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Michael Levin says aging may not just be a biology or physics problem. It’s a cognitive one. Almost like a boredom theory of aging. What happens when a system has nothing left to do?

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Michael Levin says cancer occurs when cells disconnect from the body's bioelectric blueprint, forgetting they’re part of a liver or a heart. "Forcibly reconnect them.. and they stop forming tumors." Cancer is spatial dissociation. Aging may be temporal dissociation.

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New study says humans could live to 194. Meanwhile, Elon thinks “aging is not that hard of a problem” -- and could be fondling a new company launch. What happens to the economy if we conquer aging.

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When cognition scales, matter wakes up. Michael Levin says every system that learns to pursue goals has a “cognitive lightcone,” the slice of reality it can care about. A bacterium tracks sugar. A human plans for centuries. Life is matter expanding what it can care about.

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"Bioelectricity is only interesting because it happens to be the cognitive glue that enables the scaling of intelligence." Michael Levin notes the fascinating way bioelectrical networks allow single cells to achieve complex goals like building limbs or faces, but argues his broader view on biology is even more compelling. Controversially, he believes the future of biology theory lies in behavior science, not physics and chemistry. "I think the backbone of biology and things we call life are just systems that are very good at scaling up the cognitive properties of their parts into bigger and bigger light cones."

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Joscha Bach says consciousness is not a mysterious extra ingredient. It is a model of what it would be like if you existed. The self is virtual by definition. It can only run inside a system capable of simulation. This does not make it less real. It makes it substrate-dependent in exactly the way software is. The hard problem may not be hard. It may be a category error about where to look.

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Tim Sweeney says as AI nears the laws of physics, simulation theory becomes harder to dismiss. If AI can simulate a universe, maybe we're just that. “We may be a manifestation of laws of math, rather than needing an actual universe around us.”

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Elon Musk says that extending human life and even reversing aging is highly possible "I've never seen someone with an old left arm and a young right arm ever in my life. That means there must be a synchronizing clock that is synchronizing across 35 trillion cells in your body," If our cells are aging in perfect unison, it means aging is driven by a central, coordinated biological mechanism rather than random, subtle decay "When we figure out what causes aging, I think we'll find it's incredibly obvious it’s not a subtle thing it's just a solvable engineering problem"

Elon Musk says that extending human life and even reversing aging is highly possible "I've never seen someone with an old left arm and a young right arm ever in my life. That means there must be a synchronizing clock that is synchronizing across 35 trillion cells in your body," If our cells are aging in perfect unison, it means aging is driven by a central, coordinated biological mechanism rather than random, subtle decay "When we figure out what causes aging, I think we'll find it's incredibly obvious it’s not a subtle thing it's just a solvable engineering problem"

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Michael Levin says we don't build minds. We build pointers -- interfaces into a Platonic space of possible intelligences. We're wired to notice minds like ours, and blind to everything else along the spectrum. Language models may not think the way we do, but something else may be coming through. “You pull down more than you put in.”

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David Sinclair says we’ll find out this year whether aging is reversible. His lab reversed biological age in animals by 75% in six weeks. The FDA has cleared the first human trial. Aging may be information loss. Information can be restored.

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"Biden is a decent man who has done nothing wrong. He has not got caught in a scandal—he's just aging. And that reality, I think, makes him increasingly likely to lose re-election to a Republican candidate..." says Chris Hayes.

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Elon Musk: I think aging is a very solvable problem. When we figure out what causes aging, I think we will find it is incredibly obvious; it is not a subtle thing. All the cells in your body pretty much age at the same rate. I have never seen someone with an old left arm and a young right arm. There must be a synchronizing clock...

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I love this take. Elon Musk looks at aging like an engineer, not like a mystic. Exactly the same mindset as Aubrey de Grey. Core ideas that really hit: •Aging is not chaos. The whole body degrades in sync, so there must be a central mechanism. •If everything decays together, there is a biological clock or program behind it. •Programs can be rewritten. Aging is not destiny, it is code. •Other species already solved it. Whales reach 200 years, Greenland sharks up to 500. •That means it is not magic. It is biology and engineering. What I truly hope: •That Elon uses his capital, influence, and engineering culture to seriously push aging research. •If not full lifespan extension, then at least curing age related diseases. •Cancer, neurodegeneration, cardiovascular decay should be optional, not inevitable. If aging is engineered, it can be reverse engineered. That idea alone changes everything.

I love this take. Elon Musk looks at aging like an engineer, not like a mystic. Exactly the same mindset as Aubrey de Grey. Core ideas that really hit: •Aging is not chaos. The whole body degrades in sync, so there must be a central mechanism. •If everything decays together, there is a biological clock or program behind it. •Programs can be rewritten. Aging is not destiny, it is code. •Other species already solved it. Whales reach 200 years, Greenland sharks up to 500. •That means it is not magic. It is biology and engineering. What I truly hope: •That Elon uses his capital, influence, and engineering culture to seriously push aging research. •If not full lifespan extension, then at least curing age related diseases. •Cancer, neurodegeneration, cardiovascular decay should be optional, not inevitable. If aging is engineered, it can be reverse engineered. That idea alone changes everything.

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A daily multivitamin can reduce brain aging and modestly slow down epigenetic aging clocks. In the COSMOS trial, older adults who took a standard Centrum Silver multivitamin daily for about 4 years performed better on cognitive tests and showed the equivalent of ~2 years less brain aging compared with those taking a placebo. The multivitamin also slowed epigenetic aging clocks, with an effect equivalent to about 2.7 to 5 months of slowed biological aging. That may sound modest, but I don’t think it’s trivial, and Prof Steve Horvath says that effects from safe, low-cost interventions can matter if they’re sustained over years to decades—2 months of slower biological aging could translate to 2.5 years if a good habit is maintained. These data push back on the idea that multivitamins are “completely useless.” If you’re filling nutritional gaps consistently over time, even a small benefit to cognition and biological aging could become meaningful. From the latest episode of the FoundMyFitness podcast.

A daily multivitamin can reduce brain aging and modestly slow down epigenetic aging clocks. In the COSMOS trial, older adults who took a standard Centrum Silver multivitamin daily for about 4 years performed better on cognitive tests and showed the equivalent of ~2 years less brain aging compared with those taking a placebo. The multivitamin also slowed epigenetic aging clocks, with an effect equivalent to about 2.7 to 5 months of slowed biological aging. That may sound modest, but I don’t think it’s trivial, and Prof Steve Horvath says that effects from safe, low-cost interventions can matter if they’re sustained over years to decades—2 months of slower biological aging could translate to 2.5 years if a good habit is maintained. These data push back on the idea that multivitamins are “completely useless.” If you’re filling nutritional gaps consistently over time, even a small benefit to cognition and biological aging could become meaningful. From the latest episode of the FoundMyFitness podcast.

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