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David Sinclair says we’ll find out this year whether aging is reversible. His lab reversed biological age in animals by 75% in six weeks. The FDA has cleared the first human trial. Aging may be information loss. Information can be restored.

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🚨Dr. David Sinclair's, lab reversed biological age in animals by 50 to 75% in six weeks The FDA has just cleared the first human trial for next month. He describes the human body as a computer that can be rebooted.

🚨Dr. David Sinclair's, lab reversed biological age in animals by 50 to 75% in six weeks The FDA has just cleared the first human trial for next month. He describes the human body as a computer that can be rebooted.

Skywatch Signal

772,131 просмотров • 6 месяцев назад

If this holds up, it is absolutely mind blowing. 🤯 Reversing biological age by 50 to 75 percent in animals in weeks and now a first human trial cleared. We might be watching the first real crack in the concept of aging as inevitable.

If this holds up, it is absolutely mind blowing. 🤯 Reversing biological age by 50 to 75 percent in animals in weeks and now a first human trial cleared. We might be watching the first real crack in the concept of aging as inevitable.

VraserX e/acc

53,230 просмотров • 6 месяцев назад

🚨BREAKING: Scientists Just Reversed Aging by UP TO 75% in Animals in ONLY 6 WEEKS... and Humans Are NEXT MONTH! Harvard genius Dr. David Sinclair's lab turned old animals YOUNG again, like hitting Ctrl+Z on biology. He calls your body a glitchy computer that can be FULLY REBOOTED. FDA just gave the green light for the first human trial... starting NEXT MONTH. Immortality just got a launch date? You aging backwards soon? #AgeReversal #Longevity #Immortality

🚨BREAKING: Scientists Just Reversed Aging by UP TO 75% in Animals in ONLY 6 WEEKS... and Humans Are NEXT MONTH! Harvard genius Dr. David Sinclair's lab turned old animals YOUNG again, like hitting Ctrl+Z on biology. He calls your body a glitchy computer that can be FULLY REBOOTED. FDA just gave the green light for the first human trial... starting NEXT MONTH. Immortality just got a launch date? You aging backwards soon? #AgeReversal #Longevity #Immortality

ᙢinus ᙡells

83,889 просмотров • 6 месяцев назад

David Sinclair said: "You can reverse aging by 75% in 6 weeks… by reinstalling the "software" of the body so that it's young again." This idea sprouted when he proved in his first experiment that you can accelerate aging in mice: "We took two mice born on the same day—same age, same genetics. We 'scratched the CD' of one mouse, corrupting its software and accelerating its aging. The result was dramatic. One looked far older than its brother." He believed if you can give aging, you can also take it away. Tomorrow, I'll share his experiment on how he reversed aging in mice (and then Monkeys). — David Sinclair

David Sinclair said: "You can reverse aging by 75% in 6 weeks… by reinstalling the "software" of the body so that it's young again." This idea sprouted when he proved in his first experiment that you can accelerate aging in mice: "We took two mice born on the same day—same age, same genetics. We 'scratched the CD' of one mouse, corrupting its software and accelerating its aging. The result was dramatic. One looked far older than its brother." He believed if you can give aging, you can also take it away. Tomorrow, I'll share his experiment on how he reversed aging in mice (and then Monkeys). — David Sinclair

Goku

985,946 просмотров • 5 месяцев назад

David Sinclair said: "You can reverse aging by 75% in 6 weeks… by reinstalling the "software" of the body so that it's young again." This idea sprouted when he proved in his first experiment that you can accelerate aging in mice: "We took two mice born on the same day—same age, same genetics. We "scratched the CD" of one mouse, corrupting its software and accelerating its aging. The result was dramatic. One looked far older than its brother." He believed if you can give aging, you can also take it away. Tomorrow, I'll share his experiment on how he reversed aging in mice (and then Monkeys). — David Sinclair

David Sinclair said: "You can reverse aging by 75% in 6 weeks… by reinstalling the "software" of the body so that it's young again." This idea sprouted when he proved in his first experiment that you can accelerate aging in mice: "We took two mice born on the same day—same age, same genetics. We "scratched the CD" of one mouse, corrupting its software and accelerating its aging. The result was dramatic. One looked far older than its brother." He believed if you can give aging, you can also take it away. Tomorrow, I'll share his experiment on how he reversed aging in mice (and then Monkeys). — David Sinclair

