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The force of blood flow generated during vigorous-intensity exercise kills circulating tumor cells Vigorous exercise creates high shear stress inside blood vessels (a mechanical force that damaged cancer cells are uniquely vulnerable to, pushing them toward cell death) These are the same cells responsible for cancer recurrence and metastasis...

31,023 görüntüleme • 6 ay önce •via X (Twitter)

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🚨🚨 Ivermectin and mebendazole attack cancer cells in many different ways. Chemotherapy usually attacks only one.... Cancer has to be attacked through multiple mechanisms simultaneously... Ivermectin and mebendazole together do exactly that: they block cell division, cut off glucose metabolism, target cancer stem cells, and much more... Dr. Peter McCullough. 💊 IVERMECTIN – 12 Known Anti-Cancer Actions: 1. Inhibits the WNT/β-catenin pathway: stops the proliferation of cancer cells. 2. Induces apoptosis: triggers programmed death of cancer cells. 3. Blocks importin α/β transporter proteins, preventing replication of cancer cells. 4. Inhibits the PAK1 enzyme: reduces inflammation and tumor progression. 5. Antiangiogenic: stops the formation of new blood vessels in tumors. 6. Immune system modulator: improves recognition of cancer cells. 7. Autophagy disruptor: interferes with cancer cells' survival strategies. 8. Targets glioblastoma stem cells: effective in brain cancers. 9. Inhibits mitochondrial respiration: cuts off energy supply to tumors. 10. Disrupts mTOR signaling, slowing cell growth. 11. Overcomes chemotherapy resistance: makes chemotherapy more effective. 12. Antiviral properties: potentially useful for virus-related cancers (like HPV). 💊 MEBENDAZOLE – 12 Known Anti-Cancer Action: 1. Microtubule destabilization: similar to fenbendazole 2. Inhibits angiogenesis and blocks the growth of new blood vessels. 3. Triggers apoptosis: causes the death of cancer cells. 4. Inhibits VEGF signaling: blocks blood supply signals to the tumor. 5. Crosses the blood-brain barrier: useful for brain cancers. 6. Activates caspase-3/7 enzymes, involved in programmed cell death. 7. Reduces expression of the MYC oncogene, slowing tumor growth. 8. Inhibits the Bcl-2 protein, reducing cancer cell survival. 9. Anti-metastatic: reduces cancer spread. 10. Alters mitochondrial function: impairs energy production in tumor cells. 11. Improves chemotherapy sensitivity: helps standard treatments work better. 12. Low toxicity + long safety history: used in humans for decades. Follow me for more Bombshell.

Joe Tippens

25,359 görüntüleme • 12 gün önce

🔴Ivermectin and mebendazole attack cancer cells in many different ways. Chemotherapy usually attacks only one.... Cancer has to be attacked through multiple mechanisms simultaneously... Ivermectin and mebendazole together do exactly that: they block cell division, cut off glucose metabolism, target cancer stem cells, and much more... Dr. Peter McCullough. IVERMECTIN – 12 Known Anti-Cancer Actions: 1. Inhibits the WNT/β-catenin pathway: stops the proliferation of cancer cells. 2. Induces apoptosis: triggers programmed death of cancer cells. 3. Blocks importin α/β transporter proteins, preventing replication of cancer cells. 4. Inhibits the PAK1 enzyme: reduces inflammation and tumor progression. 5. Antiangiogenic: stops the formation of new blood vessels in tumors. 6. Immune system modulator: improves recognition of cancer cells. 7. Autophagy disruptor: interferes with cancer cells' survival strategies. 8. Targets glioblastoma stem cells: effective in brain cancers. 9. Inhibits mitochondrial respiration: cuts off energy supply to tumors. 10. Disrupts mTOR signaling, slowing cell growth. 11. Overcomes chemotherapy resistance: makes chemotherapy more effective. 12. Antiviral properties: potentially useful for virus-related cancers (like HPV). MEBENDAZOLE – 12 Known Anti-Cancer Action: 1. Microtubule destabilization: similar to fenbendazole 2. Inhibits angiogenesis and blocks the growth of new blood vessels. 3. Triggers apoptosis: causes the death of cancer cells. 4. Inhibits VEGF signaling: blocks blood supply signals to the tumor. 5. Crosses the blood-brain barrier: useful for brain cancers. 6. Activates caspase-3/7 enzymes, involved in programmed cell death. 7. Reduces expression of the MYC oncogene, slowing tumor growth. 8. Inhibits the Bcl-2 protein, reducing cancer cell survival. 9. Anti-metastatic: reduces cancer spread. 10. Alters mitochondrial function: impairs energy production in tumor cells. 11. Improves chemotherapy sensitivity: helps standard treatments work better. 12. Low toxicity + long safety history: used in humans for decades. Follow me for more Bombshell.

