: DON'T IMPEDE LAW-ENFORCEMENT as they are working 2: ICE agents need better training, the agent SHOULD OF NEVER BEEN STANDING in FRONT OF an OPERATING VEHICLE at all, and he fired too late, he was clear imo. Sad day for our country! 🇺🇸

‼️🇺🇸: New angle shows Minnesota ICE AGENT was pushed by the vehicle which is when he appears to draw his firearm, but by the time he has his firearm and shoots she's already moving away. This was completely AVOIDABLE BY BOTH SIDES. 🤷🏻‍♂️ 2 things can be true at the same time: 1: DON'T IMPEDE LAW-ENFORCEMENT as they are working 2: ICE agents need better training, the agent SHOULD OF NEVER BEEN STANDING in FRONT OF an OPERATING VEHICLE at all, and he fired too late, he was clear imo. Sad day for our country! 🇺🇸

Diligent Denizen 🇺🇸

22,558 次观看 • 7 个月前

🚨BREAKING: SEC CHARGES FLAMBOYANT HEX FOUNDER RICHARD HEART FOR MISAPPROPRIATING MILLIONS IN $1 BILLION CRYPTO RAISE The SEC has charged Richard Heart, the founder of one of Crypto's most controversial projects and the owner of a plethora of luxury goods, including the world's biggest diamond. BREAKDOWN OF CHARGES: 1) Conducting unregistered crypto asset security offerings The offering raised more than $1 billion in crypto assets from investors. Heart attempted to evade securities laws by asking investors to “sacrifice” crypto assets, instead of "invest" in exchange for PLS and PLSX tokens. 2) Misappropriation of funds The value of the misappropriation is approximately $12 million, the SEC stated. Heart allegedly called on investors to buy crypto asset securities in offerings that he failed to register. He then defrauded those investors by spending some of their crypto assets on exorbitant luxury goods, including sports cars, watches, and a 555-carat black diamond known as ‘The Enigma’. 3) Fraud in connection with the sale of the security The SEC claim Heart used a strategy known as “recycling” transactions, that enabled Heart to surreptitiously gain control of more Hex tokens. Heart and his co-conspirators had given the false impression of significant trading volumes and demand for Hex by using their own funds. The SEC estimates up to 97% of the investment volume was Heart and his accomplices’ funds. WHAT'S NEXT: The SEC is seeking injunctive relief, disgorgement of ill-gotten gains plus prejudgment interest, penalties, and other equitable relief. As you probably know by now, the SEC has a very high success rate in winning cases or reaching a settlement when they file charges. At the same time, unregistered token offerings have a history of settling with the SEC for a small amount of money. Remember the EOS settlement with the SEC of $24 million when they raised OVER $4 BILLION IN THEIR ICO? It's important to note that these SEC charges are all civil charges. The SEC cannot file criminal charges. Will the DOJ be next in filing criminal charges? WHAT’S YOUR OPINION OF HEX AND SEC ENFORCEMENT AGAINST CRYPTO?

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Left: President Trump, "Everyone's seen it. Renee Nicole Good was very violent. She's a very radical person" Right: Renee Nicole Good, "That's fine dude, I'm not mad at you. I'm not mad at you" Your reminder with three clips showing the murder of Renee Nicole Good: Clip 1: You can see Renee Nicole Good wave three times to the ICE cars to go past. One of them did, the second one chose to stop Clip 2: When the second ICE car stopped, Renee Nicole Good with her car window open, shouts to ICE "I'm pulling out" Clip 3: As she's pulling out, not driving into anybody, she's murdered by ICE

Farrukh

104,135 次观看 • 7 个月前

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Tom Lee sees the memory trade having a new cycle & not slowing down anytime soon… $DRAM is seen as being buyable with the dips & pullbacks … However, $DISK by Tema ETFs (in partnership with SemiAnalysis) could be a better memory ETF that is: 1) More Diversified than DRAM by RoundHill 2) Higher concentration NAND 3) Actively managed by a semiconductor-focused team in SemiAnalysis If $DRAM is a $200 ETF … Then $DISK is a $150 ETF… Robots, Humanoids, & autonomous cars need memory… You can’t call the end of the cycle…. I’d also argue that Sandisk $SNDK deserves an overweight position in a memory ETF like DISK.