John Cumbers

417,802 просмотров • 5 месяцев назад

Dr. David Sinclair says his lab at Harvard grew a miniature human brain in a dish. Then two small black dots appeared on its surface. They were eyes. These brains are grown from single human cells. They develop the same structures found in a full human brain... They even have measurable brain waves... And under a microscope, you can see calcium signals firing like fireworks. This indicates neurons are communicating with each other in the same way neurons in your brain are firing right now as you read this. After about a year, the firing fades and the brain loses function. Sinclair says when his team treats these aging brains with three "longevity" genes called OSK, the firing comes back on. They have also introduced Alzheimer's disease into these brains. Using the same three genes, it reverses. He says this technology is not limited to brains. His lab has reversed aging in the eye, liver, kidney, and skin. Every tissue responds to the same treatment. Now the first human trial is coming. — David Sinclair (David Sinclair) on Tom Bilyeu's (Tom Bilyeu) podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. Tickets available in the comments below.

Dr. David Sinclair says his lab at Harvard grew a miniature human brain in a dish. Then two small black dots appeared on its surface. They were eyes. These brains are grown from single human cells. They develop the same structures found in a full human brain... They even have measurable brain waves... And under a microscope, you can see calcium signals firing like fireworks. This indicates neurons are communicating with each other in the same way neurons in your brain are firing right now as you read this. After about a year, the firing fades and the brain loses function. Sinclair says when his team treats these aging brains with three "longevity" genes called OSK, the firing comes back on. They have also introduced Alzheimer's disease into these brains. Using the same three genes, it reverses. He says this technology is not limited to brains. His lab has reversed aging in the eye, liver, kidney, and skin. Every tissue responds to the same treatment. Now the first human trial is coming. — David Sinclair (David Sinclair) on Tom Bilyeu's (Tom Bilyeu) podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. Tickets available in the comments below.

John Cumbers

157,742 просмотров • 4 месяцев назад

🚨David Sinclair: “The first potential human age-reversal technology is in people right now.” ROGAN: “What is the current state of science as applied to longevity treatments?” SINCLAIR: “We have a human clinical trial.” ROGAN: “If people get old and we understand the mechanism, why couldn’t we reverse it?” SINCLAIR: “My colleagues and I found that aging has a root cause that’s the same in pretty much every cell in the body, and that we could control that.” “In 2020, we had a big publication that showed we could actually safely, for the first time, reverse that process, like reinstalling software in the cell to make it work again.” ---- The treatment is ER-100, an experimental epigenetic reprogramming gene therapy being developed by Life Biosciences, a company co-founded by Harvard geneticist Dr. David Sinclair. In the current FDA clinical trial, the therapy is delivered by injection into the eye. If this works in humans, it could be a major step toward actually reversing aspects of biological aging rather than simply slowing them down. Joe Rogan David Sinclair

🚨David Sinclair: “The first potential human age-reversal technology is in people right now.” ROGAN: “What is the current state of science as applied to longevity treatments?” SINCLAIR: “We have a human clinical trial.” ROGAN: “If people get old and we understand the mechanism, why couldn’t we reverse it?” SINCLAIR: “My colleagues and I found that aging has a root cause that’s the same in pretty much every cell in the body, and that we could control that.” “In 2020, we had a big publication that showed we could actually safely, for the first time, reverse that process, like reinstalling software in the cell to make it work again.” ---- The treatment is ER-100, an experimental epigenetic reprogramming gene therapy being developed by Life Biosciences, a company co-founded by Harvard geneticist Dr. David Sinclair. In the current FDA clinical trial, the therapy is delivered by injection into the eye. If this works in humans, it could be a major step toward actually reversing aspects of biological aging rather than simply slowing them down. Joe Rogan David Sinclair

KanekoaTheGreat

1,232,850 просмотров • 27 дней назад

David Sinclair says the first person to live to 150 is a teenager who's alive today. He's taken flak from colleagues for years over this prediction. He doesn't care. He still stands by it. "The first person to live to 150 has already been born." Here's why: A 14-year-old today has 80+ years of exponential technological progress ahead of them. Just look at what's happened in the last 10 years: • His lab reversed aging in monkey eyes by 95% • AI now does in 2 months what would have taken thousands of years. • His team has oral molecules that made old mice young again in 4 weeks • The first human age-reversal trial begins in January And that's just the beginning. There'll be more advancements in major medical technologies and therapies soon, including in: • Gene therapy • AI-designed drugs • Whole-body rejuvenation • Epigenetic reprogramming All of it will arrive within a teenager's lifetime. Sinclair believes this is a realistic projection of where the science is heading. Sinclair's advice for everyone is to stay healthy long enough to intercept what's coming. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