Commentary | Global Ivermectin Research Hub

23,589 görüntüleme • 10 gün önce

The current physical activity guidelines undervalue vigorous activity. Vigorous activity may be 4–9× more potent than moderate activity for reducing all-cause mortality, cardiovascular disease, diabetes, and cancer risk. The exercise guidelines assume a 2:1 ratio between moderate- and vigorous-intensity activity: two minutes of moderate activity equals one minute of vigorous. That's why the recommendations are 150–300 minutes of moderate or 75–150 minutes of vigorous activity each week. But new data suggest that ratio is wrong. In this brand-new journal-club episode, Brady Holmer (Brady Holmer) and I unpack a groundbreaking study that should change how we think about activity for disease prevention. The research identified that 1 minute of vigorous activity is roughly equivalent to 4–9 minutes of moderate activity, and 53–94 minutes of light activity, for disease risk reduction. It also shows a clear dose-response for vigorous activity that’s much weaker for moderate activity and barely detectable for light activity. We also do a deep dive into why vigorous activity is so powerful, the underlying mechanisms, and discuss practical takeaways, including how even very brief bouts of vigorous movement (think “exercise snacks”) can produce meaningful health benefits. Timestamps are below. You can find links to the episode on YouTube, Apple Podcasts, and Spotify in the next post. Enjoy! Timestamps: 0:00 - Introduction 2:14 - The 1:2 rule for exercise 6:28 - What counts as vigorous? 8:48 - Where exercise guidelines fail 9:32 - Inside the wearable-based study design 15:24 - Vigorous activity—easier than you think? 18:01 - Avoiding healthy user bias 19:12 - A better way to measure exercise 20:58 - Is vigorous 4–10x better? 25:08 - One vigorous min vs. one-hour walk 27:15 - Are light activity's benefits capped? 29:03 - Is vigorous 5x better for your heart? 30:12 - Does zone 2 count as vigorous? 31:24 - Dose-response comparison 32:35 - Vigorous exercise & younger arteries 38:29 - Why aging hearts need intensity 41:22 - Can intensity preserve VO₂ max? 42:40 - Moderate exercise & VO₂ max limits 44:34 - Is vigorous 10x better for diabetes? 51:01 - Why intensity boosts mitochondria 56:11 - Does intense exercise kill tumor cells? 1:02:28 - Hormonal benefits 1:03:19 - Preventing falls with intensity 1:07:49 - Fighting inflammation 1:09:42 - High-intensity training & brain aging 1:11:14 - The 2:1 ratio is out the door 1:13:03 - Could vigorous exercise become a pill? 1:14:21 - Short bursts for longer life 1:18:28 - Can short bouts match full workouts? 1:22:39 - Do wearables undervalue vigorous bursts? 1:25:19 - Can micro-workouts replace the gym? 1:30:23 - Updating exercise guidelines 1:41:48 - Is light activity useless? 1:44:17 - Is vigorous exercise safe for seniors? 1:48:41 - Is HIIT harmful to female hormones? 1:54:18 - Balancing intensity & recovery (80/20 rule) 1:56:43 - Brady’s exercise routine 2:00:30 - Vigorous activity & kids’ brainpower 2:03:27 - Are we undervaluing vigorous exercise? 2:05:16 - Why chasing steps doesn't work