Marcos Milla

151,633 次观看 • 1 个月前

M.S. Barbano et al. (2010) investigated "the size, shape, position, pre-transport setting, and long-axis orientation of 175 boulders found along the south-eastern Ionian coast of Sicily. These megaclasts were deposited by the sea or moved from the same rocky coast to the shore platform and distributed within 60 m of the shoreline. Most boulders are rectangular to ellipsoidal, with sharp, broken edges. They are calcarenite fragments up to 27 t in mass."[1] Sicily detail: The ECDO State 1 to State 2 simulation detail is modelled over nine hours. The locations of the boulders are at (d) along the southeastern coast of Sicily. Orientation of the long axes of the boulders is visualised in the rose chart, closely matching the direction of flow seen in this region. Evidence of submarine cutting of the shelf can be seen southeast of the saddles in Calabria (a and b) and east of Sicily (c), where heavy flow may have been an agent of bench cutting along the flow axes (d) which aligns very closely with the ECDO moment of inertia for this location (12-13° west of north). Orange/red markers are marine fossil deposits. State 2 water levels are expected to have been higher than seen here as some returning water is lost from the simulation domain. [1] [2]

M.S. Barbano et al. (2010) investigated "the size, shape, position, pre-transport setting, and long-axis orientation of 175 boulders found along the south-eastern Ionian coast of Sicily. These megaclasts were deposited by the sea or moved from the same rocky coast to the shore platform and distributed within 60 m of the shoreline. Most boulders are rectangular to ellipsoidal, with sharp, broken edges. They are calcarenite fragments up to 27 t in mass."[1] Sicily detail: The ECDO State 1 to State 2 simulation detail is modelled over nine hours. The locations of the boulders are at (d) along the southeastern coast of Sicily. Orientation of the long axes of the boulders is visualised in the rose chart, closely matching the direction of flow seen in this region. Evidence of submarine cutting of the shelf can be seen southeast of the saddles in Calabria (a and b) and east of Sicily (c), where heavy flow may have been an agent of bench cutting along the flow axes (d) which aligns very closely with the ECDO moment of inertia for this location (12-13° west of north). Orange/red markers are marine fossil deposits. State 2 water levels are expected to have been higher than seen here as some returning water is lost from the simulation domain. [1] [2]

Craig Stone

28,110 次观看 • 9 个月前

Dave's Picks Vol. 57: Uptown Theatre, Chicago, Il (2/1/78) is here ⚡️ The first complete unreleased show in the 2026 Dave's Picks series exhibits countless examples of the very best of both 1977 and 1978, bridging two distinct yet complementary eras of the Grateful Dead’s music. This very first Dead run at the Uptown is infused with bold exploration, from the monster first set of classics and the second set that ventures from Bobby's powerful delivery of "Samson and Delilah," to the Rhythm Devils' spacey psychedelic improvisations beyond "Drums>Space,” and Jerry's over-the-top notes filling in every nook and cranny. As an added bonus, the 2nd set from 1/31/78 is laid out on this one as well. Recorded by Betty Cantor-Jackson and mastered to HDCD specs by Jeffrey Norman at Mockingbird Mastering, Dave's Picks Vol. 57: Uptown Theatre, Chicago, Il (2/1/78) can be found here:

Dave's Picks Vol. 57: Uptown Theatre, Chicago, Il (2/1/78) is here ⚡️ The first complete unreleased show in the 2026 Dave's Picks series exhibits countless examples of the very best of both 1977 and 1978, bridging two distinct yet complementary eras of the Grateful Dead’s music. This very first Dead run at the Uptown is infused with bold exploration, from the monster first set of classics and the second set that ventures from Bobby's powerful delivery of "Samson and Delilah," to the Rhythm Devils' spacey psychedelic improvisations beyond "Drums>Space,” and Jerry's over-the-top notes filling in every nook and cranny. As an added bonus, the 2nd set from 1/31/78 is laid out on this one as well. Recorded by Betty Cantor-Jackson and mastered to HDCD specs by Jeffrey Norman at Mockingbird Mastering, Dave's Picks Vol. 57: Uptown Theatre, Chicago, Il (2/1/78) can be found here:

Grateful Dead

29,466 次观看 • 6 个月前

Full body late night hotel workout. Pull-ups, incline bench, lunges back to back 1-2 min rest. 15-30 reps. Finished off with a bit of jump rope at the end. I maintain this lean condition all year by eating 190-210g of protein a day, eating spinach/kale, controlling calories and LOTS of water. I'm 6'3" and fluctuate between 190-200lbs. I like combining strength with endurance when I train as this was how I trained when I rowed Division 1.

Full body late night hotel workout. Pull-ups, incline bench, lunges back to back 1-2 min rest. 15-30 reps. Finished off with a bit of jump rope at the end. I maintain this lean condition all year by eating 190-210g of protein a day, eating spinach/kale, controlling calories and LOTS of water. I'm 6'3" and fluctuate between 190-200lbs. I like combining strength with endurance when I train as this was how I trained when I rowed Division 1.

Myron Gaines

256,054 次观看 • 2 年前

There was heartbreak for the Three Lions in the World Cup semi-final after losing 2-1 to Argentina, ending their hopes of bringing football home for the first time since 1966. England took the early lead, but two late goals sent the South American side through. Prince William told the team to hold their heads high, but added he was gutted at the result. There was controversy after the game, as several of the Argentina players held up a flag given to them by their supporters that said "The Falklands Islands are Argentinian." #worldcup #football #england

There was heartbreak for the Three Lions in the World Cup semi-final after losing 2-1 to Argentina, ending their hopes of bringing football home for the first time since 1966. England took the early lead, but two late goals sent the South American side through. Prince William told the team to hold their heads high, but added he was gutted at the result. There was controversy after the game, as several of the Argentina players held up a flag given to them by their supporters that said "The Falklands Islands are Argentinian." #worldcup #football #england

Good Morning Britain

11,882 次观看 • 29 天前

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New Video 🎥 " $MMTLP: The Red Flags Ignored By The U.S. Securities and Exchange Commission". We know the SEC moves slow, but we also know that MMTLP has been on their radar since at least 2021! Is the SEC taking the investigation seriously? Have they noticed the links between FINRA, Ari Rubenstein & those that attempt to disparage the MMTLP Community? One, two, or even three of these links could've been written off as a coincidence, but 1 by 1, after doing some digging they all appear to lead back to Ari Rubenstein & his companies. Don't believe me? Just watch this short 10 minute video & see for yourself! FBI Los Angeles FBI Washington Field Criminal Division U.S. Department of Justice U.S. Secret Service DTCC Rep. Ralph Norman Senator Mike Crapo Dennis Kneale MARDÜK the META Guy😎🦋 #MMTLPFiasco

Rare DD

192,450 次观看 • 2 年前

BREAKING: Teen Opens Fire in Times Square After Clash With Group, Three Injured Including Bystander Three people were injured early Saturday morning when a 17-year-old gunman opened fire in Times Square, according to police. The shooting occurred around 1:20 a.m. near the intersection of West 44th Street and 7th Avenue, following what authorities described as a verbal dispute between two individuals. An 18-year-old woman was grazed in the neck, while a 19-year-old man and a 65-year-old man sustained gunshot wounds to the legs. All three victims were transported by EMS to Bellevue Hospital and are listed in stable condition. Police said the 17-year-old suspect was arrested at the scene, and a firearm was recovered. His identity has not been released due to his age, and charges had not yet been filed as of Saturday morning. Witnesses described chaotic scenes as crowds scattered from the area outside the Hard Rock Cafe when the shots were fired. One witness told that the suspect had been surrounded by a group of teens before producing a gun and firing. The 65-year-old victim was described by the witness as possibly a bystander, while the aggressors were said to be young. Video by Dakota Santiago FreedomNews.Tv FNTV Desk@freedomnews.tv to license