David Sinclair says the first person to live to 150 is a teenager who's alive today. He's taken flak from colleagues for years over this prediction. He doesn't care. He still stands by it. "The first person to live to 150 has already been born." Here's why: A 14-year-old today has 80+ years of exponential technological progress ahead of them. Just look at what's happened in the last 10 years: • His lab reversed aging in monkey eyes by 95% • AI now does in 2 months what would have taken thousands of years. • His team has oral molecules that made old mice young again in 4 weeks • The first human age-reversal trial begins in January And that's just the beginning. There'll be more advancements in major medical technologies and therapies soon, including in: • Gene therapy • AI-designed drugs • Whole-body rejuvenation • Epigenetic reprogramming All of it will arrive within a teenager's lifetime. Sinclair believes this is a realistic projection of where the science is heading. Sinclair's advice for everyone is to stay healthy long enough to intercept what's coming. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

John Cumbers

84,263 просмотров • 4 месяцев назад

Dr. David Sinclair, a Harvard aging researcher, tested his own biological age and got a number that terrified him. At 48, his blood test came back reading 58. Ten years older than he actually was. He started metformin first. His age barely moved, down to 56. Then he began taking an NAD-boosting molecule his lab had been testing in mice, the same one that reversed mitochondrial aging in old animals within a week. Months later, he retested. His biological age had dropped to 31.4. He wasn't just younger than before. He was younger than his real age by nearly two decades. His nurse called his latest labs "better than perfect." — Dr. David Sinclair on Dr. Mark Hyman's (@markhymanmd) podcast

Dr. David Sinclair, a Harvard aging researcher, tested his own biological age and got a number that terrified him. At 48, his blood test came back reading 58. Ten years older than he actually was. He started metformin first. His age barely moved, down to 56. Then he began taking an NAD-boosting molecule his lab had been testing in mice, the same one that reversed mitochondrial aging in old animals within a week. Months later, he retested. His biological age had dropped to 31.4. He wasn't just younger than before. He was younger than his real age by nearly two decades. His nurse called his latest labs "better than perfect." — Dr. David Sinclair on Dr. Mark Hyman's (@markhymanmd) podcast

Goku

43,842 просмотров • 12 дней назад

Dr. David Sinclair said something to Prof Andrew Huberman that left me thinking... "Your cells are forgetting who they are." That is not a metaphor. That is the biological mechanism behind aging itself. Dr. David Sinclair then explained how it works... Every cell in your body carries the same DNA. A nerve cell and a skin cell are genetically identical. What makes them different is which genes are switched on and which are kept silent. That system of switches is called the epigenome. Think of DNA as a music library. The epigenome is the playlist. Each cell plays a specific set of songs. As long as every cell plays the right playlist, the body works perfectly. Aging is what happens when the playlists get corrupted. Genes that should stay silent start activating in the wrong cells. The cell loses its identity. It forgets what it was built to do. And according to Dr. David Sinclair, that single process is the root cause of heart disease, Alzheimer's, and most cancers. Not separate problems. The same problem, showing up in different places. The part that stopped me cold was what comes after that. If aging is information loss, it can be reversed by restoring the information. Dr. David Sinclair's lab has already done this in animals. When they restored the epigenetic signals, the cells remembered what they were. The aging reversed. Huberman asked whether the diseases go away too. Dr. David Sinclair did not hedge. " If you turn the clock back in tissues, those diseases go away." Every generation inherits assumptions about what the body can and cannot do. This one just changed. Follow @YourDocGoku for the science rewriting what we thought was permanent. David Sinclair

Dr. David Sinclair said something to Prof Andrew Huberman that left me thinking... "Your cells are forgetting who they are." That is not a metaphor. That is the biological mechanism behind aging itself. Dr. David Sinclair then explained how it works... Every cell in your body carries the same DNA. A nerve cell and a skin cell are genetically identical. What makes them different is which genes are switched on and which are kept silent. That system of switches is called the epigenome. Think of DNA as a music library. The epigenome is the playlist. Each cell plays a specific set of songs. As long as every cell plays the right playlist, the body works perfectly. Aging is what happens when the playlists get corrupted. Genes that should stay silent start activating in the wrong cells. The cell loses its identity. It forgets what it was built to do. And according to Dr. David Sinclair, that single process is the root cause of heart disease, Alzheimer's, and most cancers. Not separate problems. The same problem, showing up in different places. The part that stopped me cold was what comes after that. If aging is information loss, it can be reversed by restoring the information. Dr. David Sinclair's lab has already done this in animals. When they restored the epigenetic signals, the cells remembered what they were. The aging reversed. Huberman asked whether the diseases go away too. Dr. David Sinclair did not hedge. " If you turn the clock back in tissues, those diseases go away." Every generation inherits assumptions about what the body can and cannot do. This one just changed. Follow @YourDocGoku for the science rewriting what we thought was permanent. David Sinclair