Dr. Rhonda Patrick

305,879 görüntüleme • 6 ay önce

Research suggests that up to 40% of cancer cases could be prevented through lifestyle changes. The evidence is now overwhelming: exercise is not just supportive—it’s a therapeutic intervention that recalibrates tumor biology, enhances treatment tolerance, and improves survival outcomes. Today’s interview features Dr. Kerry Courneya. With over 600 peer-reviewed studies, he is one of the most influential figures in exercise oncology. Even if you aren't someone who has personally experienced cancer in one form or another, you need to watch this episode. Episode 99 is Available now on X, YouTube, Spotify, and Apple Podcasts. Chapters: 0:00 - Introduction 1:47 - Why exercise should be effortful 2:33 - How to meaningfully reduce risk of cancer 6:22 - What type of exercise is best? 7:59 - How exercise reduces risk—even for smokers and the obese 10:48 - Weekend-only exercise 13:49 - 150 vs. 300 minutes per week (more is better—up to a point) 16:03 - Why pre-diagnosis exercise matters 19:09 - Why resilience to cancer treatment starts with exercise 21:01 - Why low muscle mass drives cancer death 23:58 - Why BMI fails to measure true obesity 27:51 - Why daily activity isn't enough (structured exercise matters) 29:34 - Breaking up sedentary time—do ‘exercise snacks’ help? 31:50 - Supplements vs. exercise 32:32 - Where exercise fits with chemo and immunotherapy 35:30 - Why rest is not the best medicine 41:20 - Aerobic vs. resistance 42:13 - How weight training improves 'chemo completion' 44:41 - Why exercise creates vulnerability in cancer cells (limitations do apply) 47:09 - Why exercise might be crucial for tumor elimination 53:03 - Why cardio may be better at clearing tumor cells 56:18 - When cancer spreads quickly—and when it doesn't 57:43 - Why liquid biopsies may prevent over-treatment 1:02:56 - Exercise-sensitive vs. exercise-resistant cancers 1:06:06 - Prostate cancer therapy—why strength training matters 1:08:10 - When exercise is the only therapy—does it work? 1:09:26 - Why HIIT reduces PSA in prostate cancer 1:11:40 - Avoiding overtreatment—can exercise buy you time? 1:12:00 - Why high-intensity exercise boosts anti-cancer biology 1:13:11 - Turning a diagnosis into a wake-up call 1:16:11 - Why oncologists are rethinking exercise 1:18:50 - Why exercise eases anxiety about cancer—proven psychological benefits 1:25:00 - Before, during, and after treatment 1:27:02 - Why exercise is unique among cancer therapies 1:28:16 - Why cancer patients stop exercising—the risky mistake almost everyone makes 1:30:41 - How to get sedentary cancer patients exercising (realistically) 1:33:15 - The $1 million case for including exercise 1:34:56 - Why recurrence trials haven't convinced doctors—yet 1:37:36 - The bottom-line message 1:37:55 - The myth of a cancer panacea (exercise included) 1:44:07 - What's the best $50 investment for staying active? 1:44:40 - Only 15 minutes per day—what’s the best anti-cancer exercise?

Dr. Rhonda Patrick

219,784 görüntüleme • 1 yıl önce

🚨Here's what a lot of people misunderstand about cancer treatment, says drpaulmarik: "Cancer is not homogeneous. The somatic mutation theory—which is the current theory in which treatment is based—posits that you have a mutation in a single cell, and that gives rise to a whole population of cells that look the same and have the same mutation. But the Cancer Genome Atlas has shown that that theory is completely wrong. The cancer cells are very heterogeneous, so they're made up of very different populations of cells with different mutations, and one of the populations is the cancer stem cell. It's a sub-population of the cancer. These are generally slow-growing, but they're distinct in that they have the ability to divide indefinitely and grow indefinitely, and can change their characteristics. Basically, if you get rid of the fast-dividing cells, which is the cancer, you're left with the stem cells, which then become the roots, which grow back to form the tumor" sometimes years later. Conventional chemotherapy gets rid of the fast-dividing regular cancer cells but *NOT* the stem cells. So the key question is: how do you get rid of the stem cells? “There are a number of repurposed drugs that do it, and this has been well-established in scientific medical literature. One of the most effective treatments to knock out the stem cell is the famous horse deworming medicine," says drpaulmarik. Yes, ivermectin. Independent Medical Alliance

