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New: Joe Rogan is visibly concerned when longevity scientist David Sinclair reveals that the first potential human age-reversal technology is already being tested in humans: ROGAN: “This sounds like the beginning of a horror movie.” SINCLAIR: “I admit it is science fiction, and I even have to pinch myself...

26,737 views • 13 days ago •via X (Twitter)

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Joe Rogan is stunned by a theory that could completely rewrite human history: an advanced civilization may have existed LONG before recorded history. ROGAN: “There was a very advanced civilization that existed on Earth tens of thousands of years ago.” ROGAN: “We were probably wiped out by a comet impact, and what we have today is a rebuild of civilization.” ROGAN: “There’s not a linear progression from caveman to us.” ROGAN: “When you look at the Sumerian kings list, it gets very weird because there’s kings that reign for thousands of years.” ROGAN: “And then you have the flood. After the flood, the age of these people drops pretty dramatically.” ROGAN: “Is this just myth? Poor recordkeeping? Or had they achieved something we don’t understand?” ROGAN: “They had achieved incredibly complex structures like the pyramids.” ROGAN: “How did they move these 500-ton stones from hundreds of miles away? We don’t really know.” ROGAN: “Had they also gotten involved in genetic engineering?” ROGAN: “Had they figured out a way to extend lifespan?” Then Sinclair takes the idea even further. SINCLAIR: “Imagine if you had 500 years to do research, not just 57 years.” SINCLAIR: “Imagine if you could continue learning and growing.” SINCLAIR: “You would get so much done.” SINCLAIR: “The exponential increase in technological innovation that we would have in this society would be absolutely mind-blowing.” SINCLAIR: “If we do have extension of human lifespan… how will you think about your life if being 100 is still your prime?” SINCLAIR: “You might have multiple lifetimes, multiple marriages, multiple families.” SINCLAIR: “That will happen. It’s not really a question of if anymore.”

gomi

120,856 views • 10 days ago

Joe Rogan yells "Holy sh*t!" after Harvard professor of genetics David Sinclair says sudden blindness has DOUBLED because of GLP-1 drugs. Then Rogan pulls up the data himself — and what he reads out loud is even worse. SINCLAIR: "Glaucoma and also sudden blindness. It's called NAION, which is now twice as more prevalent because of the GLP-1 drugs." ROGAN: "Really?!" SINCLAIR: "It's not well known. Obviously companies don't want to talk about it. But yes, sudden blindness has doubled, seemingly because of these meds." ROGAN: "Holy shit!" SINCLAIR: "Careful." ROGAN: "Sudden blindness has doubled because of GLP-1s?" SINCLAIR: "Due to NAION, which is like a stroke in your eye, and then your other eye can go. Which is pretty scary. And there's nothing you can do about it. Hopefully our drug does work for those people." ROGAN: "And, obviously correlation does not equal causation, but it seems to be." SINCLAIR: "Yeah, there's a scientist at Harvard. You could look up his work. Joe Rizzo. It looks like it's repeatable across the planet." ROGAN: "Wow, that's terrible. Terrible because there's so many people out there that are just telling everyone they should get on GLP-1s… Like online podcasters saying, 'Everyone should get on GLP-1s… It's going to transform society.' I'm like, 'We just started taking these! The f*ck are you saying?!'" SINCLAIR: "Yeah, it's not risk free. Same with ED drugs." ROGAN: "Here goes. Recent studies suggest that a potential risk — rare link between GLP-1 receptor agonist medications such as Ozempic, Wegovy, blah, blah, blah, and… an eye stroke [that] can cause sudden, painless loss of vision in one eye, while absolute risk remains very low." ROGAN: "Well, very low is like… What does that mean?" SINCLAIR: "One in 10,000 people." ROGAN: "One in 10,000?" SINCLAIR: "Oh no. Total of 10,000." ROGAN: "Oh, total of 10,000 so far? How many people are taking this stuff?" [Rogan continues reading] "The drugs were 68.6 times more likely to develop this [eye stroke] and 8 times more likely to develop… diabetic retinopathy." ROGAN: "Oh, my God. Then… Wow." ROGAN: "Yeah, man. These things are just — they're just rolling out…"

The Vigilant Fox 🦊

1,504,217 views • 13 days ago

David Sinclair says the first person to live to 150 is a teenager who's alive today. He's taken flak from colleagues for years over this prediction. He doesn't care. He still stands by it. "The first person to live to 150 has already been born." Here's why: A 14-year-old today has 80+ years of exponential technological progress ahead of them. Just look at what's happened in the last 10 years: • His lab reversed aging in monkey eyes by 95% • AI now does in 2 months what would have taken thousands of years. • His team has oral molecules that made old mice young again in 4 weeks • The first human age-reversal trial begins in January And that's just the beginning. There'll be more advancements in major medical technologies and therapies soon, including in: • Gene therapy • AI-designed drugs • Whole-body rejuvenation • Epigenetic reprogramming All of it will arrive within a teenager's lifetime. Sinclair believes this is a realistic projection of where the science is heading. Sinclair's advice for everyone is to stay healthy long enough to intercept what's coming. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

John Cumbers

84,263 views • 4 months ago