Goku

32,589 просмотров • 5 месяцев назад

David Sinclair just announced at the World Government Summit that next month (March 2026), human clinical trials begin — the first in history to test whether we can reverse aging and cure diseases. His core claim: Aging isn't wear-and-tear like a car; it's like scratches on a CD. DNA is the music, but in old age, cells can't read it correctly — leading to confusion, wrong proteins, and disease. The breakthrough? They can "polish the CD" via partial epigenetic reprogramming (using Yamanaka factors like OSK) to restore youthful gene expression without altering DNA itself. Science nugget: In lab and animal studies (published 2020–2025), Sinclair's team reversed epigenetic age by up to 75% in six weeks in mouse optic nerves, restoring vision in blind animals. The approach reactivates youthful gene patterns while avoiding full cellular reprogramming risks like tumors. Current status: The FDA cleared Life Biosciences' Phase 1 trial (ER-100, Sinclair co-founded) in January 2026 for safety in patients with optic neuropathies (e.g., glaucoma, NAION). Enrollment starts soon, with initial results expected by late 2026/early 2027. This targets eye disease first — not whole-body aging — but success could open doors to broader rejuvenation. Sinclair envisions a future where kids with cancer gather under gentle plasma lights that shatter tumors painlessly, one cell at a time. Sci-fi becoming science fact? Are you hopeful this trial delivers — or skeptical it's overhyped?

David Sinclair just announced at the World Government Summit that next month (March 2026), human clinical trials begin — the first in history to test whether we can reverse aging and cure diseases. His core claim: Aging isn't wear-and-tear like a car; it's like scratches on a CD. DNA is the music, but in old age, cells can't read it correctly — leading to confusion, wrong proteins, and disease. The breakthrough? They can "polish the CD" via partial epigenetic reprogramming (using Yamanaka factors like OSK) to restore youthful gene expression without altering DNA itself. Science nugget: In lab and animal studies (published 2020–2025), Sinclair's team reversed epigenetic age by up to 75% in six weeks in mouse optic nerves, restoring vision in blind animals. The approach reactivates youthful gene patterns while avoiding full cellular reprogramming risks like tumors. Current status: The FDA cleared Life Biosciences' Phase 1 trial (ER-100, Sinclair co-founded) in January 2026 for safety in patients with optic neuropathies (e.g., glaucoma, NAION). Enrollment starts soon, with initial results expected by late 2026/early 2027. This targets eye disease first — not whole-body aging — but success could open doors to broader rejuvenation. Sinclair envisions a future where kids with cancer gather under gentle plasma lights that shatter tumors painlessly, one cell at a time. Sci-fi becoming science fact? Are you hopeful this trial delivers — or skeptical it's overhyped?

Camus

22,434 просмотров • 6 месяцев назад

David Sinclair says he is a co-author of a paper with an AI system. It did not just validate what the field already knew. It found a new way to model biological age. The argument that AI can never be creative is just human arrogance.

David Sinclair says he is a co-author of a paper with an AI system. It did not just validate what the field already knew. It found a new way to model biological age. The argument that AI can never be creative is just human arrogance.

vitrupo

43,286 просмотров • 4 месяцев назад

David Sinclair says rapamycin had no measurable effect on slowing or reversing epigenetic aging in humans. This was a drug most of the longevity community supported. He was even a believer of it. It was found to extend lifespan in: • Inbred lab animals • Seemingly in dogs And everyone assumed it would translate to humans. Then a study came out about 6 months ago that compared the effect of different interventions on epigenetic age across multiple clinical trials. The results: • Caloric restriction = worked really well • Acarbose = worked really well • Metformin = "looked better than I thought it would" • Rapamycin = no effect on the age of the epigenome Zero. Nothing. Sinclair now takes rapamycin just four times a year while monitoring whether even that makes a difference. The most hyped longevity drug is being deprioritized by the scientist who is actually reversing aging. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