Jan Jekielek

96,002 görüntüleme • 1 yıl önce

Why Are We Ignoring the One Cell That Kills Cancer? Dr. Patrick Soon-Shiong Exposes 50 Years of Flawed Dogma Dr. Patrick Soon-Shiong, renowned physician, scientist, and innovator in cancer research, is calling for a paradigm shift in how we approach cancer treatment. For over fifty years, the standard protocol—chemotherapy, radiotherapy, steroids, and checkpoint inhibitors—has dominated oncology. Yet, as Dr. Soon-Shiong passionately argues, this approach may be winning battles but losing the war against cancer. Consider a simple experiment: call any random oncologist or primary care physician and ask about a complete blood count (CBC), a routine blood screen used to monitor patients during cancer treatment. The focus is typically on red blood cells (to check for anemia), platelets (to assess clotting risks), and neutrophils (to prevent infections like neutropenic fever). Drugs like Epogen, platelet transfusions, and Neupogen are prescribed to address these issues. But do red blood cells, platelets, or neutrophils kill cancer? No. The cells that fight cancer—natural killer cells and T-cells, collectively known as lymphocytes—are largely ignored. Dr. Soon-Shiong highlights a startling reality: 99.9% of oncologists do not prioritize lymphocytes in a CBC, despite their critical role in destroying cancer cells. “This is the missing link,” he says, “the final frontier, the E=mc² of cancer treatment.” For decades, the medical community has overlooked the very cells that could hold the key to long-term victory over cancer. Worse, standard treatments like chemotherapy and radiotherapy often destroy these vital lymphocytes, while steroids and checkpoint inhibitors further impair their function. The result? A short-term “blip” of tumor reduction, followed by aggressive cancer recurrence and metastasis. Dr. Soon-Shiong’s observations resonate with a grim pattern many have witnessed: patients declared “in remission” only to face a devastating wave of cancer months later. “You win the battle, but you lose the war,” he notes, pointing to the upregulation of suppressor cells and the destruction of protective immune cells as culprits. This cycle, perpetuated by decades of dogma, has led countless patients to hospice when their immune systems, stripped of their natural defenses, can no longer fight. The time for change is now. Dr. Soon-Shiong urges the medical community to rethink cancer treatment by prioritizing the immune system’s natural warriors—lymphocytes—and developing therapies that enhance, rather than destroy, their function. This is not just a critique; it’s a call to action to break free from fifty years of flawed assumptions and embrace a new era of cancer care. Join Dr. Patrick Soon-Shiong in challenging the status quo. Let’s stop fighting against the body’s own defenses and start harnessing them to win the war against cancer.

Camus

35,185 görüntüleme • 1 yıl önce

Cancer Is Largely Preventable—Here’s the Science-Backed Solution For decades, we’ve been told cancer is a genetic disease—inescapable, unpredictable, a roll of the dice. But what if that’s wrong? Dr. Thomas Seyfried, a leading cancer researcher, reveals a paradigm-shifting truth: Cancer is a metabolic disease, fueled by the very foods and lifestyles we’ve been conditioned to accept. 🔬 The Science Doesn’t Lie: - High blood sugar = Faster tumor growth. - Low blood sugar = Slower tumor growth. - Cancer cells thrive on glucose & glutamine—but they can’t efficiently use ketones. The Solution? Starve the Tumor. Cancer cells have broken mitochondria, forcing them to rely on fermentation (sugar & glutamine) for survival. But healthy cells can thrive on ketones. This is the key. ✅ How to Shift the Battlefield: 1. Water-only fasting – Deprives tumors of fuel. 2. Ketogenic diet – Replaces glucose with ketones, starving cancer while nourishing the body. 3. Exercise & mitochondrial health – Vigorous movement repairs cellular energy systems. 4. Ditch processed carbs – They feed dysfunction at the deepest level. The result? Tumors lose their energy supply, blood vessels shrink, and the body naturally dismantles them. 🔥 This isn’t theory—it’s biochemistry. The war on cancer isn’t about toxic drugs or blind luck. It’s about controlling the metabolic environment. Want to slash your risk? ✔ Fast strategically. ✔ Go low-carb, high-fat. ✔ Move like your life depends on it. Cancer isn’t just “bad genes.” It’s bad metabolism. And that means you have power over it. — Dr. Thomas Seyfried

Camus

290,599 görüntüleme • 11 ay önce