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Is biological aging actually reversible? De Grey believes it will eventually be possible. Kaeberlein is the complete opposite: "I think it's almost impossible, if not impossible, to completely reverse biological aging." His reason is simple. "You can't reverse entropy." However, does believe you can improve health and parts of...

24,223 views • 3 months ago •via X (Twitter)

24 Comments

Aubrey de Grey's profile picture
Aubrey de Grey3 months ago

Hehe. Whenever someone says that Matt and I have completely opposite beliefs about some question in the field, you can be absolutely sure that they are oversimplifying. On this question, Matt and I entirely agree; it's all a matter of how much of the damage of aging 1) can be repaired today, 2) is likely to be repairable in the foreseeable future, 3) needs to be repaired to reach LEV, and 4) needs to be repaired in order that we can say "biological aging has been COMPLETELY reversed". If that had been the question, it's absolutely certain that both my and Matt's answers would have been, respectively: a minority, a majority, a majority, and all of it. The only sliver of disagreement we would have is whether the "majority" in question 3 is larger than the one in question 2 - and even there it hinges on what we each mean by "foreseeable". As Matt makes clear, he was choosing to answer question 4, whereas I was answering question 3.

Rand's profile picture
Rand3 months ago

agreed as of today but we have already had results that I think push back

Baron Fitzwalter's profile picture
Baron Fitzwalter3 months ago

“You can’t reverse entropy”. A fundamental of thermodynamics is that in an isolated system entropy will increase. But a human body subject to health interventions is not an isolated system. The entropy in the system can be reduced by increasing entropy outside the system

David Black's profile picture
David Black3 months ago

What a silly take about entropy. Without entropy you don’t have the complex novelty that life creates. Physical immorality is absolutely possible because engineering exists.

Wanderer of the Stars's profile picture
Wanderer of the Stars3 months ago

By Kaeberlein's logic, we can't fix cars. Ridiculous.

Aris | K-Shaped Capital's profile picture
Aris | K-Shaped Capital3 months ago

Yeah but he is wrong because there are animals that apparently reverse entropy

bitflipgremlin's profile picture
bitflipgremlin3 months ago

>"You can't reverse entropy." tell that to my AC that is quite literally a thermal entropy generator that claim only stands for closed systems. the human body is absolutely not a closed system as evidenced by the fact that you eat food and excrete shit

Julian Issa's profile picture
Julian Issa3 months ago

If you'd like to watch the full interview, it's out on YT: We also covered: • Why billionaires aren't funding the field • Whether NAD infusions actually do anything • The one red flag to check on any peptide before using it Click here:

Catalin C's profile picture
Catalin C3 months ago

Entropy's a one-way street, but research keeps pushing the boundaries.

Mac /dd/lev's profile picture
Mac /dd/lev3 months ago

it’s possible, the best combinitorics are being tested in humans now for the first time.

Andrej Szontagh's profile picture
Andrej Szontagh3 months ago

Well, entropy is technically reversible, if you know where all the pieces were before you can put them back. We are not an inanimate objects.

Koala's profile picture
Koala3 months ago

What about the immortal jellyfish? Biology is more modifiable than what one might think

Gaius Cornelius Tacitus's profile picture
Gaius Cornelius Tacitus3 months ago

My money on sinclair

experience's profile picture
experience3 months ago

That’s retarded as fuck. You can actually reverse entropy locally, the second law only applies to closed systems. Hope this guy doesn’t have a physics degree.

murat's profile picture
murat3 months ago

i was thinking like De grey 2-3 years before. But when i see that everything is going very very very slower; even if it is sad , i am thinking like Kaeberlain anymore. wee will all die

Lorenz S.'s profile picture
Lorenz S.3 months ago

He's wrong. With his claim there would be neither a brain nor AI or any other model.

ATChaisson's profile picture
ATChaisson3 months ago

No, Age reversal is not possible. Even when the ancients imbibed Ambrosia and Nectar, they remained the same biological age. Otherwise, Zeus would have appeared as a young man, and not how we depict him, an old man with white hair and beard. Aging is not a disease. It's a patina. The older you get, the more you realize that.

Invicta's profile picture
Invicta3 months ago

Idk the system avoids entropy pretty well over decades, that’s pretty close already to immortality given you’re already 99.9% there in terms of self maintenance.

Freedom forever 🇮🇳's profile picture
Freedom forever 🇮🇳3 months ago

Matt @mkaeberlein needs to change his opinion now.

M's profile picture
M3 months ago

I guess it depends partly on how strict your definitions are.

𝔾𝕖𝕒𝕣 𝕄𝕖𝕟𝕥𝕒𝕥𝕚𝕠𝕟's profile picture
𝔾𝕖𝕒𝕣 𝕄𝕖𝕟𝕥𝕒𝕥𝕚𝕠𝕟3 months ago

Why is this idiot getting attention?

Jamie_NYC's profile picture
Jamie_NYC3 months ago

What? You can’t reduce entropy in an open system?

dario1122's profile picture
dario11223 months ago

Que entropia? En ratones ya se consiguió

hi530's profile picture
hi5303 months ago

First, you can reverse entropy in an open system. Second, for a CLOSED system, THERE IS AS YET INSUFFICIENT DATA FOR A MEANINGFUL ANSWER

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