David Sinclair says rapamycin had no measurable effect on slowing or reversing epigenetic aging in humans. This was a drug most of the longevity community supported. He was even a believer of it. It was found to extend lifespan in: • Inbred lab animals • Seemingly in dogs And everyone assumed it would translate to humans. Then a study came out about 6 months ago that compared the effect of different interventions on epigenetic age across multiple clinical trials. The results: • Caloric restriction = worked really well • Acarbose = worked really well • Metformin = "looked better than I thought it would" • Rapamycin = no effect on the age of the epigenome Zero. Nothing. Sinclair now takes rapamycin just four times a year while monitoring whether even that makes a difference. The most hyped longevity drug is being deprioritized by the scientist who is actually reversing aging. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

John Cumbers

21,184 просмотров • 4 месяцев назад

The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to show that using [the information theory of aging] method we could cure blindness in animal for the first time." Since then, he also discovered you could treat and reverse diseases like Alzheimer's, multiple sclerosis, ALS, kidney disease and liver disease in mice too: “It's not just the eye that can get reversed and cured of diseases. It's seemingly every part of the body.” It's what he calls "a universal reset of the body." He confirmed his method also worked in monkeys. Now humans are next. The FDA just cleared the first age-reversal trial. Life Biosciences raised $80 million to make it happen. As he put it: "The eye is just the beginning. We believe we can treat every tissue—a whole body reset."

The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to show that using [the information theory of aging] method we could cure blindness in animal for the first time." Since then, he also discovered you could treat and reverse diseases like Alzheimer's, multiple sclerosis, ALS, kidney disease and liver disease in mice too: “It's not just the eye that can get reversed and cured of diseases. It's seemingly every part of the body.” It's what he calls "a universal reset of the body." He confirmed his method also worked in monkeys. Now humans are next. The FDA just cleared the first age-reversal trial. Life Biosciences raised $80 million to make it happen. As he put it: "The eye is just the beginning. We believe we can treat every tissue—a whole body reset."

John Cumbers

1,162,966 просмотров • 5 месяцев назад

Consistent endurance exercise may be one of the most powerful ways to slow down biological aging. Six months of cycling (about 4.5 hours/week) reduced GrimAge by 7 months relative to the expected trajectory of normal aging. GrimAge is an epigenetic clock tied to mortality risk. Participants also increased VO₂ max by ~20%, and the reduction in GrimAge tracked with those gains in cardiorespiratory fitness, but not with changes in body composition. The anti-aging signal seemed to come more from becoming fitter, not just leaner. To Prof Steve Horvath, this suggests biological aging is, at least to some extent, modifiable. We discuss how exercise may slow biological aging in the latest episode of the podcast. Out now.

Consistent endurance exercise may be one of the most powerful ways to slow down biological aging. Six months of cycling (about 4.5 hours/week) reduced GrimAge by 7 months relative to the expected trajectory of normal aging. GrimAge is an epigenetic clock tied to mortality risk. Participants also increased VO₂ max by ~20%, and the reduction in GrimAge tracked with those gains in cardiorespiratory fitness, but not with changes in body composition. The anti-aging signal seemed to come more from becoming fitter, not just leaner. To Prof Steve Horvath, this suggests biological aging is, at least to some extent, modifiable. We discuss how exercise may slow biological aging in the latest episode of the podcast. Out now.

Dr. Rhonda Patrick

81,809 просмотров • 2 месяцев назад

Curcumin may be one of the most powerful naturally occurring dietary compounds for lowering age-related inflammation Human studies show it can significantly reduce TNF-alpha, a major inflammatory cytokine that helps drive epigenetic and biological aging Because elevated TNF-alpha is linked to faster biological aging, lowering it may be one way curcumin supports healthier aging The phytosomal form is preferred because standard curcumin is rapidly broken down by the liver, while phytosomal delivery makes it far more bioavailable

Curcumin may be one of the most powerful naturally occurring dietary compounds for lowering age-related inflammation Human studies show it can significantly reduce TNF-alpha, a major inflammatory cytokine that helps drive epigenetic and biological aging Because elevated TNF-alpha is linked to faster biological aging, lowering it may be one way curcumin supports healthier aging The phytosomal form is preferred because standard curcumin is rapidly broken down by the liver, while phytosomal delivery makes it far more bioavailable

FoundMyFitness Clips

31,974 просмотров • 1 месяц назад

When Andrew Huberman asked about the root cause of aging, Dr. David Sinclair gave a surprisingly simple answer: "Aging is a loss of information in the same way you try to copy a cassette tape, or even if you send information across the internet, some of it will get lost." There are two types of information our bodies carry: "There is the genetic information, which is digital — A, T, C, G, the chemical letters of DNA. But there's this other part of the information in the body that's just as important, it's essential, in fact, and that's the systems that control which genes are switched on and off." And when it comes to which one matters more for how long and how well you live, the answer isn't even close: — David Sinclair