BREAKING: Teen Opens Fire in Times Square After Clash With Group, Three Injured Including Bystander Three people were injured early Saturday morning when a 17-year-old gunman opened fire in Times Square, according to police. The shooting occurred around 1:20 a.m. near the intersection of West 44th Street and 7th Avenue, following what authorities described as a verbal dispute between two individuals. An 18-year-old woman was grazed in the neck, while a 19-year-old man and a 65-year-old man sustained gunshot wounds to the legs. All three victims were transported by EMS to Bellevue Hospital and are listed in stable condition. Police said the 17-year-old suspect was arrested at the scene, and a firearm was recovered. His identity has not been released due to his age, and charges had not yet been filed as of Saturday morning. Witnesses described chaotic scenes as crowds scattered from the area outside the Hard Rock Cafe when the shots were fired. One witness told that the suspect had been surrounded by a group of teens before producing a gun and firing. The 65-year-old victim was described by the witness as possibly a bystander, while the aggressors were said to be young. Video by Dakota Santiago FreedomNews.Tv FNTV [email protected] to license

Oliya Scootercaster 🛴

24,793 次观看 • 1 年前

Everything is going exactly as I predicted. The bear market is 53% done. Bitcoin has entered the final stage of the 2026 bear market. The cycle bottom is now approaching. $61K → $53K → $50K → $48k → $43K → $32K → $166K Scenario 1: → $48K in few days Scenario 2: → $32K by August Scenario 3: → $166K by january Remember, I've predicted every major move for 12 years. I was the only one publicly calling the exact bottom at ($16k) three years ago and the top at ($126k) in October. If you missed those calls, don’t worry. I’ll call the next one too. Turn notifications on.

Everything is going exactly as I predicted. The bear market is 53% done. Bitcoin has entered the final stage of the 2026 bear market. The cycle bottom is now approaching. $61K → $53K → $50K → $48k → $43K → $32K → $166K Scenario 1: → $48K in few days Scenario 2: → $32K by August Scenario 3: → $166K by january Remember, I've predicted every major move for 12 years. I was the only one publicly calling the exact bottom at ($16k) three years ago and the top at ($126k) in October. If you missed those calls, don’t worry. I’ll call the next one too. Turn notifications on.

Crypto Lens

51,273 次观看 • 2 个月前

[Sweetness Lingers at Dawn] As the night fades and dawn arrives, let the cool touch of the ribbon, the warmth of breath by your ear, and Nerida's gentle caresses eternally extend the sweetness you've created together. "Adjutant, did you shiver just now? Was it my skin touching yours?" Go to YouTube >> 🎁 Follow our official account and share this post along with your UID and server. After the event ends at 2025/4/20 23:59 (UTC+8), 2 Adjutants will be randomly selected to each receive the following rewards: 1 Winner: Random Shikishi x1 1 Winner: Random Acrylic Stand x1 #Snowbreak

[Sweetness Lingers at Dawn] As the night fades and dawn arrives, let the cool touch of the ribbon, the warmth of breath by your ear, and Nerida's gentle caresses eternally extend the sweetness you've created together. "Adjutant, did you shiver just now? Was it my skin touching yours?" Go to YouTube >> 🎁 Follow our official account and share this post along with your UID and server. After the event ends at 2025/4/20 23:59 (UTC+8), 2 Adjutants will be randomly selected to each receive the following rewards: 1 Winner: Random Shikishi x1 1 Winner: Random Acrylic Stand x1 #Snowbreak

Snowbreak: Containment Zone

18,886 次观看 • 1 年前