When Andrew Huberman asked about the root cause of aging, Dr. David Sinclair gave a surprisingly simple answer: "Aging is a loss of information in the same way you try to copy a cassette tape, or even if you send information across the internet, some of it will get lost." There are two types of information our bodies carry: "There is the genetic information, which is digital — A, T, C, G, the chemical letters of DNA. But there's this other part of the information in the body that's just as important, it's essential, in fact, and that's the systems that control which genes are switched on and off." And when it comes to which one matters more for how long and how well you live, the answer isn't even close: — David Sinclair

John Cumbers

305,874 просмотров • 5 месяцев назад

Michael Levin says aging may not just be a biology or physics problem. It’s a cognitive one. Almost like a boredom theory of aging. What happens when a system has nothing left to do?

Michael Levin says aging may not just be a biology or physics problem. It’s a cognitive one. Almost like a boredom theory of aging. What happens when a system has nothing left to do?

vitrupo

129,251 просмотров • 5 месяцев назад

"we take 92-year old human skin cells back to a biological age of around 25 using OSK." David Sinclair says AI could help make age reversal a reality. 👀 - AI screened up to 1 trillion molecules in just a few months, a task that would have taken hundreds to thousands of years using traditional drug discovery. - AI narrowed 1 trillion molecules to around 200 promising drug candidates for laboratory testing. - Researchers used Google DeepMind's AlphaFold protein predictions to virtually test molecules against human proteins before entering the lab. - AI is also helping determine whether human cells have become biologically younger simply by analyzing images of the cells. - Sinclair says his lab can already reprogram 92-year-old human skin cells to a biological age of around 20-25 using OSK partial cellular reprogramming. - "All my students can do this." - "It's not hard at all to reverse aging in isolated human cells." - "The hard part over the last 10 years has been turning it into a safe and effective drug for people." - Biological age is measured using DNA methylation clocks, which Sinclair says are more informative than relying only on telomeres. - Sinclair believes that one day you may no longer be able to tell how old someone is just by looking at them. - Sinclair says his team has early evidence that lost memories can return after brain rejuvenation, adding that the work has not yet been published. - He believes Alzheimer's patients may still retain their memories but have difficulty accessing them. - He believes making the entire body biologically younger could one day cure diseases that are currently incurable. 🤯 - He also said, making the entire body biologically younger could enable it to heal diseases that are currently incurable. Sinclair's approach is simple: "Make the body young, and it will heal itself."

"we take 92-year old human skin cells back to a biological age of around 25 using OSK." David Sinclair says AI could help make age reversal a reality. 👀 - AI screened up to 1 trillion molecules in just a few months, a task that would have taken hundreds to thousands of years using traditional drug discovery. - AI narrowed 1 trillion molecules to around 200 promising drug candidates for laboratory testing. - Researchers used Google DeepMind's AlphaFold protein predictions to virtually test molecules against human proteins before entering the lab. - AI is also helping determine whether human cells have become biologically younger simply by analyzing images of the cells. - Sinclair says his lab can already reprogram 92-year-old human skin cells to a biological age of around 20-25 using OSK partial cellular reprogramming. - "All my students can do this." - "It's not hard at all to reverse aging in isolated human cells." - "The hard part over the last 10 years has been turning it into a safe and effective drug for people." - Biological age is measured using DNA methylation clocks, which Sinclair says are more informative than relying only on telomeres. - Sinclair believes that one day you may no longer be able to tell how old someone is just by looking at them. - Sinclair says his team has early evidence that lost memories can return after brain rejuvenation, adding that the work has not yet been published. - He believes Alzheimer's patients may still retain their memories but have difficulty accessing them. - He believes making the entire body biologically younger could one day cure diseases that are currently incurable. 🤯 - He also said, making the entire body biologically younger could enable it to heal diseases that are currently incurable. Sinclair's approach is simple: "Make the body young, and it will heal itself."

SciTech Era

10,180 просмотров • 27 дней назад

David Eby says he has “NO INFORMATION” that India is involved in extortion in B.C. If the Premier truly has no information… That might be the BIGGEST problem of all.

David Eby says he has “NO INFORMATION” that India is involved in extortion in B.C. If the Premier truly has no information… That might be the BIGGEST problem of all.

Marc Nixon

23,616 просмотров • 6 месяцев назад